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7篇 您的检索式:作者名="Connelly MC"
    题名 作者 年代 出处 被引量
1Mouse embryos cloned from brain tumors显示文摘Cancer cells escape from growth cont rol by accumulating genetic and epig enetic alterations.In rare instances,epigenetic changes alone are oncogenic.Furthermore,a gents that modify DNA methylation or chromatin structure can restore a normal phenotype to cells harboring oncogenic mutations.How ever,it is unclear to what extent epi genetic reprogramming can reverse o ncogenesis.Using somatic nuclear transfer,we show that medul loblastomas arising in Ptc1+/-mice can direct preimplantation develop ment.Additionally,blastocysts derived from medullobl astoma nuclei form postimplantatio n embryos with typical cell layers.T hus,tumor cells can be epigenetically reprogrammed into n ormal cell types.This approach coul d lead to a general strategy for assessing genetic and epigenetic contributions to tumorigenesis.Li L Connelly MC Wetmore C Curran T Morgan JI 2003癌症2003,22,7:11
2MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs 显示文摘Schuetz JD Connelly MC Sun D 1999Nat Med1999,5,9:1
3Standardization of absolute CD4_ lymphocyte counts across laboratories:an evaluation of the Ortho Cytoron absolute flow cytometry system on normal donors显示文摘Connelly MC Knight M Giorgi JV 1995Cytometry1995,22,:1
4Scavenger receptor BI (SR-BI) clustered on microvillar extensions suggests that this p lasma membrane domain is a way station for cholesterol trafficking between cells and highdensity lipop rotein显示文摘Peng Y Akmentin W Connelly MA Lund-Katz S Phillips MC Williams DL 2004Mol Biol Cell2004,15,:1
5Metabolic diversity and antiviral activities of acyclic nucleoside phosphonates显示文摘Aduma P Connelly MC Srinivas RV 1995Mol Phrmacol1995,47,4:1
6Metabolic diversity and antiviral activities of acyclic nucleoside phosphonates显示文摘Aduma P Connelly MC Srinivas RV 1995Mol Pharmacal1995,47,4:1
7MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs 显示文摘Schuetz JD Connelly MC Sun D 1999Nat Med1999,5,:1
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