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| 1 | Split liver transplantation: Current developments显示文摘In 1988, Rudolf Pichlmayr pioneered split liver transplantation(SLT), enabling the transplantation of one donor liver into two recipients-one pediatric and one adult patient. In the same year, Henri Bismuth and colleagues performed the first full right/full left split procedure with two adult recipients. Both splitting techniques were rapidly adopted within the transplant community. However, a SLT is technically demanding, may cause increased perioperative complications, and may potentially transform an excellent deceased donor organ into two marginal quality grafts. Thus, crucial evaluation of donor organs suitable for splitting and careful screening of potential SLT recipients is warranted. Furthermore, the logistic background of the splitting procedure as well as the organ allocation policy must be adapted to further increase the number and the safety of SLT. Under defined circumstances, in selected patients and at experienced transplant centers, SLT outcomes can be similar to those obtained in full organ LT. Thus, SLT is an important tool to reduce the donor organ shortage and waitlist mortality, especially for pediatric patients and small adults. The present review gives an overview of technical aspects, current developments, and clinical outcomes of SLT. | Christina Hackl Katharina M Schmidt Caner Süsal Bernd Dohler Martin Zidek Hans J Schlitt | 2018 | World Journal of Gastroenterology2018，24，47： | 20 |
| 2 | 粉末注射成形不锈钢——制取工艺、性能、应用——显示文摘讨论了粉末注射成形可以制备哪些不锈钢 ;现在用粉末注射成形已能制备哪些不锈钢 ;在制备这些不锈钢时哪些工艺应特别予以关注。由这些不锈钢制成的MIM零件所能达到的磁性能、力学性能和耐腐蚀性能。最后 。 | Hans Wohlfromm Martin Blmacher Dieter Weinand 曹勇家 | 2002 | 粉末冶金工业2002，12，4： | 14 |
| 3 | Grazing effects on herbage nutritive values depend on precipitation and growing season in Inner Mongolian grassland显示文摘Aims Grasslands are widely used for production of livestock,which depend on the nutritive value of herbage species.However,there are still large uncertainties as to how grazing,precipitation and growing season interactively affect herbage nutritive value.Methods Here,based on a grazing experiment with seven grazing intensities in an Inner Mongolian grassland since the year 2005,we analysed nutritive value of four dominant grass species from June to September in both a relatively wetter year(2008)and a drier year(2010).Herbage with high nutritive value is characterized by high concentration of crude protein,high concentration of cellulase digestible organic matter and low concentration of neutral detergent fibre.Important Findings We found that(i)grazing significantly increased the nutritive value of Leymus chinensis,Agropyron michnoi and Cleistogenes squarrosa but had minor effects on the nutritive value of Stipa grandis.(ii)For all species,nutritive values were greater in the wetter year than in the drier year and were greatest in the early growing season(June)and lowest at the end of the growing season(September).Inter-annual and inter-seasonal variations in nutritive value were much greater for L.chinensis and A.michnoi than for C.squarrosa and S.grandis,suggesting higher water use efficiency for the latter two species.(iii)Grazing significantly decreased the drought resistance of three species,but not of S.grandis.(iv)Grazing significantly increased inter-month variation in nutritive value for L.chinensis and A.michnoi but had relatively minor or no effects on that of C.squarrosa and S.grandis.Therefore,grazing effects on species nutritive values showed strong inter-annual and seasonal patterns,and species-specific responses might be related to species traits(i.e.water use efficiency,digestibility).Our results have important implications for ecosystem management of arid and semiarid grasslands under intense grazing and global climatic change. | Haiyan Ren Guodong Han Zhichun Lan Hongwei Wan Philipp Schönbach Martin Gierus Friedhelm Taube | 2016 | Journal of Plant Ecology2016，9，6： | 14 |
