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| 1 | Circulating tumor DNA 5-hydroxymethylcytosine as a novel diagnostic biomarker for esophageal cancer显示文摘 | Xin Tian Baofa Sun Chuanyuan Chen Chunchun Gao Ji Zhang XingYu Lu Linchen Wang Xiangnan Li Yurong Xing Ruijuan Liu Xiao Han Zheng Qi Xiaojian Zhang Chuan He Dali Han Yun-Gui Yang Quancheng Kan | 2018 | Cell Research2018，28，5： | 12 |
| 2 | Responses of activities, abundances and community structures of soil denitrifiers to short-term mercury stress显示文摘The responses of activities, abundances and community structures of soil denitrifiers to mercury (Hg) stress were investigated through a short-term incubation experiment. Four soil treatments with different concentrations of Hg (CK, Hg25, Hg50, and Hg100, denoted as 0, 25, 50, and 100 mg Hg/kg dry soil, respectively) were incubated for 28 days. Soil denitrification enzyme activity (DEA) was measured at day 3, 7 and 28. The abundances and community structures of two denitrification concerning genes, nirS (cd1-nitrite reductase gene) and nosZ (nitrous oxide reductase gene), were analyzed using real-time PCR and denaturing gradient gel electrophoresis (DGGE). Results showed that soil DEA was significantly stimulated in the treatments of Hg25 and Hg50 compared with others at day 7. Meanwhile, no difference in the abundances of soil nirS and nosZ was found between Hg spiked treatments and CK, except the lower abundance of nirS (P < 0.05) in the Hg added treatments compared with that in the CK at day 28. The community structures of denitrifiers based on nirS gene presented obvious change at day 7 along with the Hg additions, however, no variation was found in all treatments based on the nosZ gene. The results indicated that Hg (Hg25 and Hg50) had a strongly short-term stimulation on soil DEA, and nirS gene is more sensitive than nosZ gene to Hg stress. | Zhifeng Zhou Yuanming Zheng Jupei Shen Limei Zhang Yurong Liu Jizheng He | 2012 | Journal of Environmental Sciences2012，24，3： | 8 |
| 3 | FHY3 and FAR1 Integrate Light Signals with the miR156-SPL Module-Mediated Aging Pathway to Regulate Arabidopsis Flowering显示文摘In response to competition for light from their neighbors,shade-intolerant plants flower precociously to ensure reproductive success and survival.However,the molecular mechanisms underlying this key developmental switch are not well understood.Here,we show that a pair of Arabidopsis transcription factors essential for phytochrome A signaling,FAR-RED ELONGATED HYPOCOTYL3(FHY3)and FAR-RED IMPAIRED RESPONSE1(FAR1),regulate flowering time by integrating environmental light signals with the miR156-SPL module-mediated aging pathway.We found that FHY3 and FAR1 directly interact with three flowering-promoting SQUAMOSA-PROMOTER BINDING PROTEIN-LIKE(SPL)transcription factors,SPL3,SPL4,and SPL5,and inhibit their binding to the promoters of several key flowering regulatory genes,including FRUITFUL(FUL),LEAFY(LFY),APETALA1(AP1),and MIR172C,thus downregulating their transcript levels and delaying flowering.Under simulated shade conditions,levels of SPL3/4/5 proteins increase,whereas levels of FHY3 and FAR1 proteins decline,thus releasing SPL3/4/5 from FHY3/FAR1 inhibition to allow activation of FUL,LFY,AP1,and MIR172C and,consequently,early flowering.Taken together,these results unravel a novel mechanism whereby plants regulate flowering time by integrating environmental cues(such as light conditions)and an internal developmental program(the miR156-SPL module-mediated aging pathway). | Yurong Xie Qin Zhou Yongping Zhao Quanquan Li Yang Liu Mengdi Ma Baobao Wang Rongxin Shen Zhigang Zheng Haiyang Wang | 2020 | Molecular Plant2020，13，3： | 8 |
