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| 1 | Architecture of PtFe/C catalyst with high activity and durability for oxygen reduction reaction显示文摘PtFe/C 催化剂被列在后面由的受精和高温度的减小综合了酸沥滤。X 光检查衍射, X 光检查光电子光谱学和在边光谱学描述附近原子的 X 光检查揭示那磅 < 潜水艇 class= “ a-plus-plus ” > 3 Fe 合金形成发生在高温度的减小和那不稳定的 Fe 种期间被溶解进酸溶液。在到表面并且强壮的 O-Fe 结合的从核心区域的 Fe 集中的差别可以驾驶 Fe 的外面的散开到高度弄皱的磅骨骼,并且高度结果驱散表面 FeO <潜水艇class=“ a-plus-plus ”> x 在酸的媒介是稳定的,导致磅的构造<潜水艇class=“ a-plus-plus ”> 3 Fe@Pt-FeO <潜水艇class=“ a-plus-plus ”> x 建筑学。是准备了 PtFe/C 催化剂与 Pt/C 催化剂相比为氧减小反应表明一项更高的活动和可比较的耐久性,它可能在 PtFe/C 催化剂由于表面和表面下的 Fe 种类的合作效果。 | Jiayuan Li Guoxiong Wang Jing Wang Shu Miao Mingming Wei Fan Yang Liang Yu Xinhe Bao | 2014 | Nano Research2014，7，10： | 8 |
| 2 | Hedgehog signaling in gastrointestinal carcinogenesis and the gastrointestinal tumor microenvironment显示文摘The Hedgehog(HH) signaling pathway plays important roles in gastrointestinal carcinogenesis and the gastrointestinal tumor microenvironment(TME). Aberrant HH signaling activation may accelerate the growth of gastrointestinal tumors and lead to tumor immune tolerance and drug resistance.The interaction between HH signaling and the TME is intimately involved in these processes, for example, tumor growth, tumor immune tolerance, inflammation, and drug resistance. Evidence indicates that inflammatory factors in the TME, such as interleukin 6(IL-6) and interferon-g(IFN-g), macrophages, and T cell-dependent immune responses, play a vital role in tumor growth by affecting the HH signaling pathway. Moreover, inhibition of proliferating cancer-associated fibroblasts(CAFs) and inflammatory factors can normalize the TME by suppressing HH signaling. Furthermore, aberrant HH signaling activation is favorable to both the proliferation of cancer stem cells(CSCs) and the drug resistance of gastrointestinal tumors. This review discusses the current understanding of the role and mechanism of aberrant HH signaling activation in gastrointestinal carcinogenesis, the gastrointestinal TME,tumor immune tolerance and drug resistance and highlights the underlying therapeutic opportunities. | Jinghui Zhang Jiajun Fan Xian Zeng Mingming Nie Jingyun Luan Yichen Wang Dianwen Ju Kai Yin | 2021 | Acta Pharmaceutica Sinica B2021，11，3： | 5 |
| 3 | A Volumetric Model for Evaluating Tight Sandstone Gas Reserves in the Permian Sulige Gas Field,Ordos Basin,Central China显示文摘To accurately measure and evaluate reserves is critical for ensuring successful production of unconventional oil and gas. This work proposes a volumetric model to evaluate the tight sandstone gas reserves of the Permian Sulige gas field in the Ordos Basin. The reserves can be determined by four major parameters of reservoir cutoffs, net pay, gas-bearing area and compression factor Z, which are controlled by reservoir characteristics and sedimentation. Well logging, seismic analysis, core analysis and gas testing, as well as thin section identification and SEM analysis were used to analyze the pore evolution and pore-throat structure. The porosity and permeability cutoffs are determined by distribution function curve,empirical statistics and intersection plot. Net pay and gas-bearing area are determined based on the cutoffs, gas testing and sand body distribution, and the compression factor Z is obtained by gas component. The results demonstrate that the reservoir in the Sulige gas field is characterized by ultralow porosity and permeability, and the cutoffs of porosity and permeability are 5% and 0.15×10^(–3) μm^2, respectively. The net pay and gas-bearing area are mainly affected by the sedimentary facies, sand body types and distribution. The gas component is dominated by methane which accounts for more than 90%, and the compression factor