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| 1 | 木虱啮小蜂对枸杞、枸杞木虱的行为反应显示文摘木虱啮小蜂Tetrastichussp.是枸杞木虱ParatriozasinicaYang&Li若虫外寄生蜂,是控制枸杞木虱种群数量动态的重要因子之一。为查明其寻找寄主的信息素,应用四臂嗅觉仪、培养皿两种方法测定了枸杞LyciumbarbarumL.的健康叶、虫伤叶、枸杞木虱若虫、若虫与叶复合体、卵与叶复合体和若虫分泌物等不同物质对木虱啮小蜂行为反应的影响。结果证明枸杞木虱若虫分泌物对木虱啮小蜂有明显的吸引作用,四臂嗅觉仪测定时有73%的雌蜂趋向分泌物材料区(P=0.0000)。枸杞健康叶,虫伤叶及其水、正丁烷提取物,卵与枸杞叶复合体对木虱啮小蜂无明显吸引作用。木虱若虫水提物及正丁烷提取物在培养皿中可吸引木虱啮小蜂并可引起刺探行为,但嗅觉仪测定时单独若虫并不吸引木虱啮小蜂,只有活体若虫与枸杞叶片复合体才对木虱啮小蜂有吸引作用(P=0.0004)。木虱啮小蜂通过与寄主若虫的接触,可提高其搜索效率。接触过寄主若虫的雌蜂第一次找到寄主的时间显著少于未曾接触寄主若虫的雌蜂,前者只用后者1/4的时间,说明该寄生蜂能对其寄主若虫进行学习。 | 段立清 刘宽余 Imre S.OTVOS 冯淑军 李海平 单艳敏 | 2005 | 昆虫学报2005，48，5： | 19 |
| 2 | A nuclear import inhibitory peptide ameliorates the severity of cholecystokinin-induced acute pancreatitis显示文摘AIM: To assess the effect of our novel cell-permeable nuclear factor-kappaB (NF-κB) inhibitor peptide PN50 in an experimental model of acute pancreatitis. PN50 was produced by conjugating the cell-penetrating penetratin peptide with the nuclear localization signal of the NF-κB p50 subunit.METHODS: Pancreatitis was induced in male Wistar rats by administering 2×100 μg/kg body weight of cholecystokininoctapeptide (CCK) intraperitoneally (IP) at an interval of 1 h. PN50-treated animals received 1 mg/kg of PN50 IP 30 min before or after the CCK injections. The animals were sacrificed 4 h after the first injection of CCK.RESULTS: All the examined laboratory (the pancreatic weight/body weight ratio, serum amylase activity,pancreatic levels of TNF-α and IL-6, degree of lipid peroxidation, reduced glutathione levels, NF-κB binding activity, pancreatic and lung myeloperoxidase activity) and morphological parameters of the disease were improved before and after treatment with the PN50 peptide.According to the histological findings, PN50 protected the animals against acute pancreatitis by favoring the induction of apoptotic, as opposed to necrotic acinar cell death associated with severe acute pancreatitis.CONCLUSION: Our study implies that reversible inhibitors of stress-responsive transcription factors like NF-κB might be clinically useful for the suppression of the severity of acute pancreatitis. | Tamás Letoha Csaba Somlai Tamáas Takács Annamária Szabolcs Katalin Jármay Zoltán Rakonczay Jr Péter Hegyi Ilona Varga József Kaszaki István Krizbai Imre Boros Ern(?) Duda Erzsébet Kusz Botond Penke | 2005 | World Journal of Gastroenterology2005，11，7： | 15 |
| 3 | Stem cell-derived exosomes-an emerging tool for myocardial regeneration显示文摘Cardiovascular diseases(CVDs) continue to represent the number one cause of death and disability in industrialized countries. The most severe form of CVD is acute myocardial infarction(AMI), a devastating disease associated with high mortality and disability. In a substantial proportion of patients who survive AMI, loss of functional cardiomyocytes as a result of ischaemic injury leads to ventricular failure, resulting in significant alteration to quality of life and increased mortality. Therefore, many attempts have been made in recent years to identify new tools for the regeneration of functional cardiomyocytes. Regenerative therapy currently represents the ultimate goal for restoring the function of damaged myocardium by stimulating the