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| 1 | Usefulness of endoscopic ultrasonography in preoperative TNM staging of gastric cancer显示文摘瞄准:在胃的癌症的外科手术前的 TNM 阶段评估内视镜的 ultrasonography (EUS ) 的价值。方法:有胃的癌症(12 早阶段和 29 晚期) 的 41 个病人由外科手术前地根据国际联合 Contrele 癌症(UICC ) 的 TNM (1997 ) 分类与 EUS 评估的 esophagogastroduodenoscopy 和活体检视证明了。有即时超声成像的 Pentax EG-3630U/Hitachi EUB-525 回响内诊镜线性扫描变换器(7.5 和 5.0 MHz ) 和 Doppler 信息在当前的学习被使用。为侵略(T 阶段) 的肿瘤深度的 EUS 阶段过程根据胃的墙的广泛地接受的五层的结构被执行。所有病人经历了外科。为胃的癌症的 TNM 阶段的 EUS 的诊断精确性被把外科手术前的 EUS 与随后的手术后的组织病理学说的调查结果作比较决定。结果:在侵略的癌症深度的外科手术前的决心的 EUS 的全面诊断精确性是 68.3%(41/28 ) 并且 83.3%(12/10 ) , 60%(20/12 ) , 100%(5/5 ) , 25%(4/1 ) 为 T1, T2, T3,和 T4 分别地。为 overs 标注并且 unders 标注的率是 24.4%(41/10 ) ,并且 7.3%(41/3 ) 分别地。EUS 趋于到在阶段 T 标准,和 main 上,为标注的 overs 的原因由于仙子胃的墙正在变厚在胃的某些区域的 serosal 层的焦点的煽动性的变化,和缺席。变形淋巴节点参与的诊断精确性或 EUS 的 N 阶段为 N0 是 100%(17/17 ) 并且 41.7%(24/10 ) 为 N+ ,分别地并且 66%(41/27 ) 外套。变形淋巴结误诊与把煽动性的淋巴节点与恶意的淋巴节点区分开来的困难有关,它模仿类似的回响特征。在胃的肿瘤的占优势的地点和分发在窦(20 个病人) ,并且更小的弯曲(17 个病人) 分别地。三个盒子是被发现通过手术 unresectable (T4 N+) ,并且当是正确地由 EUS 诊断了,包括了。结论:EUS 是为为 T 和 N 标准的胃的癌症的外科手术前的阶段的一个有用诊断方法。然而,恶意的淋巴节点的 EUS 评估仍然是不能令人满意的。 | Tumur Tsendsuren Sun-Ming Jun Xu-Hui Mian | 2006 | World Journal of Gastroenterology2006，12，1： | 88 |
| 2 | Modeling and Backstepping-based Nonlinear Control Strategy for a 6 DOF Quadrotor Helicopter显示文摘In this article,a nonlinear model of an underactuated six degrees of freedom (6 DOF) quadrotor helicopter is derived on the basis of the Newton-Euler formalism. The derivation comprises determining equations of the motion of the quadrotor in three dimensions and approximating the actuation forces through the modeling of aerodynamic coefficients and electric motor dynamics. The derived model composed of translational and rotational subsystems is dynamically unstable,so a sequential nonlinear control strategy is used. The con-trol strategy includes feedback linearization coupled with a PD controller for the translational subsystem and a backstepping-based PID nonlinear controller for the rotational subsystem of the quadrotor. The performances of the nonlinear control method are evaluated by nonlinear simulation and the results demonstrate the effectiveness of the proposed control strategy for the quadrotor helicopter in quasi-stationary flights. | Ashfaq Ahmad Mian | 2008 | Chinese Journal of Aeronautics2008，21，3： | 54 |
| 3 | Involvement of RhoA/ROCK in myocardial fibrosis in a rat model of type 2 diabetes显示文摘瞄准: 调查 RhoA/Rho kinase (岩石) 的激活是否在糖尿病的心涉及心肌的纤维变性。 | Hong ZHOU Yong-jun LI Mian WANG Li-hui ZHANG Zhan-sheng ZHAO Feng-ling MENG Yong-gui DENG Rui-ying WANG | 2011 | Acta Pharmacologica Sinica2011，32，8： | 32 |
| 4 | Clinical significance of dynamic detection for serum levels of MCP-1,TNF-α and IL-8 in patients with acute pancreatitis显示文摘Objective:To observe dynamic changes of levels of monocyte chemotactic protein-1(MCP-1),tumor necrosis factor-α(TNF-α) and interleukin-8(IL-8) in patients with acute pancreatitis and to investigate its evaluation value on the severity of acute pancreatitis.Methods:A total of 109 patients with acute pancreatitis admitted were divided into mild acute pancreatitis group(MAP group,42 cases),moderately severe acute pancreatitis(MSAP group,35 cases)and severe acute pancreatitis(SAP group,32 cases).ELISA was used to detect the serum levels of MCP-1,TNF-α and IL-8 of patients at day 1,day 4 and day 7 of admission to hospital.Results:The serum levels of MCP-1,TNF-α and IL-8 from MAP group,MSAP group and SAP group at day 1 of admission to hospital all significantly increased.There was a