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| 1 | Parathyroid ultrasonography and bone metabolic profile of patients on dialysis with hyperparathyroidism显示文摘AIM To evaluate the parathyroid ultrasonography and define parameters that can predict poor response to treatment in patients with secondary hyperparathyroidism due to renal failure.METHODS This cohort study evaluated 85 patients with chronic kidney disease stage V with parathyroid hormone levels above 800 pg/mL. All patients underwent ultrasonography of the parathyroids and the following parameters were analyzed: Demographic characteristics(etiology of chronic kidney disease, gender, age, dialysis vintage, vascular access, use of vitamin D), laboratory(calcium, phosphorus, parathyroid hormone, alkaline phosphatase, bone alkaline phosphatase), and the occurrence of bone changes, cardiovascular events and death. The χ~2 test were used to compare proportions or the Fisher exact test for small sample frequencies. Student t-test was used to detect differences between the two groups regarding continuous variables.RESULTS Fifty-three patients(66.4%) had parathyroid nodules with higher levels of parathyroid hormone, calcium and phosphorus. Sixteen patients underwent parathyroidectomy and had higher levels of phosphorus and calcium × phosphorus product(P = 0.03 and P = 0.006, respectively). They also had lower mortality(32% vs 68%, P = 0.01) and lower incidence of cardiovascular or cerebrovascular events(27% vs 73%, P = 0.02). Calcium × phosphorus product above 55 mg^2/dL^2 [RR 1.48(1.06, 2.08), P = 0.03], presence of vascular calcification [1.33(1.01, 1.76), P = 0.015] and previous occurrence of vascular events [RR 2.25(1.27, 3.98), P < 0.001] were risk factors for mortality in this population. There was no association between the occurrence of nodules and mortality.CONCLUSION The identification of nodules at ultrasonography strengthens the indication for parathyroidectomy in patients with secondary hyperparathyroidism due to renal failure. | Cláudia Ribeiro Maria Goretti Moreira Guimaraes Penido Milena Maria Moreira Guimaraes Marcelo de Sousa Tavares Bruno das Neves Souza Anderson Ferreira Leite Leonardo Martins Caldeira de Deus Lucas Joséde Campos Machado | 2016 | World Journal of Nephrology2016，5，5： | 2 |
| 2 | Streptococcus agalactiae:Identification methods,antimicrobial susceptibility, and resistance genes in pregnant women显示文摘BACKGROUND Group B Streptococcus(GBS)is a normal component of the gastrointestinal and genital microbiota in humans and can lead to important infections in newborns.AIM To compare GBS isolation and identification methods as well as to assess the antibiotic susceptibility and to identify resistance genes in GBS strains from pregnant women attended in healthcare services from the city of Vitória da Conquista,in Bahia State,Brazil.METHODS From January 2017 to February 2018,vaginorectal swabs were obtained from 186 participants and the samples were seeded onto chromogenic agar for GBS before and after inoculation in selective broth.Confirmatory identification using 3 CAMP and latex tests was performed in samples with GBS-suggestive colonies.Then,disk diffusion antibiograms were performed in GBS-positive samples,and the detection of the resistance genes ermB,ermTR,mefA,and linB in the clindamycin and/or erythromycin-resistant samples was carried out.RESULTS Thirty-two samples(17.2%)were GBS-positive.The culture in chromogenic agar after sample incubation in selective broth was the most sensitive method(96.9%)for GBS detection.All isolates were susceptible to penicillin,ampicillin,cefotaxime,and vancomycin.Clindamycin resistance was observed in 6 samples(18.8%),while 8 samples(25%)were erythromycin-resistant.All erythromycin and/or clindamycin-resistant GBS strains had negative D-tests.Two strains(25%)presented an M phenotype and 6 isolates(75%)presented a cMLSB phenotype.The ermB gene was identified in 4 samples(44.4%),the mefA gene was also found in 4 samples(44.4%),the ermTR gene was identified in 1 isolate(11.1%),and the linB gene was not found in any isolate.CONCLUSION This study evidenced that the screening for SGB can be performed by means of various methods,including chromogenic media,and that the chemoprophylaxis for pregnant women who cannot use penicillin must be susceptibility-guided. | Fabrícia Almeida Fernandes Santana Tais Viana Ledo de Oliveira Marcelo Barreto de Souza Filho Lucas Santana Coelho da Silva Breno Bittencourt de Brito Fabrício Freire de Melo Cláudio Lima Souza Lucas Miranda Marques Márcio Vasconcelos Oliveira | 2020 | World Journal of Clinical Cases2020，8，18： | 2 |
