|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 青藏高原那曲河流域降水及河流水体中氧稳定同位素研究显示文摘根据青藏高原中部那曲河流域 1 998年夏季测得的上下游中稳定同位素的日变化 ,并与同期观测的流域降水中稳定同位素比较 ,分析了河水中δ18O的变化特征 ,初步研究了该流域的稳定同位素水文循环过程。河水中δ18O的变化幅度远小于降水 ,它是降水中δ18O、降水量以及地表蒸发过程共同作用的结果。研究发现湖水对于稳定同位素变化起着显著的调节作用。 | 田立德 姚檀栋 沈永平 杨梅学 叶柏生 Atu.siNUMAGUTI Maki TSUJIMURA | 2002 | 水科学进展2002，13，2： | 43 |
| 2 | Gastric cancer arising from the remnant stomach after distal gastrectomy:A review显示文摘Gastric stump carcinoma was initially reported by Balfore in 1922,and many reports of this disease have since been published. We herein review previous reports of gastric stump carcinoma with respect to epidemiology,carcinogenesis,Helicobacter pylori(H. pylori) infection,Epstein-Barr virus infection,clinicopathologic characteristics and endoscopic treatment. In particular,it is noteworthy that no prognostic differences are observed between gastric stump carcinoma and primary upper third gastric cancer. In addition,endoscopic submucosal dissection has recently been used to treat gastric stump carcinoma in the early stage. In contrast,many issues concerning gastric stump carcinoma remain to be clarified,including molecular biological characteristics and the carcinogenesis of H.pylori infection.We herein review the previous pertinent literature and summarize the characteristics of gastric stump carcinoma reported to date. | Shinsuke Takeno Tatsuya Hashimoto Kenji Maki Ryosuke Shibata Hironari Shiwaku Ippei Yamana Risako Yamashita Yuichi Yamashita | 2014 | World Journal of Gastroenterology2014，20，38： | 13 |
| 3 | 基于隐马尔科夫模型的故障诊断系统研究显示文摘在制造行业中,机械设备的状态检测技术能提供关于设备运行状态的实时信息,为避免生产损失和减少设备的致命故障提供保障。提出了一套基于小波变换和隐马尔科夫模型(HiddenMarkovModels,HMMs)的故障检测系统。提出了小波模极大值分布(WaveletModulusMaximaDistribution),并将之定义为诊断系统的观察量加以验证。同时该系统采用在线模型参数估计和培训算法,通过选取能最大化对数似然度的HMM模型,确定设备所处状态。 | 苗强 Viliam Makis | 2005 | 航空学报2005，26，5： | 13 |
| 4 | Management of a large mucosal defect after duodenal endoscopic resection显示文摘Duodenal endoscopic resection is the most difficult type of endoscopic treatment in the gastrointestinal tract(GI) and is technically challenging because of anatomical specificities. In addition to these technical difficulties, this procedure is associated with a significantly higher rate of complication than endoscopic treatment in other parts of the GI tract. Postoperative delayed perforation and bleeding are hazardous complications, and emergency surgical intervention is sometimes required. Therefore, it is urgently necessary to establish a management protocol for preventing serious complications. For instance, the prophylactic closure of large mucosal defects after endoscopic resection may reduce the risk of hazardous complications. However, the size of mucosal defects after endoscopic submucosal dissection(ESD) is relatively large compared with the size after endoscopic mucosal resection, making it impossible to achieve complete closure using only conventional clips. The over-the-scope clip and polyglycolic acid sheets with fibrin gel make it possible to close large mucosal defects after duodenal ESD. In addition to the combination of laparoscopic surgery and endoscopic resection, endoscopic full-thickness resection holds therapeutic potential for difficult duodenal lesions and may overcome the disadvantages of endoscopic resection in the near future. This review aims to summarize the complications and closure techniques of large mucosal defects and to highlight some directions for management after duodenal endoscopic treatment. | Shintaro Fujihara Hirohito Mori Hideki Kobara Noriko Nishiyama Tae Matsunaga Maki Ayaki Tatsuo Yachida Tsutomu Masaki | 2016 | World Journal of Gastroenterology2016，22，29： | 10 |
