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| 1 | Clostridium difficile causing acute renal failure: Case presentation and review显示文摘AIM: Clostridium difficile infection is primarily a nosocomial infection but asymptomatic carriers of Clostridium difficile can be found in up to 5% of the general population.Ampicillin, cephalosporins and clindamycin are the antibiotics that are most frequently associated with Clostridium difficile-associated diarrhea or colitis. Little is known about acute renal failure as a consequence of Clostridium difficile-associated diarrhea.METHODS: In this case report, we describe the course of Clostridium difficile-associated diarrhea in an 82-yearold patient developing acute renal failure. Stopping the offending agent and symptomatic therapy brought a rapid improvement of diarrhea and acute renal failure, full recovery was gained 18 d after admission. In a systematic review we looked for links between the two conditions.RESULTS: The link between Clostridium difficilr-associated diarrhea and acute renal failure in our patient was most likely volume depletion. However, in experimental studies a direct influence of Clostridium difficile toxins on renal duct cells could be shown.CONCLUSION: Rapid diagnosis, nonspecific supportive treatment and specific antibiotic treatment, especially in the elderly, may lower excess mortality Clostridium difficile-associated diarrhea and renal failure being possible complications. | Jasmin Arrich Gottfried H.Sodeck Gürkan Seng(o|¨)lge Christoforos Konnaris Marcus Müllner Anton N.Laggner Hans Domanovits | 2005 | World Journal of Gastroenterology2005，11，8： | 15 |
| 2 | Matched-pair analysis of postoperative morbidity and mortality for pancreaticogastrostomy and pancreaticojejunostomy using mattress sutures in soft pancreatic tissue remnants显示文摘BACKGROUND:After pancreaticoduodenectomy,the incidence of postoperative pancreatic fistula remains high,especially in patients with 'soft' pancreatic tissue remnants.No 'gold standard' surgical technique for pancreaticoenteric anastomosis has been established.This study aimed to compare the postoperative morbidity and mortality of pancreaticogastrostomy and pancreaticojejunostomy for 'soft' pancreatic tissue remnants using modified mattress sutures.METHODS:Seventy-five patients who had undergone pancreaticogastrostomy and 75 who had undergone pancreaticojejunostomy after pancreaticoduodenectomy between 2002 and 2008 were retrospectively compared using matched-pair analysis.A modified mattress suture technique was used for the pancreaticoenteric anastomosis.Patients with an underlying 'hard' pancreatic tissue remnant,as in chronic pancreatitis,were excluded.Both groups were homogeneous for age,gender,and underlying disease.Postoperative morbidity,mortality,and preoperative and operative data were analyzed.RESULTS:There were no significant differences between the groups for the incidence of postoperative pancreatic fistula (10.7% in both).Postoperative morbidity and mortality,median operation time,median length of hospital stay,intraoperative blood loss,and the amount of intraoperatively transfused erythrocyte concentrates also did not significantly differ between the groups.Patient age >65 years (P=0.017),operation time >350minutes (P=0.001),and intraoperative transfusion of erythrocyte concentrates (P=0.038) were identified as risk factors for postoperative morbidity.CONCLUSIONS:Our results showed no significant differences between the groups in the pancreaticogastrostomy and pancreaticojejunostomy anastomosis techniques using mattress sutures for 'soft' pancreatic tissue remnants.In our experience,the mattress sutures are safe and simple to use,and pancreaticogastrostomy in particular is feasible and easy to learn,with good endoscopic accessibility to the anastomosis region.However,the location of the anastomosis and the surgical technique need to be individually evaluated to further reduce the incidence of postoperative pancreatic fistula. | Fritz Klein Marcus Bahra Matthias Glanemann Wladimir Faber Peter Warnick Andreas Andreou Safak Gül Dietmar Jacob | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，1： | 9 |
