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| 1 | 母猪的乳腺发育及其影响因素显示文摘母乳是哺乳仔猪重要的能量和营养物质来源,对乳仔猪的成活率和生长发育起决定性作用。母猪泌乳能力与其乳腺细胞的发育密切相关,两者可双向调控,并随着胎次呈现周期性变化。其中乳腺的发育主要受雌激素、松弛素和催乳素等体内激素的调节。而乳腺发育及激素分泌量受营养素和管理水平的影响较大。本文将从乳腺的发育、乳腺发育的激素调控、泌乳反馈、乳腺退化和营养与管理对母猪乳腺组织发育的影响等5个方面进行综述,为母猪的科学管理提供依据。 | 王丁 Merlin D.Lindemann 曾志凯 朴香淑 | 2017 | 中国畜牧杂志2017，53，2： | 9 |
| 2 | Creation of artificial karyotypes in mice reveals robustness of genome organization显示文摘Dear Editor,Robertsonian(Rb)fusions contribute to the diversity in species karyotypes.However,how it occurs and propels evolution is still unknown,mainly due to the lack of a simple and efficient method for genetically manipulating chromosomes in animals.While the typical mousekaryotype(2n=40)iscompletelytelocentric exceptchromosomeY(ChrY),thewestern European subspeciesM.m.domesticus contains diverse chromosomal races,with a diploid number varying between 38 and 22 due to carrying one or multiple pairs of metacentric chromosomes,which results from the Rb fusions between two telocentricchromosomes. | Xiaoyu Merlin Zhang Meng Yan Zhenhua Yang Hao Xiang Wei Tang Xindong Cai Qigui Wu Xin Liu Gang Pei Jinsong Li | 2022 | Cell Research2022，32，11： | 3 |
| 3 | In vivo anti-salmonella activity of aqueous extract of Euphorbia prostrata Aiton(Euphorbiaceae) and its toxicological evaluation显示文摘Objective: To investigate the in vivo anti-salmonella activity and the safety of aqueous extract of Euphorbia prostratra(E. prostratra), a plant commonly used in Cameroon by traditional healers.Methods: A Salmonella typhimurium-infected rat model was used for the study. The physiological, biochemical and histopathological markers of possible side effects of this extract were studied using standard methods.Results: The extract had a significant effect on the number of viable Salmonella typhimurium recovered from faeces, and could stop salmonellosis after 8 and 10 days of treatment for male and female rats, respectively, with non-toxic doses. However, the biochemical and histopathological analyses revealed that at relatively high doses(≥ 73.48 mg/kg for female and ≥ 122.71 mg/kg for male) the extract could induce liver damage, as illustrated by a rise of serum transaminases' levels and significant inflammation of the parenchyma and portal vein.Side effects were also observed on the kidneys, as shown by both serum and urinary creatinine,and urinary proteins.Conclusions: The overall results indicate that the aqueous extract of E. prostrata has the potential to provide an effective treatment for salmonellosis, including typhoid fever. However,it is necessary to extrapolate these results in large animals, in further studies. | Donald Sédric Tala Donatien Gatsing Siméon Pierre Chegaing Fodouop Charles Fokunang Fabrice Kengni Merline Namekong Djimeli | 2015 | Asian Pacific Journal of Tropical Biomedicine2015，5，4： | 3 |
| 4 | 室外涂饰木材的抗老化性能显示文摘通过测量气体渗透值研究室外涂饰木材在老化过程中的性能表现。结果表明:涂层渗透性与涂料的抗老化能力无直接关系;木材涂饰以后气体渗透值比未涂饰时均有所下降,在老化过程中涂饰木材的气体渗透值随着老化时间的增加而增加。木材径切面上的漆膜比弦切面上的抗老化,径切面上的渗透变化率kt和老化时间的关系为:渗透变化率在老化初期增长趋势很快,随着老化时间的增加逐渐变缓,到老化后期甚至出现渗透变化率下降的趋势。 | 陆步云 MERLIN A. PERRE P. CHRUSCIEL L. 周定国 | 2007 | 南京林业大学学报(自然科学版)2007，31，4： | 3 |
| 5 | Recent advances in orally administered cell-specific nanotherapeutics for inflammatory bowel disease显示文摘Inflammatory bowel disease(IBD) is a chronic relapsing disease in gastrointestinal tract. Conventional medications lack the efficacy to offer complete remission in IBD therapy,and usually associate with serious side effects. Recent studies indicated that nanoparticle-based nanotherapeutics may offer precise and safe alternative to conventional medications via enhanced targeting,sustained drug release,and decreased adverse effects. Here,we reviewed orally cell-specific nanotherapeutics developed in recent years. In addition,the various obstacles for oral drug delivery are also reviewed in this manuscript. Orally administrated cell-specific nanotherapeutics is expected to become a novel therapeutic approach for IBD treatment. | Xiao-Ying Si Didier Merlin Bo Xiao | 2016 | World Journal of Gastroenterology2016，22，34： | 3 |
