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| 1 | Application of Stool-PCR test for diagnosis of Helicobacter pylori infection in children显示文摘AIM:To evaluate the usefulness of stool-PCR test for diagnosis of Helicobacter pylori(H pylori)infection in pediatric populations. METHODS:Based on endoscopic features(including nodular gastritis,erosive duodenitis and ulcer)and/or a positive rapid urease test(RUT)obtained during endoscopy,28 children from a group of children admitted to the Children's Medical Center of Tehran for persistent upper gastrointestinal problems were selected to compare biopsy-based tests with stoolPCR.Their gastric activity and bacterial density were graded by the updated Sydney system,and their first stool after endoscopy was stored at-70℃.Biopsies were cultured on modified campy-blood agar plates and identified by gram-staining,biochemical tests,and PCR.Two methods of phenol-chloroform and boiling were used for DNA extraction from H pylori isolates. Isolation of DNA from stool was performed using a stool DNA extraction kit(Bioneer Inc,Korea).PCR was performed using primers for detection of vacA,cagA,and 16srRNA genes in both isolates and stool. RESULTS:Sixteen out of 28 child patients(57%) were classified as H pylori positive by biopsy-based tests,of which 11(39%)were also positive by stoolPCR.Sensitivity and specificity of stool-PCR was 62.5% and 92.3%respectively.H pylori was observed in histological sections for 10 out of 11 stool-positivepatients.Association was observed between higher score of H pylori in histology and positivity of stoolPCR.Also association was observed between the more severe form of gastritis and a positive stool-PCR. CONCLUSION:Association between higher score of H pylori in histology and a positive stool-PCR make it a very useful test for detection of H pylori active infection in children.We also suggest that a simple stool-PCR method can be a useful test for detection of H pylori virulence genes in stool. | Tahereh Falsafi Raha Favaedi Fatemeh Mahjoub Mehri Najafi | 2009 | World Journal of Gastroenterology2009,15,4: | 5 |
| 2 | Liver trauma: What current management?显示文摘Background: The liver is the most commonly damaged organ in abdominal trauma. The management of liver trauma has experienced many changes over the last two decades. Currently there is a trend toward a non-operative treatment warranted by the successful pediatric experience and better results recorded in many trauma centers worldwide. This study aimed to evaluate outcomes of operative and non-operative management of liver trauma in our institution over the last five years.Methods: The patients with a diagnosis of blunt or penetrating liver injuries, admitted and managed in our hospital from January 2012 to December 2016 were retrospectively studied. The patients were divided into 2 groups, operated and non-operated groups, according to the initial management considered appropriate at the time of patient admission. Clinical features and outcomes were analyzed.Results: The study involved 83 patients, with a mean age of 33 years and a marked male predominance(85.5%). The most common type of lesions was blunt trauma and the main cause was road traffic accidents. Sixty-eight liver injuries(81.9%) were of low severity(grades Ⅰ,Ⅱ,Ⅲ), while 15(18.1%) were of high severity(grade Ⅳ or greater). Fifty-six patients(67.5%) had multiple injuries. Surgical treatment was performed in 26(31.3%) patients. Non-operative