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| 1 | Effects of heat shock on change of HSC70/HSP68,acid and alkaline phosphatases before and after rat partial hepatectomy显示文摘INTRODUCTIONOnly the liver has the great capability ofregeneration in mammal.Few hepatocytes are inthe phase of division in the normal liver of an adultmammal (including human beings),but theremaining hepatocytes can be induced to proliferatequickly by partial hepatectomy (PH),and,to somedegree,they stop dividing and re-differentiate intocells functioning as hepatocytes.This shows | Lu AL Xu CS | 2000 | World Journal of Gastroenterology2000，6，5： | 27 |
| 2 | Structuring Nonlinear Wavefront Emitted from Monolayer Transition-Metal Dichalcogenides显示文摘The growing demand for tailored nonlinearity calls for a structure with unusual phase discontinuity that allows the realization of nonlinear optical chirality,holographic imaging,and nonlinear wavefront control.Transition-metal dichalcogenide(TMDC)monolayers offer giant optical nonlinearity within a few-angstrom thickness,but limitations in optical absorption and domain size impose restriction on wavefront control of nonlinear emissions using classical light sources.In contrast,noble metal-based plasmonic nanosieves support giant field enhancements and precise nonlinear phase control,with hundred-nanometer pixellevel resolution;however,they suffer from intrinsically weak nonlinear susceptibility.Here,we report a multifunctional nonlinear interface by integrating TMDC monolayers with plasmonic nanosieves,yielding drastically different nonlinear functionalities that cannot be accessed by either constituent.Such a hybrid nonlinear interface allows second-harmonic(SH)orbital angular momentum(OAM)generation,beam steering,versatile polarization control,and holograms,with an effective SH nonlinearityχ^((2))of~25 nm/V.This designer platform synergizes the TMDC monolayer and plasmonic nanosieves to empower tunable geometric phases and large field enhancement,paving the way toward multifunctional and ultracompact nonlinear optical devices. | Xuanmiao Hong Guangwei Hu Wenchao Zhao Kai Wang Shang Sun Rui Zhu Jing Wu Weiwei Liu Kian Ping Loh Andrew Thye Shen Wee Bing Wang Andrea Alù Cheng-Wei Qiu Peixiang Lu | 2020 | Research2020，，1： | 5 |
| 3 | Cardiac differentiation and electrophysiology characteristics of bone marrow mesenchymal stem cells显示文摘 | LIU Bo-wu LU An-lin HOU Jing HUANG Wei LI Yao HOU Zhao-lei HOU Hong DA Jing YANG Na Al Shi-yi | 2012 | Chinese Medical Journal2012，，18： | 3 |
| 4 | TBK1-medicated DRP1 phosphorylation orchestrates mitochondrial dynamics and autophagy activation in osteoarthritis显示文摘Mitochondrial dynamics,including mitochondrial fission and fusion,are critical for maintaining mitochondrial functions.Evidence shows that TANK-binding kinase 1(TBK1)regulates mitochondrial fusion and fission and then mitophagy.Since a previous study demonstrates a strong correlation between mitophagy and osteoarthritis(OA),we herein investigated the potential role of TBK1 in OA process and mitochondrial functions.We demonstrated a strong correlation between TBK1 and OA,evidenced by significantly downregulated expression of TBK1 in cartilage tissue samples of OA patients and in the chondrocytes of aged mice,as well as TNF-α-stimulated phosphorylation of TBK1 in primary mouse chondrocytes.TBK1 overexpression significantly attenuated TNF-α-induced apoptosis and abnormal mitochondrial function in primary mouse chondrocytes.Furthermore,TBK1 overexpression induced remodeling of mitochondrial morphology by directly phosphorylating dynamin-related protein 1(DRP1)at Ser637,abolishing the fission of DRP1 and preventing its fragmentation function.Moreover,TBK1 recruitment and DRP1 phosphorylation at Ser637 was necessary for engulfing damaged mitochondria by autophagosomal membranes during mitophagy.Moreover,we demonstrated that APMK/ULK1 signaling contributed to TBK1 activation.In OA mouse models