| 6 | In vitro expansion of human sperm through nuclear transfer显示文摘Dear Editor,Mammalian haploid embryonic stem cells(haESCs)represent an ideal tool for genetic analysis due to the presence of only one set of genetic materials.HaESCs fall into two readily distinguishable groups based on their genome origins:parthenogenetic haESCs(PG-haESCs)that are derived from oocyte-originated parthenogenetic embryos and androgenetic haESCs(AG-haESCs)that are produced through sperm nuclear transfer.Both PG-and AGhaESCs are feasible for delineating genome function at cellular level in vitro.Importantly,AG-haESCs can be used as a sperm replacement and applied to deciphering gene function at organismal level when combined with CRISPR-Cas9 technology.1 However,while PG-haESCs have been generated from both rodent and primates,2-5 AG-haESCs can only be obtained in rodent to date. | Xiaoyu Merlin Zhang Keliang Wu Yuxuan Zheng Han Zhao Junpeng Gao Zhenzhen Hou Meiling Zhang Jiaoyang Liao Jingye Zhang Yuan Gao Yuanyuan Li Lin Li Fuchou Tang Zi-Jiang Chen Jinsong Li | 2020 | Cell Research2020，30，4： | 3 |
| 7 | Fab’-bearing siRNA TNFα-loaded nanoparticles targeted to colonic macrophages offer an effective therapy for experimental colitis显示文摘 | Hamed Laroui Emilie Viennois Bo Xiao Brandon S.B. Canup Duke Geem Timothy L. Denning Didier Merlin | 2014 | Journal of Controlled Release2014，，： | 2 |
| 8 | Drug-Loaded Nanoparticles Targeted to the Colon With Polysaccharide Hydrogel Reduce Colitis in a Mouse Model显示文摘 | Hamed Laroui Guillaume Dalmasso Hang Thi Thu Nguyen Yutao Yan Shanthi V. Sitaraman Didier Merlin | 2010 | Gastroenterology2010，，3： | 2 |
| 9 | Nanoparticles with Surface Antibody Against CD98 and Carrying CD98 Small Interfering RNA Reduce Colitis in Mice显示文摘 | Bo Xiao Hamed Laroui Emilie Viennois Saravanan Ayyadurai Moiz A. Charania Yuchen Zhang Zhan Zhang Mark T. Baker Benyue Zhang Andrew T. Gewirtz Didier Merlin | 2014 | Gastroenterology2014，，： | 2 |
| 10 | Mannosylated bioreducible nanoparticle-mediated macrophage-specific TNF-α RNA interference for IBD therapy显示文摘 | Bo Xiao Hamed Laroui Saravanan Ayyadurai Emilie Viennois Moiz A. Charania Yuchen Zhang Didier Merlin | 2013 | Biomaterials2013，，30： | 2 |
| 11 | 对钙和磷的进一步研究显示文摘 | 宋建国 Gary L Cromwell Merlin D Lindemann | 2002 | 国外畜牧学(猪与禽)2002，，6： | 2 |
| 12 | Spectroscopic and Structural Study of Complexes of Quercetin with Al (Ⅲ)显示文摘 | Cornard J P Merlin J C | | Journal of Inorganic0，，： | 1 |
| 13 | Wild-type p53 gene transfer into mutated p53 HT29 cells improves sensitivity to photodynamic therapy via induction of apoptosis显示文摘 | Vedrine PO Merlin JL | 2004 | Int J Oncol2004，24，： | 1 |
| 14 | Systematic review of endovenous laser treatment for varicose veins显示文摘 | Merlin TL Fitridge RA | 2005 | Br J Surg2005，92，： | 1 |
| 15 | In vitro comparative evaluation of trastuzumab (Herceptin) combined with paclitaxel (Taxol) or docetaxel (Taxotere) in HER2-expressing human breast cancer cell lines显示文摘 | Merlin JL Barbeir--Heyob M Bachmann N | 2002 | Ann Oncol2002，13，11： | 1 |
| 16 | High-frequen- cy operation of a DC/AC/DC system for HVDC application 显示文摘 | LUTH T MERLIN M M C GREEN T C | 2014 | IEEE Transactions on Power Electronics2014，29，8： | 1 |
| 17 | Sharing Customer Data in the Value Chain 显示文摘 | Merlin Stone Kevin Condron | 2002 | Journal of Database Management2002，9，2： | 1 |
| 18 | Spectroscopic and structural study of complexes of quercetin with AI(IⅢ)显示文摘 | Cornard J P Merlin J C | | 0，，01： | 1 |
| 19 | A new method for unit commitment Electricite de France 显示文摘 | MERLIN A SANDRIN P | 1983 | IEEE Trans on Power Apparatus and Systems1983，102，5： | 1 |
| 20 | The role of insertions/deletions in the evolution of the intergenic region between psbA and trnH in the chloroplast genome 显示文摘 | Aldrich J Chemey B W Merlin E | 1988 | Current Genetics1988，14，2： | 1 |
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