| 4 | 5-Hydroxymethylome in Circulating Cell-free DNA as A Potential Biomarker for Non-small-cell Lung Cancer显示文摘Non-small-cell lung cancer(NSCLC), the most common type of lung cancer accounting for 85% of the cases, is often diagnosed at advanced stages owing to the lack of efficient early diagnostic tools. 5-Hydroxymethylcytosine(5 hmC) signatures in circulating cell-free DNA(cfDNA) that carries the cancer-specific epigenetic patterns may represent the valuable biomarkers for discriminating tumor and healthy individuals, and thus could be potentially useful for NSCLC diagnosis. Here,we employed a sensitive and reliable method to map genome-wide 5 hmC in the cfDNA of Chinese NSCLC patients and detected a significant 5 hmC gain in both the gene bodies and promoter regions in the blood samples from tumor patients compared with healthy controls. Specifically, we identified six potential biomarkers from 66 patients and 67 healthy controls(mean decrease accuracy>3.2, P < 3.68E-19) using machine-learning-based tumor classifiers with high accuracy. Thus,the unique signature of 5 hmC in tumor patient's cfDNA identified in our study may provide valuable information in facilitating the development of new diagnostic and therapeutic modalities for NSCLC. | Ji Zhang Xiao Han Chunchun Gao Yurong Xing Zheng Qi Ruijuan Liu Yueqin Wang Xiaojian Zhang Yun-Gui Yang Xiangnan Li Baofa Sun Xin Tian | 2018 | Genomics, Proteomics & Bioinformatics2018，16，3： | 7 |
| 5 | Direct synthesis of L10-FePt nanopartides from single-source bimetallic complex and their electrocatalytic applications in oxygen reduction and hydrogen evolution reactions显示文摘L10-FePt nan oparticles(NPs)with high chemical ordering represent effective electrocatalysts to reduce the cost and enhance theircatalytic performanee in fuel cells.A molecular strategy of preparing highly ordered FePt NPs was used by direct pyrolysis of a Fe,Pt-containing bimetallic complex.The resultant L10-FePt NPs had very high crystallinity as reflected by the obvious diffractionpatterns,clear lattice fringes and characteristic X-ray diffraction peaks,etc.Besides,the strong ferromagnetism with room temperaturecoercivity of 27 kOe further confirmed the face-centered tetrag on al(fet)phase in good agreement with the ordered nano structures.TheFePt NPs can be used as electrocatalysts to catalyze oxygen reduction reaction(ORR)in an O2·saturated 0.1 M HClO4 solution andhydrogen evolution reaction(HER)in the 0.5 M H2SO4 electrolyte with much better performance than commercial Pt/C,and showedquite high stability after 10,000 cycles.The strategy utilizing orga no metallic precursors to prepare metal alloy NPs was dem on strated tobe a reliable approach for improving the catalytic efficiency in fuel cells. | Zhengong Meng Fei Xiao Zhuoxun Wei Xuyun Guo Ye Zhu Yurong Liu Guijun Li Zhen-Qiang Yu Minhua Shao Wai-Yeung Wong | 2019 | Nano Research2019，12，12： | 5 |
| 6 | Consensus control of stochastic multi-agent systems: a survey显示文摘In this article, we provide a review of the consensus control problem for stochastic multi-agent systems(MASs). Recent advances are surveyed according to the method of occurrence of the stochasticity of the MASs. First, the consensus problem is discussed for MASs, wherein individual agents are corrupted by random noises, i.e., the dynamics of agents involve stochasticity in process and/or measurement equations. Both additive noises and multiplicative noises are surveyed in detail and special attention is paid to the MASs whose dynamics are governed by It?o differential equations. Moreover, particular effort is devoted to presenting the latest progress on the consensus problem for a special type of stochastic MAS with Markovian jump parameters. Subsequently,the relevant research is summarized for MASs with noisy communication environments and stochastic sampling.Further, we provide a systematic review of the consensus problems for MASs whose communication topology varies randomly in the process of data propagation among agents. Finally, conclusions are drawn and several potential future research directions are outlined. | Lifeng MA Zidong WANG Qing-Long HAN Yurong LIU | 2017 | Science China(Information Sciences)2017，60，12： | 5 |
