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| 1 | Immunological Effects of Silica and Asbestos显示文摘Silicosis patients(SILs) and patients who have been exposed to asbestos develop not only respiratory diseases but also certain immunological disorders. In particular,SIL sometimes complicates autoimmune diseases such as systemic scleroderma,rheumatoid arthritis(known as Caplan syndrome) ,and systemic lupus erythematoses. In addition,malignant complications such as lung cancer and malignant mesothelioma often occurr in patients exposed to asbestos,and may be involved in the reduction of tumor immunity. Although silica-induced disorders of autoimmunity have been explained as adjuvant-type effects of silica,more precise analyses are needed and should reflect the recent progress in immunomolecular findings. A brief summary of our investigations related to the immunological effects of silica/asbestos is presented. Recent advances in immunomolecular studies led to detailed analyses of the immunological effects of asbestos and silica. Both affect immuno-competent cells and these effects may be associated with the pathophysiological development of complications in silicosis and asbestos-exposed patients such as the occurrence of autoimmune disorders and malignant tumors,respectively. In addition,immunological analyses may lead to the development of new clinical tools for the modification of the pathophysiological aspects of diseases such as the regulation of autoimmunity or tumor immunity using cell-mediated therapies,various cytokines,and molecule-targeting therapies. In particular,as the incidence of asbestos-related malignancies is increasing and such malignancies have been a medical and social problem since the summer of 2005 in Japan,efforts should be focused on developing a cure for these diseases to eliminate nationwide anxiety. | Takemi Otsuki Megumi Maeda Shuko Murakami Hiroaki Hayashi Yoshie Miura Masayasu Kusaka Takashi Nakano Kazuya Fukuoka Takumi Kishimoto Fuminori Hyodoh Ayako Ueki Yasumitsu Nishimura | 2007 | Cellular & Molecular Immunology2007，4，4： | 9 |
| 2 | Endoscopic transgastric drainage of a gastric wall abscess after endoscopic submucosal dissection显示文摘A 63-year-old woman was referred to our hospital for further examination because of an incidental finding of early gastric cancer.Endoscopic submucosal dissection(ESD)was successfully performed for complete resection of the tumor.On the first post-ESD day,the patient suddenly complained of abdominal pain after an episode of vomiting.Abdominal computed tomography(CT)showed delayed perforation after ESD.The patient was conservatively treated with an intravenous proton pump inhibitor and antibiotics.On the fifth post-ESD day,CT revealed a gastric wall abscess in the gastric body.Gastroscopy revealed a gastric fistula at the edge of the post-ESD ulcer,and pus was found flowing into the stomach.An intradrainage stent and an extradrainage nasocystic catheter were successfully inserted into the abscess for endoscopic transgastric drainage.After the procedure,the clinical symptoms and laboratory test results improved quickly.Two months later,a follow-up CT scan showed no collection of pus.Consequently,the intradrainage stent was removed.Although the gastric wall abscess recurred 2 wk after stent removal,it recovered soon after endoscopic transgastric drainage.Finally,after stent removal and oral antibiotic treatment for 1 mo,no recurrence of the gastric wall abscess was found. | Osamu Dohi Moyu Dohi Ken Inoue Yasuyuki Gen Masayasu Jo Kazuhiko Tokita | 2014 | World Journal of Gastroenterology2014，20，4： | 4 |
