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| 1 | Roux-en-Y versus BillrothⅠreconstruction after distal gastrectomy for gastric cancer:A meta-analysis显示文摘AIM:To conduct a meta-analysis to compare Rouxen-Y(R-Y) gastrojejunostomy with gastroduodenal Billroth Ⅰ(B-Ⅰ) anastomosis after distal gastrectomy(DG) for gastric cancer.METHODS:A literature search was performed to identify studies comparing R-Y with B-Ⅰ after DG for gastric cancer from January 1990 to November 2012 in Medline,Embase,Science Citation Index Expanded and the Cochrane Central Register of Controlled Trials in The Cochrane Library.Pooled odds ratios(OR) or weighted mean differences(WMD) with 95%CI were calculated using either fixed or random effects model.Operative outcomes such as operation time,intraoperative blood loss and postoperative outcomes such as anastomotic leakage and stricture,bile reflux,remnant gastritis,reflux esophagitis,dumping symptoms,delayed gastric emptying and hospital stay were the main outcomes assessed.Meta-analyses were performed using RevMan 5.0 software(Cochrane library).RESULTS:Four randomized controlled trials(RCTs) and 9 non-randomized observational clinical studies(OCS) involving 478 and 1402 patients respectively were included.Meta-analysis of RCTs revealed that R-Y reconstruction was associated with a reduced bile reflux(OR 0.04,95%CI:0.01,0.14;P < 0.00 001) and remnant gastritis(OR 0.43,95%CI:0.28,0.66;P = 0.0001),however needing a longer operation time(WMD 40.02,95%CI:13.93,66.11;P = 0.003).Metaanalysis of OCS also revealed R-Y reconstruction had a lower incidence of bile reflux(OR 0.21,95%CI:0.08,0.54;P = 0.001),remnant gastritis(OR 0.18,95%CI:0.11,0.29;P < 0.00 001) and reflux esophagitis(OR 0.48,95%CI:0.26,0.89;P = 0.02).However,this reconstruction method was found to be associated with a longer operation time(WMD 31.30,95%CI:12.99,49.60;P = 0.0008).CONCLUSION:This systematic review point towards some clinical advantages that are rendered by R-Y compared to B-Ⅰ reconstruction post DG.However there is a need for further adequately powered,welldesigned RCTs comparing the same. | Jun-Jie Xiong Kiran Altaf Muhammad A Javed Quentin M Nunes Wei Huang Gang Mai Chun-Lu Tan Rajarshi Mukherjee Robert Sutton Wei-Ming Hu Xu-Bao Liu | 2013 | World Journal of Gastroenterology2013，19，7： | 33 |
| 2 | P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte- endothelial adhesion and promotes neurovascular injury during septic encephalopathy显示文摘 | Huan Wang Ling-Juan Hong Ji-Yun Huang Quan Jiang Rong-Rong Tao Chao Tan Nan-Nan Lu Cheng-Kun Wang Muhammad M Ahmed Ying-Mei Lu Zhi-Rong Liu Wei-Xing Shi En-Yin Lai Christopher S Wilcox Feng Han | 2015 | Cell Research2015，25，6： | 16 |
| 3 | In vitro total phenolics,flavonoids contents and antioxidant activity of essential oil,various organic extracts from the leaves of tropical medicinal plant Tetrastigma from Sabah显示文摘Objective:To detect the in vitro total phenolics,flavonoids contents and antioxidant activity of essential oil,various organic extracts from the leaves of tropical medicinal plant Tetrastigma from Sabah.Methods:The dry powder leaves of Tetrastigma were extracted with different organic solvent such as hexane.ethyl acetate,chloroform,butanol and aqueous methanol.The total phenolic and total flavonoids contents of the essential oil and various organic extracts such as hexane,ethyl acetate,chloroform,butanol and aqueous ethanol were determined by Folin-Ciocalteu method and the assayed antioxidant activity was determined in vitro models such as antioxidant capacity by radical scavenging activity usingα,α-diphenyl-β-picrylhydrazyl (DPPH) method.Results:The total phenolic contents of the essential oil and different extracts as gallic acid equivalents were found to be highest in methanol extract(386.22 mg/g) followed