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| 1 | 马尾松抗松毛虫植株的抗性机制研究显示文摘本文研究了广西玉林地区、林科所1959年种植的马尾松抗虫11号植株的抗性机制。通过用抗11号松树对马尾松毛虫成虫产卵选择性试验和幼虫饲养试验。发现抗11号松树对成虫具有拒产卵性,对幼虫具有拒取食性。用抗11号松树针叶饲养的幼虫,出现发育迟缓,死亡率高,蛹重减轻等现象。本研究证明了抗11号松树对马尾松毛虫具有抗选择性和抗生性。抗虫性的主要原因是针叶内含物起了变化,产生拒成虫产卵及幼虫取食并致令生成营养屏障。 | The Research Group of the Resistance of Massion Pine to Masson Pine Moth | 1990 | 林业科学1990，26，2： | 22 |
| 2 | 军队男性包皮环切的历史回顾与展望显示文摘成人包皮环切可以预防大多数生殖道感染,显著降低男性获得性HPV、HSV和HIV的感染风险。有关男性包皮环切对军队服役人员健康益处的报道很少。前线的士兵不能保持阴囊与包皮足够的局部卫生条件,容易受到感染,影响执行任务和作战,辅助治疗也会直接给军队增加开支。在服役期间和在派遣之前进行包皮环切可以节省大量时间和成本,对改善官兵生殖健康状况起到长效的益处。这些研究发现正在受到非洲各国军队卫生部门的重视,将成为未来军队卫生和服务的发展方向。在HIV流行可能恶化的亚洲,在军队倡导男性包皮环切术预防生殖道感染和性传播疾病,对提高战斗力和降低医疗成本,增进全社会公众健康状况与国民经济将具有十分显著的战略意义。 | 李石华 吕年青 Puneet Masson 黄宇烽 孙颖浩 | 2010 | 中华男科学杂志2010，16，6： | 17 |
| 3 | The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation显示文摘MRE11/RAD50/NBS1 建筑群是很快招募到 DNA 双海滨裂缝(DSB ) 的主要传感器。MRE11 被知道是由在它的 glycine-arginine-rich (长嘴硬鳞鱼) 以内的 PRMT1 的精氨酸 methylated 主题。在这研究,我们报导在 GAR 主题与离氨酸代替精氨酸并且产生 MRE11 缺乏 methylated 精氨酸的 RK 蛋白质。Mre11 RK/RK 老鼠对 γ 过分敏感;照耀(红外) 和从这些老鼠的房间显示了房间周期检查点缺点和染色体不稳定性。而且, Mre11 RK/RK MEF 展出了在 RPA 和 RAD51 的招募表明缺点和缺陷到损坏地点的 ATR/CHK1。M RK 形成的 RN 建筑群并且对 DNA 损坏并且通常的地点局部性响应红外激活 ATM 小径。M RK RN 建筑群在为响应红外在 vivo 观察的损害 DNA 结束切除术和 ATR 激活负责的 vitro 展出了 exonuclease 和 DNA 有约束力的缺点。我们的调查结果在 DSB 修理为 MRE11 长嘴硬鳞鱼主题的关键角色提供基因证据,并且在 MRE11 长嘴硬鳞鱼表明在 translational 以后修正之间的一个机械学的连接主题并且 DSB 处理,以及发信号的 ATR/CHK1 检查点。 | Zhenbao Yu Gillian Vogel Yan Coulombe Danielle Dubeau Elizabeth Spehalski Josee Hebert David O Ferguson Jean Yves Masson Stephane Richard | 2012 | Cell Research2012，22，2： | 5 |
| 4 | Engine-Out Takeoff Path Optimization for Large Civil Aircraft显示文摘 | Bertrand Masson Michael Bain John Page | 2013 | Journal of Mechanics Engineering and Automation2013，3，6： | 4 |
| 5 | Current view and perspectives in amyotrophic lateral sclerosis显示文摘Amyotrophic lateral sclerosis(ALS), identified as a distinct clinical entity by Charcot since the end of the nineteenth century, is a devastating and fatal neurodegenerative disorder that affects motor neurons in the brain, brainstem and spinal cord. Survival of patients with ALS is associated with several factors such as clinical phenotype, age at onset, gender, early presence of respiratory failure, weight loss and treatment with Riluzole(the only disease-modifying drug approved for this disease). Nowadays, there is still no curative treatment for ALS: palliative care and symptomatic treatment are therefore essential components in the management of these patients. Nevertheless, the scientific knowledge in the field of ALS motor neuron degeneration is growing, with the prospect of new treatments. Based on this physiopathological knowledge, several new therapeutic targets are being studied, involving various mechanisms such as excitotoxicity, neuroinflammation, mitochondrial dysfunction, oxidative stress, RNA metabolism and other attractive concepts. Moreover, it is also important to identify reliable biomarkers that will be essential components for future therapeutic development and study design in ALS. In this review, we present the main recent advances and promising therapeutics and biomarkers in the field of ALS. | Stéphane Mathis Philippe Couratier Adrien Julian Philippe Corcia Gwendal Le Masson | 2017 | Neural Regeneration Research2017，12，2： | 3 |