management was undertaken in 57 cases(68.7%). The morbidity and mortality rates were clearly lower in non-operative patients compared to those in the operated group.Conclusions: Careful non-operative management is an adequate therapeutic strategy for the patients suffering from liver trauma with stable hemodynamics. Patients with complex hepatic trauma and especially those with other organ injuries continue to have significantly higher mortality. | Mohamed Tarchouli Mohamed Elabsi Noureddine Njoumi Mohamed Essarghini Mahjoub Echarrab Mohamed Rachid Chkoff | 2018 | Hepatobiliary & Pancreatic Diseases International2018,17,1: | 4 |
| 3 | Characterization and of Ralstonia TAL-Like DNA-Binding Specificities Effectors显示文摘从 Xanthomonas sp 的抄写像使活跃之物的受动器(故事) 。为染色体工程应用被用作可定制的 DNA 有约束力的模块。Ralstonia solanacearum 像故事的蛋白质(RTL ) 展出类似的结构的特征到故事,包括一个中央 DNA 有约束力的领域填写了 of35 氨基的酸长的重复。这里,我们描绘他们作为 transcriptional 使活跃之物在植物房间原子核, mediateDNA 绑定,和力量功能本地化的 RTL 和表演。RTL 有唯一的 DNA 有约束力的体系结构并且是 enrichedin 重复变量 di 残余(RVD ) ,它决定重复 DNA 有约束力的特性。我们决定了 DNA 有约束力的 specificitiesfor RVD 序列 ND, HN, NP,和 NT。RVD ND 调停和 C 核苷酸的高度特定的相互作用, HN interactsspecifically 与 A 和 G 核苷酸,和 NP 绑在 C, A,和 G 核苷酸。而且,我们发展了一高度为设计 RTL 受动器的 efficientrepeat 集会途径。一起拿,我们的数据证明 RTL 是是要定制为指向的 genomic 和 epigenomicmodifications 绑在选择用户的 DNA 序列的优秀选择的唯一的 DNA-targetingmodules。这些调查结果将在 pathogenicityof Ralstonia spp.Key 词有关 RTL 分子的生物学和 RTL 角色便于研究: | Lixin Li Ahmed Atef Agnieszka Piatek Zahir Ali Marek Piatek Mustapha Aouida Altanbadralt Sharakuu Ali Mahjoub Guangchao Wang Suhail Khan Nina V. Fedoroff Jian-Kang Zhu Magdy M. Mahfouz | 2013 | Molecular Plant2013,6,4: | 3 |
| 4 | Chronic exercise training versus acute endurance exercise in reducing neurotoxicity in rats exposed to lead acetate显示文摘After intraperitoneal injection of 20 mg/kg lead acetate,rats received 8 weeks of treadmill exercise (15-22 m/min,25-64 minutes) and/or treadmill exercise at 1.6 km/h until exhaustion.The markers related to neurotoxicity were measured by enzyme-linked immunosorbent assay method.8 weeks of treadmill exercise significantly increased brain-derived neurotrophic factor level in the hippocampus (P=0.04) and plasma level of total antioxidant capacity of rats exposed to lead acetate (P < 0.001),and significantly decreased plasma level of malondialdehyde (P < 0.001).Acute exercise only decreased the hippocampal malondialdehyde level (P=0.09) and increased brain-derived neurotrophic factor level in the hippocampus (P=0.66).Acute exercise also enhanced the total antioxidant capacity in rats exposed to lead acetate,insignificantly (P=0.99).These findings suggest that chronic treadmill exercise can significantly decrease neurotoxicity and alleviate oxidative stress in rats exposed to lead acetate.However,acute endurance exercise was not associated with these beneficial effects. | Mohammad Shahandeh Valiollah Dabidi Roshan Somayeh Hosseinzadeh Soleiman Mahjoub Vaginak Sarkisian | 2013 | Neural Regeneration Research2013,8,8: | 3 |
| 5 | Second-order Sliding Mode Approaches for the Control of a Class of Underactuated Systems显示文摘In this paper, first-order and second-order sliding mode controllers for underactuated manipulators are proposed. Sliding mode control(SMC) is considered as an effective tool in different studies for control systems. However, the associated chattering phenomenon degrades the system performance. To overcome this phenomenon and track a desired trajectory, a twisting, a supertwisting and a modified super-twisting algorithms are presented respectively. The stability analysis is performed using a Lyapunov function for the proposed controllers. Further, the four different controllers are compared with each other. As an illustration, an example of an inverted pendulum is considered. Simulation results are given to demonstrate the effectiveness of the proposed approaches. | Sonia Mahjoub Faical Mnif Nabil Derbel | 2015 | International Journal of Automation and computing2015,12,2: | 2 |