regeneration of the infarcted tissue or by providing cellsthat can generate new myocardial tissue to replace the damaged tissue. Stem cells(SCs) have been proposed as a viable therapy option in these cases. However, despite the great enthusiasm at the beginning of the SC era, justified by promising initial results, this therapy has failed to demonstrate a significant benefit in large clinical trials. One interesting finding of SC studies is that exosomes released by mesenchymal SCs(MSCs) are able to enhance the viability of cardiomyocytes after ischaemia/reperfusion injury, suggesting that the beneficial effects of MSCs in the recovery of functional myocardium could be related to their capacity to secrete exosomes. Ten years ago, it was discovered that exosomes have the unique property of transferring miRNA between cells, acting as miRNA nanocarriers. Therefore, exosomebased therapy has recently been proposed as an emerging tool for cardiac regeneration as an alternative to SC therapy in the post-infarction period. This review aims to discuss the emerging role of exosomes in developing innovative therapies for cardiac regeneration as well as their potential role as candidate biomarkers or for developing new diagnostic tools. | Erzsebet Lazar Theodora Benedek Szilamer Korodi Nora Rat Jocelyn Lo Imre Benedek | 2018 | World Journal of Stem Cells2018，10，8： | 12 |
| 4 | Association between autoimmune pancreatitis and systemic autoimmune diseases显示文摘AIM: To investigate the association between autoimmune pancreatitis (AIP) and systemic autoimmune diseases (SAIDs) by measurement of serum immunoglobulin G4 (IgG4). METHODS: The serum level of IgG4 was measured in 61 patients with SAIDs of different types who had not yet participated in glucocorticosteroid treatment. Patients with an elevated IgG4 level were examined by abdominal ultrasonography (US) and, in some cases, by computer tomography (CT). RESULTS: Elevated serum IgG4 levels (919 ± 996 mg/L) were detected in 17 (28%) of the 61 SAID patients. 10 patients had Sj gren's syndrome (SS) (IgG4: 590 ± 232 mg/L), 2 of them in association with Hashimoto's thyroiditis, and 7 patients (IgG4: 1388 ± 985.5 mg/L) had systemic lupus erythematosus (SLE). The IgG4 level in the SLE patients and that in patients with SS were not significantly different from that in AIP patients (783 ± 522 mg/L). Abdominal US and CT did not reveal any characteristic features of AIP among the SAID patients with an elevated IgG4 level. CONCLUSION: The serum IgG4 level may be elevated in SAIDs without the presence of AIP. The determination of serum IgG4 does not seem to be suitable for the differentiation between IgG4-related diseases and SAIDs. | Viktória Terzin Imre Fldesi László Kovács Gyula Pokorny Tibor Wittmann László Czakó | 2012 | World Journal of Gastroenterology2012，18，21： | 9 |
