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    题名 作者 年代 出处 被引量
12019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W 2020中华高血压杂志2020,28,3:516
2Reconstruction of chemically burned rat corneal surface by bone marrow-derived human mesenchymal stem cells显示文摘Ma Y Xu Y Xiao Z Yang W Zhang C Song E Du Y Li L 2006中国生物学文摘2006,20,5:58
3Cell-to-cell contact induces mesenchymal stem cell to differentiate into cardiomyocyte and smooth muscle cell显示文摘Wang T Xu Z Jiang W Ma A 2006中国生物学文摘2006,20,5:48
4新型冠状病毒公认受体血管紧张素转换酶2的单细胞RNA表达情况显示文摘研究发现,2019新型冠状病毒与严重急性呼吸综合征-冠状病毒(severe acute respiratory syndromecoronavirus,SARS-CoV)存在相同的受体———血管紧张素转换酶2(angiotensin converting enzyme 2,ACE2)。在此,研究者基于公共数据库和最新的单细胞转录组测序技术,分析了ACE2RNA在正常人肺中的表达谱。结果表明,ACE2的表达集中在一小部分Ⅱ型肺泡上皮细胞中。刘青(译) 叶鹏(审校) Zhao Y Zhao Z Wang Y Zhou Y Ma Y Zuo W 2020中华高血压杂志2020,28,3:24
5Proteomic analysis of human ovaries from normal and polycystic ovarian syndrome显示文摘Ma,X Fan,L Meng,Y Hou,Z Mao,YDL Wang,W Ding,W Liu,JY 2007南京医科大学学报(自然科学版)2007,27,11:20
6胸背根神经节或肋间神经脉冲射频调制治疗老年带状疱疹后神经痛的疗效和安全性回顾性研究显示文摘带状疱疹后神经痛(PHN)是由水痘带状疱疹病毒感染引起的一种慢性疼痛,常见于老年人。PHN的典型临床症状是持续的刺痛或灼痛,伴自发性疼痛,严重影响老年患者的生活质量。其发病机制复杂,治疗困难。脉冲射频(PRF)是一种对靶神经施加脉冲电流的微创技术。最近的研究证实了PRF对术后疼痛、周围神经病理性疼痛和带状疱疹后神经痛的有益作用。胸神经(T1~12)是PHN最常见的受累部位,发病率高达50%。研究表明,背根神经节(DRG)和肋间神经(ICN)联合PRF治疗胸椎带状疱疹后遗神经痛均有效。Huang X Ma Y Wang W 潘雪芹(编译) 2021中华医学杂志2021,101,43:15
7Dietary factors and smoking as risk factors for PD in a rural population in China: a nested case-control study显示文摘Ma L Zhang L Gao XH Chen W Wu YP Wang Y Li XF Como P Kieburtz K Qiao YL 2006中国生物学文摘2006,20,8:13
8胡萝卜软腐果胶杆菌巴西亚种(Pectobacterium carotovorum subsp.brasiliense)引起的黄瓜细菌性软腐病在中国发生显示文摘2014—2015年,在中国山东、山西、河北、河南、辽宁等省的黄瓜茎叶上发生了毁灭性的细菌性软腐病,造成了黄瓜产业严重的经济损失。黄瓜叶片、茎、叶柄和果实表面出现流胶;茎基部呈深褐色进而出现湿腐。受侵染的黄瓜叶边缘出现黄斑和湿腐症状,并逐渐扩散至叶片中心。从受侵染组织中分离出45个细菌菌株,在形态学特性鉴定、生理学、生物化学和16Sr RNA基因序列分析的基础上,将病原体鉴定为胡萝卜软腐果胶杆菌(Pectobacterium carotovorum)。多位点序列分析(MLSA)证实,分离菌株是胡萝卜软腐果胶杆菌巴西亚种[Pectobacterium carotovorum subsp.brasiliensis(Pcb)],病原菌归入进化枝II。重新分离获得与原始菌株相同的菌株,证实了分离菌株的致病力。寄主范围测试表明,该菌株具有广泛的寄主范围。目前为止,这是对Pcb引起的黄瓜软腐病——这一对黄瓜生产具有重要经济影响的病害在中国乃至全球范围内的首次报道。冯志琴(译) meng x l chai a l shi y x xie x w ma z h li b j 2017中国植保导刊2017,37,7:10
9Epidemiological serosurvey of Hepatitis B in China—Declining HBV prevalence due to Hepatitis B vaccination显示文摘Xiaofeng Liang Shengli Bi Weizhong Yang Longde Wang Gang Cui Fuqiang Cui Yong Zhang Jianhua Liu Xiaohong Gong Yuansheng Chen Fuzhen Wang Hui Zheng Feng Wang Jing Guo Zhiyuan Jia Jingchen Ma Huaqing Wang Huiming Luo Li Li Shuigao Jin Stephen C. Hadler Yu W 2009Vaccine2009,,47:7
10儿童期肥胖、成年期肥胖和心血管风险因子显示文摘过去30年,儿童超重或肥胖的发生率明显增加[1]。儿童期肥胖是死亡率增加的预测因子,这主要是由于儿童期肥胖可导致心血管疾病发生率增加。相关的预测研究提示"肥胖流行症"可能改变目前心血管疾病死亡率下降的趋势,使现今儿童的寿命缩短。Juonala M Magnussen CG Berenson GS Venn A Burns TL Sabin MA Srinivasan SR Daniels SR Davis PH Chen W Sun C Cheung M Viikari JS Dwyer T Raitakari OT 叶鹏 2012中华高血压杂志2012,20,1:6
11改良DBL法测定稻米中的赖氨酸含量显示文摘王红梅 刘巧泉 Joyce W C Ma Samuel S M Sun 2002扬州大学学报(农业与生命科学版)2002,23,4:5