| 4 | The Qitai radio telescope显示文摘This study presents a general outline of the Qitai radio telescope(QTT)project.Qitai,the site of the telescope,is a county of Xinjiang Uygur Autonomous Region of China,located in the east Tianshan Mountains at an elevation of about 1800 m.The QTT is a fully steerable,Gregorian-type telescope with a standard parabolic main reflector of 110 m diameter.The QTT has adopted an umbrella support,homology-symmetric lightweight design.The main reflector is active so that the deformation caused by gravity can be corrected.The structural design aims to ultimately allow high-sensitivity observations from 150 MHz up to115 GHz.To satisfy the requirements for early scientific goals,the QTTwill be equipped with ultra-wideband receivers and large field-of-view multi-beam receivers.A multi-function signal-processing system based on RFSo C and GPU processor chips will be developed.These will enable the QTT to operate in pulsar,spectral line,continuum and Very Long Baseline Interferometer(VLBI)observing modes.Electromagnetic compatibility(EMC)and radio frequency interference(RFI)control techniques are adopted throughout the system design.The QTT will form a world-class observational platform for the detection of lowfrequency(nano Hertz)gravitational waves through pulsar timing array(PTA)techniques,pulsar surveys,the discovery of binary black-hole systems,and exploring dark matter and the origin of life in the universe.The QTT will also play an important role in improving the Chinese and international VLBI networks,allowing high-sensitivity and high-resolution observations of the nuclei of distant galaxies and gravitational lensing systems.Deep astrometric observations will also contribute to improving the accuracy of the celestial reference frame.Potentially,the QTT will be able to support future space activities such as planetary exploration in the solar system and to contribute to the search for extraterrestrial intelligence. | Na Wang Qian Xu Jun Ma Zhiyong Liu Qi Liu Hailong Zhang Xin Pei Maozheng Chen Richard N.Manchester Kejia Lee Xingwu Zheng Hans J.Kärcher Wulin Zhao Hongwei Li Dongwei Li Martin Süss Matthias Reichert Zhongyi Zhu Congsi Wang Mingshuai Li Rui Li Ning Li Guljaina Kazezkhan Wenming Yan Gang Wu Lang Cui Ming Zhang Haitao Li | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，8： | 14 |
| 5 | Current developments in pediatric liver transplantation显示文摘In 1953, the pioneer of human orthotopic liver transplantation(LT), Thomas E Starzl, was the first to attempt an orthotopic liver transplant into a 3 years old patient suffering from biliary atresia. Thus, the first LT in humans was attempted in a disease, which, up until today, remains the main indication for pediatric LT(p LT). During the last sixty years, refinements in diagnostics and surgical technique, the introduction of new immunosuppressive medications and improvements in perioperative pediatric care have established LT as routine procedure for childhood acute and chronic liver failure as well as inherited liver diseases. In contrast to adult recipients, p LT differs greatly in indications for LT, allocation practice, surgical technique, immunosuppression and postoperative life-long aftercare. Many aspects are focus of ongoing preclinical and clinical research. The present review gives an overview of current developments and the clinical outcome of p LT, with a focus on alternatives to full-size deceased-donor organ transplantation. | Christina Hackl Hans J Schlitt Martin Loss Birgit Knoppke Michael Melter | 2015 | World Journal of Hepatology2015，7，11： | 13 |
| 6 | 中国的地面臭氧及其对农作物产量的可能影响显示文摘据估计,今后20年里,中国臭氧产生物质的排放量可能会成倍增长,光氧化剂的浓度也可能会显著增加。地面臭氧的增加导致对中国农业生产前景的关注。我们的研究表明,未来由于臭氧浓度的增加,作物产量可能会显著降低,某些作物生产力可能已经受到影响。然而,使用替代性暴露-响应函数所得到的作物产量损失的估计值却有明显的不同。春小麦、大豆和玉米可能特别容易受到未来臭氧增加的影响,因为臭氧浓度和这些作物的生长季节可能同时出现。 | Kristin Aunan Terje Koren Berntsen Hans Martin Seip 闵庆文 | 2000 | AMBIO-人类环境杂志2000，29，6： | 10 |