| 5 | Relation of the IGF/IGF1R system to autophagy in colitis and colorectal cancer显示文摘Metabolic syndrome(Met S), as a chronic inflammatory disorder has a potential role in the development of inflammatory and cancerous complications of the colonic tissue. The interaction of DNA damage and inflammation is affected by the insulin-like growth factor 1 receptor(IGF1 R) signaling pathway. The IGF1 R pathway has been reported to regulate autophagy, as well, but sometimes through a bidirectional context. Targeting the IGF1 R-autophagy crosstalk could represent a promising strategy for the development of new antiinflammatory and anticancer therapies, and may help for subjects suffering from Met S who are at increased risk of colorectal cancer. However, therapeutic responses to targeted therapies are often shortlived, since a signaling crosstalk of IGF1 R with other receptor tyrosine kinases or autophagy exists, leading to acquired cellular resistance to therapy. From a pharmacological point of view, it is attractive to speculate that synergistic benefits could be achieved by inhibition of one of the key effectors of the IGF1 R pathway, in parallel with the pharmacological stimulation of the autophagy machinery, but cautiousness is also required, because pharmacologic IGF1 R modulation can initiate additional, sometimes unfavorable biologic effects. | Ferenc Sipos Hajnal Székely Imre Dániel Kis Zsolt Tulassay Gyorgyi Muzes | 2017 | World Journal of Gastroenterology2017，23，46： | 9 |
| 6 | Seasonal variations of acute appendicitis and nonspecific abdominal pain in Finland显示文摘AIM:To investigate whether seasonal changes had an effect on the incidence of acute appendicitis(AA)or nonspecific abdominal pain(NSAP).METHODS:We carried out a national register study of all patients with a hospital discharge diagnosis of AA and acute NSAP in Finland.Data were analyzed for the whole country and correlated to seasonal and weather parameters(temperature,humidity).Moreover,additional sub-analyses were performed for five geographically different area of Finland.RESULTS:The observation period spanned 21 years,with 186558 appendectomies,of which 137528(74%)cases were reported as AA.The incidence of AA declined for 32%over the study period.The average incidence of the NSAP was 34/10000 per year.The mean annual temperature,but not relative humidity,showed clear geographical variations.The incidence of AA decreased significantly during the cold months of the year.No correlation was detected between temperature and incidence of NSAP.Humidity had a statistically significant impact on NSAP.CONCLUSION:The incidence of acute appendicitis is declining in Finland.We detected a clear seasonality in the incidence of AA and NSAP. | Imre Ilves Anne Fagerstrm Karl-Heinz Herzig Petri Juvonen Pekka Miettinen Hannu Paajanen | 2014 | World Journal of Gastroenterology2014，20，14： | 6 |
| 7 | WRKY transcription factors显示文摘 | Paul J. Rushton Imre E. Somssich Patricia Ringler Qingxi J. Shen | 2010 | Trends in Plant Science2010，，5： | 4 |
| 8 | Networks of WRKY transcription factors in defense signaling显示文摘 | Thomas Eulgem Imre E Somssich | 2007 | Current Opinion in Plant Biology2007，，4： | 4 |
| 9 | The WRKY superfamily of plant transcription factors显示文摘 | Thomas Eulgem Paul J. Rushton Silke Robatzek Imre E. Somssich | 2000 | Trends in Plant Science2000，，5： | 4 |