| 6 | lnvolvement of the Notch pathway in the regnlation of matrix metalloproteinase 13 and tile dedifferentiation of articular chondrocytes in routine carti- lage 显示文摘 | Blaise R Mahjoub M Salvat C | 2009 | Arthritis Rheum2009,60,2: | 1 |
| 7 | Extensive Dowling- Degos disease following long term PUVA therapy 显示文摘 | Khaddar RK Mahjoub WK Zaraa I | 2012 | Ann Dermatol Venereal2012,139,1: | 1 |
| 8 | Chemical composition and antibacterial activity of a hexane extract of Tunisian caprifig latex from the unripe fruit of Ficus carica显示文摘 | Houda Lazreg-Aref Massoud Mars Abdelwaheb Fekih Mahjoub Aouni Khaled Said | 2012 | Pharmaceutical Biology2012,,4: | 1 |
| 9 | Impact of the Liaison Committee of Food and Nutrition on the Quality of Patients' Meals显示文摘 | Yahia Abouda Nabiha Bouafia Mohamed Mahjoub Wadiaa Bannour Riadh Essokri Hanen Zendah Mansour N jab | 2012 | Journal of Life Sciences2012,6,8: | 1 |
| 10 | Perceptions of informed con- sent for care practices: hospitalized patients and nurses显示文摘 | Mahjoub R Rutledge D N | 2010 | Appl Nurs Res2010,24,4: | 1 |
| 11 | Chemical composition and antimicrobial activity of volatile compounds of Tamarix boveana (Tamaricaceae) 显示文摘 | Saidana D MahJoub MA Boussaada O | 2008 | Microbiol Res2008,163,4: | 1 |
| 12 | Ouarda F, Association of ACE I/D polymorphism in Tunisian patients with dilated cardiomyopathy显示文摘 | Mahjoub S Mehri S Bousaada R | 2010 | Renin Angiotensin Aldosterone Syst2010,11,3: | 1 |
| 13 | Misfit strain film thickness phase diagrams and related electrome- chanical properties of epitaxial ultra-thin lead zirconate titanate films显示文摘 | Qiu Q Y Mahjoub R Alpay S P | 2010 | Acta Mater2010,58,: | 1 |
| 14 | Investigation of phase transformations and photocatalytic properties of sol-gel prepared nanostructured Zn O/Ti O2composites显示文摘 | Janitabar-Darzi S Mahjoub A R | 2009 | Journal of Alloys and Compounds2009,486,12: | 1 |
| 15 | Laparoscopy versus laparotomy management of tubal pregnancy 显示文摘 | Saleh AM Mahjoub MM E1-Kurdy AM | 2001 | Saudi Med J2001,22,9: | 1 |
| 16 | Caught Nek-ing:cilia and centrioles显示文摘 | Quarmby LM Mahjoub MR | 2005 | J Cell Sci2005,118,22: | 1 |
| 17 | Renin angiotensin system polymorphisms in relation to hypertension status and obesity in a tunisian population显示文摘 | Mehri S Mahjoub S Hammami S | 2012 | Mol Biol Rep2012,39,4: | 1 |
| 18 | Aldosterone synthase gene(CYP11B2) promoter polymorphism as a risk factor forischaemicstroke in Tunisian Arabs 显示文摘 | Saidi S Mahjoub T Almawi WY | 2010 | J Renin AngiotensinAldosterone Syst2010,11,3: | 1 |
| 19 | Detection of Epstein Barr Virus by Chromogenic In Situ Hybridization in cases of extra-hepatic biliary atresia显示文摘 | Mahjoub F Shahsiah R Ardalan FA | 2008 | Diagn Pathol2008,3,: | 1 |
| 20 | L p‐ PLA 2 is associated with structural valve degeneration of bioprostheses显示文摘 | Ablajan Mahmut Ha?fa Mahjoub Marie‐Chloé Boulanger Dominique Fournier Jean‐Pierre Després Philippe Pibarot Patrick Mathieu | 2014 | Eur J Clin Invest2014,,2: | 1 |