by ethyl acetate(190.89 mg/g).chloroform(175.89 mg/g).hexane(173.44 mg/g).and Imtanol extract (131.72 mg/g) and the phenolic contents not detected in essential oil.The antioxidant capacity of the essential oil and different extracts as ascorbic acid standard was in the order of methanol extract>ethyl acetate extract>chloroform>butanol>hexane extract also the antioxidant activity was not detected in essential oil.Conclusions:The findings show that the extent of antioxidant activity of the essential oil and all extracts are in accordance with the amount of phenolics present in that extract.Leaves of Tetrastigma being rich in phenolics may provide a good source of antioxidant. | M Amzad Hossain Muhammad Dawood Shah Charles Gnanaraj Muhammad Iqbal | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，9： | 9 |
| 4 | Thrombus aspiration during primary percutaneous coronary intervention for acute myocardial infarction:A review of clinical evidence and guidelines显示文摘Acute ST segment elevation myocardial infarction(STEMI) is characterized by complete thrombotic occlusion of a major coronary artery. Early recanalization of the infarct-related artery is most efficiently delivered by primary percutaneous coronary intervention(PPCI),however this does not always restore normal myocardial perfusion,mainly due to distal embolization of the thrombus and microvascular obstruction. Early evidence for manual thrombus aspiration during PPCI was promising and this was once considered an important aspect of the procedure,especially in patients with a high thrombus burden. However,a large body of evidence from recent major randomized controlled trials(notably TASTE and TOTAL) does not support the routine use of manual thrombus aspiration in patients with STEMI undergoing PPCI. | Muhammad Muzaffar Mahmood Jonathan Watt Javed M Ahmed | 2015 | World Journal of Cardiology2015，7，12： | 7 |
| 5 | Prediction of the severity of acute pancreatitis on admission by urinary trypsinogen activation peptide: A meta-analysis显示文摘AIM: To undertake a meta-analysis on the value of urinary trypsinogen activation peptide (uTAP) in predicting severity of acute pancreatitis on admission. METHODS: Major databases including Medline, Embase, Science Citation Index Expanded and the Cochrane Central Register of Controlled Trials in the Cochrane Library were searched to identify all relevant studies from January 1990 to January 2013. Pooled sensitivity, specificity and the diagnostic odds ratios (DORs) with 95%CI were calculated for each study and were compared to other systems/biomarkers if mentioned within the same study. Summary receiver-operating curves were conducted and the area under the curve (AUC) was evaluated. RESULTS: In total, six studies of uTAP with a cut-off value of 35 nmol/L were included in this meta-analysis. Overall, the pooled sensitivity and specificity of uTAP for predicting severity of acute pancreatitis, at time of admission, was 71% and 75%, respectively (AUC = 0.83, DOR = 8.67, 95%CI: 3.70-20.33). When uTAP was compared with plasma C-reactive protein, the pooled sensitivity, specificity, AUC and DOR were 0.64 vs 0.67, 0.77 vs 0.75, 0.82 vs 0.79 and 6.27 vs 6.32, respectively. Similarly, the pooled sensitivity, specificity, AUC and DOR of uTAPvs Acute Physiology and Chronic Health Evaluation Ⅱ within the first 48 h of admission were found to be 0.64 vs 0.69, 0.77 vs 0.61, 0.82 vs 0.73 and 6.27vs 4.61, respectively. CONCLUSION: uTAP has the potential to act as a stratification marker on admission for differentiating disease severity of acute pancreatitis. | Wei Huang Kiran Altaf Tao Jin Jun-Jie Xiong Li Wen Muhammad A Javed Marianne Johnstone Ping Xue Christopher M Halloran Qing Xia | 2013 | World Journal of Gastroenterology2013，19，28： | 7 |