12Sol-gel derived HA/TiO_2 double coatings on Ti scaffolds for orthopaedic applications显示文摘Hydroxyapatite/titania (HA/TiO2) double layers were coated onto Ti scaffolds throughout for orthopaedic applications by sol-gel method. Differential scanning calorimetry (DSC), thermogravimetric analysis (TG) and X-ray diffractometry (XRD) were used for the characterisation of the phase transformations of the dried gels and coated surface structures. Scanning electron microscope (SEM) equipped with energy dispersive spectrometry (EDS) was used for the observation and evaluation of the morphology and phases of the surface layers and for the assessment of the in vitro tests. The in vitro assessments were performed by soaking the HA/TiO2 double coated samples into the simulated body fluid (SBF) for various periods. The TiO2 dipping-coating method at a speed of 12 cm/min, followed by a heat treatment at 600 ℃ for 20 min. The HA la lyaeyre wr wasa ssu cbosaetqeude bnytl ya dipping-coated on the outer surface at the same speed and then heat-treated at difference temperatures. The results indicat that the HA phase begins to crystallize after a heat treatment at 560 ℃. The crystallinity increases obviously at 760 ℃. SEM observations find no delamination or crack at the interfaces of HA/TiO2 and TiO2/Ti. The HA/TiO2 coated Ti scaffolds displays excellent bone-like apatite forming ability when it is soaked into SBF. Ti scaffolds after HA/TiO2 double coatings can be anticipated as promising implant materials for orthopaedicXU W HU W Y LI M H MA Q Q P. D. HODGSON WEN C E 2006中国有色金属学会会刊:英文版2006,16,B01:5
13Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial显示文摘Wendy S Atkin Rob Edwards Ines Kralj-Hans Kate Wooldrage Andrew R Hart John MA Northover D Max Parkin Jane Wardle Stephen W Duffy Jack Cuzick 2010The Lancet2010,,9726:4
14Comparison of HER-2/neu,ER and PCNA expression in premenopausal and postmenopausal patients with breast carcinoma显示文摘Zheng W Zheng J Ma L Meng F Huang L Ma D 2005第二军医大学学报2005,26,8:4
15Nat Genet:单基因突变导致过敏性皮炎的发生显示文摘最近,研究者们鉴定出了一类导致神经性皮炎发生的关键基因突变:CARDll。来自美国NIH过敏与传染病研究所的研究者们通过对四个没有血缘关系的患病家庭进行分析,发现了这一导致疾病产生的基因、Chi A Ma, Yuan Zhang, Michael A Weinreich, Jonathan J Lyons, Celeste G Nelson, Thomas DiMaggio, Kelly D Stone, Joshua D Milner Jeffrey R Stinson, Elisa Ruffo, Batsukh Dorjbal, Swadhinya Arjunaraja, Kelsey Voss, Andrew L Snow Jordan K Abbott, Pia J Hauk, Paul R Reynolds, Erwin W Gelfand Elisa Ruffo Salomé Glauzy, Natsuko Yamakawa, Eric Meffre Jennifer Stoddard, Julie Niemela, Sergio D Rosenzweig Yu Zhang, Helen F Matthews Joshua J McElwee Nina Jones Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, Silvia Danielian, Jonathan Zaiat, Marcelo A Marti Brian Kim Megan A Cooper Neil Romberg 2017现代生物医学进展2017,17,27:3
16Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial显示文摘Wendy S Atkin Rob Edwards Ines Kralj-Hans Kate Wooldrage Andrew R Hart John MA Northover D Max Parkin Jane Wardle Stephen W Duffy Jack Cuzick 20102010 (9726)2010,,9726:3
17The mitochondrial genome encodes abundant small noncoding RNAs显示文摘识别的小 noncoding RNA 都被原子染色体远因此编码。这里,我们主要报导鼠科、人的 mitochondrial 染色体编码几千小 noncoding RNA,它是源于 mitochondrial 基因(主人基因) 的感觉抄本,并且我们称为这些小 RNA mitochondrial 编码染色体的小 RNA (mitosRNAs ) 。影响的 DICER inactivation,但是完全没废除 mitosRNA 生产。MitosRNAs 看起来是当前未辩别出的 mitochondrial ribonucleases 的产品。提高的表示在 vitro 他们的主人基因铺平的 mitosRNAs 的 Overexpression,和 dysregulated mitosRNA 表示通常在 vivo 与异常 mitochondrial 基因表示被联系。我们的数据证明除了 37 已知的 mitochondrial 基因,哺乳动物的 mitochondrial 染色体也编码丰富的 mitosRNAs,它可以在房间在 mitochondrial 基因表示的控制起一个重要规章的作用。Seungil Ro Hsiu-Yen Ma Chanjae Park Nicole Ortogero Rui Song Grant W Hennig Huili Zheng Yung-Ming Lin2 Loredana Moro Jer-Tsong Hsieh wei Yant 2013Cell Research2013,23,6:3
