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| 1 | Blood flow restriction in human skeletal muscle during rest periods after high-load resistance training down-regulates miR-206 and induces Pax7显示文摘Backgroud:Blood flow re striction(BFR) with low-intensity re sistance training has been shown to result in hypertrophy of skeletal muscle.In this study,we tested the hypothesis that BFR during the rest periods between acute,high-intensity resistance exercise sessions(70% of 1 repetition maximum,7 sets with 10 repetitions) enhances the effects of the resistance training.Methods:A total of 7 healthy young men performed squats,and between sets BFR was carried out on one leg while the other leg served as a control.Because BFR was applied during rest periods,even severe occlusion pressure(approximately 230 mmHg),which almost completely blocked blood flow,was well-tolerated by the participants.Five muscle-specific microRNAs were measured from the biopsy samples,which were taken 2 h after the acute training.Results:Doppler data showed that the pattern of blood flow recovery changed significantly between the first and last BFR.microRNA-206 levels significantly decreased in the BFR leg compared to the control.The mRNA levels of RAC-β serine/threonine-protein kinase v22,nuclear re spiratory factor 1,vascular endothelial growth factor,lupus Ku autoantigen protein p70 genes(p <0.05),and paired box 7(p <0.01) increased in the BFR leg.The protein levels of paired box 7,nuclear respiratory factor 1,and peroxisome proliferator-activated receptor y coactivator 1α did not differ between the BFR leg and the control leg.Conclusion:BFR,during the rest periods of high-load resistance training,could lead to mRNA elevation of those proteins that regulate angiogenesis,mitochondrial biogenesis,and muscle hypertrophy and repair.However,BFR also can cause DNA damage,judging from the increase in mRNA levels of lupus Ku autoantigen protein p70. | Ferenc Torma Zoltan Gombos Marcell Fridvalszki Gergely Langmar Zsofia Tarcza Bela Merkely Hisashi Naito Noriko Ichinoseki-Sekine Masaki Takeda Zsolt Murlasits Peter Osvath Zsolt Radak | 2021 | Journal of Sport and Health Science2021，10，4： | 3 |
| 2 | Cell therapy for human ischemic heart diseases: Critical review and summary of the clinical experiences显示文摘 | Noemi Pavo Silvia Charwat Noemi Nyolczas András Jakab Zsolt Murlasits Jutta Bergler-Klein Mariam Nikfardjam Imre Benedek Teodora Benedek Imre J. Pavo Bernard J. Gersh Kurt Huber Gerald Maurer Mariann Gy?ngy?si | 2014 | Journal of Molecular and Cellular Cardiology2014，，： | 1 |
| 3 | Resistance training increase heat shock protein levels in skeletal muscle of young and old rats 显示文摘 | Murlasits Z Cutliop RG GeroniUa KB | 2006 | Exp Gerontol2006，41，： | 1 |
| 4 | Short-term exercise does not increase ER stress protein expression in cardiac muscle 显示文摘 | MURLASITS Z LEE Y POWERS S K | 2007 | Med Sci Sport Exe2007，39，9： | 1 |
| 5 | Hindlimb unloading in- creases muscle content of cytosolic but not nuclear Id2 and p53 proteins in young adult and aged rats显示文摘 | Siu PM Pistilli EE Murlasits Z | 2006 | J Appl Physiol2006，100，： | 1 |
| 6 | Ischemiareperfusioninduced cardiac injury:a brief review显示文摘 | Powers S K Murlasits Z Wu M | 2007 | Med Sci Sports Exerc2007，39，9： | 1 |
| 7 | Resistance training increase heat shock protein levels in skeletal muscle of young and old rats显示文摘 | MURLASITS Z CUTLIP R G GERONILLA K B | 2006 | Exp Gerontol2006，41，： | 1 |
| 8 | Resistance training increases heat shock protein levels in skeletal muscle of young and old rats显示文摘 | Murlasits Z Cutlip RG Geronilla KB | 2006 | Exp Gerontol2006，41，4： | 1 |
| 9 | Resistance training increases heat shock protein levels in skeletal muscle of young and old rats显示文摘 | MURLASITS Z CUTLIP RG GERONILLA KB | | 0，，： | 1 |
| 10 | Response of XIAP, ARC, and FLIP apoptotic suppressors to 8 wk of treadmill running in rat heart and skeletal muscle 显示文摘 | SIU P M BRYNER R W MURLASITS Z | 2005 | J Appl Physiol2005，99，1： | 1 |
| 11 | K Short-term exercise does not increase ER stress protein expression in cardiac muscle显示文摘 | Murlasits Z Lee Y Powers S | 2007 | Medicine and Science in Sports and Exercise2007，39，9： | 1 |
| 12 | Resistance training increases heat shock protein levels in skeletal muscle of young and old ram显示文摘 | MURLASITS Z CUTLIP RG GERONILLA KB | | 0，，04： | 1 |
| 13 | Short-term exercise does not increase ER stress protein expression in cardiac muscle显示文摘 | MURLASITS Z LEE Y POWERS SK | | 0，，09： | 1 |
| 14 | Response of XIAP, ARC, and FLIP apoptotic suppressors to 8 wk of treadmill running in rat heart and skeletal muscle 显示文摘 | Siu P M Bryner R W Murlasits Z | 2005 | J Appl Physiol2005，99，1： | 1 |
| 15 | Short-term exercise does not increase ER stress protein expression in cardiac muscle显示文摘 | Murlasits Z Lee Y Powers SK | 2007 | Med Sci Sports Exerc2007，39，9： | 1 |
| 16 | Ischemia- reperfusion - induced cardiac injury : a brief review 显示文摘 | Powers SK Murlasits Z Wu M | 2007 | Med Sci Sports Ex- erc2007，39，9： | 1 |
| 17 | Re- sistance training increase heat shock protein levels in skeletal muscle of young and old rats 显示文摘 | Murlasits Z Cutliop RG Geronilla KB | 2006 | Exp Gerontol2006，41，： | 1 |
| 18 | Short-term exercise does not increase ER stress protein expression in cardiac muscte显示文摘 | Murlasits Z Lee Y Powers S K | 2007 | Med Sci Sports Exerc2007，39，9： | 1 |
| 19 | Short-term exercise does not in- crease ER stress protein expression in cardiac muscle显示文摘 | Murlasits Z Lee Y Powers S | 2007 | Med Sci Sports Exerc2007，39，9： | 1 |
| 20 | Hindlimb unloading increases muscle content of cytosolic but not nuclear Id2 and p53 proteins in young adult and aged rats显示文摘 | Siu PM Pistil i EE Murlasits Z | | 0，，： | 1 |
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