| 5 | Structure and function of ALG-2,a penta-EF-hand calcium-dependent adaptor protein显示文摘ALG-2(a gene product of PDCD6) is a 22-kD protein containing five serially repetitive EF-hand structures and belongs to the penta-EF-hand(PEF) family,including the subunits of typical calpains.ALG-2 is the most conserved protein among the PEF family members and its homologs are widely found in eukaryotes.X-ray crystal structures of various PEF proteins including ALG-2 have common features:presence of eightα-helices and dimer formation via paired EF5s that are positioned in anti-parallel orientation.ALG-2 forms a homodimer and a heterodimer with its closest paralog peflin.Like calmodulin,a well-known four-EF-hand protein,ALG-2 interacts with various proteins in a Ca2+-dependent fashion,but the binding motifs are completely different.With some exceptions,ALG-2-interacting proteins commonly contain Pro-rich regions,and ALG-2 recognizes at least two distinct Pro-containing motifs:PPYP(X) nYP(X,variable;n=4 in ALIX and PLSCR3) and PXPGF(represented by Sec31A) .A shorter alternatively spliced isoform,lacking two residues and designated ALG-2 GF122,does not bind ALIX but maintains binding capacity to Sec31A.X-ray crystal structural analyses have revealed that binding of calcium ions induces the configuration of the side chain of R125 so that it opens Pocket 1,which accepts PPYP,but Pocket 1 remains closed in the case of ALG-2 GF122.ALG-2 dimer has two ligand-binding sites,each in a monomer molecule,and appears to function as a Ca2+-dependent adaptor protein to either stabilize a preformed complex or to bridge two proteins on scaffolds in systems of the endosomal sorting complex required for transport(ESCRT) and ER-to-Golgi transport. | Masatoshi MAKI Hironori SUZUKI Hideki SHIBATA | 2011 | Science China(Life Sciences)2011，54，8： | 9 |
| 6 | Reduction effect of bacterial counts by preoperative saline lavage of the stomach in performing laparoscopic and endoscopic cooperative surgery显示文摘AIM:To investigate the effects of gastric lavage with2000 mL of saline in laparoscopic and endoscopic cooperative surgery.METHODS:Twenty two patients who were diagnosed with a gastric gastrointestinal stromal tumor were enrolled.In former term,irrigations of the stomach were conducted whenever it was necessary,not systematically(Non systemic lavage group).In latter term,the stomach was thoroughly cleaned with 2000 mL of saline using an endoscope with a water jet,and Duodenal balloon occlusion was conducted to prevent refluxedbile and pancreatic juice(Systemic lavage+balloon occlusion group).The gastric wall was sprayed with 20mL of distilled water,and 20 mL of gastric juice was collected in a sterile tube and submitted for culture.20mL of ascites was also collected from the laparoscopic ports and submitted for culture.We compared WBC,CRP,BT between two groups,and verify the reduction effect of bacterial counts in Systemic lavage+balloon occlusion group.RESULTS:WBC count before,1 d after,and 3 d after laparoscopic and endoscopic cooperative surgery(LECS)were 5060(95%CI:4250-9640),12140(6050-14110),and 6910(5320-12520)in Non systemic lavage group,4400(3660-7620),8910(6480-10980),and 5950(4840-7860)in Systemic lavage+balloon occlusion group.Significant differences between two groups at the day after LECS(P=0.029)and the 3 d after LECS(P=0.042).CRP levels in Non systemic lavage group and in Systemic lavage+balloon occlusion group were significantly different at the day after LECS(P=0.005)and the 3 d after LECS(P=0.028).BTs(℃)in Non systemic lavage group and in Systemic lavage+balloon occlusion group were also significantly different at the day after LECS(P=0.004)and the 3 d after LECS(P=0.006).In a logarithmic comparison,bacterial load before gastric lavage,after lavage,and ascites culture were 6.08(95%CI:4.04-6.97),0.48(0-0.85),and 0.21(0-0.56).The bacterial counts before and after gastric lavage were significantly suppressed(P=0.007),but no significant difference between gastric juice culture after lavage and ascites(P=0.154).CONCLUSION:Pre-LECS lavage with 2000 mL of saline exhibited a bacteria-reducing effect equivalent to disinfectants and obtained favorable results in terms of clinical symptoms and data. | Hirohito Mori Hideki Kobara Takaaki Tsushimi Shintaro Fujihara Noriko Nishiyama Tae Matsunaga Maki Ayaki Tatsuo Yachida Joji Tani Hisaaki Miyoshi Asahiro Morishita Tsutomu Masaki | 2014 | World Journal of Gastroenterology2014，20，42： | 9 |