| 7 | Study on Forced Convective Heat Transfer of Non-Newtonian Nanofluids显示文摘This paper is concerned with the forced convective heat transfer of dilute liquid suspensions of nanoparticles(nanofluids) flowing through a straight pipe under laminar conditions. Stable nanofluids are formulated by usingthe high shear mixing and ultrasonication methods. They are then characterised for their size, surface charge,thermal and theological properties and tested for their convective heat transfer behaviour. Mathematical modellingis performed to simulate the convective heat transfer of nanofluids using a single phase flow model and consideringnanofluids as both Newtonian and non-Newtonian fluid. Both experiments and mathematical modellingshow that nanofluids can substantially enhance the convective heat transfer. Analyses of the results suggest thatthe non-Newtonian character of nanofluids influences the overall enhancement, especially for nanofluids with anobvious non-Newtonian character. | Yurong He Yubin Men Xing Liu Huilin Lu Haisheng Chen Yulong Ding | 2009 | Journal of Thermal Science2009，18，1： | 4 |
| 8 | Solar heating assisted rapid cleanup of viscous crude oil spills using reduced graphene oxide-coated sponges显示文摘The rapid cleanup of heavy crude oil spills is challenging due to the poor mobility of highly viscous oil.Traditional absorption strategies involve heating oils to a relatively high temperature to reduce their viscosity,but this method is expensive.Herein,a solar-heated reduced graphene oxide(rGO)-wrapped melamine sponge(MS)was proposed to rapidly absorb oil.The prepared rGO-MS exhibited good hydrophobicity and oleophilicity and could be used for the rapid cleanup of oil spills from water.In addition,the excellent photothermal conversion effect of rGO enabled the rGO-MS composite to achieve a solar energy absorption efficiency of 91%.Due to the localized solar energy collection and wetting properties of rGO-MS,viscous oil near the contact region was effectively heated,enabling rapid heavy oil recovery under solar light illumination.This proposed solar heating-assisted viscous oil sorbent has great promise for use in heavy oil spill cleanups in the future. | WANG XinZhi LIU Dan CHENG Gong HUANG YuDong HE YuRong | 2020 | Science China(Technological Sciences)2020，63，8： | 4 |
| 9 | Integrin β4 was downregulated on the airway epithelia of asthma patients显示文摘流上皮的功能的动态平衡的上皮的房间和损失是的航线气喘的主要病理学的特征;然而,位于这些病理下面的机制仍然保持阴暗。我们的以前的工作证明在 integrin 的 5 flanking 区域有三个变化地点 4 在气喘病人,它与 integrin 的减少的表示被相关 4 在外部白血球。Integrin 4 是航线 epithelia 上的一个重要结构的粘附分子保留上皮的房间的结构的粘附。在这个工作,我们进一步表明了 4 表示是的那 integrin 在气喘病人的航线 epithelia 的 downregulated。探查在 integrin 的 imbalanced 表示之间的关系 4 并且航线的机能障碍在气喘的上皮的房间, integrin 4 由 integrin 是在人的支气管的上皮房间(16HBE14O ) 的 silenced 4 小介入的 RNA lentivirus 向量。在 integrin 的 silencing 之上 4, 16HBE14O 房间显示出减少的增长和创伤修理。大多数房间被显示在 integrin 以后在 G1 阶段被逮捕 4 silencing,和增加的 apoptosis 在 integrin 4 沉默房间被导致。在摘要,我们的结果提供了引人注目的证据那 integrin 4 涉及结构的正直和航线的功能的动态平衡上皮的房间。它是可能的 4 在气喘航线 epithelia 上贡献的 integrin 的那 downregulation 航线的结构的混乱和机能障碍上皮的房间。 | Chi Liu Yang Xiang Huijun Liu Yun Li Yurong Tan Xiaolin Zhu DanZeng Menglan Li Liwen Zhang Xiaoqun Qin | 2010 | Acta Biochimica et Biophysica Sinica2010，42，8： | 4 |
| 10 | Fabrication and characterization of novel meso-porous carbon/n-octadecane as form-stable phase change materials for enhancement of phase-change behavior显示文摘In this study, series of novel composite phase change materials(PCMs) were prepared through vacuum impregnation by using meso-porous carbon as a supporting matrix and n-octadcane as PCMs.The meso-porous carbon material was prepared through one-pot co-assembly method, using resorcinol and formaldehyde as carbon precursor, tetraethoxysilane as silica sources and triblock copolymer F127 as a template. And the phase behaviors of n-octadcane confined in the nano-porous structure of the meso-porous carbon were further investigated. Fourier transform-infrared spectroscopy spectra show that n-octadecane was effectively encapsulated in the porous structure of mesoporous carbon and the composite PCMs were successfully prepared. Differential scanning calorimetry results confirm that the composite PCMs possess a good phase change behavior, fast thermal-response rate and excellent thermal cycling stability. In addition, the composite PCMs possess expected heat storage and heat release properties. All these results demonstrate that the composite PCMs possess good comprehensive property so that they can be used widely in energy storage systems. | Yurong Liu Yongpeng Xia Kang An Chaowei Huang Weiwei Cui Sheng Wei Rong Ji Fen Xu Huanzhi Zhang Lixian Sun | 2019 | Journal of Materials Science & Technology2019，35，5： | 4 |
