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| 1 | Grain size effect on wear resistance of WC-Co cemented carbides under different tribological conditions显示文摘The grain-size dependence of wear resistance of WC-Co cemented carbides(with mean WC grain sizes of 2.2μm,1.6μm,0.8μm and 0.4μm,respectively)was investigated under different tribological conditions.The results showed that the grain size had opposite effects on wear resistance of the cemented carbides in dry sliding wear and microabrasion tests.In the former condition,with decrease of WC grain size hence the increase of hardness,plastic deformation,fracture,fragmentation and oxidation were all mitigated,leading to a drastic decrease in the wear rate.In the latter condition,pull-out of WC grains after Co removal dominated the wear,so that the hardness of cemented carbide was not a core factor.As a result,the wear resistance of the cemented carbide generally showed a decreasing trend with decrease of the grain size,except for a slight increase in the ultrafine-grained cemented carbide.Single-pass scratching of the cemented carbides under various loads indicated the same failure mechanism as that in the sliding wear tests.Furthermore,the reasons for severe surface oxidation of the coarse-grained cemented carbides were disclosed. | Haibin Wang Mark Gee Qingfan Qiu Hannah Zhang Xuemei Liu Hongbo Nie Xiaoyan Song Zuoren Nie | 2019 | Journal of Materials Science & Technology2019，35，11： | 6 |
| 2 | RF characteristics of wireless capsule endoscopy in human body显示文摘The wireless capsule endoscope,as a small electronic device,has conquered some limitations of traditional wired diagnosing tools,such as the uncomfortableness of the cables for the patient and the inability to examine the very convoluted small intestine section.However,this technique is still encountering a lot of practical challenges and is looking for feasible improvements.This work investigates the RF performance of the wireless capsule endoscope system by studying the electromagnetic(EM) wave propagation within the human body.A wireless capsule endoscopy transmission channel model is constructed to serve the purpose of investigating signal attenuations according to the relative position between the transmitter and the receiver.Within 300-500 MHz,the S_(21) results are regular and do not display any sudden changes,which allows a suitable expression to be derived for S_(21) in terms of frequency and offset.The results provide useful information for capsule localization. | 王璟琛 王炤 Mark Leach LEE Sanghyuk Eng Gee Lim HUANG Yi | 2016 | Journal of Central South University2016，23，5： | 4 |
| 3 | Effect of graft source on unrelated donor haemopoietic stem-cell transplantation in adults with acute leukaemia: a retrospective analysis显示文摘 | Mary Eapen Vanderson Rocha Guillermo Sanz Andromachi Scaradavou Mei-Jie Zhang William Arcese Anne Sirvent Richard E Champlin Nelson Chao Adrian P Gee Luis Isola Mary J Laughlin David I Marks Samir Nabhan Annalisa Ruggeri Robert Soiffer Mary M Horowitz Eli | 2010 | Lancet Oncology2010，，7： | 2 |
| 4 | A primer on natural orifice transluminal endoscopic surgery: building a new paradigm显示文摘 | MC GEE MF ROSEN M J MARKS J | 2006 | Surg Innov2006，13，2： | 1 |
| 5 | Tribology testing of ultrafine-grained Ti processed by high-pressure torsion with subsequent coating显示文摘 | Chuan Ting Wang Nong Gao Mark G. Gee Robert J. K. Wood Terence G. Langdon | 2013 | Journal of Materials Science2013，，13： | 1 |
| 6 | A reliable method for monitoring intraabdominal pressure during natural orifice translumenal endoscopic surgery显示文摘 | MC GEE MF ROSEN M J MARKS J | 2007 | Surg Enclose2007，21，4： | 1 |
