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| 1 | Hospitalized prevalence and 5-year mortality for IBD:Record linkage study显示文摘AIM:To establish the hospitalized prevalence of severe Crohn's disease(CD) and ulcerative colitis(UC) in Wales from 1999 to 2007;and to investigate long-term mortality after hospitalization and associations with social deprivation and other socio-demographic factors.METHODS:Record linkage of administrative inpatient and mortality data for 1467 and 1482 people hospitalised as emergencies for ≥ 3d for CD and UC,respectively.The main outcome measures were hospitalized prevalence,mortality rates and standardized mortality ratios for up to 5 years follow-up after hospitalization.RESULTS:Hospitalized prevalence was 50.1 per 100 000 population for CD and 50.6 for UC.The hospitalized prevalence of CD was significantly higher(P < 0.05) in females(57.4) than in males(42.2),and was highest in people aged 16-29 years,but the prevalence of UC was similar in males(51.0) and females(50.1),and increased continuously with age.The hospital-ized prevalence of CD was slightly higher in the most deprived areas,but there was no association between social deprivation and hospitalized prevalence of UC.Mortality was 6.8% and 14.6% after 1 and 5 years follow-up for CD,and 9.2% and 20.8% after 1 and 5 years for UC.For both CD and UC,there was little discernible association between mortality and social deprivation,distance from hospital,urban/rural residence and geography.CONCLUSION:CD and UC have distinct demographic profiles.The higher prevalence of hospitalized CD in more deprived areas may reflect higher prevalence and higher hospital dependency. | Lori A Button Stephen E Roberts Michael J Goldacre Ashley Akbari Sarah E Rodgers John G Williams | 2010 | World Journal of Gastroenterology2010，16，4： | 3 |
| 2 | Outcome of cytomegalovirus infections in patients with inflammatory bowel disease显示文摘 | Konstantinos A Papadakis Jim K Tung Scott W Binder Lori Y Kam Maria T Abreu Stephan R Targan Eric A Vasiliauskas | 2001 | The American Journal of Gastroenterology2001，，7： | 2 |
| 3 | Induction of a high incidence of lung tumors in C57BL/6 mice with multiple ethyl carbamate injections显示文摘 | York E Miller Lori D Dwyer-Nield Robert L Keith Mysan Le Wilbur A Franklin Alvin M Malkinson | 2003 | Cancer Letters2003，，2： | 2 |
| 4 | What is the ideal approach for emergent pericardiocentesis using point-of-care ultrasound guidance?显示文摘BACKGROUND:Traditionally performed using a subxiphoid approach,the increasing use of point-of-care ultrasound in the emergency department has made other approaches(parasternal and apical)for pericardiocentesis viable.The aim of this study is to identify the ideal approach for emergency-physician-performed ultrasound-guided pericardiocentesis as determined by ultrasound image quality,distance from surface to pericardial fl uid,and likely obstructions or complications.METHODS:A retrospective review of point-of-care cardiac ultrasound examinations was performed in two urban academic emergency departments for the presence of pericardial eff usions.The images were reviewed for technical quality,distance of eff usion from skin surface,and predicted complications.RESULTS:A total of 166 pericardial effusions were identified during the study period.The mean skin-to-pericardial fl uid distance was 5.6 cm(95%confi dence interval[95%CI]5.2-6.0 cm)for the subxiphoid views,which was signifi cantly greater than that for the parasternal(2.7 cm[95%CI 2.5-2.8 cm],P<0.001)and apical(2.5 cm[95%CI 2.3-2.7 cm],P<0.001)views.The subxiphoid view had the highest predicted complication rate at 79.7%(95%CI 71.5%-86.4%),which was signifi cantly greater than the apical(31.9%;95%CI 21.4%-44.0%,P<0.001)and parasternal(20.2%;95%CI 12.8%-29.5%,P<0.001)views.CONCLUSIONS:Our results suggest that complication rates with pericardiocentesis will be lower via the parasternal or apical approach compared to the subxiphoid approach.The distance from skin to fl uid collection is the least in both of these views. | Lori Stolz Elaine Situ-LaCasse Josie Acuña Matthew Thompson Nicolaus Hawbaker Josephine Valenzuela Uwe Stolz Srikar Adhikari | 2021 | World Journal of Emergency Medicine2021，12，3： | 2 |
