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| 1 | Circulating miR-483-3p and miR-21 is highly expressed in plasma of pancreaticcancer显示文摘 | Makoto Abue Misa Yokoyama Rie Shibuya Keiichi Tamai Kazunori Yamaguchi Ikuro Sato Nobuyuki Tanaka Shin Hamada Tooru Shimosegawa Kazuo Sugamura Kennichi Satoh | 2015 | International Journal of Oncology2015，，2： | 3 |
| 2 | Gene expression of CCL8 and CXCL10 in peripheral blood leukocytes during early pregnancy in cows显示文摘Background: The aim of the present study was to evaluate CCL8 and CXCL10 expression and its regulatory mechanism in peripheral blood leukocytes(PBLs) at the time of maternal recognition in cows. Blood samples were collected on 14, 15, 16, 17 and 18 d after artificial insemination(AI). Based on the day of return of estrus, cows were divided into three groups, pregnant(n = 5), early embryonic mortality(EEM; n = 5) and late embryonic mortality(LEM; n = 5). The gene expression levels in PBLs were assessed with quantitative real-time reverse transcription PCR.Results: The expression of CCL8 and CXCL10 mRNA in PBLs gradually increased from 14 to 18 d of pregnant cows and significant differences were observed on 18 d(P < 0.05), whereas no significant changes were observed both in EEM and LEM cows. Interferon-stimulated protein 15 k Da(ISG15), myxovirus-resistance gene(MX) 1 and MX2 mRNA expression in PBLs increased from 14 to 18 d which was significant on 18 d of pregnant cows as well as in LEM cows(P < 0.05), but no changes were observed in EEM cows. To determine whether the expression of CCL8 and CXCL10 in PBLs was regulated by pregnancy-related substances or not, expression level was assessed after exposure to interferon-τ(IFNT) and CCL16. Monocytes, granulocytes and lymphocytes were obtained using density-gradient centrifugation and flow cytometry. The addition of IFNT(100 ng/mL) and CCL16(100 ng/mL) to cultured PBLs increased the expression of CCL8 and CXCL10 mRNA(P < 0.05). The expression of ISG15, MX1 and MX2 mRNA in PBLs was also stimulated by IFNT and CCL16(P < 0.05).Conclusions: The expression of CCL8 and CXCL10 genes increased in PBLs during early pregnancy. Since IFNT stimulated CCL8 and CXCL10 expression in cultured PBLs, the increase of CCL8 and CXCL10 might be pregnancy-dependent events.The expression of both CCL8 and CXCL10 in PBLs was stimulated by CCL16 as wel as IFNT, suggesting a chemokine interaction that at least includes CCL8, CXCL10 and CCL16, and may play a role in regulating maternal recognition in cows. | Ryosuke Sakumoto Kosuke Iga Ken-Go Hayashi Shiori Fujii Hiroko Kanahara Misa Hosoe Tadashi Furusawa | 2018 | Journal of Animal Science and Biotechnology2018，9，4： | 3 |
| 3 | Incidence and Prognostic Value of Early Repolarization Pattern in the 12-Lead Electrocardiogram显示文摘 | Daisuke Haruta Kiyotaka Matsuo Akira Tsuneto Shinichiro Ichimaru Ayumi Hida Nobuko Sera Misa Imaizumi Eiji Nakashima Koji Maemura Masazumi Akahoshi | 2011 | Circulation2011，，25： | 2 |
| 4 | CD74 Is a Novel Prognostic Factor for Patients with Pancreatic Cancer Receiving Multimodal Therapy显示文摘 | Shigenori Nagata Yu-Fen Jin Katsuhiko Yoshizato Miki Tomoeda Misa Song Norishige Iizuka Masanori Kitamura Hidenori Takahashi Hidetoshi Eguchi Hiroaki Ohigashi Osamu Ishikawa Yasuhiko Tomita | 2009 | Annals of Surgical Oncology2009，，： | 2 |
| 5 | Successful production of piglets derived from vitrified morulae and early blastocysts using a microdroplet method显示文摘 | Kouji Misumi Misae Suzuki Shuji Sato Norio Saito | 2003 | Theriogenology2003，60，： | 1 |