Z of H_8(P_2h_8) and S_1(P_1s_1) are 0.98 and 0.985, respectively. The distributary channels stacked and overlapped, forming a wide and thick sand body with good developed intergranular pores and intercrystalline pores. The upper part of channel sand with good porosity and permeability can be sweet spot for gas exploration. The complete set of calculation systems proposed for tight gas reserve calculation has proved to be effective based on application and feedback. This model provides a new concept and consideration for reserve prediction and calculation in other areas. | CUI Mingming FAN Aiping WANG Zongxiu GAO Wanli LI Jinbu LI Yijun | 2019 | Acta Geologica Sinica(English Edition)2019，93，2： | 4 |
| 4 | Expert consensus on perioperative management of liver transplantation in adults with acute-on-chronic liver failure显示文摘Acute-on-chronic liver failure(ACLF)is a syndrome in which acute liver failure with extrahepatic organ failure occurs on chronic liver disease.Recently,liver transplantation is the only effective treatment for ACLF.There is still room for discussion on the optimal surgery timing for ACLF,perioperative infection prevention and control,and maintenance of nutrition and organ function.The Transplantation Immu-nology Committee of Branch of Organ Transplantation Physician of Chinese Medical Doctor Association and Enhanced Recovery of Liver Transplantation Group of Enhanced Recovery after Surgery Committee of Chinese Research Hospital Association invited relevant experts to discuss the perioperative management of ACLF liver transplantation in areas including surgery timing,organ protection,nutritional support,infection prevention and control,rehabilitation exercises,regulation of the internal environment,etc.An expert consensus was developed as reference for clinicians. | Transplantation Immunology Committee of Branch of Organ Transplantation Physician of Chinese Medical Doctor Association Enhanced Recovery of Liver Transplantation Group of Enhanced Recovery after Surgery Committee of Chinese Research Hospital Society Guihua Chen Yang Yang Huimin Yi Jianrong Liu Pinglan Lu Lijuan Li Mingming Fan Xiaomeng Yi Haijin Lv Xuxia Wei | 2021 | Liver Research2021，5，2： | 3 |
| 5 | Preparation of mesoporous MgO-templated carbons from phenolic resin and their applications for electric double-layer capacitors显示文摘Mesoporous carbons were synthesized using thermoplastic phenolic resin(PF) as carbonaceous precursor and magnesium citrate as template precursor.Pore structure was determined as ink-bottle-like geometry through TEM,N2 adsorption analysis combined with TG curves.The porous carbons prepared were then applied as electrode material for electric double-layer capacitors.The capacitor performance was examined in 30 wt% KOH aqueous solution by cyclic voltammetry and galvanostatic charge/discharge measurements.The carbon prepared with MgO/PF mass ratio of 8/2 had a BET surface area of 1920 m2 g-1 and exhibited a capacitance of 220 F g-1 at a current density of 50 mA g-1.Besides,the carbon with the ratio of 4/6 had the optimize proportion of mesopores,which ensures its good rate performance that up to 98.3%,expressed as the ratio of the capacitance measured at 1000 mA g-1 against that at 50 mA g-1. | LIU WenJie WANG ChengYang WANG JiuZhou JIA Fan ZHENG JiaMing CHEN MingMing | 2013 | Chinese Science Bulletin2013，58，9： | 2 |