| 6 | Importance of genetic evaluation and testing in pediatric cardiomyopathy显示文摘Pediatric cardiomyopathies are clinically heterogeneous heart muscle disorders that are responsible for significant morbidity and mortality. Phenotypes include hypertrophic cardiomyopathy, dilated cardiomyopathy, restrictive cardiomyopathy, left ventricular noncompaction and arrhythmogenic right ventricular cardiomyopathy. There is substantial evidence for a genetic contribution to pediatric cardiomyopathy. To date, more than 100 genes have been implicated in cardiomyopathy, but comprehensive genetic diagnosis has been problematic because of the large number of genes, the private nature of mutations, and difficulties in interpreting novel rare variants. This review will focus on current knowledge on the genetic etiologies of pediatric cardiomyopathy and their diagnostic relevance in clinical settings. Recent developments in sequencing technologies are greatly impacting the pace of gene discovery and clinical diagnosis. Understanding the genetic basis for pediatric cardiomyopathy and establishing genotypephenotype correlations may help delineate the molecular and cellular events necessary to identify potential novel therapeutic targets for heart muscle dysfunction in children. | Muhammad Tariq Stephanie M Ware | 2014 | World Journal of Cardiology2014，6，11： | 5 |
| 7 | Changes in Nutrient-Homeostasis and Reserves Metabolism During Rice Seed Priming:Consequences for Seedling Emergence and Growth显示文摘In this study influence of different seed priming treatments on the nutrient-homeostasis and reserve metabolism during seedling emergence and growth of rice were determined. Seed priming treatments included pre-germination, hydropriming for 48 h, osmohardening with KCl and CaCl2, ascorbate priming and hardening. All treatments shortened the emergence time and enhanced the energy and index of seedling emergence. Seedlings from primed seeds had greater length, number of roots and fresh and dry mass than control. Among the treatments, CaCl2, ascorbate and KCl proved better in enhancing emergence and seedling growth. Seed priming changed the pattern of N and Ca2+ homeostasis both of the seeds and seedlings, which were associated to enhancing α-amylase activity and reducing sugars content. Positive correlations of seedling attributes with nutrient content suggested that as a result of seed priming, most of N and Ca2+ were partitioned to embryo, which enhanced seedling emergence and subsequent growth of rice seedlings. | Muhammad Farooq Shahzad M A Basra Abdul Wahid Nazir Ahmad | 2010 | Agricultural Sciences in China2010，9，2： | 4 |
| 8 | Surface plasmon polariton at the interface of dielectric and graphene medium using Kerr effect显示文摘We theoretically investigate the control of surface plasmon polariton(SPP) generated at the interface of dielectric and graphene medium under Kerr nonlinearity. The controlled Kerr nonlinear signal of probe light beam in a dielectric medium is used to generate SPPs at the interface of dielectric and graphene medium. The positive, negative absorption, and dispersion properties of SPPs are modified and controlled by the control and Kerr fields. A large amplification(negative absorption) is noted for SPPs under the Kerr nonlinearity. The normal/anomalous slope of dispersion and propagation length of SPPs is modified and controlled with Kerr nonlinearity. This leads to significant variation in slow and fast SPP propagation. The controlled slow and fast SPP propagation may predict significant applications in nano-photonics, optical tweezers, photovoltaic devices, plasmonster, and sensing technology. | Bakhtawar Muhammad Haneef B A Bacha H Khan M Atif | 2018 | Chinese Physics B2018，27，11： | 3 |