| 3 | Detection of contaminants in cell cultures, sera and trypsin显示文摘 | Tatiana Flávia Pinheiro de Oliveira Ant?nio Augusto Fonseca Marcelo Fernandes Camargos Anapolino Macedo de Oliveira Ana Cláudia Pinto Cottorello Antonizete dos Reis Souza Iassudara Garcia de Almeida Marcos Bryan Heinemann | 2013 | Biologicals2013，，6： | 2 |
| 4 | Development and characterization of a tissue-engineered human oral mucosa equivalent produced in a serum-free culture system 显示文摘 | Izumi K Tefashi H Marcelo CL | 2000 | J Dent Res2000，79，3： | 1 |
| 5 | Development and characterization of a tissue-engineered human oral mucosa equivalent produced in a serum-free culture system显示文摘 | Izumi K Terashi H Marcelo CL | 2000 | J Dent Res2000，79，3： | 1 |
| 6 | Ex vivo produced human conjunctiva and oral mucosa equivalents grown in a serum-free culture system显示文摘 | Yoshizawa M Feinberg SE Marcelo CL | 2004 | J Oral Maxiilofac Surg2004，62，8： | 1 |
| 7 | Anthelmintic efficacy and management practices in sheep farms from the state of Rio de Janeiro, Brazil显示文摘 | Daniela Guedes da Cruz Letícia Oliveira da Rocha Sabrina Santos Arruda Jorge Guilherme Bergottini Palieraqui Rudymilla Cunha Cordeiro Edizio Santos Marcelo Beltr?o Molento Clóvis de Paula Santos | 2010 | Veterinary Parasitology2010，，3： | 1 |
| 8 | D-dimer Levels in Stable COPD Patients: A Case-control Study显示文摘 | Denise Rossato Silva Ana Cláudia Coelho Marcelo Basso Gazzana Sérgio Saldanha Menna Barreto Marli Maria Knorst | 2012 | COPD: Journal of Chronic Obstructive Pulmonary Disease2012，，4： | 1 |
| 9 | Cyclic AMP,glucocorticoid,and retinoid modulation of in vitro keratinocyte growth显示文摘 | Marcelo CL Tomich J | 1983 | J Invest Demmatol1983，81，1： | 1 |
| 10 | Skeletal muscle denervation increases satellite cell susceptibility to apoptosis显示文摘 | Jejurikar SS Marcelo CL Kuzon WM Jr | 2002 | Plast Reconstr Surg2002，110，1： | 1 |
| 11 | The Role of Ultrasound in the Diagnosis of Hepatic Steatosis in Morbidly Obese Patients显示文摘 | Cláudio C Mottin MD Myriam Moretto MD Alexandre V Padoin MD Aline M Swarowsky MD Marcelo G Toneto MD Luiz Glock PhD Giuseppe Repetto MD | 2004 | Obesity Surgery2004，，5： | 1 |
| 12 | Variants of Human Papillomavirus Types 53, 58 and 66 Identified in Central Brazil显示文摘 | Daniela Marreco Cerqueira Geni Noceti de Lima Camara Márcio Rojas da Cruz Evandro Oliveira Silva Marcelo de Macedo Brígido Luciano Gon?alves de Souza Carvalho Cláudia Renata Fernandes Martins | 2003 | Virus Genes2003，，1： | 1 |
| 13 | The Role of Ultrasound in the Diagnosis of Hepatic Steatosis in Morbidly Obese Patients显示文摘 | Cláudio C Mottin MD Myriam Moretto MD Alexandre V Padoin MD Aline M Swarowsky MD Marcelo G Toneto MD Luiz Glock PhD Giuseppe Repetto MD | 2004 | Obesity Surgery2004，，5： | 1 |
| 14 | Serological evidence of hepatitis E virus infection in different animal species from the Southeast of Brazil显示文摘 | Cláudia L Vitral Marcelo A Pinto Lia L Lewis-Ximenez | 2005 | Mem Inst Oswaldo Cruz Rio de Janeiro2005，100，： | 1 |
| 15 | Stratification,specializa-tion, and proliferation of primary keratinocyte cultures-evi-dence of a functioning in vitro epidermal cell systerm 显示文摘 | Marcelo CL Kim YG Kaine JL | 1978 | TheJounal of Cell Biology1978，79，2： | 1 |
| 16 | Skeletal muscle denervation increases satellite cell susceptibility to apoptosis显示文摘 | Jejurikar SS Marcelo CL Kuzon WM Jr | 2002 | Plast Reconstr Surg2002，110，1： | 1 |
| 17 | The Role of Ultrasound in the Diagnosis of Hepatic Steatosis in Morbidly Obese Patients显示文摘 | Cláudio C Mottin MD Myriam Moretto MD Alexandre V Padoin MD Aline M Swarowsky MD Marcelo G Toneto MD Luiz Glock PhD Giuseppe Repetto MD | 2004 | Obesity Surgery2004，，5： | 1 |
| 18 | Can a Strychnos species be used as antiulcer agent? Ulcer healing action from alkaloid fraction of Strychnos pseudoquina St. Hil. (Loganiaceae)显示文摘 | Flávia Bonamin Thiago Mello Moraes Hélio Kushima Marcelo Aparecido Silva Ariane Leite Rozza Cláudia Helena Pellizzon Tais Maria Bauab Lucia Regina Machado Rocha Wagner Vilegas Clélia Akiko Hiruma-Lima | 2011 | Journal of Ethnopharmacology2011，，1： | 1 |
| 19 | Development and characterization of a tissue-engineered human oral mucosa equivalent produced in a serum-free culture system显示文摘 | Izumi K Terashi H Marcelo CL et al | 2000 | J Dent Res2000，79，3： | 1 |
| 20 | Development and characterizatien of a tissue-engineered human oral mueosa equivalent produced in a serum-free culture system显示文摘 | Izumi K Terashi H Marcelo CL | 2000 | J Dent Res2000，79，3： | 1 |
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