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30篇 您的检索式:作者名="Martin Berry"
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1Decorin treatment of spinal cord injury显示文摘The scarring response after a penetrant central nervous system injury results from the interaction between invading leptominingeal/pericyte-derived fibroblasts and endogenous reactive astrocytes about the wound margin. Extracellular matrix and scar-derived axon growth inhibitory molecules fill the lesion site providing both a physical and chemical barrier to regenerating axons. Dec orin, a small leucine-rich chondroitin-dermatan sulphate proteoglycan expressed by neurons and astrocytes in the central nervous system, is both anti-fibrotic and anti-inflammatory and attenuates the formation and partial dissolution of established and chronic scars. Here, we discuss the potential of using Decorin to antagonise scarring in the central nervous system.Maryam Esmaeili Martin Berry Ann Logan Zubair Ahmed 2014Neural Regeneration Research2014,9,18:5
2Dental pulp stem cells, a paracrine-mediated therapy for the retina显示文摘The functional loss that occurs after retinal/optic nerve injury is permanent and can arise through trauma or neurodegenerative conditions such as glaucoma.Neurotrophic factors(NTFs)promote survival of injured retinal ganglion cells(RGCs)and regeneration of their axons。Ben Mead Ann Logan Martin Berry Wendy Leadbeater Ben A. Scheven 2014Neural Regeneration Research2014,9,6:2
3Sustained effects of gene-activated matrices after CN S injury显示文摘Martin Berry Ana Maria Gonzalez Wendy Clarke 2001Molecular and Cellular Neuroscience2001,17,4:1
4A genetical analysis of diversity and asymmetry in finger ridge counts显示文摘Martin NG Jinks JL Berry HS 0,,:1
5RNA and Protein Requirements for Eukaryotic Selenoprotein Synthesis显示文摘Selenium has been recognized as an essential nutrient in animals since the 1950s. Demonstration of the role of dietary selenium in protection from oxidative stress foIlowed in the early 1970s, and was largely attributed to its presence as an integral part of cellular glutathione peroxidase. However, the functions of this enzyme did not explain many of the other effects of selenium deficiency. The identification of other mammalian selenoproteins during the last few years has provided new insights into the functions of this trace nutrient. The discovery that type 1 deiodinase (D1) is a selenoenzyme, in addition to unveiling an essential role for selenium in thyroid hormone action, has had more far-reaching implications. Studies of this protein opened the door for investigation of the requirements for eukaryotic selenoprotein synthesis,and the features that distinguish this pathway from the corresponding prokaryotic pathway.Selenium is present in a number of prokaryotic and eukaryotic proteins in the form of the unusual amino acid, selenocysteine. Incorporation of selenocysteine into these proteins requires a novel translation step in which UGA specifies selenocysteine insertion. Since UGA codons are typically recognized as translation stop signals, an intriguing question is raised: How does a cell recognize and distinguish a UGA selenocysteine codon from a UGA stop codon? In this review, we will focus on what is known about selenocysteine incorporation in eukaryotes, briefly summarizing initial studies and discussing a few recent advances in our understanding of this unique 'recoding'MARLA J. BERRY GLOVER W. MARTIN Ⅲ, AND SUSAN C. LOW(Thyroid Division, Department of Medicine, Brigham and Women’s Hospital Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, Massachusetts 02115,USA) 1997Biomedical and Environmental Sciences1997,10,2:1
6Out- of-core SVD performance for document indexing显示文摘MARTIN D I MARTIN J C BERRY M W 1994Applied Numerical Mathematics1994,,:1
7Preparation and evaluation of the in vitro drug release properties and mucoadhesion of novel microspheres of hyaluronic acid and chitosan 显示文摘Lim ST Martin GP Berry DJ 2000J Control Release2000,66,:1
8Preparation and evaluation of the in vitro drug release properties and mucoadhesion d novel microsphere of hyaluronic acid and chitosan显示文摘Lim ST Martin GP Berry DJ 2000J Controlled Release2000,66,23:1