| 6 | Gastrointestinal Stromal Tumors: Are They of Cajal Cell Origin?显示文摘 | Xiaojuan Wang Ichiro Mori Weihua Tang Hirotoshi Utsunomiya Misa Nakamura Yasushi Nakamura Genying Zhou Kennichi Kakudo | 2002 | Experimental and Molecular Pathology2002，，2： | 1 |
| 7 | Expression of Δ6, Δ5 desaturase and GLELO elongase genes from Mortierella alpina for production of arachidonic acid in soybean [ Glycine max (L.) Merrill] seeds显示文摘 | Ren Chen Keisuke Matsui Miyuki Ogawa Mieko Oe Misa Ochiai Hiroshi Kawashima Eiji Sakuradani Sakayu Shimizu Masao Ishimoto Makoto Hayashi Yoshikatsu Murooka Yoshikazu Tanaka | 2005 | Plant Science2005，，2： | 1 |
| 8 | Use of farinograph measurements for predicting extensograph traits of bread dough enricbed with carob fibre and oat wbolemeal显示文摘 | MisA Grundas S Dziki D | 2012 | Journal of Food Engineering2012，，108： | 1 |
| 9 | Biological evaluation of Cuban plants显示文摘 | Jimenez Misas CA Rojas Hernandez NM Lopez Abraham AM | 1979 | Rev Cubana Med Trop1979，31，1： | 1 |
| 10 | Relationahips between blood rheology and age, body mass index, blood cell count, fibrinogen, and lipids in healthy subjects 显示文摘 | Koji Seku Hiroyuki Sumino Misa Nara | 2006 | Clinical Hemortheology and Microcirculation2006，34，6： | 1 |
| 11 | Relationship of experience and the place of work to the level of competency among public health nurses in Japan显示文摘 | Reiko O Misa S Kimiko N | 2008 | Jpn J Nurs Sci2008，，5： | 1 |
| 12 | Regulation of a Novel Human Phospholipase C,PLCe,through Membrane Targeting by Ras显示文摘 | Chunhua S Chang -Deng H Misa M | 2001 | The Journal Of Biological Chemistry2001，276，4： | 1 |
| 13 | Heterologous expression of gentian MYB1R transcription factors suppresses anthocyanin pigmentation in tobacco flowers显示文摘 | Takashi Nakatsuka Eri Yamada Misa Saito Kohei Fujita Masahiro Nishihara | 2013 | Plant Cell Reports2013，，12： | 1 |
| 14 | Mechanisms of hypoglycem ic activity of ganoderan B: A glycan of ganodeima lucidum fruit bodies显示文摘 | Hiroshi Hikino Misae Ishiyama Yutaka Suzuki | 1989 | Planta Medica1989，55，： | 1 |
| 15 | Renewed Roles for Librarians in Problem-- Based Learning in the Medical Curriculum 显示文摘 | Misa Mi | 2011 | Medical Reference Services Quarterly2011，30，3： | 1 |
| 16 | Successful piglet production by IVF of oocytes matured in vitro using NCSU-37 supplemented with fetal bovine serum显示文摘 | Misae Suzuki Koji Misumi Manabu Ozawa Junko Noguchi Hiroyuki Kaneko Katsuhiko Ohnuma Dai-ichiro Fuchimoto Akira Onishi Masaki Iwamoto Norio Saito Takashi Nagai Kazuhiro Kikuchi | 2005 | Theriogenology2005，，2： | 1 |
| 17 | Isolation and characteriza- tion of GtMYBP3 and GtMYBP4, orthologues of R2R3- MYB transcription factors that regulate early flavonoid bio- synthesis, in gentian flowers 显示文摘 | Takashi N Misa S Eri Y | 2012 | J Exp Bot2012，63，18： | 1 |
| 18 | Effect of chemical etching by sulfuric acid or H 2 O 2 –NH 3 mixed solution on the photocatalytic activity of rutile TiO 2 nanorods显示文摘 | Eunyoung Bae Naoya Murakami Misa Nakamura Teruhisa Ohno | 2010 | Applied Catalysis A, General2010，，： | 1 |
| 19 | Creating random mutagenesis libraries using megaprimer PCR of whole plasmid显示文摘 | Kentaro M Misa T | | 0，，5： | 1 |
| 20 | 显示文摘 | Shigeru Kohtani Misa Tomohiro Kunihiro Tokumura | 2005 | Applied Catalysis B: Environmental2005，，58： | 1 |
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