| 10 | 全科医学科研的范畴、研究需求和适用方法——《欧洲全科医学/家庭医学和基本医疗保健科研纲要》中文摘译显示文摘本文对《欧洲全科医学/家庭医学和基本医疗保健科研纲要》的中文译稿进行了重点摘登。该文件由欧洲全科医学科研网络制订,包括7部分内容:序言、导言、方法、结果、独立章节,讨论和启示。作为在欧洲发展全科医学科研的核心指南,该文件对欧洲的全科医学学科和科研发展产生了深远的影响。欧洲的全科医学体系和以此为基础而构建的学科理论共识与我国全科医学当前的实际情况可能更为接近。因篇幅所限,本文刊登了其中最重要,对中国研究者也最实用的5部分内容,包括:(1)导言——全科医学的核心能力/特征以及全科医学科研的意义;(2)结果——全科医学的6个核心领域(基本保健管理、'以人为本'的照护、解决具体问题的技能、综合的方法、以社区为导向、整体的方法)的科研范畴,研究需求和适用方法;(3)独立章节——如何发展基本的科研能力和避免常见的科研失误;(4)讨论——未来的全科医学科研重点;(5)启示——科学协会、研究机构、患者参与、科研工作、期刊、科研政策在发展学科方面应注重的问题。因欧洲的全科医学体制和我国较为相似,且存在一定的科研发展代差,该文件在当前阶段也可为我国全科医学研究者所用,基于全科医学学科的视角,从概念、分类学、范围和科研方法等方面,为我国全科医学科研的发展提供参照。 | Eva Hummers-Pradier Martin Beyer Patrick Chevallier Sophia Eilat-Tsanani Christos Lionis Lieve Peremans Davorina Petek Imre Rurik Jean Karl Soler Henri E.J.H.Stoffers Pinar Topsever Mehmet Ungan Paul van Royen Hanny Prick 无 | 2022 | 中国全科医学2022，25，9： | 4 |
| 11 | 世界养虾业成功的关键因素及展望显示文摘全球海捕对虾产量从1985年开始停滞不前,一直徘徊在190万t左右,然而这一期间的对虾养殖却取得了前所未有的成功,续续扩大着世界对虾市场的供给。养殖对虾产量从1982年的10万t上升到1992年的70万t,在水产养殖历史上写下了最成功的一页。80年代中期对虾养殖产量的指数增长主要得益于几项养殖技术的突破性进展(主要是苗种和饵料),但是经济和生态方面的限制接踵而至,使得增长速度在80年代末开始变慢。由于加工业和市场方面的成就使养殖对虾产量仍以稍慢的速度在增长,然而现在对虾养殖已发展到了一个关键时期。尽管对虾养殖业有捕捞业所不可企及的几项优点,但它的进一步发展还有赖于养殖技术的改进,管理水平的提高以及产品和市场的多元化发展。过去10年的经验累积已提供了足够的依据来纠正前一时期因盲目快速发展而造成的失误。 | Imre Csavas 蔡生力 张岩 于佳 | 1994 | 国外水产1994，，1： | 2 |
| 12 | Economic Assessment and Review of Waterless Fracturing Technologies in Shale Resource Development: A Case Study显示文摘Our database tracking of USA water usage per well indicates that traditionally shale operators have been using, on average 3 to 6 million gallons of water; even up to 8 million for the entire life cycle of the well based on its suitability for re-fracturing to stimulate their long and lateral horizontal wells. According to our data, sourcing, storage, transportation, treatment, and disposal of this large volume of water could account for up to 10% of overall drilling and completion costs. With increasingly stringent regulations governing the use of fresh water and growing challenges associated with storage and use of produced and flowback water in hydraulic fracturing, finding alternative sources of fracturing fluid is already a hot debate among both the scientific community and industry experts. On the other hand, waterless fracturing technology providers claim their technology can solve the concerns of water availability for shale development. This study reviews high-level technical issues and opportunities in this challenging and growing market and evaluates key economic drivers behind water management practices such as waterless fracturing technologies, based on a given shale gas play in the United States and experience gained in Canada. Water costs are analyzed under a variety of scenarios with and without the use of(fresh) water. The results are complemented by surveys from several oil and gas operators. Our economic analysis shows that fresh water usage offers the greatest economic return. In regions where water sourcing is a challenge, however, the short-term economic advantage of using non-fresh water-based fracturing outweighs the capital costs required by waterless fracturing methods. Until waterless methods are cost competitive, recycled water usage with low treatment offers a similar net present value(NPV) to that of sourcing freshwater via truck, for instance. | Iman Oraki Kohshou Reza Barati Meaghan Cassey Yorro Tim Leshchyshyn Adebola T. Adejumo Usman Ahmed Imre Kugler Murray Reynolds James McAndrew | 2017 | Journal of Earth Science2017，28，5： | 2 |