| 7 | Application of A* Algorithm for Real-time Path Re-planning of an Unmanned Surface Vehicle Avoiding Underwater Obstacles显示文摘This paper describes path re-planning techniques and underwater obstacle avoidance for unmanned surface vehicle(USV) based on multi-beam forward looking sonar(FLS). Near-optimal paths in static and dynamic environments with underwater obstacles are computed using a numerical solution procedure based on an A* algorithm. The USV is modeled with a circular shape in 2 degrees of freedom(surge and yaw). In this paper, two-dimensional(2-D) underwater obstacle avoidance and the robust real-time path re-planning technique for actual USV using multi-beam FLS are developed. Our real-time path re-planning algorithm has been tested to regenerate the optimal path for several updated frames in the field of view of the sonar with a proper update frequency of the FLS. The performance of the proposed method was verified through simulations, and sea experiments. For simulations, the USV model can avoid both a single stationary obstacle, multiple stationary obstacles and moving obstacles with the near-optimal trajectory that are performed both in the vehicle and the world reference frame. For sea experiments, the proposed method for an underwater obstacle avoidance system is implemented with a USV test platform. The actual USV is automatically controlled and succeeded in its real-time avoidance against the stationary undersea obstacle in the field of view of the FLS together with the Global Positioning System(GPS) of the USV. | Thanapong Phanthong Toshihiro Maki Tamaki Ura Takashi Sakamaki Pattara Aiyarak | 2014 | Journal of Marine Science and Application2014，13，1： | 8 |
| 8 | Peritoneal bleeding due to percutaneous transhepatic gallbladder drainage:An autopsy report显示文摘A 77-year-old man underwent percutaneous transhepatic gallbladder drainage(PTGBD) for acute cholecystitis as a preoperative procedure;however,he suddenly suffered cardiopulmonary arrest 4 h after the PTGBD and died.There were three centesis scars for the PTGBD,and only one pathway from the most dorsal centesis scar reached the gallbladder.Microscopically,the PTGBD pathway crossed and injured the intrahepatic arterial wall,and hepatic parenchymal bleeding extended along the PTGBD pathway to the inferior surface of the liver.Blood flowed to the peritoneal cavity through a small gap between the liver and gallbladder.Consequently,the PTGBD caused lethal bleeding.When the percutaneous transhepatic cholangio drainage/PTGBD pathway runs close to vessels near the liver surface,it might be necessary to deal with the possibility of rapid and lethal peritoneal bleeding. | Yoko Ihama Maki Fukazawa Kenji Ninomiya Takumi Nagai Chiaki Fuke Tetsuji Miyazaki | 2012 | World Journal of Hepatology2012，4，10： | 7 |
| 9 | Two rare gastric hamartomatous inverted polyp cases suggest the pathogenesis of growth显示文摘Gastric hamartomatous inverted polyps(GHIP)are difficult to diagnose accurately because of inversion into the submucosal layer.GHIP are diagnosed using the pathological characteristics of the tumor,including the fibroblast cells,smooth muscle,nerve components,glandular hyperplasia,and cystic gland dilatation.Although Peutz-Jeghers syndrome,juvenile polyposis,and Cowden disease are hereditary,it is rare to encounter 2 cases of monostotic and asymptomatic gastric hamartomas.The pathogeneses of hamartomatous inverted polyps and inverted hyperplastic polyps remain controversial because of the paucity of reported cases.There are 3 hypotheses regarding the pathogenesis of complete gastric inverted polyps.Based on our experience with 2 successive,rare GHIP cases,we affirm the hypothesis that after a hamartomatous change occurs in the submucosal layer,some of these components are exposed to the gastric mucosa and,consequently,form a hypertrophic lesion.In Case 1,our hypothesis explains why a tiny hypertrophic change was first detected on the top of the submucosal tumor using a detailed narrow band imaging-magnified endoscopy.There was no confirmation that the milky white mucous and calcification structures were exuding directly from the biopsy site like Case 1,and in Case 2 the presence of this mucous was indirectly confirmed during an endoscopic submucosal dissection(ESD).Regarding the pathogenesis of GHIP,a submucosal hamartomatous change may occur prior to the growth of hypertrophic portions.An en bloc resection using ESD is recommended for treatment. | Hirohito Mori Hideki Kobara Takaaki Tsushimi Shintaro Fujihara Noriko Nishiyama Tae Matsunaga Maki Ayaki Tatsuo Yachida Tsutomu Masaki | 2014 | World Journal of Gastroenterology2014，20，19： | 7 |