established by surgical destabilization of the medial meniscus,intraarticular injection of lentivirus-TBK1 significantly ameliorated cartilage degradation via regulation of autophagy and alleviation of cell apoptosis.In conclusion,our results suggest that the TBK1/DRP1 pathway is involved in OA and pharmacological targeting of the TBK1-DRP1 cascade provides prospective therapeutic benefits for the treatment of OA. | Sun-li Hu Abdullah Al Mamun Jian Shaw Sun-long Li Yi-feng Shi Xue-man Jin Ying-xin Yu Chao-zhi Pang Ze-yang Li Jia-jie Lu Yue-piao Cai Xiang-yang Wang Jian Xiao | 2023 | Acta Pharmacologica Sinica2023，44，3： | 2 |
| 5 | Effect of gTaphene oxide nanosheets of microstructure and mechanical properties of cement composites 显示文摘 | LU S H MAY J QIU C C el al | 2013 | Construction and Building Materials2013，49，： | 1 |
| 6 | Diagnostic accuracy of varying discrminatory zones for the prediction of ectopic pregnancy in women with a pregnancy of unknown location 显示文摘 | Condous G Kirk E Lu C at al | 2005 | Ultrasound Obstet Gynecol2005，26，7： | 1 |
| 7 | Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D显示文摘 | Castellino RC De Bortoli M Lu X et al | 2008 | J Neurooncol2008，86，3： | 1 |
| 8 | Covalent bonded polymer-gra-phene nanocomposites显示文摘 | Fang M Wang K G Lu H B el al | 2010 | Journal of Polymer Science Part A:Poly-mer Chemistry2010，48，19： | 1 |
| 9 | Demethylation of CD40LG on the inactive X in T cells from women with lupus显示文摘 | Lu QJ Wu AL Tesmer L etal | 2007 | J Im- munol2007，179，9： | 1 |
| 10 | TNF, acting through inducibly expressed TNFR2, drives activation and cell cycle entry of c‐Kit<sup>+</sup> cardiac stem cells in ischemic heart disease显示文摘 | Rafia S. Al‐Lamki Wanhua Lu Jun Wang Jun Yang Timothy J. Sargeant Richard Wells Chenqu Suo Penny Wright Martin Goddard Qunhua Huang Amir H. Lebastchi George Tellides Yingqun Huang Wang Min Jordan S. Pober John R. Bradley | 2013 | Stem Cells2013，，9： | 1 |
| 11 | Partial ieast-squares-dis-criminant analysis differentiating Chinese wolfberriesby UPLC-MS and flow injection mass spectrometric(FIMS) fingerprints 显示文摘 | Lu W Jiang Q Shi H ei al | 2014 | Journal of Agricultural andFood Chemistry2014，62，37： | 1 |
| 12 | Elevated levels of urinary 8 - hydroxy - 2 - deoxygnanosine, lymphocytic micronucei, and ser- um glutathione S - transferase in workers exposed to coke oven e- missions显示文摘 | Liu AL Lu WQ Wang ZZ | 2006 | Environ Health Perspect2006，114，5： | 1 |
| 13 | Facile preparation of graphene nanoribbon filled silicone rubber nanocomposiie with improved thermal and mechanical properties显示文摘 | Gan Lu Shang Songmin Yuen Chunwah Marcus eL al | 2015 | Composites:Part B2015，，69： | 1 |
| 14 | Justifying video-assisted thoracic surgery for spontaneous hemopneumothorax 显示文摘 | Wu YC Lu MS Yeh CH et al | 2002 | Chest2002，122，5： | 1 |
| 15 | Agricultural soil monitoring ofPCDD/Fs in the vicinity of a municipal solid waste incinerator inEastern China : Temporal variations and possible sources 显示文摘 | Xu M X Yan J H Lu Y S ef al | 2009 | Journal of Hazardous Materials2009，166，23： | 1 |
| 16 | Intluence of the oxida- tive annealing temperature on tile magnetism of (Mn, N )- codoped ZnO thin films 显示文摘 | LU Z L YAN G Q WANG S el al | 2008 | Journal of Applied Physics2008，104，1： | 1 |
| 17 | MicroRNA expression profilesclassify human oancers显示文摘 | Lu J Getz G Miska EA el al | 2005 | Nature2005，435，7043： | 1 |
| 18 | In vitro induced CD4(q-)CD25(q-) Foxp3 (q-) Tregs attenuate hepatic ischemia-reperfusion injury 显示文摘 | Lu L Li G RAO J e al | 2009 | Int Immunopharmacol2009，9，11： | 1 |
| 19 | A multiobjective modeling approach to locating incinerators显示文摘 | Luís Al?ada-Almeida Jo?o Coutinho-Rodrigues John Current | 2008 | Socio-Economic Planning Sciences2008，，2： | 1 |
| 20 | Silk matrix for tissue engineered anterior cruciate ligaments 显示文摘 | ALTMAN G H HORAN R L LU H H ct al | 2002 | Biomaterials2002，23，20： | 1 |
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