significant difference between MAP group and control group,MSAP group and MAP group,SAP group and MSAP group(P<0.05).The serum concentrations of IL-8 from MASP group and SAP group obviously increased at day 1,and there was significant difference between MASP group and MAP group,SAP group and MSAP group(P<0.05),while the difference between MAP group and control group was not obvious(P>0.05);The serum concentrations of MCP-1,TNF-α and IL-8 from MAP group all reached the highest level at day 4,which were significantly higher than the detection levels at day 1.In MSAP group and SAP group,the serum concentrations of MCP-1,TNF-α and IL-8 were the highest at day 1,which were significantly higher than the detection levels at day 4 and 7.At each detecting timing,the serum concentrations of MCP-1,TNF-α and IL-8 from MSAP group and SAP group were all higher than those of MAP group and MSAP group,respectively.Conclusions:The dynamic changes of serum levels of MCP-1,TNF-α and IL-8 in patients with acute pancreatitis have their rules,and the change rule of MAP group was different with that of MSAP and SAP group,which showed the reference value for the diagnosis and illness severity evaluation of acute pancreatitis. | Yuan-Zheng Yang Ying Xiang Mian Chen Li-Na Xian Xiao-Yan Deng | 2016 | Asian Pacific Journal of Tropical Medicine2016，9，11： | 33 |
| 5 | History of the temperature-dependence of susceptibility and its implications: Preliminary results along an E-W transect of the Chinese Loess Plateau显示文摘An investigation of rock magnetic properties using the temperature-dependence ofsusceptibility (TDS) and the coercivity of different IRM components was conducted on samples ofthe Malan loess (L1) and the last interglacial soil (S1) along an E-W transect of the Chinese LoessPlateau. We find that the behavior of the TDS is useful in identifying maghemite (γ-Fe2O3) in bothloess and paleosol, and that it can be used as a new proxy of the degree of pedogenesis, which isclosely linked to climatic conditions. Based on results from the TDS, we conclude that (1) thedetrital magnetite grains predominate in the L1 unit to the west of Liupan Mts, where theweathering and pedogenetic processes were weakest; (2) a comparable degree of pedogenesisexists in the L1 at the east of the Liupan Mts and the S1 at the west of the Liupan Mts; (3) a higherconcentration of maghemite is found in the S1 unit at the eastern sections, suggesting that the localclimate was warmer and more humid in this interval. In addition, we propose that TDSmeasurements can be used as a rapid means of determining the reliability of the paleomagneticsecular variation (PSV) record in loess/poleoso/sequenees. | ZHU Rixiang LIN Mian PAN Yongxin 1) Institute of Geophysics. Chinese Academy of Sciences. Beijing 100101 2) Institute of Mechanism. Chinese Academy of Sciences, Beijing 100080 | 1999 | Chinese Science Bulletin1999，44，S1： | 24 |
| 6 | Complex Regulation of Plant Phosphate Transporters and the Gap between Molecular Mechanisms and Practical Application: What Is Missing?显示文摘自从编码高亲密关系的磷酸盐 transporter (磅) 的基因的第一份报告,现在是几乎 25 年, PHO84,在里面酵母。从那以后,与磷酸盐(Pi ) 编码蛋白质的越来越多的酵母 PHO84 相当或相同的事物以及另外的基因搬运活动在多样的植物种类被识别了并且机能上地描绘了。大进步在译解也被取得了位于这些基因和他们的产品的丰富或活动的规定下面的分子的机制。规章的基因在不同层次通过许多磅的直接或间接的规定通常影响植物 Pi 动态平衡。然而,很少为与高磷使用效率(PUE ) 开发遗传上修改的庄稼在磅的使用被完成了。这可能是在 Pi 运输从磅的角色的知识的根围和缺乏过分强调 Piuptake 并且在被要求优化 PUE 的植物以内再循环的后果。这里,我们主要集中了于与 Pi 运输活动和新兴的 understandingof 编码蛋白质的基因他们的 regulationat transcriptional, post-transcriptional,翻译,并且 translational 以后层次。另外,我们建议为在改善的磅的有效使用的潜在的策略种生长和开发。 | Mian Gu Aiqun Chen Shubin Sun Guohua Xu | 2016 | Molecular Plant2016，9，3： | 22 |