| 10 | Expression of Angiopoietin-1, 2 and 4 and Tie-1 and 2 in gastrointestinal stromal tumor, leiomyoma and schwannoma显示文摘AIM: To investigate the role of angiopoietin (Ang) -1, -2 and -4 and its receptors, Tie-1 and -2, in the growth and differentiation of gastrointestinal stromal tumors (GISTs).METHODS: Thirty GISTs, seventeen leiomyomas and six schwannomas were examined by immunohistochemistry in this study.RESULTS: Ang-1, -2 and -4 proteins were expressed in the cytoplasm of tumor cells, and Tie-1 and -2 were expressed both in the cytoplasm and on the membrane of all tumors. Immunohistochemical staining revealed that 66.7% of GISTs (20 of 30), 76.5% of leiomyomas (13 of 17) and 83.3% of schwannomas (5 of 6) were positive for Ang-1. 83.3% of GISTs (25 of 30), 82.4% of leiomyomas (14 of 17) and 100% of schwannomas (6 of 6) were positive for Ang-2. 36.7% of GISTs (11 of 30), 58.8% of leiomyomas (10 of 17) and 83.3% of schwannomas (5 of 6) were positive for Ang-4. 60.0% of GISTs (18 of 30), 82.4% of leiomyomas and 100% of schwannomas (6 of 6) were positive for Tie-1. 10.0% of GISTs (3 of 30), 94.1% of leiomyomas (16 of 17) and 33.3% of schwannomas (2 of 6) were positive for Tie-2. Tie-2 expression was statistically different between GISTs and leiomyomas (P < 0.001). However, there was no correlation between expression of angiopoietin pathway components and clinical risk categories.CONCLUSION: Our results suggest that the angiopoietin pathway plays an important role in the differentiation of GISTs, leiomyomas and schwannomas. | Toshiyuki Nakayama Maki Inaba Shinji Naito Yumi Mihara Shiro Miura Mitsuru Taba Ayumi Yoshizaki Chun-Yang Wen Ichiro Sekine | 2007 | World Journal of Gastroenterology2007，13，33： | 6 |
| 11 | p53 promotes AKT and SP1-dependent metabolism through the pentose phosphate pathway that inhibits apoptosis in response to Nutlin-3a显示文摘 | Text Lei Duan Ricardo E. Perez Ling Chen Lothar A. Blatter Carl G. Maki | 2018 | Journal of Molecular Cell Biology2018，10，4： | 6 |
| 12 | 气体燃料发动机的高性能气门座圈材料开发显示文摘烧结材料广泛用于气门座圈(VSI)。当用于气体燃料(LPG,CNG)发动机时,由于环境干燥,VSI磨损量增大。介绍了气体燃料发动机用的,两种新开发的高性能VSI材料。为增高耐磨性,这些材料应用的新工艺是,高性能硬质颗粒和固体润滑剂新分布方法。 | Hideaki Kawata Kunio Maki | 2011 | 粉末冶金技术2011，29，1： | 5 |
| 13 | Irritable bowel syndrome: A concise review of current treatment concepts显示文摘Irritable bowel syndrome(IBS) is one of the most common gastrointestinal disorders causing patients to seek medical treatment. It is relatively resource intensive and the source of significant morbidity. Recent insights into the pathophysiology and treatment of IBS has given clinicians more options than ever to contend with this disorder. The purpose of our paper is to review older, 'classic' treatments for IBS as well as newer agents and 'alternative' therapies. We discuss the evidence base of these drugs and provide context to help develop appropriate treatment plans for IBS patients. | Geoffrey C Wall Ginelle A Bryant Michelle M Bottenberg Erik D Maki rew R Miesner | 2014 | World Journal of Gastroenterology2014，20，27： | 5 |
| 14 | Inhibition of rheumatoid arthritis by blocking connective tissue growth factor显示文摘The pathogenesis of rheumatoid arthritis(RA) remains to be completely elucidated so far; however, it is known that proinflammatory cytokines play a pivotal role in the induction of RA. Tumor necrosis factor(TNF-α), in particular, is considered to play a central role in bone destruction by mediating the abnormal activation of osteoclasts or the production of proteolytic enzymes through direct or indirect mechanisms. The use of TNF-α blocking agents has a significant impact on RA therapy. Anti-TNF-α blocking agents such as infliximab are very effective for treatment of RA, especially for the prevention of articular destruction. We have previously shown that several proteins