|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement显示文摘 | M Dominici K Le Blanc I Mueller I Slaper-Cortenbach Fc Marini Ds Krause Rj Deans A Keating Dj Prockop Em Horwitz | 2006 | Cytotherapy2006，，4： | 11 |
| 2 | Increased liver stiffness in alcoholic liver disease:Differentiating fibrosis from steatohepatitis显示文摘AIM:To test if inflammation also interferes with liver stiffness (LS) assessment in alcoholic liver disease (ALD) and to provide a clinical algorithm for reliable fibrosis assessment in ALD by FibroScan (FS).METHODS:We first performed sequential LS analysis before and after normalization of serum transaminases in a learning cohort of 50 patients with ALD admitted for alcohol detoxification. LS decreased in almost all patients within a mean observation interval of 5.3 d. Six patients (12%) would have been misdiagnosed with F3and F4 fibrosis but LS decreased below critical cut-off values of 8 and 12.5 kPa after normalization of trans-aminases. RESULTS:Of the serum transaminases,the decrease in LS correlated best with the decrease in glutamic oxaloacetic transaminase (GOT). No significant chang-es in LS were observed below GOT levels of 100 U/L. After establishing the association between LS and GOT levels,we applied the rule of GOT < 100 U/L for reliable LS assessment in a second validation cohort of 101 patients with histologically confi rmed ALD. By ex-cluding those patients with GOT > 100 U/L at the time of LS assessment from this cohort,the area under the receiver operating characteristic (AUROC) for cirrhosis detection by FS improved from 0.921 to 0.945 while specificity increased from 80% to 90% at a sensitivity of 96%. A similar AUROC could be obtained for lower F3 fibrosis stage if LS measurements were restricted to patients with GOT < 50 U/L. Histological grading of inflammation did not further improve the diagnostic accuracy of LS.CONCLUSION:Coexisting steatohepatitis markedly increases LS in patients with ALD independent of fibrosis stage. Postponing cirrhosis assessment by FS during alcohol withdrawal until GOT decreases to < 100 U/mL signif icantly improves the diagnostic accuracy. | Sebastian Mueller Gunda Millonig Lucie Sarovska Stefanie Friedrich Frank M Reimann Maria Pritsch Silke Eisele Felix Stickel Thomas Longerich Peter Schirmacher Helmut Karl Seitz | 2010 | World Journal of Gastroenterology2010，16，8： | 10 |
| 3 | Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement显示文摘 | M Dominici K Le Blanc I Mueller I Slaper-Cortenbach Fc Marini Ds Krause Rj Deans A Keating Dj Prockop Em Horwitz | 2006 | Cytotherapy2006，，4： | 9 |
| 4 | Acute pancreatitis in aging animals:Loss of pancreatitis-associated protein protection?显示文摘AIM:To investigate the effect of age on severity of acute pancreatitis(AP) using biochemical markers,histology and expression of the protective pancreatitisassociated proteins(PAPs).METHODS:AP was induced via intraductal injection of 4% sodium taurocholate in young and old rats.Sera and pancreata were assayed at 24 h for the parameters listed above;we also employed a novel molecular technique to assess bacterial infiltration using polymerase chain reaction to measure bacterial genomic ribosomal RNA.RESULTS:At 24 h after induction of AP,the pancreata of older animals had less edema(mean ± SE histologic score of young vs old:3.11 ± 0.16 vs 2.50 ±-0.11,P < 0.05),decreased local inflammatory response(histologic score of stromal infiltrate:3.11 ± 0.27 vs 2.00 ± 0.17,P < 0.05) and increased bacterial infiltration(174% ± 52% increase from sham vs 377% ± 4%,P < 0.05).A