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1解淀粉芽孢杆菌NS2降解玉米赤霉烯酮的研究显示文摘为了丰富玉米赤霉烯酮(ZEN)解毒菌种库,通过采集湖南省邵阳市等7个省市粮食样品,筛选获得1株能够高效降解ZEN的解淀粉芽孢杆菌NS2。采用高效液相色谱法检测降解前后ZEN的含量发现,液态发酵72 h,该菌对5 mg·L-1 ZEN标准品的降解率高达96.0%,固态发酵72 h,菌株对玉米粉中2.5 mg·L-1 ZEN标准品的降解率高达88.2%。采用高效液相色谱与四级杆飞行时间质谱联用技术检测该菌处理后的ZEN降解产物,未检测出具有毒性作用的α-玉米赤霉烯醇(α-ZOL)、β-玉米赤霉烯醇(β-ZOL)等ZEN的类似物。此外,抗菌活性试验与木聚糖酶、纤维素酶和蛋白酶活性试验显示降解菌NS2还能通过产生具有抗菌作用的次生代谢产物,抑制病原微生物大肠杆菌和鼠伤寒沙门氏菌的生长。上述结果表明,解淀粉芽孢杆菌NS2可以高效降解ZEN,具有潜在应用前景,为ZEN解毒产品的开发与应用奠定了材料基础。张晨曦 Yawa Minnie Elodie Folly 赵月菊 刘阳 2020核农学报2020,,7:7
2A prospective study on radiofrequency ablation locally advanced pancreatic cancer显示文摘BACKGROUND:Radiofrequency ablation(RFA)has been suggested as a new treatment option for patients with locally advanced cancer.This study aimed to prospectively evaluate the efficacy and safety of intraoperative RFA in patients with unresectable,locally advanced,non-metastatic carcinoma of the pancreatic head.METHODS:RFA was the first step of the surgical procedure and was carried out on the mobilized pancreatic head followed by biliary by-pass and gastrojejunal-anastomosis.Intra-and post-operative morbidity and mortality,performance status, pain control,quality of life,and survival at 24 months were evaluated.RESULTS:Seven patients(3 men and 4 women;median age 66 years,range 47-80 years)were studied and 4 were eligible for treatment.The RFA procedure was carried out in 3 of the 4 patients;in one patient it was not carried out because of the upstaging of the neoplasm.In all 3 patients RFA achieved complete necrosis of the lesion.A biliary fistula developed 7 days after the procedure in one patient;all 3 patients developed ascites 8.6 days(range 7-9 days)on average after RFA.All patients died respectively,at 3,4,and 5 months after the treatment.CONCLUSIONS:In our experience,RFA is a feasible procedure, but it presents a very high rate of postoperative complications.Moreover,pain control,life quality and survival rate are poor.The few data suggest no impact on survival.Riccardo Casadei Claudio Ricci Raffaele Pezzilli Carla Serra Lucia Calculli Antonio Maria Morselli-Labate Donatella Santini Francesco Minni 2010Hepatobiliary & Pancreatic Diseases International2010,9,3:6
3Endoscopic management of recurrent epistaxis: The experience of two metropolitan hospitals in Italy显示文摘Antonio Minni Alberto Dragonetti Roberto Gera Marco Barbaro Giuseppe Magliulo Roberto Filipo 2010Acta Oto-Laryngologica2010,,9:3
4Simultaneous curative resection of double colorectal carcinoma with synchronous bilobar liver metastases显示文摘Synchronous colorectal carcinoma(SCRC) indicates more than one primary colorectal carcinoma(CRC) discovered at the time of initial presentation, accounts for 3.1%-3.9% of CRC, and may occur either in the same or in different colorectal segments. The accurate preoperative diagnosis of SCRC is difficult and diagnostic failures may lead to inappropriate treatment and poorer prognosis. SCRC requires colorectal resections tailored to individual patients, based on the number, location, and stage of the tumours, from conventional or extended hemicolectomies to total colectomy or proctocolectomy, when established predisposing conditions exist. The overall perioperative risks of surgery for SCRC seem to be higher than for solitary CRC. Simultaneous colorectal and liver resection represents an appealing surgical strategy in selected patients with CRC and synchronous liver metastases(CRLM), even though the cumulative risks of the two procedures need to be adequately evaluated. Simultaneous resections have the noticeable advantage of avoiding a second laparotomy, give the opportunity of an earlier initiation of adjuvant therapy, and may significantly reduce the hospital costs. Because an increasing number of recent studies have shown goodresults, with morbidity, perioperative hospitalization, and mortality rates comparable to staged resections, simultaneous procedures can be selectively proposed even in case of complex colorectal resections, including those for SCRC and rectal cancer. However, in patients with multiple bilobar CRLM, major hepatectomies performed simultaneously with colorectal resection have been associated with significant perioperative risks. Conservative or parenchymal-sparing hepatectomies reduce the extent of hepatectomy while preserving oncological radicality, and may represent the best option for selected patients with multiple CRLM involving both liver lobes. Parenchymal-sparing liver resection, instead of major or two-stage hepatectomy for bilobar disease, seemingly reduces the overall operative risk of candidates to simultaneous colorectal and liver resection, and may represent the most appropriate surgical strategy whenever possible, also for patients with advanced SCRC and multiple bilobar liver metastases.Emilio De Raffele Mariateresa Mirarchi Dajana Cuicchi Ferdinando Lecce Claudio Ricci Riccardo Casadei Bruno Cola Francesco Minni 2018World Journal of Gastrointestinal Oncology2018,10,10:3