exhibited extensive changes in their expression after amelioration of RA with infliximab treatment. Among the proteins, connective tissue growth factor(CTGF) has a significantrole for the development of RA. Herein, we review the function of CTGF in the pathogenesis of RA and discuss the possibility of a novel treatment for RA. We propose that CTGF is a potentially novel effector molecule in the pathogenesis of RA. Blocking the CTGF pathways by biological agents may have great beneficial effect in patients with RA. | Kazuhisa Nozawa Maki Fujishiro Yoshinari Takasaki Iwao Sekigawa | 2014 | World Journal of Orthopedics2014，5，5： | 4 |
| 15 | 耐热/耐磨烧结合金发展趋势显示文摘粉末冶金的一个特殊优势是合金设计自由度高,因此,烧结合金广泛用于耐热与耐磨零件。主要产品对象是气门导管、阀座圈(VSI)及发动机排气系统的零件。近年来,为回应环境问题,发动机的使用性能在不断提高,这些零件的使用环境随之越益严苛,因此,就日益要求改进材料的耐磨性与其它性能。论述了近年来耐热/耐磨烧结材料的技术发展趋势,特别着重于材料发展趋势。 | Hideaki Kawata Kunio Maki 韩凤麟 | 2011 | 粉末冶金技术2011，29，5： | 4 |
| 16 | New insights into the phylogeny and biogeography of subfamily Orontioideae (Araceae)显示文摘Proto-Araceae,the earliest diverged lineage within the family Araceae,includes two subfamilies,Gymnostachydoideae(one species)and Orontioideae(eight species).Based on an extensive sampling(a total of 198 accessions)of six chloroplast non-coding regions(5799 aligned sites),we assessed phylogenetic relationships among the genera and species within subfamily Orontioideae and estimated the timing of intercontinental disjunct events in the Northern Hemisphere.Overall phylogenetic relationships among the genera were consistent with results from previous studies,but several new important findings were discovered,primarily within Symplocarpus Salisb.ex W.P.C.Barton.First,two major lineages within Symplocarpus were identified:one lineage included S.foetidus(L.)Salisb.ex W.Barton,S.nabekuraensis Otsuka&K.Inoue,and S.renifolius Schott ex Tzvelev(Japan),whereas the other included S.nipponicus Makino,S.egorovi N.S.Pavlova&V.A.Nechaev,and S.renifolius(Korea).Symplocarpus renifolius in Japan was tetraploid and closely related to the tetraploid S.foetidus in eastern North America.Populations of S.renifolius in Korea were confirmed to be diploid(2n=30)and shared the most recent common ancestor with the other diploid species,S.nipponicus.Second,two recently described species,S.nabekuraensis and S.egorovi,were deeply embedded within S.renifolius in Japan and Korea,respectively,and their distinct taxonomic status requires further assessment.Finally,two intercontinental disjunction events in the subfamily,one in Lysichiton Schott between eastern Asia and western North America and the other in Symplocarpus between eastern Asia and eastern North America,were estimated to be between 4.5 and 1.4 million years ago(Pliocene and Pleistocene)and between 1.9 and 0.5 million years ago(Pleistocene),respectively. | Joon Seon Lee Seon Hee Kim Sangryong Lee Masayuki Maki Koichi Otsuka Andrey E.Kozhevnikov Zoya V.Kozhevnikova Jun Wen Seung-Chul Kim | 2019 | Journal of Systematics and Evolution2019，57，6： | 4 |
| 17 | Implications of hepatic dysfunction in Kawasaki disease:Time-related changes in aspartate aminotransferase, alanine aminotransferase,total bilirubin,and C-reactive protein levels显示文摘Importance:The cause of the hepatic dysfunction that commonly accompanies Kawasaki disease(KD)remains unclear.Objective:We tried to clarify the cause of the hepatic dysfunction.Methods:A total of 381 consecutive patients with acute KD,who had undergone inpatient treatment with intravenous immunoglobulin until the 7th day of illness,were divided into a group of 199 patients with an alanine aminotransferase(ALT)level≥40 IU/L on admission(group I),a group of 52 patients with an ALT level≥40 IU/L at some point after admission(group II),and a group of 130 patients with ALT levels consistently<40 IU/L throughout hospitalization(group III).Aspartate aminotransferase(AST),ALT,total bilirubin(T-Bil),and C-reactive protein(CRP)levels were analyzed over time,and time-courses were compared.results:In the initial stage of illness,in group I,AST,ALT,T-Bil peaked on days 1-3,and AST tended to improve significantly on the 4th day(P<0.001).T-Bil improved on day 5(P<0.01),and ALT improved significantly on day 6(P<0.001).CRP increased every day up to day 6(P<0.001).In group II,AST and ALT increased after admission,and thereafter CRP increased,then decreased.The frequency of use of aspirin and aspirin doses did not differ significantly in the three groups.Interpretation:Recovery from liver dysfunction occurred in the initial stage of illness in group I-within the period of CRP exacerbation,which is an indicator of systemic inflammation. | Yasuhiko Tomita Takashi Fukaya Yasuko Yamaura Rie Tsujiguchi Haruko Muratani Maki Shimaya | 2019 | Pediatric Investigation2019，3，1： | 3 |