| 3 | Analysis of monocyte chemotactic protein-1 gene polymorphism in patients with spontaneous bacterial peritonitis显示文摘AIM:To investigate a genetic polymorphism of the monocyte chemotactic protein-1 (MCP-1 ) gene in patients with spontaneous bacterial peritonitis (SBP).METHODS:MCP-1 genotyping was performed in 23 patients with SBP and 83 cirrhotic control patients with non-infected ascites.RESULTS:The frequency of carriers of the G-allele was lower in SBP patients but this difference did not reach statistical significance. However,in the subgroup of patients with alcoholic cirrhosis (n=80),carriers of the G-allele were significantly less frequent in SBP-patients (38.1%) than in cirrhotic controls (67.8%,P=0.021). CONCLUSION:In patients with alcoholic liver cirrhosis,the-2518 MCP-1 genotype AA is a risk factor for the development of SBP. | Erwin Gbele Marcus Mhlbauer Hartwig Paulo Monika Johann Christin Meltzer Franz Leidl Norbert Wodarz Reiner Wiest Jrgen Schlmerich Claus Hellerbrand | 2009 | World Journal of Gastroenterology2009，15，44： | 7 |
| 4 | Preferential CTL targeting of Gag is associated with relative viral control in long-term surviving HIV-1 infected former plasma donors from China显示文摘它通常被相信细胞毒素的 T 淋巴细胞(CTL ) 玩的那 CD8 + 在限制人的免疫不全病毒类型 1 的复制(HIV-1 ) 并且在决定感染的结果,和这效果可以部分优先地取决于产品是哪个 HIV 的一个关键角色指向了。在以前的血浆施主(FPD ) 的一个队探讨在 HIV-1-specific CTL 回答和病毒复制之间的关联,天真的 FPD 与 HIV-1 clade B' 紧张感染了的 143 antiretroviral 治疗与 IFN-γ 为 HIV-1-specific CTL 回答被估计;在由使用盖住整个一致 clade B proteome 的重叠的肽(OLP ) 的单个肽水平的 Elispot 试金。由使用一个枪兵的等级关联分析,当是断然相关到 CD4 计数时,我们发现在全部的病毒特定的 CTL 活动之中的作呕特定的 CTL 回答的比例相反地与病毒的负担被相关,与与增加的病毒的负担被联系并且减少的Pol特定、Env特定的回答对比, CD4 数。另外, Vpr-specifc CTL 回答显示出类似的保护的效果与作呕回答,但是与识别的低得多的频率。显著地,我们也观察了在 HLA 之间的一个协会 --*30/B*13/Cw*06 haplotype 和可能由于的更低的病毒的负担限制了作呕特定的 CTL 回答。因此,我们的数据在疾病控制表明作呕特定的 CTL 回答的突出的角色。HLA 的优点 -- 在病毒的控制的 *30/B*13/Cw*06 haplotype 可以在学习个人与作呕特定的 CTL 回答的贡献被联系。 | Mingming Jia Kunxue Hong Jianping Chen Yuhua Ruan Zhe Wang Bing Su Guoliang Ren Xiaoqing Zhang Zhen Liu Quanbi Zhao Dan Li Hong Peng Marcus Altfeld Bruce D Walker Xu G Yu Yiming Shao | 2012 | Cell Research2012，22，5： | 3 |
| 5 | Esophageal obstruction due to enteral feed bezoar:A case report and literature review显示文摘This paper describes a rare complication of enteral feeding,esophageal obstruction due to feeding formula bezoar,and reviews the published cases. An attempt to re-insert the nasogastric tube in a chronically ventilated 80-year-old female fed via a nasogastric tube with Jevity failed. An esophagogastroduodenoscopy revealed an 18 cm-long concretion of the feeding formula,fi-lling most of the esophageal lumen,which was removed endo scopically. Forty-two cases of feeding formula esophageal bezoars have been reported in the literature. The formation of feeding formula bezoars is triggered by acidic gastroesophageal reflux. The acidic pH in the esophagus causes clotting of the casein in the formula. Predisposing factors for bezoar formation are:mechanical ventilation,supine position,neurological diseases,diabetes mellitus,hypothyroidism,obesity and history of partial gastrectomy. Diagnosis and removal of the bezoar is done endoscopically. Feeding in a semi-recumbent position,administration of prokinetic agents and proton pump inhibitors may prevent this complication. | Esther-Lee Marcus Ron Arnon Arkadiy Sheynkman Yehezkel G Caine Joseph Lysy | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，10： | 3 |
| 6 | Management of severe perioperative bleeding: Guidelines from the European Society of Anaesthesiology显示文摘 | Sibylle A. Kozek-Langenecker Arash Afshari Pierre Albaladejo Cesar Aldecoa Alvarez Santullano Edoardo De Robertis Daniela C. Filipescu Dietmar Fries Klaus G?rlinger Thorsten Haas Georgina Imberger Matthias Jacob Marcus Lancé Juan Llau Sue Mallett Jens Mei | 2013 | European Journal of Anaesthesiology2013，，6： | 3 |