| 7 | Testicular expression of survivin and human telomerase reverse transcriptase(hTERT)associated with spermatogenic function in infertile patients显示文摘瞄准:与改变精子发生的功能在人的睾丸描绘 survivin, apoptosis (国际星际航空联合会) 的一个禁止者,和人的 telomerase 颠倒 transcriptase (hTERT ) 的 coexpression。方法:survivin mRNA 和 hTERT mRNA 的抄本层次用即时反向抄写的聚合酶链反应(RT-PCR ) 与有缺点的精子发生(n=28 ) 在正常睾丸(n=11 ) 和睾丸被决定。组织学的病情的检查根据一个修改 Johnsen 分数被执行。结果:survivin 和 hTERT 的表情在正常精子发生在 96.8 和 709 的中部的层次是最高的并且随减数分裂后精子发生的拘捕(n=10 ) 在睾丸落下到 53.3 和 534。在严重精子发生的失败( n=18 ), survivin 表示缺乏大多数标本( n=16 ),而阴囊的 hTERT 表示的至少底层在 premeiotic 精子发生的拘捕( n=7 )与 73 的规范的表情大部分是可检测的并且 45 在有 Sertoli 房间唯一的症候群( SCOS )( n=3 )的病人。survivin 和 hTERT 表情与一个进行的 Johnsen 分数(为 trend=0.001 的 P ) 增加了。结论:尽管 survivin 和 hTERT 与精子发生的功能被相关,他们在不肥沃的病人的睾丸显示出不同表示模式。这些调查结果在在 meiotically 划分生殖细胞建议 survivin 的占优势的表情的啮齿类动物睾丸从研究证实结果。 | Steffen Weikert Frank Christoph Wolfgang Schulze Hans Krause Carsten Kempkensteffen Martin Schostak Kurt Miller Mark Schrader | 2006 | Asian Journal of Andrology2006，8，1： | 8 |
| 8 | Efficacy and safety of FIREHAWK abluminal groove filled biodegradable polymer sirolimus-eluting stents for the treatment of long coronary lesions: nine-month angiographic and one-year clinical results from TARGET I trial lona cohort显示文摘 | XU Bo GAO Run-lin ZHANG Rui-yan WANG Hai-chang LI Zhan-quan YANG Yue-jin MA Chang-sheng HAN Ya-ling Alexandra J. Lansky HUO Yong LI Wei Martin B. Leon | 2013 | Chinese Medical Journal2013，，6： | 8 |
| 9 | Liver transplantation for malignancy:current treatment strategies and future perspectives显示文摘In 1967,Starzl et al performed the first successful liver transplantation for a patient diagnosed with hepatoblastoma.In the following,liver transplantation was considered ideal for complete tumor resection and potential cure from primary hepatic malignancies.Several reports of liver transplantation for primary and metastatic liver cancer however showed disappointing results and the strategy was soon dismissed.In1996,Mazzaferro et al introduced the Milan criteria,offering liver transplantation to patients diagnosed with limited hepatocellular carcinoma.Since then,liver transplantation for malignant disease is an ongoing subject of preclinical and clinical research.In this context,several aspects must be considered:(1)Given the shortage of deceased-donor organs,long-term overall and disease free survival should be comparable with results obtained in patients transplanted for nonmalignant disease;(2)In this regard,living-donor liver transplantation may in selected patients help to solve the ethical dilemma of optimal individual patient treatment vs organ allocation justice;and(3)Ongoing research focusing on perioperative therapy and antiproliferative immunosuppressive regimens may further reduce tumor recurrence in patients transplanted for malignant disease and thus improve overall survival.The present review gives an overview of current indications and future perspectives of liver transplantation for malignant disease. | Christina Hackl Hans J Schlitt Gabriele I Kirchner Birgit Knoppke Martin Loss | 2014 | World Journal of Gastroenterology2014，20，18： | 7 |
| 10 | Effects of Potassium and Manganese Promoters on Nitrogen-Doped Carbon Nanotube-Supported Iron Catalysts for CO_2 Hydrogenation显示文摘氮掺杂碳纳米管(NCNTs)作为载体负载铁(Fe)纳米颗粒,可应用于CO_2多相催化加氢反应(633 K和25 bar)。当将钾(K)和锰(Mn)作为助催化剂时,Fe/NCNT展现出优异的CO_2加氢性能,在体积空速(GHSV)为3.1 L·g^(–1)·h^(–1)时转化率可达34.9%。当使用K作为助催化剂时,反应对烯烃和短链烷烃具有高的选择性。当K和Mn同时作为助催化剂时,其催化活性能够稳定地维持60 h。助催化剂Mn的结构效应通过X射线衍射、氢气程序升温还原以及近边X射线吸收精细结构进行表征。助催化剂Mn不仅能够稳定中间态FeO,且能降低程序升温还原的起始温度。通过探针反应NH3的催化分解来表征助催化剂效应。当K和Mn作为助催化剂时,Fe/NCNT具有最好的催化活性。在还原条件下,当K作为助催化剂时,Fe/NCNT具有最优异的热稳定性。 | Praewpilin Kangvansura Ly May Chew Chanapa Kongmark Phatchada Santawaja Holger Ruland Wei Xia Hans Schulz Attera Worayingyong Martin Muhler | 2017 | Engineering2017，3，3： | 6 |