9Preparation and evaluation of the in vitro drug release properties and mucoadhesion of novel microspheres of hyaluronic acid and chitosan显示文摘S.T. Lim G.P. Martin D.J. Berry M.B. Brown 2000Journal of Controlled Release2000,,2:1
10Getting to the (c)ore of knowledge: mining biomedical literature 显示文摘Berry de Bruijn Joel Martin 2002International Journal of Medical Informatics2002,67,:1
11Salicylic acid can induce ressistance to plant virus movement 显示文摘Martin Naylor Alex M Murphy James O Berry 1998Siciences1998,11,9:1
12LINGO-1 and AMIGO3, potential therapeutic targets for neurological and dysmyelinating disorders?显示文摘Leucine rich repeat proteins have gained considerable interest as therapeutic targets due to their expression and biological activity within the central nervous system. LINGO-1 has received particular attention since it inhibits axonal regeneration after spinal cord injury in a Rho A dependent manner while inhibiting leucine rich repeat and immunoglobulin-like domain-containing protein 1(LINGO-1) disinhibits neuron outgrowth. Furthermore, LINGO-1 suppresses oligodendrocyte precursor cell maturation and myelin production. Inhibiting the action of LINGO-1 encourages remyelination both in vitro and in vivo. Accordingly, LINGO-1 antagonists show promise as therapies for demyelinating diseases. An analogous protein to LINGO-1, amphoterin-induced gene and open reading frame-3(AMIGO3), exerts the same inhibitory effect on the axonal outgrowth of central nervous system neurons, as well as interacting with the same receptors as LINGO-1. However, AMIGO3 is upregulated more rapidly after spinal cord injury than LINGO-1. We speculate that AMIGO3 has a similar inhibitory effect on oligodendrocyte precursor cell maturation and myelin production as with axogenesis. Therefore, inhibiting AMIGO3 will likely encourage central nervous system axonal regeneration as well as the production of myelin from local oligodendrocyte precursor cell, thus providing a promising therapeutic target and an area for future investigation.Simon Foale Martin Berry Ann Logan Daniel Fulton Zubair Ahmed 2017Neural Regeneration Research2017,12,8:1
13Selenocysteine incorporation in eukaryotes:insights into mechanism and effeciency from sequence,structure and spacing proximity studies of the type 1 deiodinase SECIS element显示文摘Martin GW3rd Harney JW Berry MJ 1996RNA1996,2,2:1
14Eye drop delivery of pigment epithelium-derived factor-34 promotes retinal ganglion cell neuroprotection and axon regeneration显示文摘Vasanthy Vigneswara Maryam Esmaeili Louise Deer Martin Berry Ann Logan Zubair Ahmed 2015Molecular and Cellular Neuroscience2015,,:1
15Phase 2 comparison of a novel ammonia scavenging agent with sodium phenylbutyrate in patients with urea cycle disorders: Safety, pharmacokinetics and ammonia control显示文摘Brendan Lee William Rhead George A. Diaz Bruce F. Scharschmidt Asad Mian Oleg Shchelochkov J.F. Marier Martin Beliveau Joseph Mauney Klara Dickinson Antonia Martinez Sharron Gargosky Masoud Mokhtarani Susan A. Berry 2010Molecular Genetics and Metabolism2010,,3:1
16Preparation and evaluation of the in vitro drug release properties and mucoadhesion of novel microsphere of hyaluronic acid and chitosan显示文摘Lim ST Martin GP Berry DJ 2000J Controlled Release2000,66,23:1
17Preparation and evaluation of the in vitro drug release properties and mucoadhesion of novel microspheres of hyaluronic acid and chitosan显示文摘Lira ST Martin GP Berry DJ 2000J Control Release2000,66,23:1
18Preparation and evaluation of the in vitro drug release properties and mucoadhesion of novel microsphere of hyaluronic acid and chitosan显示文摘Lim ST Martin GP Berry DJ 2000J Controlled Release2000,66,23:1
19Efficacy and tolerability of concurrent weekly low dose cisplatin during radiation treatment of localised muscle invasive bladder transitional cell carcinoma: A report of two sequential Phase II studies from the Trans Tasman Radiation Oncology Group显示文摘Nirdosh Kumar Gogna John H.L. Matthews Sandra L. Turner Heidi Mameghan Gillian M. Duchesne Nigel Spry Martin P. Berry Jacqui Keller Lee Tripcony 2006Radiotherapy and Oncology2006,,1:1
20Targeting adenoviral transgene expression to neurons显示文摘Karen Sims Zubair Ahmed Ana Maria Gonzalez Martin L. Read Lisa Cooper-Charles Martin Berry Ann Logan 2008Molecular and Cellular Neuroscience2008,,3:1
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