| 6 | Predictive clinical features of cardioembolic infarction in patients aged 85 years and older显示文摘Objective To assess predictive clinical factors of cardioembolic infarction in very old patients(85 years of age and older).Methods Prospective hospital-based stroke registry('The Sagrat Cor Hospital of Barcelona Stroke Registry')is an acute-care teaching hospital in Barcelona,Catalonia,Spain.From 956 first-ever cardioembolic stroke patients included in the stroke registry over a 24-year period,639 were younger than 85 years of age and 317 were 85 years or older(mean age:88.9 years).Demographics,clinical characteristics,risk factors and early outcome were compared.Predictors of cardioembolic infarction in the oldest age group were assessed by multivariate analyses.Results In a logistic regression model based on demographics,risk factors,clinical features and complications,female gender(odds ratio[OR]=1.74,95%confidence interval[CI]:1.27–2.39),heart failure(OR=2.27,95%CI:1.46–3.56),altered consciousness(OR=1.76,95%CI:1.28–2.42),and infectious complications(OR=2.01,95%CI:1.39–2.91)were predictors of cardioembolic stroke in the oldest age group.By contrast,heavy smoking,heart valve disease,hypertension,headache,early seizures,sensory deficit,and involvement of the posterior cerebral artery were independently associated with cardioembolic stroke in the younger group.Conclusions Identification of a differential clinical profile of cardioembolic stroke between patients aged 85 years or more and those younger than 85 years helps clinicians to the optimal management of ischemic infarction in the oldest segment of the population. | Ana Maria Carbajo-García Jonatan Cortés AdriàArboix Joan Massons Laura Díez Enric Vergés Jordi Arboix-Alió Luís García-Eroles | 2019 | Journal of Geriatric Cardiology2019，16，11： | 3 |
| 7 | Value of a comprehensive geriatric assessment for predicting one-year outcomes in patients undergoing transcatheter aortic valve implantation: results from the CGA-TAVI multicentre registry显示文摘Background In a three-month report from the CGA-TAVI registry, we found the Multidimensional Prognostic Index (MPI) and Short Physical Performance Battery (SPPB) to be of value for predicting short-term outcomes in elderly patients undergoing transcatheter aortic valve implantation (TAVI). In the present analysis, we examined the association of these tools with outcomes up to one year post-TAVI. Methods CGA-TAVI is an international, observational registry of geriatric patients undergoing TAVI. Patients were assessed using the MPI and SPPB. Efficacy of baseline values and any postoperative change for predicting outcome were established using logistic regression. Kaplan- Meier analysis was carried out for each comprehensive geriatric assessment tool, with survival stratified by risk category. Results One year after TAVI, 14.1% of patients deceased, while 17.4% met the combined endpoint of death and/or non-fatal stroke, and 37.7% the combined endpoint of death and/or hospitalisation and/or non-fatal stroke. A high-risk MPI score was associated with an increased risk of all-cause mortality (aOR = 36.13, 95% CI: 2.77–470.78, P = 0.006) and death and/or non-fatal stroke (aOR = 10.10, 95% CI: 1.48–68.75, P = 0.018). No significant associations were found between a high-risk SPPB score and mortality or two main combined endpoints. In contrast to a worsening SPPB, an aggravating MPI score at three months post-TAVI was associated with an increased risk of death and/or non-fatal stoke at one year (aOR = 95.16, 95% CI: 3.41–2657.01). Conclusions The MPI showed value for predicting the likelihood of death and a combination of death and/or non-fatal stroke by one year after TAVI in elderly patients. | Martijn S.van Mourik Nathalie van der Velde Giulio Mannarino Marie-Pierre Thibodeau Jean-Bernard Masson Gennaro Santoro Jan Baan Sofie Jansen Jana Kurucova Martin Thoenes Cornelia Deutsch ANDreas W.Schoenenberger ANDrea Ungar Peter Bramlage M Marije Vis | 2019 | Journal of Geriatric Cardiology2019，16，6： | 3 |
| 8 | Antioxidant treatment attenuates hyperglycemia-induced cardiomyocyte death in rats显示文摘 | Fabio Fiordaliso Roberto Bianchi Lidia Staszewsky Ivan Cuccovillo Mirko Doni Teresa Laragione Monica Salio Costanza Savino Silvia Melucci Francesco Santangelo Eugenio Scanziani Serge Masson Pietro Ghezzi Roberto Latini | 2004 | Journal of Molecular and Cellular Cardiology2004，，5： | 2 |