| 13 | Towards a Theoretical Framework of Autonomous Systems Underpinned by Intelligence and Systems Sciences显示文摘Autonomous systems are an emerging AI technology functioning without human intervention underpinned by the latest advances in intelligence,cognition,computer,and systems sciences.This paper explores the intelligent and mathematical foundations of autonomous systems.It focuses on structural and behavioral properties that constitute the intelligent power of autonomous systems.It explains how system intelligence aggregates from reflexive,imperative,adaptive intelligence to autonomous and cognitive intelligence.A hierarchical intelligence model(HIM)is introduced to elaborate the evolution of human and system intelligence as an inductive process.The properties of system autonomy are formally analyzed towards a wide range of applications in computational intelligence and systems engineering.Emerging paradigms of autonomous systems including brain-inspired systems,cognitive robots,and autonomous knowledge learning systems are described.Advances in autonomous systems will pave a way towards highly intelligent machines for augmenting human capabilities. | Yingxu Wang Ming Hou Konstantinos NPlataniotis Sam Kwong Henry Leung Edward Tunstel Imre JRudas Ljiljana Trajkovic | 2021 | IEEE/CAA Journal of Automatica Sinica2021，8，1： | 2 |
| 14 | WRKY transcription factors: from DNA binding towards biological function显示文摘 | Bekir ülker Imre E Somssich | 2004 | Current Opinion in Plant Biology2004，，5： | 2 |
| 15 | 应用“A”型外展支具治疗股骨头缺血性坏死疗效分析显示文摘股骨头缺血性坏死的最佳治疗方法一直存在争议。包容治疗和手术包容治疗各有利弊。近期多中心的研究结果显示对于中度的股骨头缺血性坏死病变采用股骨或骨盆截骨术其结果优于未手术的患者。但对于大龄和严重的股骨头坏死病例,其结果并不理想。 | 刘双 张立军 Sandor Kiss Tamas Terebessy Gyorgy Szoke Janos Kiss Imre Antal Miklos Szendroi | 2014 | 中国矫形外科杂志2014，22，7： | 2 |
| 16 | Inflammation and oxidative stress caused might lead to left ventricular diastolic and hypertension by nitric oxide synthase uncoupling systolic dysfunction in patients with显示文摘 | Zsuzsanna Szelenyi Adam Fazakas Gabor Szenasi Melinda KiSS Narcis Tegze Bertalan CsabaFekete Eszter Nagy Imre Bodo Balint Nagy Attila Molvarec Attila Patocs Lilla Pepo Zoltan Prohatszka Andras Vereckei | 2015 | Journal of Geriatric Cardiology2015，12，1： | 2 |
| 17 | 智能环境基于用户交互模态的情境感知服务显示文摘智能环境系统构成的复杂性和大量的情境信息增加了为用户提供和布局服务的难度。情境感知服务系统能感知系统运行和人机交互情境,根据相应的决策机制选择适当的设备为用户提供服务,从而简化环境设施的功能布局。在决策过程中引入用户交互模态信息有利于系统根据用户的交互能力和对人机界面的偏好提供服务。把情境细分为用户信息、设备信息、软件信息和环境拓扑信息,针对智能环境提出了一种基于用户交互模态的情境感知服务系统,同时详细说明了利用该技术选择服务的推理过程及其应用方法。通过智慧家庭环境中的场景案例验证了该系统的有效性。 | 王军锋 余隋怀 IMRE Horvath 王宁 | 2015 | 计算机工程与应用2015，51，19： | 2 |
| 18 | Ozone production rate and hydroearhon reactivity in 5 urban areas: a cause of high ozone concentration in Houston 显示文摘 | Kleinman L I Daum P H Imre D | 2002 | Geophysieal Researeh Letters2002，29，10： | 1 |
| 19 | Modelling of the micromorphology of the activated sludge floc:low DO,low F/M bulking显示文摘 | IMRE T ERON F | 1995 | Wat Sci Tech1995，31，2： | 1 |
| 20 | Determination of trace elements in human liver biopsy samples by ICP–MS and TXRF: hepatic steatosis and nickel accumulation显示文摘 | Imre Varga ágnes Szebeni Norbert Szoboszlai Béla Kovács | 2005 | Analytical and Bioanalytical Chemistry2005，，3： | 1 |
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