| 11 | Physicochemical and tribological properties of gemini-type halogen-free dicationic ionic liquids显示文摘A series of new halogen-free dicationic ionic liquids(ILs)with different alkyl chain lengths were prepared,and the relationship between the alkyl chain length,physicochemical and tribological properties of ILs,and their role as neat lubricant for steel–steel friction pairs,was investigated.Evaluation of stability during hydrolysis and copper strip corrosion test results show that synthetic ILs are stable and not corrosive to metal contacts,due to the halogen-free anions.The friction and wear test results indicate that ILs with long alkyl chains have excellent friction-reducing and anti-wear properties,especially at high temperatures.Based on the surface three-dimensional(3D)profiles,electrical contact resistance,scanning electron microscopy(SEM),energy dispersive X-ray spectroscopy(EDS),and the X-ray photoelectron spectrometry(XPS)analysis of the worn surfaces of steel discs,we can conclude that the efficiency of ILs is due to the formation of high quality tribofilms that consist of both tribochemical reaction and ordered absorption films. | Qiangliang YU Chaoyang ZHANG Rui DONG Yijun SHI Yurong WANG Yanyan BAI Jiaying ZHANG Meirong CAI Feng ZHOU Weimin LIU | 2021 | Friction2021，9，2： | 3 |
| 12 | Ir nanoclusters confined within hollow MIL-101(Fe)for selective hydrogenation ofα,β-unsaturated aldehyde显示文摘Although the selective hydrogenation ofα,β-unsaturated aldehyde to unsaturated alcohol(UOL)is an extremely important transformation,it is still a great challenge to achieve high selectivity to UOL due to thermodynamic favoring of the C=C hydrogenation over the C=O hydrogenation.Herein,we report that iridium nanoclusters(Ir NCs)confined within hollow MIL-101(Fe)expresses satisfied reaction activity(93.9%)and high selectivity(96.2%)for the hydrogenation of cinnamaldehyde(CAL)to cinnamyl alcohol(COL)under 1 bar H;atmosphere and room temperature.The unique hollow structure of MIL-101(Fe)benefits for the fast transport of reactant,ensuring the comparable reaction activity and better recyclability of Ir@MIL-101(Fe)than the counterparts which Ir NCs were on the surface of MIL-101(Fe).Furthermore,The X-ray photoelectron spectroscopy data indicates the electropositive Ir NCs,owing to the electron transfer from Ir to MIL-101(Fe),can interact with oxygen lone pairs,and Fourier transform infrared spectrum shows the Lewis acid sites in MIL-101(Fe)can strongly interact with C=O bond,which contributes to a high selectivity for COL.This work suggests the considerable potential of synergetic effect between hollow MOFs and metal nanoclusters for selective hydrogenation reactions. | Qinglin Liu Qian Liu Yurong Chen Yinle Li Hui Su Qinghua Liu Guangqin Li | 2022 | Chinese Chemical Letters2022，33，1： | 3 |
| 13 | Mechanical properties and finite element analysis of walnut under different cracking parts显示文摘In order to reduce mechanical damage and improve extraction quality of walnut kernel during walnut cracking,the Wen-185 walnut cultivar was selected as the research object,and the mechanical properties of walnut under different cracking parts were assessed by combining compression tests and finite element analysis(FEA)method.The compression test results showed that the relationships between rupture force and deformation of walnut were nonlinear,and the cracking process of shell mainly consisted of three stages(elastic stage,plastic stage and composite elastic-plastic stage).The best method to crack walnut was the spherical compression,and the peak value of rupture force and corresponding deformation were 211.83 N and 1.68 mm,respectively.In condition of spherical compression,the shell-breaking rate,first-grade kernel rate and whole kernel rate were(91.67±2.89)%,(88.33±2.89)%,(80.00±5.00)%,respectively.The FEA results indicated that spherical compression was also the suitable way to rupture walnut,which resulted in the obvious propagation trends