| 6 | Provenance of the Permo-Carboniferous sediments in the northern Alxa and its tectonic implications for the southernmost Central Asian Orogenic Belt显示文摘As the southernmost segment of the Central Asian Orogenic Belt(CAOB),the northern Alxa orogenic belt(NAOB)connects the southeastern and southwestern segments of the CAOB.The NAOB amalgamated with the closure of the Paleo-Asian Ocean;however,the closure time of the Paleo-Asian Ocean is still on great debate.In this study,we reported new detrital zircon U-Pb geochronology and Hf-O isotopes for the Permo-Carboniferous sediments in the northern Alxa to constrain the provenance and its tectonic implications.The Permo-Carbonifereous Amushan Formation is composed of volcanic-carbonite-clastic rocks and was deposited in a shallow marine environment.Based on the zircon U-Pb geochronology,the Amushan Formation was deposited in the late Carboniferous to early Permian,but some outcrops of volcanic and clastic rocks in the Quaganqulu area were likely formed in the middle to late Permian.The integrated zircon age spectrum for the clastic rocks shows a wide range from late Archean to Paleoproterozoic,Mesoproterozoic(with a peak age at 1458 Ma),early Neoproterozoic(with peak ages of 988 Ma and 929 Ma),early Paleozoic(with a peak age at 447 Ma) and late Paleozoic(with a peak age at 294 Ma).Combined with the zircon Hf-O isotopes,the provenance was considered to be the Alxa Block,the Shalazhashan terrane and the Zhusileng-Hangwula block(and the southern Beishan orogenic belt).The multiple source regions to the south and north of the Paleo-Asian Ocean indicate the closure of this ocean before the late Carboniferous.The absence or small proportion of depositional age-approximated zircons in most samples makes their age spectra similar to extensional basins.Combined with the intra-plate volcanism,the deposits were considered to be formed in extensional settings.Accordingly,after the closure of the Paleo-Asian Ocean,the NAOB stepped into an extensional stage. | Yan Chen Tairan Wu Zhicheng Zhang C.Mark Fanning Mingming Zhang Mingming Zhang | 2020 | Geoscience Frontiers2020，11，4： | 2 |
| 7 | Application and optimization of solid-state fermentation process for enhancing polygalacturonase production by Penicillium expansum显示文摘Penicillium expansum 3.5425 was applied in solid-state fermentation(SSF)of agricultural wastes for polygalacturonase biosynthesis.Among various carbon additives,apple pomace was most suitable for the biosynthesis of polygalacturonase(1440.57 U/g).Optimization of medium parameters using rotational orthogonal design(ROD)experiment combined with optimal fermentation conditions resulted in a 2.72-fold increase in the polygalacturonase production.By using ammonium sulphate precipitation,ion-exchange and gel-permeation chromatography,the polygalacturonase produced by P.expansum 3.5425 was finally purified which had specific activity of 19269 U/mg and molecular weight of 30 kDa.The enzyme was remarkably active in the pH range of 3-5 and at 50℃,which makes it more acceptable in the industrial application.Besides,partially purified polygalacturonase(875.15 U/mL)was used for apple juice clarification and the clarity at 0.4 mL/kg was maximum,which reveals a great potential of polygalacturonase in food industry. | Mingming Zhu Hongju He Mingtao Fan Hanjun Ma Haiwei Ren Jie Zeng Haiyan Gao | 2018 | International Journal of Agricultural and Biological Engineering2018，11，6： | 2 |
| 8 | Research on the Heat Transfer Characteristics of a Loop Heat Pipe Used as Mainline Heat Transfer Mode for Spacecraft显示文摘An experimental research is conducted on the heat transfer characteristics of a loop heat pipe(LHP)used in the'mainline'heat transfer mode for spacecraft platform thermal control.The heat from multiple instruments scattered in different locations is collected by thermal control techniques such as axially grooved heat pipes and then transmitted to the radiant surface for dissipation through the LHP in an unified way.The research contents include the start-up characteristics,the operational