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    题名 作者 年代 出处 被引量
1Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics显示文摘交往受体的蛋白质 kinase-3 (RIP3 或 RIPK3 ) 是执行 “ 的细胞的机械的必要部分; programmed”或 “ regulated”坏死。这里,我们证明那规划坏死响应许多化学疗法的代理人被激活并且贡献导致化疗的房间死亡。然而,我们证明那 RIP3 表情经常在化学疗法的死亡期间由于它的 transcriptional 开始地点, MLKL 的这样 RIP3 依赖的激活和下游地规划的坏死附近的 genomic methylation 是在癌症房间的 silenced 大部分被镇压。不过,有 hypomethylating 代理人的治疗恢复 RIP3 表示,并且从而以一种 RIP3 依赖的方式把敏感提升到 chemotherapeutics。RIP3 表示在 85% 乳癌病人与正常织物相比在肿瘤被减少,建议那 RIP3 缺乏断然在肿瘤生长 / 发展期间被选择。因为 hypomethylating 代理人在病人是相当容忍得好的,我们建议病人们可以从收到 hypomethylating 代理人与常规 chemotherapeutics 在治疗以前导致 RIP3 表示有益于的那 RIP3 缺乏的癌症。Gi-Bang Koo Michael J Morgan Da-Gyum Lee Woo-Jung Kim Jung-Ho Yoon Ja Seung Koo Seung I1 Kim Soo Jung Kim Mi Kwon Son Soon Still Hong Jean M Mulcahy Levy Daniel A Pollyea Craig T Jordan Pearlly Yan David Frankhouser Deedra Nicolet Kati Maharry Guido Marcucci Kyeong Sook Choi Hyeseong Cho ndrew Thorbum You-Sun Kim 2015Cell Research2015,25,6:20
2Targeted next‐generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas显示文摘Eliana Amato Marco dal Molin Andrea Mafficini Jun Yu Giuseppe Malleo Borislav Rusev Matteo Fassan Davide Antonello Yoshihiko Sadakari Paola Castelli Giuseppe Zamboni Anirban Maitra Roberto Salvia Ralph H Hruban Claudio Bassi Paola Capelli Rita T Lawlor Mi 2014J. Pathol2014,,3:2
3Hematopoietic potential of stem cells isolated from murine skeletal muscle显示文摘Jackson KA Mi T Goodell MA 0,,:2
4NF-kappaB: pivotal mediator or innocent bystander in atherogenesis?显示文摘Cllins T Cybulsky MI 2001J Clin Invest2001,107,3:2
5Incipient angiogenesis in Barrett's epithelium and lymphangiogenesis in Barrett's adenocarcinoma显示文摘Auvinen MI Sihvo EI Ruohtula T 2002J Clin Oncol2002,20,13:1
6Autoantibody from women with preeclampsia induces soluble Fms -like tyrosine kinase -1 production via angiotensin type 1 receptor and calcineurinlnuclear factor of activated T -cells signaling显示文摘Zhou CC Ahmad 5 Mi T 2008Hypertension2008,51,4:1
7Cyste- inyl-leukotriene type 1 receptors transduce a critical signal for the up-regulation of eosinophilopoiesis by interleukin-13 and eotaxin in murine bone marrow 显示文摘Queto T Gaspar-Elsas MI Masid-de-Brito D 2010J Leukoc Biol2010,87,5:1
8Technical overview of compressed natural gas (CNG) as a transportation fuel显示文摘Khan MI Yasmin T Shakoor A 2015Renewable and Sus- tainable Energy Reviews2015,51,:1
9NF--kappaB: pivotal mediator or innocent bystander in atherogenesis? 显示文摘Collins T Cybulsky MI 2001J Clin Invest2001,107,3:1
10PAH emission from a gasoline-powered Engine显示文摘Mi H H Lee W J Lin T C 1996Journal of Environment Science and Health Part A-Environmental Science and Engineering1996,31,8:1
11The fibrin plate method for estima- ting fibrinolytie aetivity显示文摘Astrup T Mi~llerl:z S 1952Archi''ves of Biockemistry arzd Biopkysics1952,40,:1
12Non-Hodgkin's Lymphoma of the female urethra pressenting as a caruncle显示文摘Atalay AC Karaman MI Basak T 1998Int Urol Nephrol1998,30,5:1
13Endoscopic ultrasonography versus cholanglography for the diagnosis of choledocholithiasis显示文摘Canto MI Chak A Stellato T 1998Gastrointest Endosc1998,47,6:1
14A taxane with oral bioavailability and potent antitumor activity显示文摘Nicoletti MI Colombo T Rossi C 2000Cancer Res2000,60,15:1
15Highly crystalline montmorillonite obtained by treatment with TiCl4 agueous solutions显示文摘Yamanaka S Nishihara T Hattor Mi 1987Mater Chem Phys1987,17,:1
16Correlation between peri-infarct DC shifts and ischaemic neuronal damage in rat显示文摘MIES G IIJIMA T HOSSMANN K A 1993Neuroreport1993,4,6:1
17Fabrication and characterization of a sponge-like asymmetric chitosan membrane as a wound dressing显示文摘L Mi S S Shyu Y B Wu S T Lee 2001Biomaterials2001,22,:1
18Expression of angiotensin type 1 and 2 receptors in brain after transient middle cerebral artery occlusion in rats显示文摘Kagiyama T Kagiyama S Phillips MI 2003Regulatory Peptides2003,110,:1
19The effectiveness of team- based learning (TBL) as a new teaching approach for pharmaceu- tical care education 显示文摘Suno MI Yoshida T Koyama T 2013Yakugaku Zasshi2013,133,10:1
20Adipocyte-specific expression of murine resistin is mediated by synergism between peroxisome proliferator-activated receptorγand CCAAT/enhancer-binding proteins显示文摘Tomaru T Steger DJ Lefterova MI 2009J Biol Chem2009,284,10:1
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