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| 1 | Mouse embryos cloned from brain tumors显示文摘Cancer cells escape from growth cont rol by accumulating genetic and epig enetic alterations.In rare instances,epigenetic changes alone are oncogenic.Furthermore,a gents that modify DNA methylation or chromatin structure can restore a normal phenotype to cells harboring oncogenic mutations.How ever,it is unclear to what extent epi genetic reprogramming can reverse o ncogenesis.Using somatic nuclear transfer,we show that medul loblastomas arising in Ptc1+/-mice can direct preimplantation develop ment.Additionally,blastocysts derived from medullobl astoma nuclei form postimplantatio n embryos with typical cell layers.T hus,tumor cells can be epigenetically reprogrammed into n ormal cell types.This approach coul d lead to a general strategy for assessing genetic and epigenetic contributions to tumorigenesis. | Li L Connelly MC Wetmore C Curran T Morgan JI | 2003 | 癌症2003，22，7： | 11 |
| 2 | Archaeological records of Dadiwan in the past 60 ka and the origin of millet agriculture显示文摘This paper reports the recent excavation of Unit Dadiwan06 at the Dadiwan site in Qin’an County, Gansu.A 65 ka chronological framework is established for Dadiwan06 on the basis of absolute dating (AMS 14C and OSL), stratigraphy, climate change events and archaeology.Artifact distributions reveal patterns of human behavioral variation and adaptation over the past 60 ka, from primitive hunting and gathering to advanced hunting and gathering, to primitive Neolithic agriculture, and finally to advanced Neolithic agriculture. | ZHANG DongJu CHEN FaHu BETTINGER R L BARTON L JI DuXue MORGAN C WANG Hui CHENG XiaoZhong DONG GuangHui GUILDERSON T P ZHAO Hui | 2010 | Chinese Science Bulletin2010，55，16： | 6 |
| 3 | Proto-oncogene transcription factors and pilepsy显示文摘 | Morgan JI Gurran T | 1991 | Trends Pharmacol Sci1991，12，9： | 1 |
| 4 | Stimulus transcription coupling in neurons:role of cellular immediate-early genes显示文摘 | | 1989 | TINS,1989,12(11):459-4621989，12，11： | 1 |
| 5 | Role of ion flux in the control of c -fos expression显示文摘 | Curran T | 1996 | Nature1996，322，6079： | 1 |
| 6 | The susceptibility of the retina to photochemical damage from visible light 显示文摘 | Hunter JJ Morgan JI Merigan WH | 2012 | Prog Retin Eye Res2012，31，1： | 1 |
| 7 | Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes los and jun显示文摘 | Morgan JI Curran T | 1991 | Annu Rev Neurosci1991，14，： | 1 |
| 8 | Mapping pattern of c --los expression in the central nervous system after seizure显示文摘 | Morgan JI Cohen DR Hempstead JL | 1987 | Sci- ence1987，237，4811： | 1 |
| 9 | Catalytic deoxygenation of triglycerides to hydrocarbons over supported nickel catalysts显示文摘 | Tonya Morgan Eduardo Santillan-Jimenez Anne E. Harman-Ware Yaying Ji Daniel Grubb Mark Crocker | 2012 | Chemical Engineering Journal2012，，： | 1 |
| 10 | Regulation of proenkephalin by Fos and Jun 显示文摘 | | 1989 | Science,1989,246(4937):1622-16251989，246，4937： | 1 |
| 11 | Immediate-early genes:ten years on显示文摘 | Morgan JI Curran T | 1995 | Trends Neure Sci1995，18，2： | 1 |
| 12 | Bol-xS and Bad potentiate the death suppressing activities of Bcl-xL,Bcl-2,and A1 in yeast显示文摘 | Tao W Kurschner C Morgan JI | 1998 | J Biol Chem1998，273，23： | 1 |
| 13 | Immediate-early genes: ten years on显示文摘 | Morgan JI Cun'an T | 1995 | Trends Neuro Sci1995，18，2： | 1 |
| 14 | The structure and proteolytic processing of Cblnl complexes显示文摘 | Bao D Pang Z Morgan JI | 2005 | J Neurochem2005，95，： | 1 |
| 15 | Protooncogen transcription factor and epilepsy显示文摘 | Morgan JI Currant T | 1991 | TIPS1991，12，： | 1 |
| 16 | Role of ion flux in the control of c-fos expression显示文摘 | Morgan JI Curran T | 1986 | Nature1986，322，6079： | 1 |
| 17 | Mapping patterns of c-fos expression in the central nervous system after seizure显示文摘 | Morgan JI Cohen DR Hempstead JL | 1987 | Science1987，237，： | 1 |
| 18 | Stimulus-transcription coupling in the nervous system involvement of the inducible proto-oncogene fos and jun 显示文摘 | Morgan JI Curran T | 1991 | Annu Rev Neurosci1991，14，： | 1 |
| 19 | Fos: an immedi- ate-early transcription factor in neurons 显示文摘 | Curran T Morgan JI | 1995 | J Neurobiol1995，26，： | 1 |
| 20 | Bio-oil upgrading over platinum catalysts using in situ generated hydrogen 显示文摘 | Fisk C A Morgan T Ji Y | 2009 | Applied Catalysis A: General2009，358，2： | 1 |
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