| 7 | Combined APACH Ⅱ score and arterial blood lactate clearance rate to predict the prognosis of ARDS patients显示文摘Objective:To explore the easily applicable indicators of practical value to evaluate the prognosis of acute respiratory distress syndrome(ARDS).Methods:Blood and biochemical tests and bloodgas analyses were performed upon entry into the ICUs,12 h,24 h,48 h and 72 h after that in 72 ARDS patients(who were admitted to the ICUs of our hospital from January 2000 to December 2009).Then APACHEⅡscores were achieved by combining relevant physiological parameters and laboratory results.Results:There was a statistical difference between the death group and survival group at different time points upon entering the ICUs in terms of APACHEⅡscore, alveolar-arterial oxygen difference and arterial blood lactate clearance rate.PaO2/FiO2 values were recorded to be statistically different between the death group and survival group 24 h,48 h and 72 h,respectively after entry into the ICUs.In addition,registered linear regression existed between APACHEⅡscore,alveolar-arterial oxygen difference or PaO2/FiO2 value and time. APACHEⅡscore 24 h and 72 h after entering ICUs predicted mortality with an area under the ROC curve(AUC) standing respectively at 0.919 and 0.9SS.Arterial blood lactate clearance rate 12 h, 24 h,48 h and 72 h after entering ICUs predicted mortality with an area under the ROC curve (AUC) at 0.918,0.918,0.909 and 0.991,respectively.Conclusions:APACHEⅡscore applied in combination with arterial blood lactate clearance rate is of clinical significance in assessing the prognosis of ARDS patients. | Wen-Hui Wu Yuan-Yuan Niu Chang-Ran Zhang Long-Bin Xiao Hui-Shao Ye De-Mao Pan Mian Zeng | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，8： | 21 |
| 8 | Fasudil hydrochloride hydrate, a Rho-kinase inhibitor, ameliorates hepatic fibrosis in rats with type 2 diabetes显示文摘 | Zhou Hong Fang Caixia Zhang Lihui Deng Yonggui Wang Mian Meng Fengling | 2014 | Chinese Medical Journal2014，，2： | 20 |
| 9 | 利用接收函数研究六盘山地区地壳上地幔结构特征显示文摘利用六盘山地区宽频带流动地震台阵的远震体波记录,采用接收函数方法研究台阵下方的地壳上地幔结构,并采用接收函数振幅加权叠加方法对这一地区平均地壳厚度和泊松比进行估算.研究结果显示,青藏高原东北缘和鄂尔多斯的接触过渡带接收函数震相复杂,地壳变形强烈,青藏高原东北缘地壳平均厚度约为51.5km,六盘山下方地壳厚度在53.5km,鄂尔多斯西南缘地壳平均厚度约为50km,整个莫霍面呈下凹状.泊松比计算结果显示,六盘山东侧和西侧地壳泊松比值在正常范围内(0.25~0.26),六盘山下方的地壳泊松比值偏高(0.27~0.29),推测与地壳中存在部分熔融.泊松比值的横向变化,指示测线范围地壳物质组成和力学性质存在横向差异,反映在欧亚板块与印度板块碰撞作用影响下青藏高原下地壳物质存在向北东方向的流动. | 童蔚蔚 王良书 米宁 徐鸣洁 李华 于大勇 李成 刘绍文 Mian Liu Eric Sandvol | 2007 | 中国科学(D辑)2007，37，A01： | 19 |
| 10 | 大陆内部长余震序列及其对地震风险评估的启示显示文摘板块构造学说的最有力的特征之一,是已知的板块运动让我们对板块边界未来大地震的发震位置和平均复发间隔有更清晰的认识。然而,板块构造学说却不能预测板块内的地震何时何地发生,因为理想的板块内部是不会变形的。因此,板块内部的地震风险评估过于依靠如下假设:从有限的历史记录中得到的小地震发震位置能够反映出连续变形的地区,而变形将诱发未来大地震[1]。然而,本文将要说明的是,最近许多这样的小地震很可能是几百年前发生过的大地震的余震。文中将给出一个简单的模型,并由此模型得出:余震序列的长度和断层加载速率呈反比关系。发生在缓慢变形的大陆内部的余震序列,其持续时间与在快速加载的板块边界所观测到的典型的10年尺度余震序列相比要长得多。因为这些预测与观测结果相符,所以将大陆内部地震看作稳态地震活动的一般做法高估了目前地震活跃地区的地震危险性,而低估了其他地区的地震风险。 | Seth Stein Mian Liu 刘杨(译) 朱守彪(校) | 2009 | 国际地震动态2009，，12： | 19 |
| 11 | Mechanical properties of hepatocellular carcinoma cells显示文摘AIM: To study the viscoelastic properties of humanhepatocytss and helatocellulsr carcinoma (HCC) cellsunder cytoslelstal perturbation, and to further to study theviscoelastic properties and the adhesive properties of mousehepatorna cells (HTC) in different cell cycls.METHODS: Micropipette aspiration technique was adopted tomeasure viscoelastic coefficients and adhesion force tocollagen coated surface ofthe cells. Three kinds ofcytoskeleton perturbing agents, colchiclnes (Col),cytochalssin