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| 1 | ABO incompatible renal transplants:Good or bad?显示文摘ABO incompatible kidney transplantation(ABOi-KT) was previously considered to be an absolute contraindication for patients with end-stage kidney disease(ESKD) due to hyperacute rejection related to blood type barrier. Since the first successful series of ABOi-KT was reported, ABOi-KT is performed increasingly all over the world. ABOi-KT has led to an expanded donor pool and reduced the number of patients with ESKD awaiting deceased kidney transplantation(KT). Intensified immunosuppression and immunological understanding has helped to shape current desensitization protocols. Consequently, in recent years, ABOi-KT outcome is comparable to ABO compatible KT(ABOc-KT). However, many questions still remain unanswered. In ABOi-KT, there is an additional residual immunological risk that maylead to allograft damage, despite using current diverse but usually intensified immunosuppressive protocols at the expense of increasing risk of infection and possibly malignancy. Notably, in ABOi-KT, desensitization and antibody reduction therapies have increased the cost of KT. Reassuringly, there has been an evolution in ABOiKT leading to a simplification of protocols over the last decade. This review provides an overview of the history, outcome, protocol, advantages and disadvantages in ABOi-KT, and focuses on whether ABOi-KT should be recommended as a therapeutic option of KT in the future. | Masaki Muramatsu Hector Daniel Gonzalez Roberto Cacciola Atsushi Aikawa Magdi M Yaqoob Carmelo Puliatti | 2014 | World Journal of Transplantation2014,4,1: | 18 |
| 2 | Immunohistochemical study on tumor angiogenic factors in non-small cell lung cancer显示文摘 | Aikawa H Takahashi H Fujimura S | 1999 | Anticancer Res1999,19,: | 3 |
| 3 | Single-port laparoscopic hepatectomy: technique, safety, and feasibility in a clinical case series显示文摘 | Masayasu Aikawa Mitsuo Miyazawa Kojun Okamoto Yasuko Toshimitsu Katsuya Okada Yosuke Ueno Shigeki Yamaguchi Isamu Koyama | 2012 | Surgical Endoscopy2012,,6: | 3 |
| 4 | Rapid acupuncture for musculoskeletal pain in the emergency room of the Hospital Servidor Publico Estadual, Brazil: A quasi-experimental study显示文摘Objective:To compare differences in self-reported musculoskeletal pain before and after receiving rapid acupuncture for pain at an outpatient emergency department.Methods:Exactly 102 patients presenting to the emergency room of the Hospital Servidor Publico Estadual in Sao Paulo,Brazil,participated in this before-and-after study.All participants had musculoskeletal pain and were treated with the technique proposed by Marques Filho.This emergency acupuncture involved inserting a needle at a point defined by traditional Chinese medicine and applying intense stimulation for 10 s;no more than two points were used on any individual patient.Pain was measured using a numerical visual scale before and immediately after the procedure.Results:Participants in this study were mostly women(78%),had a college degree(47%)and were below the age of 60(56%).The most common region of pain was the lower back(31%),and the most common type of pain was acute and exacerbated chronic pain.The meridians most commonly involved were the eight extra meridians(40%),and the points most often used for treatment were Houxi(SI3),Shenmai(BL62)and Zulinqi(GB41).Almost all participants reported a decrease in pain intensity,independent of sex,education level,pain site and pain type(acute/chronic;P<0.05).At the end of the session,only4%of the participants reported a desire for allopathic medication.Conclusion:This emergency acupuncture technique for analgesia appears to reduce musculoskeletal pain.Trial registration:Brazilian Registry of Clinical Trials(http://gffzze635125bcd5b441ahuuxw0w6ckxob66vn.ffgz.tsg.suse.edu.cn/)with No.RBR-8 dmfjf. | Luciana Aikawa Alexandre Massao Yoshizumi Mirian Matsura Shirassu Marcia Kiyomi Koike | 2020 | Journal of Integrative Medicine2020,18,4: | 3 |