| 9 | Seed priming improves early seedling vigor, growth and productivity of spring maize显示文摘Potential of seed priming treatments in improving the performance of early planted maize was evaluated against timely planting. Seeds of maize hybrid FH-810 were soaked in water(hydropriming), Ca Cl2(2.2%, osmopriming), moringa leaf extracts(MLE 3.3%, osmopriming) and salicylic acid(SA, 50 mg L–1, hormonal priming) each for 18 h. Untreated and hydroprimed seeds were taken as control. Seeds primed with SA took less time in emergence and had high vigor in early planted maize. Amongst treatments, hormonal priming, reduced the electrical conductivity, increased the leaf relative and chlorophyll contents followed by osmopriming with Ca Cl2 at seedling stage. Likewise, plant height, grain rows and 1 000-grain weight, grain and biological yield and harvest index were also improved by seed priming; however hormonal priming and osmopriming with MLE were more effective in this regard. Improved yield performance by hormonal priming or osmopriming with MLE in early planting primarily owed to increased leaf area index, crop growth and net assimilation rates, and maintenance of green leaf area at maturity. In conclusion, osmopriming with MLE and hormonal priming with SA were the most economical treatments in improving productivity of early planted spring maize through stimulation of early seedling growth at low temperature. | Hafeez ur Rehman Hassan Iqbal Shahzad M A Basra Irfan Afzal Muhammad Farooq Abdul Wakeel WANG Ning | 2015 | Journal of Integrative Agriculture2015，14，9： | 3 |
| 10 | A framework infrageneric classification of Carex (Cyperaceae) and its organizing principles显示文摘Phylogenetic studies of Carex L.(Cyperaceae)have consistently demonstrated that most subgenera and sections are para-or polyphyletic.Yet,taxonomists continue to use subgenera and sections in Carex classification.Why?The Global Carex Group(GCG)here takes the position that the historical and continued use of subgenera and sections serves to(i)organize our understanding of lineages in Carex,(ii)create an identification mechanism to break the~2000 species of Carex into manageable groups and stimulate its study,and(iii)provide a framework to recognize morphologically diagnosable lineages within Carex.Unfortunately,the current understanding of phylogenetic relationships in Carex is not yet sufficient for a global reclassification of the genus within a Linnean infrageneric(sectional)framework.Rather than leaving Carex classification in its current state,which is misleading and confusing,we here take the intermediate steps of implementing the recently revised subgeneric classification and using a combination of informally named clades and formally named sections to reflect the current state of our knowledge.This hybrid classification framework is presented in an order corresponding to a linear arrangement of the clades on a ladderized phylogeny,largely based on the recent phylogenies published by the GCG.It organizes Carex into six subgenera,which are,in turn,subdivided into 62 formally named Linnean sections plus 49 informal groups.This framework will serve as a roadmap for research on Carex phylogeny,enabling further development of a complete reclassification by presenting relevant morphological and geographical information on clades where possible and standardizing the use of formal sectional names. | Eric H.Roalson Pedro Jiménez-Mejías Andrew L.Hipp Carmen Benítez-Benítez Leo P.Bruederle Kyong-Sook Chung Marcial Escudero Bruce A.Ford Kerry Ford Sebastian Gebauer Berit Gehrke Marlene Hahn Muhammad Qasim Hayat Mathias H.Hoffmann Xiao-Feng Jin Sangtae Kim Isabel Larridon Étienne Léveillé-Bourret Yi-Fei Lu Modesto Luceño Enrique Maguilla Jose IgnacioMárquez-Corro Santiago Martín-Bravo Tomomi Masaki Mónica Míguez Robert F.C.Naczi Anton A.Reznicek Daniel Spalink Julian R.Starr Uzma Tamara Villaverde Marcia J.Waterway Karen L.Wilson and Shu-Ren Zhang | 2021 | Journal of Systematics and Evolution2021，59，4： | 3 |