| 18 | Plastome phylogenomic insights into the Sino-Japanese biogeography of Diabelia(Caprifoliaceae)显示文摘Understanding the causes of the Sino-Japanese disjunctions in plant taxa has been a central question in eastern Asian biogeography,with vicariance or long-distance dispersal often invoked to explain such patterns.Diabelia Landrein(Caprifoliaceae;Linnaeoideae)comprises four shrubby species with a Sino-Japanese disjunct distribution.The species diversification time within Diabelia,covering a long geological history of the formation process of the Sino-Japanese flora,dated back to the middle Oligocene,therefore,Diabelia would be an ideal model to elucidate the biogeographic patterns of Sino-Japanese disjunctions with climate fluctuation.In this study,we analyzed complete plastome sequence data for 28 individuals representing all four species of Diabelia.These 28 plastomes were found to be highly similar in overall size(156243-157578 bp),structure,gene order,and content.Our phylogenomic analysis of the plastomes supported a close relationship between Diabelia ionostachya(Nakai)Landrein&R.L.Barrett var.wenzhouensis(S.L.Zhou ex Landrein)Landrein from eastern China and Diabelia spathulata(Siebold&Zucc.)Landrein var.spathulata from Japan.Diabelia serrata(Siebold&Zucc.)Landrein was identified as sister to a population of Diabelia sanguinea(Makino)Landrein from Tochigi in central Japan and D.spathulata Landrein,from Toyama,central Japan.Most Diabelia lineages were estimated to have differentiated 8-28 Mya.Our results indicate that two independent vicariance events could explain the disjunction between Japan and Korea in the mid to late Miocene,and between Zhejiang and Japan in the early Miocene. | Hong-Xin Wang Michael J.Moore Russell L.Barrett Sven Landrein Shota Sakaguchi Masayuki Maki Jun Wen Hua-Feng Wang | 2020 | Journal of Systematics and Evolution2020，58，6： | 3 |
| 19 | Large balloon dilation for the treatment of recurrent bile duct stones prevents short-term recurrence in patients with previous endoscopic sphincterotomy显示文摘 | Ryo Harada Hiroyuki Maguchi Kuniyuki Takahashi Akio Katanuma Manabu Osanai Kei Yane Syunpei Hashigo Maki Kaneko Ryusuke Katoh Shin Katoh | 2013 | Journal of Hepato-Biliary-Pancreatic Sciences2013，，5： | 3 |
| 20 | Health evaluation method for degrading systems subject to dependent competing risks显示文摘This paper proposes a health evaluation method for degrading systems subject to competing risks of dependent soft and hard failures. To characterize the time-varying degradation rate, the degradation process is determined by a non-stationary Gamma process and the soft failure is encountered when it exceeds a predefined critical level. For the hard failure, a Cox's proportional hazard model is applied to describe the hazard rate of the time to system failure. The dependent relationship is modeled by incorporating the degradation process as a time-varying covariate into the Cox's proportional hazard model. To facilitate the health characteristics evaluation, a discretization technique is applied both to the degradation process and the monitoring time.All health characteristics can be obtained in the explicit form using the transition probability matrix, which is computationally attractive for practical applications. Finally, a numerical analysis is carried out to show the effectiveness and the performance of the proposed health evaluation method. | ZHAO Shuai MAKIS Viliam CHEN Shaowei LI Yong | 2018 | Journal of Systems Engineering and Electronics2018，29，2： | 3 |
您所在的机构暂未开通此部分的功能，请联系管理员