D (CD) and vinblastine (VBL), were used totreat HCC cells and hepatocytes and the effects of thesetreatent on cell viscoelastic coefficients were investigated.The experimental results were analyzed with a thres-elsmentstandard linear solid. Further, the viscoelastic properties ofHTC cells and the adhesion force of different cycle HTC cellswere also investigated. The synchronous G1 and S phasecells were achieved through thymine-2-desoryriboside andcolchicines sequential blockage method and thymine-2-desoryriboside blockage method respectively.RESULTS: The elastic coefficients, but not viscouscoefficient of HCC cells (k1 = 103.6± 12.6N.m-2, k2 =42.5±10.4N. m-2, μ = 4.5 ± 1.9Pa. s), were significantly higherthan the corresponding value for hepatocytes (K1 = 87.5 ±12.1N.m-2, k2 =33.3± 10.3N.m-2, μ=5.9±3.0Pa. s, P<0.01). Upon treatment with CD, the viscoelastic coefficients ofboth hepotocytes and HCC cells decreased consistently,with magnitudes for the decrease in elastic coefficients ofHCC cells (k1: 68.7 N.m-2 to 81.7N.m-2, 66.3 % to 78.9 %;k2: 34.5 N.m-2 to37.1N.m-2, 81.2% to 87.3 %, P<0.001)larger than those for normal hepatocytes (k1: 42.6N. m-2 to49.8N.nt-2, 48.7% to56.9 %; k2: 17.2N.m-2 to 20.4N.m-2,51.7 % to 61.3 %, P< 0.001). There was a little decrease inthe vlscous coefficient of HCC cells (2.0 to 3.4Pa. s, 44.4 to75.6 %, P<0.001) than that for hepatocytes (3.0 to 3.gPa.s, 50.8to 66.1% P<0.001). Upon trastment with Col andVBL, the elastic coefficients of hepatocytes generallyincreased or tended to increase while those of HCC cellsdecreased. HTC cells with 72.1% ofG1 phase and 98. 9 % ofS phase were achieved and high K1, k2 value and low μvalue were the general characlteristics of HTC cells. G1phase cells had higher K1 value and lower tμ value than Sphase cells had, and G1 phase HTC cells had strongeradhesive forces [(275.9±232.8) x 10-10N] than S phase cells[(161.2± 120.4) x l0-10N, P<0.001).CONCLUSION: The difference in both the pattern and themagnitude of the effect of cytoskeletal perturbing agent onthe viscoelastic properties between HCC cells andhepatocytes may reflect differencss in the state of thecytusieleton structure and function and in the sensitivity toperturbing agent treatment between trinse two types of cells.Change in the viscoelastic properties of cancer cells mayaffect significantly tumor cell invasion and metastasis as wellas interactions between tumor cells and their micro-mechanical environments. | Gang Zhang,Department of Pathophysiology,The Third Military Medical University,Chongqing 400038,China Mian Long Zhe-Zhi Wu Wei-Qun Yu,College of Bioengineer,Chongqing university,Chongqing 400044,China | 2002 | World Journal of Gastroenterology2002，8，2： | 19 |
| 12 | Hydraulic fracture initiation theory for a horizontal well in a coal seam显示文摘A series of experiments were performed to determine rock mechanical parameters related to hydraulic fracturing of coal.The effect of confining pressure and pore pressure on the strength of coal was studied.Experimental results show that the coal seam in the study areas has a relatively low elastic modulus,high Poisson's ratio,high fragility and is easily broken and compressed.The coal seam is considered as a transversely isotropic medium,since the physical properties in the direction of bedding plane and orthogonal to the bedding plane vary markedly.Based on the generalized plane strain model,stress distribution for an arbitrarily orientated wellbore in the coal seam was determined.In a horizontal well,hydraulic fracturing was found to initiate in the coal seam mass due to tensile failure,or from cleats due to shear or tensile failure.For those coal seams with abundant natural cleats,hydraulic fracture initiation can be induced by any of these mechanisms.In this study,hydraulic fracture initiation criteria for a horizontal well in a coal seam were established. | Hou Bing Chen Mian Wang Zheng Yuan Jianbo Liu Ming | 2013 | Petroleum Science2013，10，2： | 18 |