| 11 | A Treatment Algorithm for the Management of Chronic Hepatitis B Virus Infection in the United States: 2008 Update显示文摘 | Emmet B. Keeffe Douglas T. Dieterich Steven-Huy B. Han Ira M. Jacobson Paul Martin Eugene R. Schiff Hillel Tobias | 2008 | Clinical Gastroenterology and Hepatology2008，，12： | 5 |
| 12 | Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn’s disease: an open randomised trial显示文摘 | Geert D’Haens Filip Baert Gert van Assche Philip Caenepeel Philippe Vergauwe Hans Tuynman Martine De Vos Sander van Deventer Larry Stitt Allan Donner Severine Vermeire Frank J Van De Mierop Jean-Charles R Coche Janneke van der Woude Thomas Ochsenkühn Ad A | 2008 | The Lancet2008，，9613： | 5 |
| 13 | Discrete particle modeling of granular temperature distribution in a bubbling fluidized bed显示文摘The discrete hard sphere particle model (DPM) is applied in this work to study numerically the distributions of particle and bubble granular temperatures in a bubbling fluidized bed. The dimensions of the bed and other parameters are set to correspond to those of Müller et al. (2008). Various drag models and operational parameters are investigated to find their influence on particle and bubble granular temperatures. Various inlet superficial gas velocities are used in this work to obtain their effect on flow characteristics. It is found that the superficial gas velocity has the most important effect on granular temperatures including bubble granular temperature, particle translational granular temperature and particle rotational granular temperature. The drag force model affects more seriously the large scale variables such as the bubble granular temperature. Restitution coefficient influences all granular temperatures to some degree. Simulation results are compared with experimental results by Müller et al. (2008) showing reasonable agreement. | Yurong He Tianyu Wang Niels Deen Martin van Sint Annaland Hans Kuipers Dongsheng Wen | 2012 | Particuology2012，10，4： | 4 |
| 14 | Risk of Melanoma and Nonmelanoma Skin Cancer Among Patients With Inflammatory Bowel Disease显示文摘 | Millie D. Long Christopher F. Martin Clare A. Pipkin Hans H. Herfarth Robert S. Sandler Michael D. Kappelman | 2012 | Gastroenterology2012，，2： | 4 |
| 15 | Role of soluble factors and three-dimensional culture in in vitro differentiation of intestinal macrophages显示文摘AIM: To examine the factor(s) involved in differentiation of intestinal macrophages (IMACs) using a recently established in vitro model. METHODS: To test whether soluble or membrane bound factors induce IMAC-differentiation, freshly elutriated monocytes (MO) were incubated with conditioned media or cell membranes of intestinal epithelial cells (IEC) or cultured with IEC in transwell systems. To determine the importance of an active migration of MO, three- dimensional aggregates from a 1:1-mixture of MO and IEC were examined by immunohistochemistry and flow cytometry. Apoptosis was examined by caspase-3 Western blots. Extracellular matrix production in differentiation models was compared by immunohistochemistry. RESULTS: IMAC differentiation was observed in a complex three-dimensional co-culture model (multicellular spheroid, MCS) with IEC after migration of MO into the spheroids. By co-culture of MO with conditioned media or membrane preparations of IEC no IMAC differentiation was induced. Co-culture of MO with IEC in transwell- cultures, with the two cell populations separated by a membrane also did not result in intestinal-like differentiation of MO. In contrast to IEC-spheroids with immigrating MO in mixed MCS of IEC and MO only a small subpopulation of MO was able to survive the seven day culture period. CONCLUSION: Intestinal-like differentiation of MO in vitro is only induced in the complex three-dimensional MCS model after immigration of MO indicating a roleof cell-matrix and/or cell-cell interactions during the differentiation of IMACs. | Tanja Spoettl Martin Hausmann Katrin Menzel Heidi Piberger Hans Herfarth Juergen Schoelmerich Frauke Bataille Gerhard Rogler | 2007 | World Journal of Gastroenterology2007，13，7： | 3 |