| 9 | Impact of urban heat island on regional atmospheric pollution显示文摘 | C. Sarrat A. Lemonsu V. Masson D. Guedalia | 2005 | Atmospheric Environment2005，，10： | 2 |
| 10 | Biliary tract reconstruction using jejunal tube:an experimental study in dogs显示文摘BACKGROUND:To physiologically reconstruct the biliary tract,Crema et al suggested the application of the Monti principle to the biliary tract,already used in humans for the urinary tract.With this technique,a jejunal segment is transversely retubularized.This study aimed to evaluate the efficacy of jejunal tube interposition between the common bile duct and duodenum in dogs.METHODS:Thirteen dogs underwent a laparoscopic common bile duct ligature,followed by a biliodigestive connection by jejunal tube interposition after one week.The levels of glutamic-pyruvic and glutamic-oxalacetic transaminases,total bilirubins,alkaline phosphatase and gamma-glutamyltransferase were assessed before surgery and thereafter weekly until euthanasia,which was performed 6 weeks after biliodigestive connection.RESULTS:Data on 9 dogs were analyzed statistically.The dogs presented with obstructive jaundice after common bile duct ligature,as confirmed by biochemical examination.They showed a statistically significant reduction in cholestasis after biliodigestive connection by jejunal tube interposition and were healthy until the end of the experiment.CONCLUSION:A statistically significant reduction was seen in total bilirubin and canalicular enzymes(alkaline phosphatase and gamma-glutamyltransferase)in the 9 dogs 6 weeks after biliodigestive connetion by jejunal tube interposition. | Eliane Anrain Trentini Eduardo Crema Juan Carlos Llanos Mauro Masson Lerco Luiz Alberto Magna Luiz Sergio Leonardi | 2009 | Hepatobiliary & Pancreatic Diseases International2009，8，2： | 2 |
| 11 | XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage显示文摘 | Masson M Niedergang C Schreiber V | 1998 | Mol Cell Biol1998，18，6： | 2 |
| 12 | Deregulation of microRNA-503 Contributes to Diabetes Mellitus–Induced Impairment of Endothelial Function and Reparative Angiogenesis After Limb Ischemia显示文摘 | Andrea Caporali Marco Meloni Christine V?llenkle Desiree Bonci Graciela B. Sala-Newby Roberta Addis Gaia Spinetti Sergio Losa Rachel Masson Andrew H. Baker Reuven Agami Carlos le Sage Gianluigi Condorelli Paolo Madeddu Fabio Martelli Costanza Emanueli | 2011 | Circulation2011，，3： | 2 |
| 13 | Targeted gene expression in dopamine and serotonin neurons of the mouse brain 显示文摘 | Zhuang X Masson J Gingrich JA | 2005 | J Neurosci Methods2005，143，1： | 1 |
| 14 | High efficiency transformation of intact yeast cells by electric field pulses显示文摘 | Masson J M Teissie J | 1990 | Biotechnology1990，8，3： | 1 |
| 15 | Development of a fully coupled control-volume finite element method for the incompressible Navier-Stokes equations显示文摘 | Ammara I Masson C | 2004 | Int J Nurner Methods Fluids2004，44，6： | 1 |
| 16 | Lactoferrin inhibits the lipopolysaccharide-induced expresssion and proteoglycanbinding ability of interleukin-8 in human endothelial cells显示文摘 | ELASS E MASSON M MAZURIER J | 2002 | Infect mmun2002，70，： | 1 |
| 17 | High efficiency initiation of regenerable embryogenic callus from anther filaments of 19-grapevine genotypes grown worldwide显示文摘 | PERRIN M GERTZ C MASSON JE | 2004 | Plant Science2004，167，： | 1 |
| 18 | Lupus erythematosus panniculitis (lupus profundus ): clinical, histopathological, and molecular analysis of nine cases 显示文摘 | Massone C Kodama K Salmhofer W | 2005 | J Cutan Pathol2005，32，6： | 1 |
| 19 | G-CSF treatment prevents cyclophosphosphamide acceleration of autoimmune diabetes in the NOD mouse显示文摘 | Hadaya K Kared H Masson A | 2005 | J Autoimmun2005，24，2： | 1 |
| 20 | Rapid identification of escherichia coli pathotypes by virulence gene detection with DNA microarrays显示文摘 | Bekal S Brousseau R Masson L | 2003 | J Clin Microbiol2003，41，5： | 1 |
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