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| 1 | Characterization of functional biliary pain and dyspeptic symptoms in patients with sphincter of Oddi dysfunction:Effect of papillotomy显示文摘AIM: To characterize functional biliary pain and other gastrointestinal (GI) symptoms in postcholecystectomy syndrome (PCS) patients with and without sphincter of Oddi dysfunction (SOD) proved by endoscopic sphincter of Oddi manometry (ESOM), and to assess the post- endoscopic sphincterotomy (EST) outcome. METHODS: We prospectively investigated 85 cholecystectomized patients referred for ERCP because of PCS and suspected SOD. On admission, all patients completed our questionnaire. Physical examination, laboratory tests, abdominal ultrasound, quantitative hepatobiliary scintigraphy (QHBS), and ERCP were performed in all patients. Based on clinical and ERCP findings 15 patients had unexpected bile duct stone disease and 15 patients had SOD biliary typeⅠ. ESOM demonstrated an elevated basal pressure in 25 patients with SOD biliary-type Ⅲ. In the remaining 30 cholecystectomized patients without SOD, the liver function tests, ERCP, QHBS and ESOM were all normal. As a control group, 30 ‘asymptomatic’ cholecystectomized volunteers (attended to our hospital for general cardiovascular screening) completed our questionnaire, which is consisted of 50 separate questions on GI symptoms and abdominal pain characteristics. Severity of the abdominal pain (frequency and intensity) was assessed with a visual analogue scale (VAS). In 40 of 80 patients having definite SOD (i.e. patients with SOD biliary typeⅠand those with elevated SO basal pressure on ESOM), an EST was performed just after ERCP. In these patients repeated questionnaires were filled at each follow-up visit (at 3 and 6 mo) and a second lookQHBS was performed 3 mo after the EST to assess the functional response to EST. RESULTS: The analysis of characteristics of the abdominal pain demonstrated that patients with common bile duct stone and definite SOD had a significantly higher score of symptomatic agreement with previously determined biliary-like pain features than patient groups of PCS without SOD and controls. In contrary, no significant differences were found when the pain severity scores were compared in different groups of PCS patients. In patients with definite SOD, EST induced a significant acceleration of the transpapillary bile flow; and based on the comparison of VASs obtained from the pre- and post-EST questionnaires, the severity scores of abdominal pain were significantly improved, however, only 15 of 35 (43%) patients became completely pain free. Post-EST severity of abdominal pain by VASs was significantly higher in patients with predominant dyspepsia at initial presentation as compared to those without dyspeptic symptoms. CONCLUSION: Persistent GI symptoms and general patient dissatisfaction is a rather common finding after EST in patients with SOD, and correlated with the presence of predominant dyspeptic symptoms at the initial presentation, but does not depend on the technical and functional success of EST. | László Madácsy Roland Fejes Gábor Kurucsai Ildikó Joó András Székely Viktória Bertalan Attila Szepes János Lonovics | 2006 | World Journal of Gastroenterology2006，12，42： | 33 |
| 2 | 美国临床生化科学院检验医学实践指南:睾丸、前列腺、结直肠、乳腺及卵巢癌肿瘤标志物的应用显示文摘经美国临床生化科学院(NCAB)授权,由鄢盛恺教授组织学者、专家翻译审定2009年NCAB检验医学实践指南:睾丸、前列腺、结直肠、乳腺及卵巢癌中肿瘤标志物的应用单行本(Catharine M.Sturgeon教授和Eleftherios P.Diaman-dis教授编辑)。该指南包含第1至6章共6部分内容,参加指南制订的专家阵容强大,分别从临床及检验角度对睾丸、前列腺、结直肠、乳腺及卵巢癌中肿瘤标志物的检测与临床应用方面的问题进行了详细阐述与说明,是目前国内外在肿瘤实验诊断方面的纲领性应用文件。不仅适合广大检验人员、临床医护人员学习使用,也非常适合相关仪器试剂生产厂商研发应用。本指南由刘洋、薛丽、林文涛、李江、梁红艳、顾兵、潘世扬、郑磊等翻译,姜晓峰、沈文梅、田亚平、鄢盛恺审校,最后由鄢盛恺统稿审定。本指南的翻译出版,不仅有助于我国检验人员和医护人员合理的检测和应用睾丸、前列腺、结直肠、乳腺及卵巢癌肿瘤标志物,对我国检验医学指南的编写与应用也有一定的借鉴作用。本刊特在本期刊发,以飨广大读者。 | 鄢盛恺 Ulf-Hkan Stenman Rolf Lamerz Leendert H.Looijenga Nils Brünner Michael J.Duffy Caj Haglund Mads Holten-Andersen Hans JФrgen Nielsen Francisco J.Esteva Nadia Harbeck Daniel F.Hayes Rafael Molina Daniel W.Chan Robert C.Bast Jr Ie-Ming Shih Lori J.Sokoll Gyrgy Slétormos 刘洋 梁红艳 姜晓峰 田亚平 薛丽 林文涛 顾兵 潘世扬 沈文梅 郑磊 李江 | 2012 | 临床检验杂志2012，30，2： | 32 |