| 3 | Single-port laparoscopic hepatectomy: technique, safety, and feasibility in a clinical case series显示文摘 | Masayasu Aikawa Mitsuo Miyazawa Kojun Okamoto Yasuko Toshimitsu Katsuya Okada Yosuke Ueno Shigeki Yamaguchi Isamu Koyama | 2012 | Surgical Endoscopy2012，，6： | 3 |
| 4 | Laparoscopic partial resection for hemangioma in the third portion of the duodenum显示文摘Benign duodenal tumors are rare and less commonthan malignant tumors.Furthermore,vascular lesionsof the duodenum,including hemangiomas,are rarecauses of gastrointestinal bleeding.This report describes a case with bleeding hemangiomas in the thirdportion of the duodenum and jejunum and their successful treatment using a laparoscopic approach.Thereis no report of totally laparoscopic resection for tumorin the third portion of duodenum.After performinga laparoscopic Kocher maneuver,the location of theduodenal hemangioma was confirmed by endoscopicand laparoscopic observation.The lesion was excisedusing ultrasonic coagulating shears and the defect inthe duodenal wall was sutured laparoscopically.Thehemangioma of the jejunum was treated extracorporeally through a 3.0 cm umbilical incision.The operatingtime was 241 min and blood loss was negligible.Thepostoperative course was uneventful.For benign duodenal tumors in the third portion,if endoscopic resection is not adapted,this less invasive technique may be a standard treatment. | Shingo Kanaji Tetsu Nakamura Masayasu Nishi Masashi Yamamoto Kiyonori Kanemitu Kimihiro Yamashiita Tatsuya Imanishi Yasuo Sumi Satoshi Suzuki Kenichi Tanaka Yoshihiro Kakeji | 2014 | World Journal of Gastroenterology2014，20，34： | 2 |
| 5 | Intraperitoneal Hyperthermic Perfusion Combined with Surgery Effective for Gastric Cancer Patients with Peritoneal Seeding显示文摘 | SHIGERU FUJIMOTO RAM DHOJ SHRESTHA MASASHI KOKUBUN MASAYASU OHTA MAKOTO TAKAHASHI KOKURIKI KOBAYASHI SOHZABURO KIUCHI KATSUJI OKUI TAKEYOSHI MIYOSHI NOBORU ARIMIZU HIROYOSHI TAKAMIZAWA | 1988 | Annals of Surgery1988，，1： | 2 |
| 6 | 混合的自然的孔 transluminal 为 ileocecal 的内视镜的外科切除术显示文摘 Although laparoscopic colectomy is commonly performed around the world,an operative wound formed during the surgery is large but not sufficient enough to convert for the majority of open surgery.Thus,a certain sized skin incision is required to remove the resected colon.Here we report the case of a pure laparoscopic ileocecal resection which involves transanal specimen extraction.We present a case characterized by a laterally spreading type of tumor of the cecum.We performed a pure laparoscopic ileocecal resection and the resected specimen was removed transanally using colonoscopy.Intracorporeal functional anastomosis was then performed using a flexible linear stapling device under supporting barbed suture traction.The patient was discharged without complications on postoperative day 4.Laparoscopic colectomy performed with minimal incision could essentially increase the usage of this surgical technique.Although our method is restricted to flat or small lesions,we think it is a feasible and realistic solution for minimization of operative invasion because it involves specimen extraction through a natural orifice. | Satoru Takayama Masayasu Hara Mikinori Sato Hiromitsu Takeyama | 2012 | World Journal of Gastrointestinal Surgery2012，4，2： | 2 |
| 7 | Association of Plasma Homocysteine Concentration With Atherosclerotic Carotid Plaques and Lacunar Infarction显示文摘 | Tsutomu Sasaki Manabu Watanabe Yoji Nagai Taku Hoshi Masashi Takasawa Masaru Nukata Akihiko Taguchi Kazuo Kitagawa Naokazu Kinoshita Masayasu Matsumoto | 2002 | Stroke: Journal of the American Heart Association2002，，6： | 2 |