| 16 | Emerging pollutants in the environment:A challenge for water resource management显示文摘A significant number of emerging pollutants(EPs)resulting from point and diffuse pollution is present in the aquatic environment.These are chemicals that are not commonly monitored but have the potential to enter the environment and cause adverse ecological and human health effects.According to the NORMAN network,at least 700 substances categorized into 20 classes,have been identified in the European aquatic environment.In light of their potential impact action is urgently required.In this study,we present a concept that shows the current state of art and challenges for monitoring programs,fate and risk assessment tools and requirements for policies with respect to emerging pollutants as a base for sustainable water resource management.Currently,methods for sampling and analysis are not harmonized,being typically focused on certain EP classes.For a number of known highly hazardous EPs detection limits are too high to allow proper risk assessment.For other EPs such as microplastics method development is in its infancy.Advanced ultra-sensitive instrumental techniques should be used for quantitative determination of prioritized EPs in water,suspended matter,soil and biota.Data on EPs'and their metabolites'properties that determine their fate in the environment are often not available.National surveys on water quality often use different parameters for water quality assessment and often do not include EPs.A harmonized monitoring of surface and groundwater is not yet achieved and urgently required.Specific component integrated into models assessing the fate of EPs in a multi compartment environmental approach are missing and must be developed.The main goal of risk assessment is the overall protection of ecological communities in the aquatic environment and human health.New methods for assessing the cumulative risks from combined exposures to several stressors,including mixtures of EPs in a multi-scale approach are required.A combination of regulations and management measures with respect to use/emissions of EPs into the environment,as well as to their occurrence in the environment are fundamental to reach an efficient water resource management. | Violette Geissen Hans Mol Erwin Klumpp Günter Umlauf Marti Nadal Martine van der Ploeg Sjoerd E.A.T.M.van de Zee Coen J.Ritsema | 2015 | International Soil and Water Conservation Research2015，3，1： | 3 |
| 17 | Corona Discharge Ion Mobility Spectrometry of Ten Alcohols显示文摘为十白酒的离子活动性系列在与日冕分泌物电离来源一起装备的一台离子活动性 spectrometry 仪器被学习了。作为飘移气体把 protonated 水簇离子用作反应物离子和干净空气,白酒在他们的离子活动性系列展出不同产品离子特征山峰。为这些白酒的察觉限制根据由指数的冲淡方法的集中刻度在低集中 pmol/L 水平。基于测量离子活动性,在空气的离子分子的相互作用的几个化学物理参数被获得包括离子的碰撞十字节,散开系数,碰撞率常数,和在难范围的模型近似下面的离子的半径。 | Hai-yan Han Hong-meiWang Hai-he Jiang Michal Stano Martin Sabo Stefan Matejcik Yan-nan Chu | 2009 | Chinese Journal of Chemical Physics2009，22，6： | 3 |
| 18 | Magnetic Resonance Imaging Surveillance Detects Early-Stage Pancreatic Cancer in Carriers of a p16-Leiden Mutation显示文摘 | Hans F.A. Vasen Martin Wasser Anneke van Mil Rob A. Tollenaar Marja Konstantinovski Nelleke A. Gruis Wilma Bergman Frederik J. Hes Daniel W. Hommes G. Johan A. Offerhaus Hans Morreau Bert A. Bonsing Wouter H. de Vos tot Nederveen Cappel | 2011 | Gastroenterology2011，，3： | 3 |
| 19 | A Treatment Algorithm for the Management of Chronic Hepatitis B Virus Infection in the United States: An Update显示文摘 | Emmet B. Keeffe Douglas T. Dieterich Steven–Huy B. Han Ira M. Jacobson Paul Martin Eugene R. Schiff Hillel Tobias Teresa L. Wright | 2006 | Clinical Gastroenterology and Hepatology2006，，8： | 2 |
| 20 | Signaling Pathways in Cardiac Myocyte Hypertrophy显示文摘 | Martin A. Hefti Beatrice A. Harder Hans M. Eppenberger Marcus C. Schaub | 1997 | Journal of Molecular and Cellular Cardiology1997，，11： | 2 |
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