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| 1 | 为用离合器切割器的食道的小粒的房间肿瘤的内视镜的 submucosal 解剖显示文摘 Endoscopic submucosal dissection (ESD) with a knife is a technically demanding procedure associated with a high complication rate.The shortcomings of this method are the deficiencies of fixing the knife to the target lesion,and of compressing it.These shortcomings can lead to major complications such as perforation and bleeding.To reduce the risk of complications related to ESD,we developed a new grasping type scissors forceps (Clutch Cutter,Fujifilm,Japan) which can grasp and incise the targeted tissue using an electrosurgical current.Esophagogastroduodenoscopy on a 59-year-old Japanese man revealed a 16mm esophageal submucosal nodule with central depression.Endoscopic ultrasonography demonstrated a hypoechoic solid tumor limited to the submucosa without lymph node involvement.The histologic diagnosis of the specimen obtained by biopsy was granular cell tumor.It was safely and accurately resected without unexpected incision by ESD using the CC.No delayed hemorrhage or perforation occurred.Histological examination confirmed that the granular cell tumor was completely excised with negative resection margin.We report herein a case of esophageal granular cell tumor successfully treated by an ESD technique using the CC. | Keishi Komori Kazuya Akahoshi Yoshimasa Tanaka Yasuaki Motomura Masaru Kubokawa Soichi Itaba Terumasa Hisano Takashi Osoegawa Naotaka Nakama Risa Iwao Masafumi Oya Kazuhiko Nakamura | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，1： | 8 |
| 2 | Screening of agonistic activities against four nuclear receptors in wastewater treatment plants in Japan using a yeast two-hybrid assay显示文摘To assess the potential endocrine disruptive effects through multiple nuclear receptors(NRs),especially non-steroidal NRs,in municipal wastewater,we examined the agonistic activities on four NRs(estrogen receptor α,thyroid hormone receptor α,retinoic acid receptor α and retinoid X receptor α) of untreated and treated wastewater from municipal wastewater treatment plants(WWTPs) in Japan using a yeast two-hybrid assay.Investigation of the influent and effluent of seven WWTPs revealed that agonistic activities against steroidal and non-steroidal NRs were always detected in the influents and partially remained in the effuents.Further investigation of four WWTPs employing conventional activated sludge,pseudo-anoxic-oxic,anoxic-oxic and anaerobic-anoxic-oxic processes revealed that the ability to reduce the agonistic activity against each of the four NRs varies depending on the treatment process.These results indicated that municipal wastewater in Japan commonly contains endocrine disrupting chemicals that exert agonistic activities on steroidal and non-steroidal NRs,and that some of these chemicals are released into the natural aquatic environment.Although the results obtained in yeast assays suggested that measured levels of non-steroidal NR agonists in the effluent of WWTPs were not likely to cause any biological effect,further study is required to assess their possible risks in detail. | Daisuke Inoue Koki Nakama Kazuko Sawada Taro Watanabe Hisae Matsui Kazunari Sei Tsuyoshi Nakanishi Michihiko Ike | 2011 | Journal of Environmental Sciences2011，23，1： | 2 |
| 3 | Reactive and non-reactive transport modelling in partially water saturated argillaceous porous media around the ventilation experiment,Mont Terri显示文摘At Mont Terri Underground Research Laboratory (URL) Switzerland, a specific experiment has been performed in a tunnel, in order to investigate the hydro-mechano-chemical (HMC) perturbations induced in the argillaceous formation by forced ventilation. This experiment has been selected in the international project DECOVALEX to be used for process model development and validation. The numerical simulation of the geochemical response to the ventilation experiment (VE) is the object of the present paper, focusing on the transport of chloride as a conservative species and sulphate as a reactive species. Utilising the validated hydro-mechanical (HM) results from earlier steps