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| 1 | Cellular arsenic transport pathways in mammals显示文摘Natural contamination of drinking water with arsenic results in the exposure of millions of people world-wide to unacceptable levels of this metalloid. This is a serious global health problem because arsenic is a Group 1(proven) human carcinogen and chronic exposure is known to cause skin, lung, and bladder tumors. Furthermore, arsenic exposure can result in a myriad of other adverse health effects including diseases of the cardiovascular,respiratory, neurological, reproductive, and endocrine systems. In addition to chronic environmental exposure to arsenic, arsenic trioxide is approved for the clinical treatment of acute promyelocytic leukemia, and is in clinical trials for other hematological malignancies as well as solid tumors. Considerable inter-individual variability in susceptibility to arsenic-induced disease and toxicity exists, and the reasons for such differences are incompletely understood. Transport pathways that influence the cellular uptake and export of arsenic contribute to regulating its cellular, tissue, and ultimately body levels. In the current review, membrane proteins(including phosphate transporters, aquaglyceroporin channels, solute carrier proteins, and ATP-binding cassette transporters) shown experimentally to contribute to the passage of inorganic, methylated, and/or glutathionylated arsenic species across cellular membranes are discussed. Furthermore, what is known about arsenic transporters in organs involved in absorption, distribution, and metabolism and how transport pathways contribute to arsenic elimination are described. | Barbara A.Roggenbeck Mayukh Banerjee Elaine M.Leslie | 2016 | Journal of Environmental Sciences2016,28,11: | 7 |
| 2 | Correlating mode-I fracture toughness and mechanical properties of heat-treated crystalline rocks显示文摘For the effect of thermal treatment on the mode-I fracture toughness(FT), three crystalline rocks(two basalts and one tonalite) were experimentally investigated. Semi-circular bend specimens of the rocks were prepared following the method suggested by the International Society for Rock Mechanics(ISRM)and were treated at various temperatures ranging from room temperature(25 ℃) to 600 ℃. Mode-I FT was correlated with tensile strength(TS), ultrasonic velocities, and Young's modulus(YM). Additionally,petrographic and X-ray diffraction analyses were carried out to find the chemical changes resulting from the heat treatment. Further, scanning electron microscopy(SEM) was conducted to observe the micro structural changes when subjected to high temperatures. These experiments demonstrate that heat treatment has a strong negative impact on the FT and mechanical properties of the rocks. From room temperature to 600 ℃, mode-I FT values of massive basalt, giant plagioclase basalt, and tonalite were reduced by nearly 52%, 68%, and 64%, respectively. Also, at all temperature levels, FT and mechanical properties are found to be exponentially correlated. However, the exact nature of the relationship mainly depends on rock type. Besides, TS was found to be a better indicator of degradation degree than the mode-I FT. SEM images show that micro crack density and structural disintegration of the mineral grains increase with temperature. These physical changes confirm the observed reduction in the stiffness of heat-treated crystalline rocks. | Mayukh Talukdar Debanjan Guha Roy T.N.Singh | 2018 | Journal of Rock Mechanics and Geotechnical Engineering2018,10,1: | 3 |
| 3 | Increased chromosome aberration frequencies in the Bowen’s patients compared to non-cancerous skin lesions individuals exposed to arsenic显示文摘 | Pritha Ghosh Mayukh Banerjee Sujata De Chaudhuri Jayanta K. Das Nilendu Sarma Arindam Basu Ashok K. Giri | 2007 | MutRes-Genetic Toxicology and Environmental Mutagenesis2007,,1: | 1 |
| 4 | Population and genomic lessons from genetic analysis of two Indian populations显示文摘 | Garima Juyal Mayukh Mondal Pierre Luisi Hafid Laayouni Ajit Sood Vandana Midha Peter Heutink Jaume Bertranpetit B. K. Thelma Ferran Casals | 2014 | Human Genetics2014,,10: | 1 |
| 5 | Digital circuit applications of resonant tunneling devices显示文摘 | Pinaki M Shriram K Mayukh B | | 0,,04: | 1 |
| 6 | Modeling online art auction dynamics usting functional data analysis显示文摘 | SRINIVAS K R MAYUKH C A | 2006 | Statistical Science2006,21,2: | 1 |
