|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Diagnostic strategy for occult hepatitis B virus infection显示文摘In 2008,the European Association for the study of the liver(EASL) defined occult hepatitis B virus infection (OBI) as the'presence of hepatitis B virus(HBV) DNA in the liver(with detectable or undetectable HBV DNA in the serum) of individuals testing hepatitis B surface antigen(HBsAg) negative by currently available assays'.Several aspects of occult HBV infection are still poorly understood,including the definition itself and a standardized approach for laboratory-based detection,which is the purpose of this review.The clinical significance of OBI has not yet been established;however,in terms of public health,the clinical importance arises from the risk of HBV transmission.Consequently,it is important to detect high-risk groups for occult HBV infection to prevent transmission.The main issue is,perhaps,to identify the target population for screening OBI.Viremia is very low or undetectable in occult HBV infection,even when the most sensitive methods are used,and the detection of the viral DNA reservoir in hepatocytes would provide the best evaluation of occult HBV prevalence in a defined set of patients.However,this diagnostic approach is obviously unsuitable:blood detection of occult hepatitis B requires assays of the highest sensitivity and specificity with a lower limit of detection<10 IU/mL for HBV DNA and<0.1 ng/mL for HBsAg. | Sara Ocana Maria Luisa Casas Ingrid Buhigas Jose Luis Lledo | 2011 | World Journal of Gastroenterology2011，17，12： | 16 |
| 2 | Early Prediction of Anastomotic Leak in Colorectal Cancer Surgery by Intramucosal pH显示文摘 | Monica Millan M.D. Ph.D. Eduardo García-Granero M.D. Ph.D. Blas Flor M.D. Ph.D. Stephanie García-Botello M.D. Salvador Lledo M.D. Ph.D | 2006 | Diseases of the Colon & Rectum2006，，5： | 2 |
| 3 | Adult neurogenesis andfunctional plasticity in neuronal circuits 显示文摘 | Lledo PM Alonso M Grubb MS | 2006 | Nat Rev Neurosci2006，7，3： | 1 |
| 4 | The role of cytokinins and ethylene inhibitors on lenticel hypertrophy generation and ethylene production in vitro cultures of Populus euphratica Oliver显示文摘 | Lledo M D Crespo M B Amomasco J B | 1995 | Israel of Plant Science1995，43，： | 1 |
| 5 | No effect of the CYP1A2* 1F genotype on thioridazine, mesoridazine, sullo ridazine plasma concentrations in psychiatric patients显示文摘 | Dorado P Berecz R Penas LLedo EM | 2007 | Eur J Clin Pharmacol2007，63，5： | 1 |
| 6 | Amenities and rural Appalachian gowth显示文摘 | Deller C Lledo V | 2007 | Agricultural and Resource Econom/cs Review2007，36，1： | 1 |
| 7 | The learning curve in ambulatory laparoseopic cholecystectomy显示文摘 | Serra AS Roig MP Lledo J B | 2002 | Surg Laparose Endose Percutan Tech2002，12，5： | 1 |
| 8 | Preoperative treatment combining capecitabine with radiation therapy in rectal cancer:a GERCOR Phase Ⅱ Study显示文摘 | Dupuis O Vie B Lledo G | 2007 | Ontology2007，73，34： | 1 |
| 9 | PSA-NCAM:an important regu-lator of hippocampal plasticity显示文摘 | Cremer H Chazal G Lledo PM | 2000 | Int J Dev Neurosc12000，18，23： | 1 |
| 10 | Adult neurogenesis and functional plasticity in neuronal circuits 显示文摘 | Lledo PM Aloaso M Grubb MS | 2006 | Nature Reviews Neuroscience2006，7，3： | 1 |
| 11 | Preoper- ative treatment combining capecitabine with radiation therapy in rectal cancer:a GERCOR Phase II Study显示文摘 | Dupuis O Vie B Lledo G :t al | 2007 | Oncdogy2007，73，34： | 1 |
| 12 | The impact of adult neurogenesis on olfactory bulb circuits and computations显示文摘 | Lepousez G Valley MT Lledo PM | 2013 | Annu Rev Physiol2013，75，1： | 1 |
| 13 | Hantavirus infections in Spain: analysis of sera from the general population and from patients with pneumonia, renal disease and hepatitis显示文摘 | Lledo L Klingstrom J Gegundez MI | 2003 | J Clin Virol2003，27，： | 1 |
| 14 | Finalresuhs of OPTIMOX2, a large randomized phase ]I study of maintenance therapy or chemotherapy-free intervals (CFI) after FOLFOX in patients with metastatic colorectal cancer (MRC): A GERCOR study 显示文摘 | Maindrault-Goebel F Lledo G Chibaudel B | 2007 | J Clin Oncol2007，25，18： | 1 |
| 15 | Cetuximab Shows Activity in Colorectal Cancer Patients With Tumors for Which FISH Analysis Does Not Detect an Increase in EGFR Gene Copy Number显示文摘 | Antoine Italiano MD Philippe Follana MD Fran?ois-Xavier Caroli MD Jean-Luc Badetti MD Daniel Benchimol MD Georges Garnier MD Jean Gugenheim MD Juliette Haudebourg MD Frédérique Keslair MS Gérard Lesbats MD Gérard Lledo MD Jean-Francois Roussel MD Florence | 2008 | Annals of Surgical Oncology2008，，2： | 1 |
| 16 | Chronic inhibition of nitric oxide synthesis enhances both subventricular zone neurogenesis and olfactory learning in adult mice显示文摘 | Romero - Grimaldi C Gheusi G Lledo PM | 2006 | Eur J Neurosci2006，24，9： | 1 |
| 17 | Amenities and rural Appalachian growth 显示文摘 | Deller C Lledo V | 2007 | Agricultural and Resource Economics Review2007，36，1： | 1 |
| 18 | Can chemotherapy be discontinued in unresectable metastatic colorectal cancer? The GERCOR OPTIMOX2 Study 显示文摘 | Chibaudel B Maindrauh-Goebel F Lledo G | 2009 | J Clin Oncol2009，27，34： | 1 |
| 19 | Can chemotherapy be discontinued in unresectable Metastatic colorectal cancer? The GERCOR OPTIMOX2 study显示文摘 | Chibaudel B Maindrault-Goebel F Lledo G | | 0，，34： | 1 |
| 20 | Any Clinical Benefit From the Use of Oncofoetal Markers in the Management of Chemotherapy for Patients with Metastatic Colorectal Carcinomas?显示文摘 | V. Trillet-Lenoir F. Chapuis S. Touzet J.Y. Barbier G. Freyer J.L. Gaudin C. Lombard-Bohas P.J. Valette G. Lledo M.C. Gouttebel J.D. Boyer L. Chassignol H. Hamon S. Claudel-Bonvoisin E. Leprince P. Amoyal O. Glehen P. Darnand M.O. Heilmann J.P. Bleuse | 2004 | Clinical Oncology2004，，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员