5Simultaneous colorectal and parenchymal-sparing liver resection for advanced colorectal carcinoma with synchronous liver metastases:Between conventional and mini-invasive approaches显示文摘The optimal timing of surgery in case of synchronous presentation of colorectal cancer and liver metastases is still under debate.Staged approach,with initial colorectal resection followed by liver resection(LR),or even the reverse,liver-first approach in specific situations,is traditionally preferred.Simultaneous resections,however,represent an appealing strategy,because may have perioperative risks comparable to staged resections in appropriately selected patients,while avoiding a second surgical procedure.In patients with larger or multiple synchronous presentation of colorectal cancer and liver metastases,simultaneous major hepatectomies may determine worse perioperative outcomes,so that parenchymal-sparing LR should represent the most appropriate option whenever feasible.Mini-invasive colorectal surgery has experienced rapid spread in the last decades,while laparoscopic LR has progressed much slower,and is usually reserved for limited tumours in favourable locations.Moreover,mini-invasive parenchymal-sparing LR is more complex,especially for larger or multiple tumours in difficult locations.It remains to be established if simultaneous resections are presently feasible with mini-invasive approaches or if we need further technological advances and surgical expertise,at least for more complex procedures.This review aims to critically analyze the current status and future perspectives of simultaneous resections,and the present role of the available miniinvasive techniques.Emilio De Raffele Mariateresa Mirarchi Dajana Cuicchi Ferdinando Lecce Riccardo Casadei Claudio Ricci Saverio Selva Francesco Minni 2020World Journal of Gastroenterology2020,26,42:3
6Phytoremediation of soil metals显示文摘Rufus L Chaney Minnie Malik Yin M Li Sally L Brown Eric P Brewer J Scott Angle Alan JM Baker 1997Current Opinion in Biotechnology1997,,3:2
7Phytoremediation of soil metals显示文摘Chancy R L Minnie M Li Y M 1997Current Opinion in Biotechnology1997,,8:1
8Photoemission study of the elec- tronic structure of Mo and Mo oxides显示文摘WERFEL F MINNIE Journal of Physies: C0,6,31:1
9Radiative effect differences between multi- layered and single - layer clouds derived from CERES, CALIPSO, and CloudSat data显示文摘Li J Yi Y Minnis P 2011Journal of Quantitative Spectros- copy and Radiative Transfer2011,2,:1
10Phytoremediation of soil metals 显示文摘Chancy R L Minnie M Li Y M 1997Current Opinion in Biotechnology1997,8,:1
11Dust aerosol effect on semi - arid climate over Northwest China detected from A - Train satellite measurements显示文摘Huang J P Minnis P Wang S W 2010Atmospheric Chemistry and Physics2010,10,:1
12Effect of palladium on sulfide tarnishing of noble metal alloys 显示文摘SUONINEN E HERO H MINNI E 1985Journal of Biomedical Materials Research1985,19,8:1
13Supracricoid partial laryngectomies:oncologic and functional results显示文摘DE VINCENTIIS M MINNI A GALLO A 1998Head Neck1998,20,:1
14Satellite - based assessment of possible dust aerosols semi -direct effect on cloud water path over East Asia显示文摘Huang J Lin B Minnis P 2006Geophys Res Lett2006,,19:1
15Concurrent hypermethylation of multiple tumor‐related genes in gastric carcinoma and adjacent normal tissues显示文摘Wai K.Leung JunYu Enders K. W.Ng Ka FaiTo Po K.Ma Tin LapLee Minnie Y.Y.Go S. C. SydneyChung Joseph J. Y.Sung 2001Cancer2001,,12:1
16Adherent Escherichia coli in colorectal mucosal biopsies: A histological and ultrastructural evaluation显示文摘Susama Patra Subash Samal Gagandeep Kang Anna Pulimood Minnie Mathan Balakrishnan Ramakrishna 2012Indian Journal of Pathology and Microbiology2012,,4:1
17Phytoremediation of soils metals 显示文摘Chaney R L Minnie M Li Y M 1997Current Opinion in Biotechnology1997,8,:1
18Phytore mediation of soil metals 显示文摘Chaney R L Minnie M Li Y M 1997Current Opinion in Bioteehnology1997,8,:1
19Long-range transport and vertical structure of Asian dust from CALIPSO and surface measurements during PACDEX 显示文摘Huang J P Minnis P Chen B 2008Journal Geophysical Research2008,113,23:1
20Phytoremediation of soil metals显示文摘Chaney R L Minnie M Li Y M 1997Current opinion in Biotechnology1997,8,:1
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