| 7 | Recent advances in the design of biosensors based on novel nanomaterials:An insight显示文摘Biosensors have acquired much importance in drug discovery,medical diagnostics,food safety,defense,security,and monitoring of environmental conditions.Furthermore,there has been great progress in the potential applications of advanced nanomaterials in biosensors.Every year there are several advances in sensing techniques that can be attributed to nanomaterials,biorecognition elements,or their related fabrication techniques.The further development of nanotechnology-based sensors provides a wide variety of opportunities to modern research.Advanced nanomaterials can provide remarkable optical,electrical,mechanical,and catalytic properties.For example,transition metals and organic polymers have been used in the fabrication of powerful,sensitive,and precise biosensors.The distinctive properties of advanced nanomaterials have been widely incorporated into biosensors.However,fabrication techniques also play important roles in the development of these devices.Therefore,we present a review of some of the advanced nanomaterials that have been widely used over the last few years and discuss their fabrication techniques.The focus of this review is to provide a directional perspective of recently fabricated advanced nanomaterial-based biosensors in the diagnosis of various diseases. | Nidhi Chauhan Kirti Saxena Mayukh Tikadar Utkarsh Jain | 2021 | Nanotechnology and Precision Engineering2021,4,4: | 1 |
| 8 | Mechanism of erythrocyte death in human population exposed to arsenic through drinking water显示文摘 | Debabrata B Mayukh B Gargi S | 2008 | Toxicol Appl Pharm2008,230,1: | 1 |
| 9 | 查看详情显示文摘 | Polaske N W Lin H C Tang A Mayukh M Oquendo L E Green J T Ratcliff E L Armstrong N R Saavedra S S McGrath D V | | 0,,: | 1 |
| 10 | Comparison of health effects between individuals with and without skin lesion in the population exposed to arsenic through drinking water in West Bengal, India 显示文摘 | Pritha G Mayukh B Sujata DC | 2007 | J Expo Sci Env Epid2007,17,: | 1 |
| 11 | Modeling on-line art auction dynamics using functional data analysis显示文摘 | Srinivas K R Mayukh D | 2006 | Statistical Science2006,21,17: | 1 |
| 12 | Mini-invasive surgical repair of the Achilles tendon—does it reduce post-operative morbidity?显示文摘 | Mayukh Bhattacharyya Bruno Gerber | 2009 | International Orthopaedics2009,,1: | 1 |
| 13 | Ocular manifestation and visual outcomes in herpes zoster ophthalmicus:a prospective study from a tertiary hospital of Eastern India显示文摘AIM:To estimate the magnitude of different ocular manifestation in clinically established herpes zoster ophthalmicus(HZO)patients and assessment of the visual outcome after two months of initial examination.METHODS:An observational prospective study was conducted on 42 clinically diagnosed Tzanck smear positive cases HZO to observe the occurrence and frequency of different ocular manifestation and their visual outcome in 10-month period with 2mo follow up.Full ophthalmological examination using slit lamp,non-contact tonometry,applanation tonometry,direct and indirect ophthalmoscope were performed.RESULTS:Out of 42 patients of HZO,33 had one or more type of ocular manifestation staring from lid skin involvement to conjunctivitis,keratitis,uveitis,increased intraocular pressure(IOP)and optic neuritis but no retinal manifestation.More number of HZO cases and ocular manifestation were found with advancement of ages.Young HZO patients were more associated with human immunodeficiency virus(HIV)infection and HIV infected people with HZO infection had more ocular manifestation.Male to female ratio was 2:1 among HZO cases but ocular manifestation occurred more among males.Female with advanced age were involved more.Lid involvement(73.81%),conjunctivitis(69.05%),and keratitis(59.52%)were most common ocular manifestation followed by anterior uveitis(30.95%)and episcleritis(11.90%).Ocular hypertension(42.86%)was associated with almost every ocular manifestation.Among the cases of more than 45 years of age,9.52%patients acquired 6/6 vision compared to 7.14%patients at and below 45 years of age after 8wk of follow up.CONCLUSION:The visual outcomes are poor in HZO with advanced age group.Visual outcome of the affected eyes is poor than unaffected eyes.The loss of vision is mainly due to keratitis,anterior uveitis,posterior uveitis,and optic neuritis. | Mayukh Goswami Santanu Bhattacharya Manas Bandyopadhyay | 2021 | International Journal of Ophthalmology(English edition)2021,14,12: | 0 |