| 7 | Comparison between hepaticojejunostomy and hepaticoduodenostomy after excision of choledochal cyst in children:a cohort study显示文摘Objective Hepaticojejunostomy(HJ)and hepaticoduodenostomy(HD)are commonly used biliary reconstruction techniques after choledochal cyst excision.HD has been suggested to be a more physiologic alternative during reconstruction.The objective of this study is to compare operative time,hospital stay,morbidity(leak,cholangitis,ileus,and obstruction),and mortality between HJ and HD after cyst excision.Methods This is a 14-year retrospective cohort study of pediatric patients(≤18 years old)who underwent choledochal cyst excision and subsequent biliary reconstruction at the Philippine Children’s Medical Center.Data were taken from inpatient charts,operative technique,OPD logbook,readmission,and OPD charts.results There were 122 patients:56%HD and 44%HJ.Majority were female(72%),with 1:2.6 male to female ratio.The average age was 36.1 months,with a mean follow-up of 32.8 months(range 6 months-14 years).The most common cyst was type I(87%).Operative time was longer for HJ compared with HD(321.3 vs 203.6 min;p=0.000).Hospital stay was longer with HJ compared with HD(7.7 vs 6.8 days;p=0.002).Mortality rate was low at 1.6%while morbidity was at 13.9%in both groups.Although morbidity was higher among those who underwent HD,there was no significant difference between the two procedures.Anastomotic leak(4%)and cholangitis(7.4%)were observed in HD,and ileus(7.4%)was observed in the HJ group.Conclusions In our series,HD provided less operative time and hospital stay than with HJ.We did not observe bile gastritis after HD as compared with others.It is suggested that longer follow-up is needed to confirm such findings. | Johann Paulo Suico Guzman Leandro L Resurreccion III Marcus Lester R Suntay Renato G Bernaldez | 2019 | World Journal of Pediatric Surgery2019，2，2： | 2 |
| 8 | Sixteen-slice spiral CT versus MR imaging for the assessment of left ventricular function in acute myocardial infarction显示文摘 | Andreas H. Mahnken Ralf Koos Marcus Katoh Elmar Spuentrup Petra Busch Joachim E. Wildberger Harald P. Kühl Rolf W. Günther | 2005 | European Radiology2005，，4： | 2 |
| 9 | Assessing landslide potential using GIS, soil wet -ness modeling and topographic attributes, Payene River, Idaho 显示文摘 | Lineback G M Marcus W A Aspinall R Custer S G | 2001 | Geomorphology2001，37，： | 1 |
| 10 | Refined food addiction:a classic substance use disorder 显示文摘 | IFLAND J R PREUSS H G MARCUS M T | 2009 | Med Hypothe- ses2009，72，5： | 1 |
| 11 | Effect of chemical surface heterogeneity on the adsorption mechanism of dissolved aromatics on activated carbon显示文摘 | Marcus Franz Hassan A Arafat Neville G Pinto | 2000 | Carbon2000，38，： | 1 |
| 12 | Overregularization in language acquisition显示文摘 | Marcus G F Pinker S Ullman M | 1992 | Monographs of the Society for Research in Child Development1992，57，4： | 1 |
| 13 | The mechanism of methanol to hydrocarbon catalysis 显示文摘 | HAW J F SONG W G MARCUS D M | 2003 | Acc Chem Res2003，36，： | 1 |
| 14 | Adult bone marrow stromal cells in the emhryonic brain: engraftment, migration, differentiation, and long-term survival显示文摘 | Mu-noz-Elias G Marcus A J Coyne TM | 2004 | J Neurosci2004，24，19： | 1 |
| 15 | Adipose tissue renin-angiotensin-aldoste-rone system(RAAS) and progression of insulin resistance显示文摘 | Marcus Y Shefer G Stern N | | 0，，： | 1 |
| 16 | Right ventricular dysplasia:a report of 24 adult cases显示文摘 | Marcus FI Fontaine G Guiraudon G et at | 1982 | Circulation1982，65，： | 1 |
| 17 | Right ventricular dysplasia:a report of 24 adult cases显示文摘 | Marcus FI Fontaine GH Guiraudon G | 1982 | Circulation1982，65，： | 1 |
| 18 | Adult bone marrow stromal cells in the embryonic brain:engraftment,migration,differentiation,and long-term survival显示文摘 | Munoz-Elias G Marcus AJ Coyne TM | 2004 | J Neurosci2004，24，10： | 1 |
| 19 | The mechanism of methanol to hydrocarbon catalysis显示文摘 | Haw J F Song W G Marcus D M | 2003 | Accoun Chem Res2003，36，： | 1 |
| 20 | Boundary and elastohydrodynamic lubrication studies of glycerol aqueous solutions as green lubricants 显示文摘 | Mattias G Marcus B Roland L | 2014 | Tribology International2014，69，： | 1 |
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