decreased expression of PAP1 and PAP2 was demonstrated by Western blotting analysis and immunohistochemical staining.There were no differences in serum amylase and lipase activity,or tissue myeloperoxidase or monocyte chemotactic protein-1 levels.However,in the most-aged group,serum C-reactive protein levels were higher(young vs old:0.249 ± 0.04 mg/dL vs 2.45 ± 0.68 mg/dL,P < 0.05).CONCLUSION:In older animals,there is depressed PAP expression related to a blunted inflammatory response in AP which is associated with worsened bacterial infiltration and higher C-reactive protein level;this may explain the more aggressive clinical course. | Sophia Fu Albert Stanek Cathy M Mueller Nefertti A Brown Chongmin Huan Martin H Bluth Michael E Zenilman | 2012 | World Journal of Gastroenterology2012，18，26： | 5 |
| 5 | Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement显示文摘 | EM Horwitz K Le Blanc M Dominici I Mueller I Slaper-Cortenbach FC Marini RJ Deans DS Krause A Keating | 2005 | Cytotherapy2005，，5： | 2 |
| 6 | Experimental and numerical studies of shock wave focusing in water显示文摘 | Sommerfeld M Mueller M | 1988 | Experiments in Fluids1988，6，： | 2 |
| 7 | Magnetic and crystallographic properties of several C1b type Heusler compounds 显示文摘 | Helmholdt R B de Groot R A Mueller F M | 1984 | J Magn Magn Mater1984，43，： | 2 |
| 8 | Simvastatin versus ezetimibe:pleiotropic and lipid-lowering effects on endothelial function in humans显示文摘 | Landmesser U Bahlmann F Mueller M | 2005 | Circulation2005，111，18： | 1 |
| 9 | Voltage sags in industrial systems显示文摘 | MCGRANAGHAN M F MUELLER D R SAMOTYJ M J | 1993 | IEEE Trans Industry Applications1993，29，2： | 1 |
| 10 | Direct drive wave energy converters 显示文摘 | BAKER N J MUELLER M A | 2001 | Rev Energ Ren : Power Engineering2001，，： | 1 |
| 11 | Inflammation and long-term mortality after ono-ST elevation acute coronary syndrome treated with a very early invasive strategy in 1042 consecutive patients显示文摘 | Mueller C Buettner H J Hodgson J M | 2002 | Circula-tion2002，105，： | 1 |
| 12 | Copeptin and risk stratification in patients With acute dyspnea 显示文摘 | Potocki M Breidthardt T Mueller A | 2010 | Critical Care2010，14，6： | 1 |
| 13 | Anti-angiogenic treatment of endometriosis : biochemical aspects 显示文摘 | Taylor R N Mueller M D | 2004 | Gynecol Obstet Invest2004，57，1： | 1 |
| 14 | Macrofungal diversity of a temperate oak forest:a test of species richness estimators显示文摘 | Schmit P J Murphy J F Mueller G M | | 0，，07： | 1 |
| 15 | Affect and creativity at work显示文摘 | Amabile T M Barsade S G Mueller J S and Staw B M | 2005 | Administrative Science Quarter- ly2005，50，3： | 1 |
| 16 | Simvastatin versus ezetimibe: pleiotropic and lipid-lowering effects on endothelial function in humans 显示文摘 | Landmesser U Bahhnann F Mueller M | 2005 | Circulation2005，111，18： | 1 |
| 17 | A novel family of mammalian taste receptors显示文摘 | Adler E Hoon M A Mueller K L | 2000 | Cell2000，100，： | 1 |
| 18 | Tricuspid valve involvement in combined mitrial and aortic valve surgery显示文摘 | Mueller X M Tevaearai H T Stumpe F | 2001 | J Cardiovasc Surg2001，42，4： | 1 |
| 19 | Weak independent association signals between IDE poly- morphisms, Alzheimer's disease and cognitive measures显示文摘 | Mueller JC Riemenschneider M Sehoeper-Wendels A | 2007 | Neurobiol Aging2007，28，5： | 1 |
| 20 | Effect of Metatarsal Pad Placement on Plantar Pressure in People with Diabetes Mellitus and Peripheral Neuropathy显示文摘 | Hastings M K Mueller M J Pilgram T K | 2007 | Foot Ankle Int2007，28，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员