| 13 | Regulation of the pentose phosphate pathway in cancer显示文摘精力新陈代谢是显著地,在许多人的癌症的 reprogrammed,和这些改变授与许多优点到癌症房间包括生合成的提升,快速的增长的 ATP 产生, detoxification 和支持。戊糖磷酸盐小径(PPP ) 是为葡萄糖分解代谢的一条主要小径。PPP 指导葡萄糖流动到它的氧化分支并且生产菸碱腺嘌 dinucleotide 磷酸盐(NADPH ) 的一种减少的形式,在 anabolism 的过程的必要 reductant。PPP 在由为细胞内部的反应的氧种类,减少的生合成和核糖生物的续生说的 detoxification 与不仅 ribose-5-phosphate 而且 NADPH 供应细胞调整癌症细胞生长起一个关键作用,变得清楚。因此, PPP 的改变直接作出贡献到房间增长,幸存和老朽。而且,最近的研究证明了 PPP 被众多的因素 oncogenically 或新陈代谢地调整,包括肿瘤 suppressors, oncoproteins 和细胞内部的代谢物。PPP 流动的 Dysregulation 戏剧性地影响癌症生长和幸存。因此,一更好 PPP 怎么是在癌症位于在 glycolysis 和 PPP 流动之间的平衡下面的 reprogrammed 和机制理解将在开发指向这条小径的治疗学的策略是珍贵的。 | Peng Jiang Wenjing Du Mian Wu | 2014 | Protein & Cell2014，5，8： | 17 |
| 14 | PROCESS CONTROL OF THE SAND WAVE MIGRATION IN BEIBU GULF OF THE SOUTH CHINA SEA显示文摘Based on the environment characteristics of the Beibu Gulf of South China Sea, a quasi-three-dimensional physical model is built.By coupling the bottom boundary layer with the two-dimensional tidal current field near the seabed surface, the quasi-three-dimensional hydrodynamic numerical simulation is carried out.The sand wave migration process is dealt with by coupling the hydrodynamic model with the sediment transport model.The computational results are shown to be in good agreement with the observed data, which indicates that the quasi-three-dimensional physical model can be used to simulate the migration process for small scale sand waves.Then, based on measured data, the evolution of the sand wave migration is investigated.An effective formula is developed to predict the migration rate, in which not only the effects of the environment but also the features of sand waves are considered. | LI yong LIN Mian JIANG Wen-bing FAN Feng-xin | 2011 | Journal of Hydrodynamics2011，23，4： | 15 |
| 15 | Time-sensitivity of the Kaiser effect of acoustic emission in limestone and its application to measurements of in-situ stress显示文摘Measuring in-situ stress by using the Kaiser effect in rocks has such advantages as time- effi ciency, low cost and little limitation, but the precision of the method is dependent on rock properties and delay time of the measurement. In this paper, experiments on the Kaiser effect in limestones were performed, and it was found that the limestones had good ability to retain a memory of their recent stress history and high time-sensitivity. The longer the experiment was delayed from the extraction of the stone, the larger the Felicity ratio was. As the Felicity ratio approached 1, signifi cant Kaiser effect was observed. In-situ stress should be determined by the limestone measurements when the delay time was 40-120 days. Finally, the in-situ stress in a limestone formation could be successfully measured in practice. | Jin Yan Qi Zili Chen Mian Zhang Guangqing Xu Guangqiang | 2009 | Petroleum Science2009，6，2： | 15 |