| 5 | Polysomnographic assessment of respiratory disturbance during deep propofol sedation for endoscopic submucosal dissection of gastric tumors显示文摘AIM To investigate that polysomnographic monitoring can accurately evaluate respiratory disturbance incidence during sedation for gastrointestinal endoscopy compare to pulse oximetry alone.METHODS This prospective observational study included 10 elderly patients with early gastric cancer undergoing endoscopic submucosal dissection(ESD) under propofol sedation. Apart from routine cardiorespiratory monitoring, polysomnography measurements were acquired. The primary hypothesis was tested by comparing the apnea hypopnea index(AHI), defined as the number of apnea and hypopnea instances per hour during sedation, with and without hypoxemia; hypoxemia was defined as the reduction in oxygen saturation by ≥ 3% from baseline.RESULTS Polysomnography(PSG) detected 207 respiratory disturbances in the 10 patients. PSG yielded a significantly greater AHI(10.44 ± 5.68/h) compared with pulse oximetry(1.54 ± 1.81/h, P < 0.001), thus supporting our hypothesis. Obstructive AHI(9.26 ± 5.44/h) was significantly greater than central AHI(1.19 ± 0.90/h, P < 0.001). Compared with pulse oximetry, PSG detected the 25 instances of respiratory disturbances with hypoxemia 107.4 s earlier on average.CONCLUSION Compared with pulse oximetry, PSG can better detect respiratory irregularities and thus provide superior AHI values, leading to avoidance of fatal respiratory complications during ESD under propofol-induced sedation. | Ryuma Urahama Masaya Uesato Mizuho Aikawa Yukiko Yamaguchi Koichi Hayano Tomoaki Matsumura Makoto Arai Reiko Kunii Shiroh Isono Hisahiro Matsubara | 2018 | World Journal of Gastrointestinal Endoscopy2018,10,11: | 3 |
| 6 | MicroRNA in Cardiovascular Calcification: Focus on Targets and Extracellular Vesicle Delivery Mechanisms显示文摘 | Claudia Goettsch Joshua D. Hutcheson Elena Aikawa | 2013 | Circulation Research2013,,7: | 2 |
| 7 | Overexpression of lymphangiogenic growth factor VEGF-C in human pancreatic cancer显示文摘 | Tang RF Itakura J Aikawa T | | 0,,: | 2 |
| 8 | Overexpression of lymphangiogenic growth factor VEGF-C in human pancreatic cancer显示文摘 | Tang RF Itakura J Aikawa T | 2001 | Pancreas2001,22,3: | 2 |
| 9 | Reactive Oxygen Species, SUMOylation, and Endothelial Inflammation显示文摘 | Nhat-Tu Le James P. Corsetti Janet L. Dehoff-Sparks Charles E. Sparks Keigi Fujiwara Jun-ichi Abe Masanori Aikawa | 2012 | <journal-title>International Journal of Inflammation2012,,: | 2 |
| 10 | Regulation of renal function in thermal injuny显示文摘 | Aikawa N | 1990 | J Trauma1990,30,: | 1 |
| 11 | Targeted deletion of MMP-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction显示文摘 | Ducharme A Frantz S Aikawa M | 2000 | J Clin Invest2000,106,1: | 1 |
| 12 | Transmission-blocking Activity of a Chitinase Inhibitor and Activation of Malarial Parasite Chitinase by Mosquito Protease显示文摘 | Shahabuddin M Toyoshima T Aikawa M | 1993 | Proc Natl Acad Sci USA1993,90,9: | 1 |
| 13 | Neurosecretory granules in small cell invasive carcinoma of the urinary bladder显示文摘 | CRAMER S F AIKAWA M (~I-EILLIN M | 1981 | Cancer1981,47,4: | 1 |
| 14 | Usefulness of procalcitonin serum level for the discrimination of severe sepsis from sepsis: a multicenter prospective study显示文摘 | Shigeatsu Endo Naoki Aikawa Seitaro Fujishima | 2008 | Journal of infec- tion and chemotherapy official journal of the Japan Society of Chemotherapy2008,14,3: | 1 |
| 15 | The heal-ing myocardium sequentially mobilizes two monocytesubsets with divergent and complementary functions显示文摘 | Nahrendorf M Swirski F K Aikawa E | 2007 | J Exp Med2007,204,12: | 1 |
| 16 | Deuterium fractionation in protoplanetary disks显示文摘 | Aikawa Y Herbst E | 1999 | The Astrophysical Journal1999,526,: | 1 |
| 17 | Statins suppress apolipoprotein CIII-induced vascular endothelial cell activation and monocyte adhesion显示文摘 | ZHENG C AZCUTIA V AIKAWA E | 2013 | Eur Heart J2013,34,8: | 1 |
| 18 | Warthin'S tumor of the parotid gland:study of 70 cases显示文摘 | Chedid HM Rapoport A Aikawa KF | 2011 | Rev Col Bras Cir2011,38,2: | 1 |
| 19 | New classification for men with lower urinary tract symptoms:cluster analysis using the Inter- national Prostate Symptom Score 显示文摘 | Aikawa K Yamaguchi O Ogum T | 2012 | BJU Int2012,110,3: | 1 |
| 20 | Osteogenesis associates with inflammation in early-stage atherosclerosis evaluated by molecular imaging in vivo显示文摘 | Aikawa E Nahrendorf M Figueiredo JL | 2007 | Circulation2007,116,24: | 1 |