| 11 | 接受他汀治疗患者新发糖尿病风险:人群为基础的研究显示文摘目的 研究接受HMG-CoA还原酶抑制剂(他汀类药物)治疗的患者的新发糖尿病风险。设计 人群为基础的队列研究,以时间事件分析的方法评估各种他汀类药物应用和新发糖尿病风险的相关性分析。计算危害比(hazard ratios,HR)来确定他汀的种类及剂量与新发糖尿病的关系。 | Aleesa A Caner Tara Gomes Ximena Camacho David N Juurlink Baiju R Shah Muhammad M Mamdani 张秀珍(译) 骆斯慧(译) 翁建平(校) | 2013 | 英国医学杂志中文版2013，16，5： | 2 |
| 12 | 黏籽西瓜、籽瓜和普通西瓜的植物学性状比较分析显示文摘西瓜属于葫芦科的重要水果作物,栽培类型丰富多样,其中黏籽西瓜、籽瓜和普通西瓜是被人类栽培和食用的主要类型,但是这3种类型西瓜的植物学性状差异并没有被系统调查过。针对18份黏籽西瓜、38份籽瓜、174份普通西瓜品种的14个植物学性状进行调查和统计分析,结果显示,供试西瓜品种的植物学性状变异范围大,不同性状在3种类型西瓜之间的差异显著,籽瓜和黏籽西瓜的表型更相似。系统聚类和PCA分析可以将3种类型的西瓜品种基本区分开来,籽瓜介于黏籽西瓜和普通西瓜之间。该研究结果有助于充分了解和利用西瓜种质资源,能够为培育理想株型和优质的西瓜新品种提供科学依据。 | 袁平丽 龚成胜 何楠 刁卫楠 Muhammad Jawad Umer 朱红菊 杨东东 Muhammad Anees 路绪强 Kaseb M O 赵胜杰 刘文革 | 2021 | 中国瓜菜2021，34，9： | 2 |
| 13 | Survival and outcomes for co-infection of chronic hepatitis C with and without cirrhosis and COVID-19: A multicenter retrospective study显示文摘BACKGROUND Chronic liver disease,particularly cirrhosis,is associated with worse outcomes in patients infected with coronavirus disease 2019(COVID-19).AIM To assess outcomes of COVID-19 infection among patients with pre-existing hepatitis C with or without liver cirrhosis.METHODS This multicenter,retrospective cohort study included all cases of confirmed coinfection of severe acute respiratory syndrome coronavirus 2 and chronic hepatitis C with or without liver cirrhosis who were admitted to six hospitals(Al-Sahel Hospital,Al-Matareya Hospital,Al-Ahrar Hospital,Ahmed Maher Teaching Hospital,Al-Gomhoreya Hospital,and the National Hepatology and Tropical Medicine Research Institute)affiliated with the General Organization for Teaching Hospitals and Institutes in Egypt.Patients were recruited from May 1,2020,to July 31,2020.Demographic,laboratory,imaging features,and outcomes were collected.Multivariate regression analysis was performed to detect factors affecting mortality.RESULTS This retrospective cohort study included 125 patients with chronic hepatitis C and COVID-19 co-infection,of which 64(51.20%)had liver cirrhosis and 40(32.00%)died.Fever,cough,dyspnea,and fatigue were the most frequent symptoms in patients with liver cirrhosis.Cough,sore throat,fatigue,myalgia,and diarrhea were significantly more common in patients with liver cirrhosis than in noncirrhotic patients.There was no difference between patients with and without cirrhosis regarding comorbidities.Fifteen patients(23.40%)with liver cirrhosis presented with hepatic encephalopathy.Patients with liver cirrhosis were more likely than non-cirrhotic patients to have combined ground-glass opacities and consolidations in CT chest scans:28(43.75%)vs 4(6.55%),respectively(P value<0.001).These patients also were more likely to have severe COVID-19 infection,compared to patients without liver cirrhosis:29(45.31%)vs 11(18.04%),respectively(P value<0.003).Mortality was higher in patients with liver cirrhosis,compared to those with no cirrhosis:33(51.56%)vs 9(14.75%),respectively(P value<0.001).All patients in Child-Pugh class A recovered and were discharged.Cirrhotic mortality occurred among decompensated patients only.A multivariate regression analysis revealed the following independent factors affecting mortality:Male gender(OR 7.17,95%CI:2.19–23.51;P value=0.001),diabetes mellitus(OR 4.03,95%CI:1.49–10.91;P value=0.006),and liver cirrhosis(OR 1.103,95%CI:1.037–1.282;P value<0.0001).We found no differences in liver function,COVID-19 disease severity,or outcomes between patients who previously received direct-acting antiviral therapy(and achieved sustained virological response)and patients who did not receive this therapy.CONCLUSION Patients with liver cirrhosis are susceptible to higher severity and mortality if infected with COVID-19.Male gender,diabetes mellitus,and liver cirrhosis are independent factors associated with increased mortality risk. | Shimaa Afify Basem Eysa Fatma Abdel Hamid Omnia M Abo-Elazm Mohamed A Edris Rabab Maher Ahmed Abdelhalim Muhammad Mostafa Abdel Ghaffar Dalia A Omran Hend Ibrahim Shousha | 2021 | World Journal of Gastroenterology2021，27，42： | 2 |