| 16 | Analysis of main controlling factors for hydrocarbon accumulation in central rift zones of the Hailar-Tamtsag Basin using a fault-caprock dual control mode显示文摘The Hailar-Tamtsag Basin is a typical rift basin where two sets of regional caprocks are developed,i.e.,mudstone caprocks(containing a small amount of tuff)developed in strong rifting stage and fault-depression stage,respectively.The caprocks have a cumulative thickness of 50-120 m in general,and a single-layer thickness of 20-50 m,interbedded with sandstone about 1-2 m thick.The large set of mudstone is distributed continuously,as pure mudstone caprock.Forty-three mudstone and tuff samples were taken to perform displacement pressure test with our independently developed displacement pressure tester.Test result shows that the displacement pressure is 0.04-10.00 MPa,which is equivalent to 0.09-20.01 MPa after being corrected to the actual burial depth.As the burial depth increases,the displacement pressure rises gradually,and is 1-10 times greater than that of oil-bearing sandstone or conglomerate reservoir at the same burial depth.The difference between displacement pressure of mudstone caprock and sandstone or conglomerate reservoir increases greatly if the burial depth exceeds 1000 m.Because of the displacement pressure difference between caprock and reservoir,the maximum height of hydrocarbon column sealed by the caprock ranges from 300 m to 2000 m,much higher than the height of the trap closure at the same burial depth.No hydrocarbons will leak through such caprocks.Analysis of the reservoir GOI,homogeneous temperature,and crude maturity of both deep and shallow reservoirs in Well Wu-20 in the Wuerxun Depression shows that Damoguaihe II Member reservoir is a secondary reservoir developed during adjustment of early reservoir.It is mainly distributed in inverted structures.Faulting is one of the main factors breaking the integrity of caprocks.Three kinds of faults are often related to the migration of hydrocarbons across regional caprocks:the first type refers to the positive inverted faults breaking the early sealing conditions and making the hydrocarbons accumulated in the early period re-migration;the second type refers to the faults with shear mudstone smear structures which lose their continuity and open vertically when the fault throws exceed 5 times of the mudstone thickness;the third type refers to the normal faults developed in the structural inversion stage,which have a typical cataclastic structure and are easy to cause vertical migration of hydrocarbons.Hydrocarbon enriched horizons of the rift basins are co-controlled by 'fault-caprock'.Specifically,95% of the geological reserve is controlled by regional caprocks,and only 5% is controlled by open faults,secondary oil/gas reservoirs are developed over regional caprocks. | FU XiaoFei CHEN Zhe YAN BaiQuan YANG Mian SUN YongHe | 2013 | Science China Earth Sciences2013，56，8： | 15 |
| 17 | Understanding hydraulic fracture propagation behavior in tight sandstone–coal interbedded formations: an experimentalinvestigation显示文摘Whether hydraulic fractures could connect multiple gas zones in the vertical plane is the key to fracturing treatment to jointly exploit coalbed methane and tight sandstone gas through integrative hydraulic fracturing in tight sandstone–coal interbedded formations. Laboratory true triaxial hydraulic fracturing experiments were conducted on layered specimens with di erent combination types of natural sandstone and coal to simulate the propagation behavior of hydraulic fractures. The effects of the fracture initiation position, fracturing fluid viscosity and injection rate were discussed. The results showed that di erent fracture morphologies could be found. When initiating from coal seams, three patterns of fracture initiation and propagation were obtained:(1) The main hydraulic fracture initiated and propagated along the natural fractures and then diverged due to the effects of in situ stress and formed secondary fractures.