stability characteristics,the operational blocking characteristics,the continuous blocking characteristics,the heat transfer capability,the thermal resistance,and the dynamic response characteristics under the change of the heat sink temperature.The results show that the higher the auxiliary starting power is,the easier it is to start the LHP;the higher the input power of the thermoelectric cooler is,the more beneficial it is to speed up the stabilization of the vapor-liquid interface in the condenser;the higher the blocking power,the shorter the blocking time of the LHP;the LHP can be operated stably within the heat sink temperature alteration process;the heat transfer ability is higher than 500 W with a systematic thermal resistance of 0.037℃/W. | WANG Lu MIAO Jianyin GONG Mingming ZHOU Qiangu LIU Changu ZHANG Hongxing FAN Hanlin | 2019 | Journal of Thermal Science2019，28，4： | 2 |
| 9 | The chemical chaperon 4-phenylbutyric acid ameliorates hepatic steatosisthrough inhibition of de novo lipogenesis in high-fructose-fed rats显示文摘 | Lu-Ping Ren Guang-Yao Song Zhi-Juan Hu Mingming Zhang Lanbo Peng Shu-Chun Chen Limin Wei Fan Li Wen Sun | 2013 | International Journal of Molecular Medicine2013，，： | 2 |
| 10 | Magnetic solid base catalyst CaO/CoFe204 for biodiesel production:Influence of basici- ty and wettability of the catalyst in catalytic performance显示文摘 | Zhang Pingbo Han Qiuju Fan Mingming | 2014 | Appl Surf Sci o2014，317，： | 1 |
| 11 | Recent development of ceria-based (nano) composite materials for low temperature ceramic fuel cells and electrolyte-free fuel cells显示文摘 | Liangdong Fan Chengyang Wang Mingming Chen | 2013 | Journal of Power Sources2013，1，234： | 1 |
| 12 | FRET-based polymer materials for detection of cellular microenvironments显示文摘Effective detection of cellular microenvironments and understanding of physiological activities in living cells remain a considerable challenge.In recent years,fluore scence(or Forster)resonance energy trans fe r(FRET)technology has emerged as a valuable method for real-time imaging of intracellular environment with high sensitivity,specificity and spatial resolution.Particularly,polymer-based imaging systems show enhanced stability,improved biodistribution,increased dye payloads,and amplified signal/noise ratio compared with small molecular sensors.This review summarizes the recent progress in FRET-based polymeric systems for probing the physiological environments in cells. | Chuang Weng Nianqing Fan Taoran Xu Haodong Chen Zifen Li Yiwen Li Hong Tan Qiang Fu Mingming Ding | 2020 | Chinese Chemical Letters2020，31，6： | 1 |
| 13 | Study on the catalytic synthesis of diethyl carbonate from CO and ethyl nitrite over supported Pd catalysts 显示文摘 | Ma Xinbin Fan Mingming Zhang Pingbo | 2004 | Catalysis Communications2004，5，12： | 1 |
| 14 | Identification of quantitative trait loci associated with resistance to Xanthomonas oryzae pv. oryzae pathotypes prevalent in South China显示文摘Bacterial blight(BB), which is caused by Xanthomonas oryzae pv. oryzae(Xoo), is an important rice disease responsible for significant yield losses. In the rice-growing regions of South China where BB outbreaks are common, the resistance of cultivars with BB resistance genes Xa4 and Xa21 has been lost because of rapid changes in the Xoo population structure and virulence. In this study, 421 diverse rice accessions were evaluated regarding their resistance to two Xoo strains, namely GD1358(C5) and IV, which are prevalent pathotypes in South China and overcame the resistance of Xa4 and Xa21, respectively. Using the 4.8 mio filtered SNP dataset, we conducted a genome-wide association study, which identified 13 loci associated with BB resistance, including eight new