of the DECOVALEX task, reactive and non-reactive transport models, incorporating the current understanding of the geochemistry at the site, were successfully constructed for the whole experimental period. The associated parametric and process uncertainty analyses clearly demonstrate that the basic HM understanding must be sound. However, to demonstrate this degree of robustness, the explicit inclusion of process representations of water desaturation, liquid vaporisation, species exclusion porosity, and redox processes, is required. | Alexander Bond Steven Benbow James Wilson Alain Millard Shigeo Nakama Myles English Christopher McDermott Benoit Garitte | 2013 | Journal of Rock Mechanics and Geotechnical Engineering2013，5，1： | 2 |
| 4 | Surgical treatments for multiple primary adenocarcinoma of the lung显示文摘 | Nakama M sawada S Yamashita M | 2004 | Ann Thorac Surg2004，78，： | 1 |
| 5 | Encapsulation cell therapy for mucopolysaccharidosis type Ⅶ using genetically engineered immortalized human amniotic epithelial cells显示文摘 | Nakama H Ohsuqi K Otsuki T | 2006 | Tohoku J Exp Med2006，209，1： | 1 |
| 6 | Estimation of electron probe profile from SEM image through wavelet multiresolution analysis for inline SEM inspection显示文摘 | Nakamae Koji Chikahisa Masaki Fujioka Hiromu | 2007 | Image and Vision Computing2007，25，7： | 1 |
| 7 | Insight and quality of life in long-term hospitalized Japanese patients with chronic schizophrenia 显示文摘 | Nakamae T Kitahayashi Y Okamura A | 2010 | Psychiatry Clin Neurosci2010，64，4： | 1 |
| 8 | Fast Photo-Realistic Rendering of Trees in Daylight 显示文摘 | Qin X Y Nakamae E Tadamura K | 2003 | Computer Graphics Forum (S0167-7055)2003，22，3： | 1 |
| 9 | Certified sediment reference materials for trace element analysis from the National Metrology Institute of Japan (NMIJ)显示文摘 | Kazumi Inagaki Akiko Takatsu Takayoshi Kuroiwa Atsuko Nakama Sakae Eyama Koichi Chiba Kensaku Okamoto | 2004 | Analytical and Bioanalytical Chemistry2004，，5： | 1 |
| 10 | The Lowest Surface Free Energy Based on - CF3 Alignment 显示文摘 | Nishino T Meguro M Nakamae K | 1999 | Langmuir1999，15，13： | 1 |
| 11 | An ultrastructural study on the ligamentum flavum of the cervical spine in patients with os- sification of the posterior longitudinal ligament显示文摘 | Nakama S Ihara T Sugamata M | 2006 | Med Mol Mor- phol2006，39，： | 1 |
| 12 | Biomolecule-sensitive hydrogels 显示文摘 | Miyata T Uragami T Nakamae K | 2002 | Advanced Drug Delivery Reviews2002，54，1： | 1 |
| 13 | Efficacy of Percutaneous Vertebroplasty in the Treatment of Osteoporotic Vertebral Compression Fractures with lntravertebral Cleft 显示文摘 | Nakamae T Fujimoto Y Yamada K | 2015 | Open Orthop J2015，9，： | 1 |
| 14 | The lowest surface free energy based on -CF3 alignment显示文摘 | NISHINO T MEGURO M NAKAMAE K | 1999 | Langmuir1999，15，： | 1 |
| 15 | Design improvements on graded insulation of power transformers using transient electric field analysis and visualization technique显示文摘 | Yamashita H Cingoski V Nakamae E | 1999 | IEEE Transactions on Energy Conversion1999，14，4： | 1 |
| 16 | Successful treatment with rltuximab and thalidomide of POEMS syndrome associ- ated with Waldenstrom macroglobulinemia 显示文摘 | Kawano Y Nakama T Hata H et aI | 2010 | J Neurol Sci2010，，12： | 1 |
| 17 | Cervical muscle strength after laminoplasty显示文摘 | Sueo Nakama Kikuko Natanai Yoichi Oohashi | 2003 | J Orthop Sei2003，8，1： | 1 |
| 18 | Efetio da alternaneia de temperaturas no desenvolvimento e emergancia de Trissolcus basalis (Wollaston) e Telenomus podisi Ashmead (Hymenoptera:Scelionidae) 显示文摘 | Nakama P A Foerster L S A | 2001 | Neotropical Entomology2001，30，2： | 1 |
| 19 | Detection of agonistic activities against five human nuclear receptors in river environments of Japan using a yeast two-hybrid assay显示文摘 | Lnoue D Nakama K Matsui H | 2009 | Bulletin of Environmental Contamination and Toxicology2009，82，4： | 1 |
| 20 | An AB block copolymer of oligo(methyl methacrylate) and poly(acrylic acid) for micellar delivery of hydrophobic drug显示文摘 | Inoue T Chen G Nakamae K | 1998 | J Controlled Release1998，51，： | 1 |
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