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| 1 | Ever-increasing diversity of drug-induced pancreatitis显示文摘With over 100000 hospital admissions per annum,acute pancreatitis remains the leading gastrointestinal cause of hospitalization in the United States and has farreaching impact well beyond.It has become increasingly recognized that druginduced pancreatitis(DIP),despite accounting for less than 3%of all cases,represents an important and growing though often inconspicuous cause of acute pancreatitis.Nevertheless,knowledge of DIP is often curtailed by the limited availability of evidence needed to implicate given agents,especially for nonprescription medications.Indeed,the majority of available data is derived from case reports,case series,or case control studies.Furthermore,the mechanism of injury and causality for many of these drugs remain elusive as a definitive correlation is generally not established(<10%of cases).Several classification systems have been proposed,but no single system has been widely adopted,and periodic updates are required in light of ongoing pharmacologic expansion.Moreover,infrequently prescribed medications or those available over-thecounter(including herbal and other alternative remedies)are often overlooked as a potential culprit of acute pancreatitis.Herein,we review the ever-increasing diversity of DIP and the potential mechanisms of injury with the goal of raising awareness regarding the nature and magnitude of this entity.We believe this manuscript will aid in increasing both primary and secondary prevention of DIP,thus ultimately facilitating more expedient diagnosis and a decrease in DIPrelated morbidity. | Simcha Weissman Muhammad Aziz Ryan B Perumpail Tej I Mehta Rutwik Patel James H Tabibian | 2020 | World Journal of Gastroenterology2020，26，22： | 8 |
| 2 | Gut microbiota profile in healthy Indonesians显示文摘BACKGROUND Recently, gut microbiota has been associated with various diseases other than intestinal disease. Thus, there has been rapid growth in the study of gut microbiota. Considering the numerous factors influencing gut microbiota such as age, diet, etc., area-based research is required. Indonesia has numerous different tribes and each of these tribes have different lifestyles. Hence, it is expected that each tribe has a specific gut microbiota. A deeper insight into the composition of gut microbiota can be used to determine the condition of gut microbiota in Indonesians and to consider which treatment may be suitable and effective to improve health status.AIM To investigate the gut microbiota of Indonesian subjects represented by Javanese and Balinese tribes by analyzing fecal samples.METHODS Fecal samples were collected from a total of 80 individuals with 20 in each of the young groups ranging from 25-45 years and the elderly group aged 70 years or more from two different regions, Yogyakarta and Bali. Fecal sample collection was performed at the end of the assessment period(day 14 ± 1 d) during which time the subjects were not allowed to consume probiotic or antibiotic products.The quantification of various Clostridium subgroups, Lactobacillus subgroups,Enterococcus, Streptococcus, Staphylococcus, Bacteroides fragilis group and Prevotella,Bifidobacterium and Atopobium cluster, Enterobacteriaceae and Pseudomonas was performed using the Yakult intestinal flora-scan(YIF-SCAN).RESULTS The bacterial population in younger subjects' feces was higher than that in the elderly population, with a total of approximately 10.0 – 10.6 log10 bacterial cells/g feces. The most abundant bacteria in all groups were Clostridium, followed by Prevotella, Atopobium, Bifidobacterium and Bacteroides. In the elderly, an increase in Enterobacteriaceae, Coliform and Escherichia coli was found. In terms of bacterial counts in Yogyakarta, total bacteria, Clostridium coccoides(C. coccoides) group,Bifidobacterium, Prevotella, Lactobacillus plantarum subgroup, and Streptococcus were significantly higher(P < 0.05) in younger than elderly subjects, while the Lactobacillus gasseri subgroup, Lactobacillus casei subgroup, and Lactobacillus reuteri subgroup counts were significantly lower(P < 0.05) in younger subjects. In Balinese subjects, total bacteria, C. coccoides group, Clostridium leptum subgroup,Bacteroides fragilis group, and Prevotella were significantly higher(P < 0.05) in younger compared to elderly individuals, while the Lactobacillus ruminis subgroup, and Enterobacteriaceae were significantly lower(P < 0.05) in younger subjects. The results also revealed that, besides the C. coccoides group and Clostridium leptum group being the most abundant gut microbiota in both Yogyakarta and Balinese people, the latter was indicated by a higher Clostridium perfringens count, which was almost 10 times that of Yogyakarta subjects. This may be a response to different lifestyles in the different tribes; however, this phenomenon requires further extensive study.CONCLUSION Bacterial populations were higher in younger than in elderly subjects. Most abundant bacterial groups were Clostridium, Prevotella, Atopobium, Bifidobacterium,and Bacteroides. The level of Clostridium perfringens in Yogyakarta subjects was lower than that in Balinese subjects. | Endang Sutriswati Rahayu Tyas Utami Mariyatun Mariyatun Pratama Nur Hasan Rafli Zulfa Kamil Ryan Haryo Setyawan Fathyah Hanum Pamungkaningtyas IskANDar Azmy Harahap Devin Varian Wiryohanjoyo Putrika Citta Pramesi Muhammad Nur Cahyanto I Nengah Sujaya Mohammad Juffrie | 2019 | World Journal of Gastroenterology2019，25，12： | 6 |