quantitative trait loci(QTL) and five QTL harboring known BB resistance genes: Xa3/Xa26, xa5, Xa35(t), Xa36(t), Xa40, Xa43(t), and xa44(t). Intriguingly, a steep peak was detected on chromosomes 5 and 11. Six QTL including three new ones, were distributed on chromosome 11, whereas a new QTL q BB5.1 and a known QTL were detected on chromosome 5. Haplotype analyses indicated that the LOC;s05 g01610(Os PRAF2) gene within the q BB5.1 region, which encodes a PRAF protein, is associated with BB resistance. Furthermore, Os PRAF2 knockout lines generated using the CRISPR-Cpf1 system were significantly more resistant to Xoo strains than the wild-type plants. Our results provide researchers and breeders with useful information regarding QTL and gene resources,which may be relevant for developing new BB-resistant rice cultivars. | Jialing Lu Quanlin Li Chunchao Wang Mingming Wang Dan Zeng Fan Zhang Wenxue Zhai Yongli Zhou | 2022 | The Crop Journal2022，10，2： | 1 |
| 15 | Tranexamic acid reduces postoperative blood loss of degenerative lumbar instability with stenosis in posterior approach lumbar surgery: a randomized controlled trial显示文摘 | Qi Wang Jun Liu Rong Fan Yu Chen Hailong Yu Yan Bi Zhengzhe Hua Meihui Piao Mingming Guo Weijian Ren Liangbi Xiang | 2013 | European Spine Journal2013，，9： | 1 |
| 16 | Enhancement of biodiesel synthesis from soybean oil by potassium fluoride modification of a calcium magnesium oxides catalyst显示文摘 | Fan Mingming Zhang Pingbo Ma Qinke | 2012 | Bioresource Technology2012，104，： | 1 |
| 17 | A novel waste water scale-derived solid base catalyst for biodiesel production显示文摘 | Pingbo Zhang Qiuju Han Mingming Fan Pingping Jiang | 2014 | Fuel2014，，： | 1 |
| 18 | Monoclinic mesoporous BiVO 4 : Synthesis and visible-light-driven photocatalytic property显示文摘 | Mingming Yao Mingxian Liu Lihua Gan Fengqi Zhao Xuezhong Fan Dazhang Zhu Zijie Xu Zhixian Hao Longwu Chen | 2013 | Colloids and Surfaces A: Physicochemical and Engineering Aspects2013，，： | 1 |
| 19 | Oral nano-antioxidants improve sleep by restoring intestinal barrier integrity and preventing systemic inflammation显示文摘Sleep deprivation(SD)is a severe public health threat that can cause systemic inflammation and nerve damage.Few effective and side-effect-free drugs are available to address SD.However,the bidirectional communications between the brain and gut provide new strategies for anti-SD therapeutics.Here we explored oral delivery of fullerene nano-antioxidants(FNAO)in the SD model to improve sleep by regulating abnormal intestinal barrier and systemic inflammation via the brain-gut axis.SD caused excessive reactive oxygen species(ROS)production and hyperactive inflammatory responses in the intestines of zebrafish and mouse models,leading to disturbed sleep patterns and reduced brain nerve activity.Of note,based on the property of the conjugatedπbond of the C_(60)structure to absorb unpaired electrons,oral FNAO efficiently reduced the excessive ROS in the intestines,maintained redox homeostasis and intestinal barrier integrity,and ameliorated intestinal and systemic inflammation,resulting in superior sleep improvement.Our findings suggest that maintaining intestinal homeostasis may be a promising avenue for SD-related nerve injury therapy. | Zhanfeng Wu Lei Liu Lei Li Xinran Cao Wang Jia Xiaodan Liao Zhongpu Zhao Hedong Qi Guoqiang Fan Huiqiang Lu Chunying Shu Mingming Zhen Chunru Wang Chunli Bai | 2023 | National Science Review2023，10，12： | 1 |
| 20 | Photo-cata- lytic reduction of carbon dioxide with in-situ synthesis CoPc/TiO2 under visible light irradiation 显示文摘 | Zhao Zhihuan Fan Jimin Xie Mingming | 2009 | Journal of cleaner production2009，17，： | 1 |
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