| 3 | Endoscopic transluminal pancreatic necrosectomy using a self-expanding metal stent and high-flow water-jet system显示文摘Walled-off pancreatic necrosis and a pancreatic abscess are the most severe complications of acute pancreatitis. Surgery in such critically ill patients is often associated with significant morbidity and mortality within the first few weeks after the onset of symptoms. Minimal invasive approaches with high success and low mortality rates are therefore of considerable interest. Endoscopic therapy has the potential to offer safe and effective alternative treatment. We report here on 3 consecutive patients with infected walled-off pancreatic necrosis and 1 patient with a pancreatic abscess who underwent direct endoscopic necrosectomy 19-21 d after the onset of acute pancreatitis. The infected pancreatic necrosis or abscess was punctured transluminally with a cystostome and, after balloon dilatation, a non-covered self-expanding biliary metal stent was placed into the necrotic cavity. Following stent deployment, a nasobiliary pigtail catheter was placed into the cavity to ensure continuous irrigation. After 5-7 d, the metal stent was removed endoscopically and the necrotic cavity was entered with a therapeutic gastroscope. Endoscopic debridement was performed via the simultaneous application of a high-flow water-jet system; using a flush knife, a Dormia basket, and hot biopsy forceps. The transluminal endotherapy was repeated 2-5 times daily during the next 10 d. Supportive care included parenteral antibiotics and jejunal feeding. All patients improved dramatically and with resolution of their septic conditions; 3 patients were completely cured without any further complications or the need for surgery. One patient died from a complication of prolonged ventilation severe bilateral pneumonia, not related to the endoscopic procedure. No procedure related complications were observed. Transluminal endoscopic necrosectomy with temporary application of a self-expanding metal stent and a high-flow water-jet system shows promise for enhancing the potential of this endoscopic approach in patients with walled-off pancreatic necrosis and/or a pancreatic abscess. | István Hritz Roland Fejes András Székely Iván Székely László Horváth gnes Sárkány ron Altorjay László Madácsy | 2013 | World Journal of Gastroenterology2013，19，23： | 10 |
| 4 | MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors显示文摘 | Liu Xi Sempere Lorenzo F Ouyang Haoxu Memoli Vincent A Andrew Angeline S Luo Yue Demidenko Eugene Korc Murray Shi Wei Preis Meir Dragnev Konstantin H Li Hua DiRenzo James Bak Mads Freemantle Sarah J Kauppinen Sakari Dmitrovsky Ethan | 2010 | Journal of Clinical Investigation2010，，4： | 3 |
| 5 | A centralized energy-efficient routing protocol for wireless sensor networks 显示文摘 | MURUGANATHAN S D MAD C F BHASIN R I | 2005 | IEEE Radio Communication2005，43，3： | 1 |
| 6 | Perinatal systemic in-flammatory response syndrome and retinopathy of prematurity 显示文摘 | SOOD B G MAD AN A SAHA S | 2010 | Pediatr Res2010，67，4： | 1 |
| 7 | A eentrialized energy-efficient routing protocol for wireless sensor networks 显示文摘 | MURUGANATHAN S D MAD C F BHASIN R I | 2005 | IEEE Radio Communications2005，43，3： | 1 |
| 8 | Being human:Language:a social history of words显示文摘 | SZATHMRY E SZMAD S | 2008 | Nature2008，456，： | 1 |
| 9 | Small-diameter silicon nanowire surfaces 显示文摘 | MAD D D LEE C S AU F C K | 2003 | Science2003，299，： | 1 |
| 10 | Spectral definition of the Macro - algae Ulva curvata in the Back - barrier Bays of the eastern shore of Virginia,USA显示文摘 | Elijah R Amina R Mads S T | 2012 | Int J Remote Sens2012，33，2： | 1 |
| 11 | Effect of treatment tem- perature on the early hydration characteristics of su- perplasticized silica fume blended cement pastes 显示文摘 | Heikal M Morsy M S Mad I | 2005 | Cement and Concrete Research2005，35，4： | 1 |
| 12 | Optimization of strength and ductility of 2024A1 by equal channel angular pressing (ECAP) and post-ECAP aging 显示文摘 | KIM W J CHUNG C S MAD S HONG S I KIM H K | 2003 | Scripta Mater2003，49，4： | 1 |
| 13 | HAZOP analysis management system with dynamic visual model aid显示文摘 | Mad Sahar N B Ardi S Kazuhiko S | 2010 | American Journal of Applied Sciences2010，，7： | 1 |
| 14 | Effect of du- ration of passive stretch on hip abduction range of motion显示文摘 | MADDING S W WONG J G HALLUM A | 1987 | J Orthop Sport Phys1987，8，40： | 1 |
| 15 | Arsenic Pollution in Groundwater from Hetao Area, China 显示文摘 | ZHANG H MAD S HU X X | 2002 | Environ- mental Geology2002，41，6： | 1 |
| 16 | Grey Theory and Practical Application 显示文摘 | Liu S F mad Lin Y | 2006 | Springer-Verlag2006，2，： | 1 |
| 17 | Optimization of strength and ductility of 2024 A1 by equal channel angular pressing (ECAP) and post-ECAP aging显示文摘 | KIM W J CHUNG C S MAD S | 2003 | Scripta Mate- rialia2003，49，4： | 1 |
| 18 | Cognitive impairment in chronic heroin addicts显示文摘 | A mad S Ahmad H Bindra G | 1989 | J Pers Clin Stud1989，5，： | 1 |
| 19 | A centralized energy-efficient routing protocol for wireless sensor networks显示文摘 | MURUGANATHAN S D MAD C F BHASIN R I | 2005 | IEEE Communications Magazine2005，43，3： | 1 |
| 20 | Microsurgical removal of a petrous apex meningioma after stereotactic radiation; technical case report显示文摘 | MADⅡD SAMⅡ STEFFEN K ROSAHL S K MARCOS S TATAGIBA | 2001 | Neurosurgery2001，49，1： | 1 |
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