18Exploiting novel molecular targets in gastrointestinal cancers显示文摘Novel molecular targets are being discovered as we learn more about the aberrant processes underlying various cancers. Efforts to translate this knowledge are starting to impact on the care of patients with gastrointestinal cancers. The epidermal growth factor receptor (EGFR) pathway and angiogenesis have been targeted successfully in colorectal cancer with cetuximab, panitunumab and bevacizumab. Similarly, EGFR-targeting with erlotinib yielded significant survival benefit in pancreatic cancer when combined with gemcitabine. The multi-targeting approach with sorafenib has made it the first agent to achieve significant survival benefit in hepatocellular carcinoma. Efforts to exploit the dysregulated Akt/mTOR pathway in GI cancer therapy are ongoing. These molecular targets can be disrupted by various approaches, including the use of monoclonal antibody to intercept extracellular ligands and disrupt receptor-ligand binding, and small molecule inhibitors that interrupt the activation of intracellular kinases.Wen W Ma Manuel Hidalgo 2007World Journal of Gastroenterology2007,13,44:3
19Variations in Wool Growth with Nutrient Supply in Northern China显示文摘Field studies on essessment of nutritional status of the grazing sheep were carried out in each of the three major grassland regions, the eastern Inner Mongolia and beyond grassland, the Inner Mongolia - Ningxia - Gansu grassland and the Xinjiang grassland, in northern China. The results obtained showed that the wool production of fine wool sheep in these regions varied between regions and seasons, with similar seasonal patterns in all regions and that reducing the seasonal variations in nutrient supply would enhance wool production substantially. Nutritional limitations to wool growth of the grazing sheep in these regions were suggested, those were: the shortage of protein supply in winter and early spring; the poor quality of much of the pasture and the hay used as supplements, the low energy intake during winter which probably necessitated the use of body stores to maintain body temperature.D X Lu,Iner(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)Z C Feng,(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)H R Wang,(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)R Z Yang,(Xinjiang Institute of Animal Science.Xinjiang Academy of Animal Science.Yiu Hou Road.Urumqi.Xinjiang Uygur Autonomous Region PRC)C T Ma,(Chinese Academy of Agricultural Sciences.Lanzhou.Gansu.PRC)D B Purser,(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014)J R Lindsay(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014)D W Peter(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014) 1997畜牧与饲料科学1997,22,S1:3
2017beta-estradiol attenuates alpha, beta-meATP-induced currents in rat dorsal root ganglion neurons显示文摘Ma B Rong W Dunn PM Burnstock G 2005第二军医大学学报2005,26,10:2
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