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| 1 | Liver trauma: What current management?显示文摘Background: The liver is the most commonly damaged organ in abdominal trauma. The management of liver trauma has experienced many changes over the last two decades. Currently there is a trend toward a non-operative treatment warranted by the successful pediatric experience and better results recorded in many trauma centers worldwide. This study aimed to evaluate outcomes of operative and non-operative management of liver trauma in our institution over the last five years.Methods: The patients with a diagnosis of blunt or penetrating liver injuries, admitted and managed in our hospital from January 2012 to December 2016 were retrospectively studied. The patients were divided into 2 groups, operated and non-operated groups, according to the initial management considered appropriate at the time of patient admission. Clinical features and outcomes were analyzed.Results: The study involved 83 patients, with a mean age of 33 years and a marked male predominance(85.5%). The most common type of lesions was blunt trauma and the main cause was road traffic accidents. Sixty-eight liver injuries(81.9%) were of low severity(grades Ⅰ,Ⅱ,Ⅲ), while 15(18.1%) were of high severity(grade Ⅳ or greater). Fifty-six patients(67.5%) had multiple injuries. Surgical treatment was performed in 26(31.3%) patients. Non-operative management was undertaken in 57 cases(68.7%). The morbidity and mortality rates were clearly lower in non-operative patients compared to those in the operated group.Conclusions: Careful non-operative management is an adequate therapeutic strategy for the patients suffering from liver trauma with stable hemodynamics. Patients with complex hepatic trauma and especially those with other organ injuries continue to have significantly higher mortality. | Mohamed Tarchouli Mohamed Elabsi Noureddine Njoumi Mohamed Essarghini Mahjoub Echarrab Mohamed Rachid Chkoff | 2018 | Hepatobiliary & Pancreatic Diseases International2018，17，1： | 4 |
| 2 | Impact of the Liaison Committee of Food and Nutrition on the Quality of Patients' Meals显示文摘 | Yahia Abouda Nabiha Bouafia Mohamed Mahjoub Wadiaa Bannour Riadh Essokri Hanen Zendah Mansour N jab | 2012 | Journal of Life Sciences2012，6，8： | 1 |
| 3 | Antimicrobial and antioxidant activities of the methanolic extracts of three Salvia species from Tunisia显示文摘 | Karima Bel Hadj Salah Mohamed Ali Mahjoub Samia Ammar Laura Michel Joelle Millet-Clerc Jean Pierre Chaumont Zine Mighri Mahjoub Aouni | 2006 | Natural Product Research2006，，12： | 1 |
| 4 | Association of endothelial nitric oxide synthase Glu298Asp, 4b/a, and ?786T>C gene variants with diabetic nephropathy显示文摘 | Intissar Ezzidi Nabil Mtiraoui Manel Ben Hadj Mohamed Touhami Mahjoub Maha Kacem Wassim Y. Almawi | 2008 | Journal of Diabetes and Its Complications2008，，5： | 1 |
| 5 | Thymoquinone, the Nigella sativa Bioactive Compound, Prevents Circulatory Oxidative Stress Caused by 1,2-Dimethylhydrazine in Erythrocyte during Colon Postinitiation Carcinogenesis显示文摘 | Hanene Jrah Harzallah Rahma Grayaa Wafa Kharoubi Aya Maaloul Mohamed Hammami Touhami Mahjoub Ersin Fadillioglu | 2012 | Oxidative Medicine and Cellular Longevity2012，，： | 1 |
| 6 | Almitrine for COVID-19 critically ill patients – a vascular therapy for a pulmonary vascular disease: Three case reports显示文摘BACKGROUND Several reports with clinical,histological and imaging data have observed the involvement of lung vascular function to explain the severe hypoxemia in coronavirus disease 2019(COVID-19)patients.It has been hypothesized that an increased pulmonary blood flow associated with an impairment of hypoxic pulmonary vasoconstriction is responsible for an intrapulmonary shunt.COVID-19 may lead to refractory hypoxemia(PaO_(2)/FiO_(2) ratio below 100 mmHg)despite mechanical ventilation and prone positioning.We hypothesized that the use of a pulmonary vasoconstrictor may help decrease the shunt and thus enhance oxygenation.CASE SUMMARY We report our experience with three patients with refractory hypoxemia treated with almitrine to enhance oxygenation.Low dose almitrine(Vectarion®;Servier,Suresnes,France)was started at an infusion rate of 4μg×kg/min on a central line.The PaO_(2)/FiO_(2) ratio and total respiratory system compliance during almitrine infusion were measured.For the three patients,the PaO_(2)/FiO_(2) ratio time-course showed a dramatic increase whereas total respiratory system compliance was unchanged.The three patients were discharged from the intensive care unit.The intensive care unit length of stay for patient 1,patient 2 and patient 3 was 30 d,32 d and 31 d,respectively.Weaning from mechanical ventilation was performed 13 d,18 d and 15 d after almitrine infusion for patient 1,2 and 3,respectively.We found no deleterious effects on the right ventricular function,which was similar to previous studies on almitrine safety.CONCLUSION Almitrine may be effective and safe to enhance oxygenation in coronavirus disease 2019 patients.Further controlled studies are required. | Pierre Huette Osama Abou Arab Vincent Jounieaux Mathieu Guilbart Mohamed Belhout Guillaume Haye HervéDupont Christophe Beyls Yazine Mahjoub | 2021 | World Journal of Clinical Cases2021，9，14： | 0 |
| 7 | A hydromechanical approach for anisotropic elasto-viscoplastic geomaterials:Application to underground excavations in sedimentary rocks显示文摘To better describe excavation operations in deep geological formations,several aspects should be considered,especially the material anisotropy,time-dependent behavior,and hydromechanical coupling.In the present paper,a hydromechanical model based on the framework of continuous porous media was proposed.The mechanical elasto-viscoplastic constitutive model accounted for the material elastic and non-elastic anisotropies,using a transformation between the real transversely isotropic material and a fictitious isotropic material.Considering the hydraulic behavior,the permeability was expressed as a function of the volumetric viscoplastic strain.The model was applied to a case study of two tunnel excavations in an anisotropic rock under an initial anisotropic stress state.The results of the numerical simulations using a finite element code were in good agreement with the field convergence and permeability data. | Mohamed Mahjoub Ahmed Rouabhi | 2019 | Underground Space2019，4，2： | 0 |
| 8 | Evaluation of Risk Management of Foodborne Infection in Hospital显示文摘 | Abouda Yahia Mahjoub Mohamed Bouafia Nabiha Bouriga Rym Njah Mansour | 2014 | Journal of Life Sciences2014，8，11： | 0 |
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