| 8 | Oscillatory Flow in Thermoacoustic Sound Wave Generator显示文摘在一个 thermoacoustic 声波发电机的摆动的流动被描述。thermoacoustic 声波发电机在 thermoacoustic 设备起一个重要作用。在工作液体的工作液体和栈,加速和减速之间的热交换并且粘滞在栈并且在回声试管影响的磨擦损失 thermoacoustic 声波生成器的性能。特别地,摆动的流动显著地影响在工作液体和栈之间的热交换机制。在压力和速度的时间的变化是在回声试管内的正弦曲线。流动就在试管插头后面形成一口摆动的喷气,并且在回声试管外面下游地远变得断断续续。0.63R 的无限制的修正,也就是说尽管有在试管插头外面,被速度大小证实并且流动,摆动的流动特征下游地被维持的区域可视化。另外,他们几乎等于听觉的理论结果。关键词 thermoacoustic 现象 - 声波生成器 - 摆动的流动 CLC 数字 TK11. | Masayasu HATAZAWA | 2006 | Journal of Thermal Science2006，15，1： | 2 |
| 9 | Neurogenesis by Progenitor Cells in the Ischemic Adult Rat Hippocampus显示文摘 | Yoshiki Yagita Kazuo Kitagawa Toshiho Ohtsuki Ken-ichiro Takasawa Takaki Miyata Hideyuki Okano Masatsugu Hori Masayasu Matsumoto | 2001 | Stroke: Journal of the American Heart Association2001，，8： | 2 |
| 10 | 显示文摘 | ZHAO R MASAYASU H HOLMGREN A | 2002 | Proc Nail Acad Sci USA2002，99，13： | 1 |
| 11 | Detection and evaluation of AE waves due to rock deformation显示文摘 | Tomoki Shiotani Masayasu Ohtsu | 2001 | Construct Build Mater2001，，15： | 1 |
| 12 | Chicken Ghrclin: Purification, cDNA cloning, and biological activity 显示文摘 | Hiroyuki Kaiya Serge Van Der Geyten Masayasu Kojima | 2002 | Endocrinology2002，143，9： | 1 |
| 13 | Development of a new high-frequency, high-peak current power source for high constricted arc formation 显示文摘 | Onuki J Yoshisa A Masayasu N | 2002 | Journal of Applied Physics2002，41，9： | 1 |
| 14 | Finite-difference time-domain simulation of partial discharges in a gas insulated switchgear显示文摘It is important to estimate the current magnitude and charge amount of a partial discharge (PD) in a gasinsulatedswitchgear (GIS). In this study, electromagnetic fields generated by a PD in an 84 kV-class three-phase GIS fortesting have been measured with a voltage probe installed on the outer surface of an insulation spacer of the GIS tank,and the corresponding simulations have been carried out using the three-dimensional finite-difference time-domain(FDTD) method. FDTD-computed time-domain voltages across spacers agree reasonably well with the correspondingmeasured ones, and the current magnitude of PD and its charge amount have been estimated. | Hiroki Tanaka Daiki Tanahashi Yoshihiro Baba Naoto Nagaoka Naoki Okada Hideto Ohki Masayasu Takeuchi | 2016 | High Voltage2016，1，1： | 1 |
| 15 | Perioperative intravenous flurbiprofen reduces postoperative pain after abdominal hysterectomy 显示文摘 | Masayasu Nakayama Hiromichi Ichinose Shuji Yamamoto | 2001 | Canadian Journal of Anesthesia2001，2，48： | 1 |
| 16 | 显示文摘 | Masayasu Kojima | 1999 | Nature1999，402，： | 1 |
| 17 | Antioxidant ebselen reduces oxidative damage in focal cerebral ischemia 显示文摘 | Imai H Graham DI Masayasu H | 2003 | Free Radic Biol Med2003，34，1： | 1 |
| 18 | A new scorpion polypeptide enhances the binding of radiolabeled-ryanodine on ryanodine receptor in sarcoplasmic reticulum of rabbit skeletal muscle显示文摘RYANODINE is a toxic alkaloid from the plant Ryania speciosa Vahl. It selectively binds to the Ca2+ release channel on skeletal and cardiac heavy sarcoplasmic reticulum (HSR) and has | Seiko Kawano Yoshiyuki Hirayama Masayasu Hiraoka Akihiko Kuniyasu Hitoshi Nakayama | 1997 | Chinese Science Bulletin1997，42，2： | 1 |
| 19 | Development of a new high-frequency, high-peak current power source for high constricted arc formation 显示文摘 | Jin Onuki Yoshisa Anazawa Masayasu Nihei | 2002 | Jpn J Appl Phys2002，，41： | 1 |
| 20 | A non - infantile case of desmoplastic infantile astrocytoma 显示文摘 | Masayasu Kato Hirohito Yano | 2004 | Childs Nerv Syst2004，20，： | 1 |
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