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| 1 | Management of proximal humerus fractures in adults显示文摘The majority of proximal humerus fractures are lowenergy osteoporotic injuries in the elderly and their incidence is increasing in the light of an ageing population. The diversity of fracture patterns encountered renders objective classification of prognostic value challenging. Non-operative management has been associated with good functional outcomes in stable, minimally displaced and certain types of displaced fractures.Absolute indications for surgery are infrequent and comprise compound, pathological, multi-fragmentary head-splitting fractures and fracture dislocations, as well as those associated with neurovascular injury. A constantly expanding range of reconstructive and replacement options however has been extending the indications for surgical management of complex proximal humerus fractures. As a result, management decisions are becoming increasingly complicated, in an attempt to provide the best possible treatment for each indi-vidual patient, that will successfully address their specific fracture configuration, comorbidities and functional expectations. Our aim was to review the management options available for the full range of proximal humerus fractures in adults, along with their specific advantages, disadvantages and outcomes. | Leonidas Vachtsevanos Lydia Hayden Aravind S Desai Asterios Dramis | 2014 | World Journal of Orthopedics2014，5，5： | 22 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | SIRT3 Is a mitochondrial tumor suppressor:a scientific tale that connects aberrant cellular ROS,the warburg effect, and carcinogenesis 显示文摘 | Marcia C H Deng C X Lydia W S | 2012 | Cancer Research2012，72，10： | 1 |
| 4 | Young age is an independent prognostic factor for survival of sporadic renal cell carcinoma显示文摘 | Ricardo F S Charles J R Lydia T M | 2004 | J Urol2004，171，61： | 1 |
| 5 | Expression of COX-2 on Reed-Sternberg cells is an independent unfavorable prognostic factor in Hodgkin lymphoma treated with ABVD显示文摘 | Francisco Mestre Antonio Gutierrez Rafael Ramos Jordi Martinez-Serra Lydia Sánchez Gabriel Matheu Teresa Ros Juan Fernando Garcia Jose Rodriguez | 2012 | Blood2012，，25： | 1 |
| 6 | Proper folding of the antifungal protein PAF is required for optimal activ-ity显示文摘 | Florentine M Willibald S Lydia K | 2005 | Research in Microbiology2005，156，： | 1 |
| 7 | Advanced algorithms for wind turbine power curve modeling显示文摘 | Lydia M Immanuel Selvakumar A Suresh Kumar S | 2013 | IEEE Transactions on Sustainable Energy2013，4，3： | 1 |
| 8 | Selenium determination in urine with atomic fluorescence detection显示文摘 | ROSA S ROSER R LYDIA G-B | 2001 | Analytica Chimica Acta2001，436，2： | 1 |
| 9 | Growth of very low birth weight infant to age 20 year显示文摘 | Maureen H Mark S Lydia C | 2003 | J Pediatr2003，112，： | 1 |
| 10 | Sexual Behaviors and Risks Among Bisexually-and Gay-Identified Young Latino Men 显示文摘 | Gail A Lydia OD Ann S | | AIDS and Behavior0，8，2： | 1 |
| 11 | Time-effect of monte-lukast on protection against exercise-induced bronchocon-striction显示文摘 | Diego GP Lydia P Marco S | 2011 | Respir Med2011，105，12： | 1 |
| 12 | A Distinctive, Delayed Form of Exertional Rhabdomyolysis显示文摘 | Lydia S Ronald H | 2014 | Neurology2014，82，4： | 1 |
| 13 | Can Bispectral Index Monitoring Predict Recovery of Consciousness in Patients with Severe Brain Injury?显示文摘 | Neus Fàbregas Pedro L. Gambús Ricard Valero Enrique J. Carrero Lydia Salvador Elysabeth Zavala Enrique Ferrer | 2004 | Anesthesiology2004，，1： | 1 |
| 14 | Growth of very low birth weight infant to age 20 year 显示文摘 | Maureen H Mark S Lydia C | 2003 | J Pediatr2003，112，： | 1 |
| 15 | Development of tubular and glomerular ceils of the kidney 显示文摘 | Lydia S Ekblom P | 1992 | Kidney Int1992，41，8： | 1 |
| 16 | Circadian gene expression patterns of melanopsin and pinopsin in the chick pineal gland显示文摘 | HEIKE H LYDIA E RAINER S | 2005 | Biochem Biophys Res Commun2005，326，： | 1 |
| 17 | Glypican-3 regulates migration, adhesion and actin cytoskeleton organization in mammary tumor cells through Wnt signaling modulation 显示文摘 | Ivan S Lydia P Jorge F | 2009 | Breast cancer research and treatment2009，114，2： | 1 |
| 18 | Nutritional model of steatohepatitis and metabolic syndrome in the ossabaw miniature swine显示文摘 | Lydia L Mouhamad A Romil S | 2009 | Hepatology2009，50，1： | 1 |
| 19 | MRP3, BCRP, and P-Glycoprotein activities are prognostic factors in adult acute myeloid leukemia显示文摘 | ZINEB B ANNE MF LYDIA S | 2005 | Clin Cancer Res2005，11，21： | 1 |
| 20 | Probabilistic roadmaps for path planning in high- dimensional configuration spaces显示文摘 | Lydia E K Petr S | 1996 | IEEE Transactions on Robotics And Automation1996，12，4： | 1 |
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