(2) The hydraulic fracture initiated and propagated in the direction of the maximum horizontal stress.(3) Multiple fractures initiated and propagated at the same time. With the same fracturing fluid viscosity and injection rate, the hydraulic fractures initiating in sandstones had greater chances than those in coal seams to penetrate interfaces and enter neighboring layers. Excessively small or large fracturing fluid viscosity and injection rate would do harm to the vertical extension height of the induced fracture and improvement of the stimulated reservoir volume. Compared with operation parameters(fracturing fluid viscosity and injection rate), the natural weak planes in coals were considered to be the key factor that a ected the fracture propagation path. The experimental results would make some contributions to the development of tight sandstone–coal interbedded reservoirs. | Peng Tan Yan Jin Liang Yuan Zhen-Yu Xiong Bing Hou Mian Chen Li-Ming Wan | 2019 | Petroleum Science2019，16，1： | 14 |
| 18 | Mechanomics: an emerging field between biology and biomechanics显示文摘在 vivo 各种各样的房间感觉机械刺激,它开始到机械力量的下游的发信号。当证据的身体在过去的十年在有限机械管理者的影响上被介绍时,机制 biomechanical 回答怎么全球性影响房间函数需要被探讨。复杂性和差异在 vivo,机械线索介绍不同模式砍有它的大小,持续时间,或频率的各种各样的参量的联合的流动,张力的段,或机械压缩。因此,理解被要求,从 mechanobiology 的观点,房间的机械特征是什么,机械性质为什么,并且怎么在不同房间类型之中是不同的力量是到下游地生物化学的信号的 transduced。同时,那些通常在 vivo 一起在孤立的机械刺激是的 vitro 联合了,建议是的不同因素能个别地实际上被抵销或与对方一起安排了。显然, omics 分析,系统生物学的地里的一个强大的工具,是有益的与 mechanobiology 结合然后印射它的染色体编码的机械地敏感的蛋白质和抄本完整集合。这块新出现地,也就是 mechanomics,使阐明可能在系统地变化的机械刺激下面的全球回答。这评论在 mechanomics 的相关的地里讨论当前的进展并且详细描述房间怎么察觉到外部力量并且激活生物回答。 | Jiawen Wang Dongyuan Lu Debin Mao Mian Long | 2014 | Protein & Cell2014，5，7： | 12 |
| 19 | Three New Anthraquinones from Polygonum cillinerve显示文摘Three new anthraquinones, emodin-8-β-D-(2″-O-coumarate)glucoside 1, emodin-8-β- D-(6′-O-acetyl)glucoside 2 and physicon-8-β-D-(6′-O-acetyl)glucoside 3, were isolated from the roots of Polygonum cillinerve and their structures were established by spectroscopic methods. The biological activity indicated that compound 1 had the scavenging activity on 1,1-diphenyl-2- picrylhydrazyl (DPPH) radicals (the IC50 = 8.5 μmol/L), and compound 1-3 showed no activities against HL-60 and BGC-823 cells by MTT method in vitro. | Huan Yang QI Chao Feng ZHANG Mian ZHANG Jian Qun LIU Zheng Tao WANG | 2005 | Chinese Chemical Letters2005，16，8： | 10 |
| 20 | Space experimental studies of microgravity fluid science in China显示文摘Microgravity fluid physics is an important part of microgravity sciences, which consists of simple fluids of many new systems, gas-liquid two-phase flow and heat transfer, and complex fluid mechanics. In addition to the importance of itself in sciences and applications, microgravity fluid physics closely relates to microgravity combustion, space biotechnology and space materials science, and promotes the developments of interdisciplinary fields. Many space microgravity experiments have been performed on board the recoverable satellites and space ships of China and pushed the rapid development of microgravity sciences in China. In the present paper, space experimental studies and the main results of the microgravity fluid science in China in the last 10 years or so are introduced briefly. | HU WenRui LONG Mian KANG Qi XIE JingChang HOU MeiYing ZHAO JianFu DUAN Li WANG ShuangFeng | 2009 | Chinese Science Bulletin2009，54，22： | 10 |
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