| 14 | 对应用选择性环氧酶2抑制剂或传统非甾体类抗炎药物老年患者上消化道出血的观察研究显示文摘目的 对应用选择性环氧酶2(COX 2)抑制剂和非选择性的非甾体类抗炎药(NSAIDs)的老年患者上消化道出血的比率进行比较。 设计 观察性队列研究。 设置 利用来自加拿大安大略2000年4月17日~2001年3月31日的官方数据,以确认基于人群的、初次使用NSAID的队列患者。 对象 年龄≥66岁,开始服用非选择性NSAIDs(n=5391)、双氯芬酸(diclofenac)加米索前列醇(misoprostol)(n=5087)、罗非昔布(rofecoxib)(n=14 583)或塞来昔布(celecoxib)(n=18 908),以及随机选择的没有服用NSAIDs的对照组(n=100 000)。 衡量结局的主要指标 每个药物组因上消化道出血入院的比值比(经过调整潜在的混杂因子)。 结果 与对照组相比,多变量模型表明,在服用非选择性NSAIDs(调整比值比为4.0,95%,可信区间为2.3~6.9,)、双氯芬酸加米索前列醇(3.0,1.7~5.6)以及罗非昔布(1.9,1.3~2.8)时,上消化道出血的短期危险性是增加的,而塞来昔布并没有增加(1.0,0.7~1.6)。与塞来昔布相比,非选择性的NSAIDs(4.4,2.3~8.5)、双氯芬酸加 米索前列醇(3.2,1.6—6.5)以及罗非昔布(1.9,1.2~2.8)的上消化道出血危险性显著增加。与罗非昔布相比,非选择性NSAIDs的上消化道出血危险性显著增加(1.9,1.0~3.5)。 结论 选择性COX | Muhammad Mamdani Paula A Rochon David N Juurlink Alex Kopp Geoffrey M Anderson Gary Naglie Peter C Austin Andreas Laupacis 邓瑞雪 | 2003 | 英国医学杂志中文版2003，6，3： | 2 |
| 15 | Structural, electronic, and optical properties of ZnO_(1-x)Se_x alloys using first-principles calculations显示文摘The structural, electronic, and optical properties of binary ZnO, ZnSe compounds, and their ternary ZnO 1-x Se x alloys are computed using the accurate full potential linearized augmented plane wave plus local orbital (FP-LAPW + lo) method in the rocksalt (B1) and zincblende (B3) crystallographic phases. The electronic band structures, fundamental energy band gaps, and densities of states for ZnO 1-x Se x are evaluated in the range 0 ≤ x ≤ 1 using Wu-Cohen (WC) generalized gradient approximation (GGA) for the exchange-correlation potential. Our calculated results of lattice parameters and bulk modulus reveal a nonlinear variation for pseudo-binary and their ternary alloys in both phases and show a considerable deviation from Vegard's law. It is observed that the predicted lattice parameter and bulk modulus are in good agreement with the available experimental and theoretical data. We establish that the composition dependence of band gap is semi-metallic in B1 phase, while a direct band gap is observed in B3 phase. The calculated density of states is described by taking into account the contribution of Zn 3d, O2p, and Se 4s, and the optical properties are studied in terms of dielectric functions, refractive index, reflectivity, and energy loss function for the B3 phase and are compared with the available experimental data. | Muhammad Rashid Fayyaz Hussain Muhammad Imran S A Ahmad N A Noor M U Sohaib S M Alay-e-Abbas | 2013 | Chinese Physics B2013，22，8： | 2 |
| 16 | Information Regarding Agronomic Practices and Plant Protection Measures Obtained by the Farmers through Electronic Media显示文摘 | Khan G A Muhammad S Ch K M | 2013 | Journal of Animal and Plant Sciences2013，23，2： | 1 |
| 17 | Chemical profiling and standardization of Lepidium meyenii(Maca)by reversed phase high performance liquid chromatography显示文摘 | Ganzera M Zhao J Muhammad I | 2002 | Chemical and Pharmaceutical Bulletin-Tokyo2002，50，7： | 1 |
| 18 | Therapeutic implications of cancers tem cell显示文摘 | Muhammad AH Becker M Max W | 2004 | Curr Opin Genet Dev2004，14，1： | 1 |
| 19 | A novel FP- GA implementation of AES-128 using reduced res- idue of prime numbe based S-Box 显示文摘 | Muhammad H Rais Syed M Qasim | 2009 | IJCSNS International Journal of Computer Science and Net- work Security2009，9，9： | 1 |
| 20 | Common cause failure analysis of PWR containment spray system by GO-FLOW methodology显示文摘 | Muhammad H Hidekazu Y Takeshi M | 2013 | Nuclear Engineering and Design2013，262，9： | 1 |
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