| 5 | 【特刊综述】雄激素和前列腺疾病显示文摘越来越多的文献认同睾酮治疗在性腺机能低下患者中具有促合成代谢作用。而关于老年男性使用外源性雄激素的风险和其对前列腺潜在副作用的研究数据仍然匮乏。老年和性腺机能低下男性接受睾酮治疗是否会加重下尿路症状或加剧、揭露,甚至刺激前列腺癌发展,这一问题使采用睾酮治疗的热情有所减缓,与此同时前列腺疾病被视作睾酮治疗的相对禁忌。雄激素对于前列腺的发育和维护是必要的。无论如何,流行病学研究并没有一致地发现内源性血清雄激素浓度与前列腺疾病风险之间存在正相关。虽然最新研究显示5α还原酶抑制剂降低了患低级别前列腺癌的风险,说明抑制雄激素代谢有利于前列腺健康,但是对于高级别前列腺癌并没有类似作用,因此对这些药物化学预防的真正临床效益提出了质疑。鉴于缺乏大样本随机试验,很难了解如何最好地研究雄激素和前列腺疾病发展之间的关系。越来越多研究质疑雄激素在血清中的变化与其在前列腺激素环境中的变化有类似效应或者改变腺体内雄激素的调节过程。需要长期的干预性研究来真正证实雄激素对前列腺组织和疾病风险的操控。然而,现有数据认为恢复血清雄激素至生理水平并不会触发前列腺疾病。 | Lori A Cooper Stephanie T Page | 2014 | Asian Journal of Andrology2014，16，2： | 2 |
| 6 | Hydroxyurea in the treatment of HIV infection: clinical efficacy and safety concerns显示文摘 | Lisziewicz J Foli A Lori WM | 2003 | Drug Saf2003，26，9： | 1 |
| 7 | Induction of HIV-specific memory T-cell responses by topical DermaVir vaccine显示文摘 | CALAROTA S A WEINER D B LORI F | 2007 | Vaccine2007，25，16： | 1 |
| 8 | Exploring internet addiction:demographic characteristics and stereotypes of heavy internet users显示文摘 | Lori C Soul L Wayne Shell Betty A Kleen | 2003 | The Journal of Computer Information System2003，，3： | 1 |
| 9 | Modelling in data base management systems显示文摘 | GRAY J N LORIE R A PUTZOLU G R | 1976 | Chapter Granularity of locks and degrees of consistency in a shared data base1976，，： | 1 |
| 10 | The State of the States: Quality Counts显示文摘 | MEYER LORI ORLOFSKY GREG F SKINNER RONALD A SP1CER SCOTT | 2002 | Education Week2002，21，17： | 1 |
| 11 | Dimethyl carbonate as an am- bident electrophile 显示文摘 | Tundo P Rossi L Loris A | 2002 | Acc Chem Res2002，35，： | 1 |
| 12 | Ractopamine increases total and myofibrillar protein synthesis in cultured rat myotubes metabolism and hormonal regulation显示文摘 | William G H Lorie C P | 1990 | Journal of Nutrition1990，120，： | 1 |
| 13 | Faculty mentors' and students' perceptions of students' research selfefficacy显示文摘 | Elise L.Lev a John Kolassa b Lori L.Bakken c | | 0，，30： | 1 |
| 14 | Exploiting Database Parallelism in A Message- passing Multiprocessor 显示文摘 | Lorie R A Daudenarde J Stamos J W | 1991 | IBM Journal of Research and Development1991，35，56： | 1 |
| 15 | Cognitive and psychosocial features in childhood and juvenile MS: Twu-year follow-up显示文摘 | Amato MP Goretti B Ghezzi A Lori S Zipoli V Moiola L | 2010 | Neurology2010，75，13： | 1 |
| 16 | Calibrating corn color from aerial photographs to predict sidedress nitrogen need 显示文摘 | Scharf P C Lory J A | 2002 | Agronomy Journal2002，94，： | 1 |
| 17 | Calibrating corn color from aerial photegraphs to predict side dress N need显示文摘 | Lory J A | 2002 | Agronomy Journal2002，94，： | 1 |
| 18 | Lipoprotein-associated phospholipase A2 is an independent predictor of incident coronary heart disease in an apparently healthy older population: the Rancho Bernardo Study显示文摘 | Lori B Daniel S Gail A | 2008 | J Am Coll Cardiol2008，51，9： | 1 |
| 19 | Intrauterine growth retardation leads to the development of type 2 diabetes inthe rat显示文摘 | Rebecca A Simmons Lori J | 2001 | Diabetes2001，50，： | 1 |
| 20 | Dimethyl carbonate as an ambident electrophile显示文摘 | Rossi L Loris A | 2005 | J Org Chem2005，70，6： | 1 |
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