| 3 | 辽宁省慢生根瘤菌的系统发育多样性 | 张艳华 王惠 王岩 Muhammad I 黄玉茜 韩梅 杨劲峰 韩晓日 白洪志 | 2016 | 江苏农业科学2016，44，7： | 2 |
| 4 | Effect of Nitric Oxide on Alleviating Cadmium Toxicity in Rice (Oryza sativa L.)显示文摘Nitric oxide (NO) is a gaseous signaling molecule in plants that plays a key role in mediating a wide range of physiological processes and responses to biotic and abiotic stresses. The present study was conducted to investigate the effects of the exogenous application of sodium nitroprusside (SNP), an NO donor, on cadmium (Cd)-induced oxidative stress and Cd uptake in rice plants. Rice plants were exposed to Cd stress (0.2 mmol L^(-1) CdCl_2) and different concentrations of SNP (0.05, 0.1, 0.2, and 0.4 mmol L^(-1)). A SNP concentration of 0.1 mmol L^(-1) (SNP10) significantly reduced the Cd-induced decrease in shoot and root dry weights and leaf chlorophyll concentrations. The addition of NO also reduced the malondialdehyde (MDA), hydrogen peroxide (H_2O_2) and ascorbic acid (ASA) concentrations. However, the reduction in glutathione (GSH) concentration was inhibited by NO treatment. Moreover, NO prevented the Cd-induced increase in antioxidative enzyme activity. The amount of Cd accumulation in rice plants was also influenced by the addition of NO. The NO supplied by the SNP enhanced the Cd tolerance of the rice by increasing the Cd uptake by the roots and decreasing the Cd accumulation by the shoots. However, the application of potassium ferrocyanide (Cd+Fe) or sodium nitrate and nitrite (Cd+N) (without NO release), did not exhibit the effects of the SNP. Furthermore, the effects of the SNP were reversed by the addition of hemoglobin (an NO scavenger). Our results suggested that exogenous NO was involved in the resistance of rice to Cd-toxicity. | ZHAO Xiu-feng CHEN Lin Muhammad I A Rehmani WANG Qiang-sheng WANG Shao-hua HOU Peng-fu LI Gang-hua DING Yan-feng | 2013 | Journal of Integrative Agriculture2013，12，9： | 2 |
| 5 | Structure-activityrelationships of quassinoids for eukaryotic protein synthesis显示文摘 | Fukamiya N Lee K H Muhammad I | 2005 | Cancer Lett2005，220，1： | 1 |
| 6 | Constitu- ents of Lepidium meyenii 'maca' 显示文摘 | MUHAMMAD I ZHAO JP DUNBAE DC | 2002 | Phytochemistry2002，59，1： | 1 |
| 7 | Chemical profiling and standardization of Lepidium meyenii(Maca)by reversed phase high performance liquid chromatography显示文摘 | Ganzera M Zhao J Muhammad I | 2002 | Chemical and Pharmaceutical Bulletin-Tokyo2002，50，7： | 1 |
| 8 | Data flow analysis of UML action semantics for executable models显示文摘 | Tabinda W Muhammad Z Zafar I | 2008 | Lecture Notes in Computer Science2008，5095，1： | 1 |
| 9 | 显示文摘 | Muhammad I Bo-Kyung K | 2010 | Polymer Degradation and Sta bilit y2010，95，9： | 1 |
| 10 | Constituents of Lepidium meyenii ' maca' 显示文摘 | Muhammad I Zhao J Dunbar DC | 2002 | Phytochemistry2002，59，1： | 1 |
| 11 | A New Iterative Method for Solving Absolute Value Equations显示文摘 | MUHAMMAD A N JAVED I SANJAY K | 2011 | International Journal of the Physical Sciences2011，6，7： | 1 |
| 12 | New alkamides from maca ( Lepiclium meyenii ) 显示文摘 | Zhao J Muhammad I Dunbar DC | 2005 | Journal of agricultural and Food Chemistry2005，53，3： | 1 |
| 13 | Antimalarial, cytotoxic, and antifungal alkaloids from Duguetia hadrantha 显示文摘 | Muhammad I Dunbar D C Takamatsu S | 2001 | J Nat Prod2001，64，5： | 1 |
| 14 | Laparoscopic versus poen repair of incisional/ventral hernia:a meta-analysis显示文摘 | Muhammad SS Syed A Bokhari I | 2009 | Am J Surg2009，197，1： | 1 |
| 15 | On an Iterative Method for Solving Absolute Value Equations 显示文摘 | MUHAMMAD A N JAVED I KHALIDA I N | 2012 | Optim Lett2012，6，5： | 1 |
| 16 | Needle clinical predic- tors of EMG -confirmed cervical and lumbosacral radiculopathy显示文摘 | Ali Hassan BH Muhammad I Bhojo K | 2013 | Can J Neurol Sci2013，40，： | 1 |
| 17 | Furoquinoline al- kaloids from Teclea nobilis 显示文摘 | A1 - Rehaily A J Ahmad M S Muhammad I | 2003 | Phytochemistry2003，64，8： | 1 |
| 18 | Effect of nickel loading on hydrogenproduction and chemical oxygen demand(COD)destruction from glucose oxidation and gasification insupercritical water显示文摘 | Youssef Emhemmed A Chowdhury Muhammad B I Nakhla G | 2010 | International Journal of HydrogenEnergy2010，35，10： | 1 |
| 19 | Task assignment using a problem-space genetic algorithm显示文摘 | AHMAD I MUHAMMAD K DHODHI | 2006 | Concurrency: Practice and Expedence2006，7，5： | 1 |
| 20 | Solid state bioconversion of oil palm empty fruit bunches for cellulase enzyme production using a rotary drum bioreactor显示文摘 | I Alam M Z Mahmat M E Muhammad N | 2007 | Biochemical Engineering Journal2007，46，： | 1 |
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