| 7 | Alanine aminotransferase is an inadequate surrogate marker for detecting lamivudine resistance显示文摘AIM: To investigate the accuracy of serum alanine aminotransferase (ALT) in diagnosing lamivudine resistance and factors that contributed to abnormal serum ALT.METHODS: This was a retrospective study of chronic hepatitis B patients on lamivudine therapy who were followed for 3-mo with liver function tests and hepatitis B virus (HBV) DNA measurement. Lamivudine resistance was defined as HBV DNA ≥ 1 log from nadir on at least 2 occasions, confirmed by genotyping. Serum ALT levels in patients with lamivudine resistance were compared to serum ALT levels in those without lamivudine resistance. RESULTS: There were 111 patients with and 117 without lamivudine resistance. The area under the receiver operating characteristic of serum ALT to diagnose lamivudine resistance was 0.645 ± 0.037. Serum ALT > 42.5 U/L gave the best diagnostic accuracy with sensitivity = 61%, specificity = 60%, positive predictive value = 60%, negative predictive value = 61%, positive likelihood ratio = 1.53 and negative likelihood ratio = 0.65 for predicting lamivudine resistance, missing 39% of resistant patients. Using other serum ALT cutoffs, diagnostic accuracy was lower. By multivariate analysis, baseline abnormal serum ALT was associated with abnormal ALT during resistance (OR = 5.98, P = 0.003), and males were associated with serum ALT flares during resistance (OR = 8.9, P = 0.016). CONCLUSION: Serum ALT is inadequate for diagnosing lamivudine resistance and has implications where viral resistance testing is suboptimal and for reimbursement of rescue therapy. | Lee Guan Lim Myat Oo Aung Bee Leng Seet Cindy Tan Yock Young Dan Yin Mei Lee Dede Selamat Sutedja Mark Fernandes Guan Huei Lee Evelyn Koay Seng Gee Lim | 2010 | World Journal of Gastroenterology2010，16，37： | 1 |
| 8 | Complete endoscopic closure of gastmtomy after natural orifice banslumenal endoscopic surgery using the NDO Plicator 显示文摘 | MC GEE MF MARKS JM ONDERS RP | 2008 | Surg Endosc2008，22，1： | 1 |
| 9 | Processing of an ultrafine-grained titanium by high-pressure torsion: An e?valuation of the wear properties with and without a TiN coating显示文摘 | Wang C T Gao N Gee Mark G | 2013 | Journal of the Mechanical Behavior of Biomed?ical Materials2013，17，： | 1 |
| 10 | A reliable method for monitoring intraabdominal pressure during natural orifice translumenal endoscopic surgery 显示文摘 | MC GEE MF ROSEN M J MARKS J | 2007 | Surgical Endoscopy2007，21，： | 1 |
| 11 | Processing of an ultrafine- grained titanium by high-pressure torsion: An evaluation of the wear properties with and without a TiN coating显示文摘 | Wang C T Gao N Gee Mark G | 2013 | Journal of Me- chanical Behavior of Biomedical Material2013，17，： | 1 |
| 12 | Risk factors for ribavirin treatment failure in Asian organ transplant recipients with chronic hepatitis E infection显示文摘BACKGROUND Hepatitis E virus(HEV)infection is a cause of chronic hepatitis in immunosuppressed patients.Sustained virologic response rates to a 12-wk course of ribavirin therapy were reported to be>70%in the West.This study describes the outcome of HEV treatment in a transplant center in Singapore.AIM To study the outcome of ribavirin treatment in a series of chronic HEV patients,and the cause of treatment failure.METHODS We studied all of the transplant recipients who were diagnosed with HEV infection between 2012 to 2015.The outcome of therapy and virologic relapse are monitored for three years after the end of therapy.RESULTS Ten transplant recipients(4 liver,5 kidney,and 1 bone marrow transplantation)with positive HEV RNA were studied.Nine patients received at least 12 wk of ribavirin therapy,and the remaining patient resolved after reducing immunosuppression therapy.Two subjects had prolonged viremia that lasted more than one year,despite continuous ribavirin therapy.Four ribavirin-treated patients(44.4%)had HEV RNA relapse after achieving a virologic response by the end of treatment.The overall failure rate is 66.7%.Being a kidney transplant recipient is the strongest risk factor for not achieving an initial sustained virologic response(0/5 treated,Chi-Square test,P<0.05).The most common side effect of ribavirin is anemia(100%)(haemoglobin reduction of 3-6.2 g/dL).Seven patients required either a blood transfusion or erythropoietin therapy.CONCLUSION The sustained virologic response rate of 12-wk ribavirin therapy for HEV infection in this Asian series was lower than expected.Kidney transplant recipients had a higher rate of treatment failure due to higher immunosuppression requirements and adverse effects. | En Xian Sarah Low Edhel Tripon Kieron Lim Poh Seng Tan How Cheng Low Yock Young Dan Yin Mei Lee Mark Muthiah Wai Mun Loo Calvin Jianyi Koh Wah Wah Phyo JunXiong Pang Seng Gee Lim Guan-Huei Lee | 2019 | World Journal of Hepatology2019，11，6： | 0 |
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