of shell cracks and further a better integrity of extracting walnut kernel.Therefore,the spherical contact form between walnut and cracking parts may be considered to design the structural shape of key components of walnut cracking machines,which was consistent with the analysis of compression test results.The comparison between experiment results and FEA results showed that the established FEA model can be used to analyze the mechanical properties of walnut.The research results can provide references for the structural design and optimization of key components of cracking machines for walnut or other nut crops. | Hong Zhang Liuyang Shen Haipeng Lan Yong Li Yang Liu Yurong Tang Wen Li | 2018 | International Journal of Agricultural and Biological Engineering2018，11，6： | 2 |
| 14 | Immunotoxicity and hepatotoxicity of PFOS and PFOA in tilapia(Oreochromis niloticus)显示文摘Perfluorinated organic compounds(PFOCs) are emerging persistent organic pollutants(POPs) widely distributed in the environment,wildlife and human.We studied the toxicology of perfluorooctane sulfonate(PFOS) and perfluorooctanoic acid(PFOA) on immunotoxicity and hepatotoxicity in primarily cultured hepatocytes of freshwater tilapia(Oreochromis niloticus).Cultured hepatocytes were exposed to PFOS or PFOA(0,10,20 and 30 mg/L) for 24,48,72,96,120 and 144 hours,respectively.Oral doses of these compounds that induce significantly detectable immunotoxicity and hepatotoxicity were employed in the study.In response to PFOS,the leukocytes,B cells,granulocytes,and macrophages among the isolation of intrahepatic immune cells(IHIC) from PFOS-treated tilapia produced significant levels of immune cells compared with that of the control group.The numbers of leukocytes,B cells,granulocytes,and macrophages for PFOS-treated tilapia increased with the incremental exposure concentration.Moreover,similar to the findings in PFOA toxicity effects,the erythropoietin levels in tilapia increased with the increase of the PFOS and PFOA concentrations.The lowest doses(10 mg/L) of PFOS exposure led to a marked inhibition in the hepatocyte viability in tilapia.Similarly,tilapia exposed to PFOA demonstrated a similar pattern,and a dose-dependent decrease in the hepatocyte viability was observed in the following treatment of PFOA.In the 72 h exposures,ethoxy-resorufin-O-deethylase(EROD) activity was significantly induced with the increase concentrations in tilapia liver(p<0.05).Tilapia showed a strong EROD induction in livers,and significantly difference in EROD activity was observed between control,PFOS and PFOA-exposed tilapias.The liver glycogen content showed that PFOS and PFOA exposure caused significant changes in the liver glycogen content,which depended on the duration of exposure.And it appeared that the decrease in blood glucose level during the acclimation was followed by significant increase in liver glycogen content in tilapia. | HAN Zhaoxiang LIU Yurong WU Dandan ZHU Zhen Lu Chunxia | 2012 | Chinese Journal Of Geochemistry2012，31，4： | 2 |
| 15 | Structurally tunable characteristics of ionic liquids for optimizing lithium plating/stripping via electrolyte engineering显示文摘Electrolyte chemistry offers the opportunity to regulate the solid electrolyte interphase(SEI) and Li^(+)solvation,which is considered to be crucial to the growth of lithium crystals for safe lithium metal batteries(LMBs).Structurally tunable characteristics of ionic liquids(ILs) from anion type,cationic substituent chain length and cationic substituents,will contribute this field.Here,we explore the influence mechanism of imidazole-based ILs as electrolyte additives on Li+solvation and the formation of SEI.ILs can participate into the formation of efficient SEI,together with cathode electrolyte interphase(CEI).Moreover,ILs can also regulate the sheath structure of Li^(+)solvation,to fasten the kinetics of Li.Furthermore,the imidazole-based cations with long alkyl chain can form an electrostatic shield around newly formed Li nucleus,and suppress further Li plating at this site.Under the optimized condition,the 1-octyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide([OMIm]TFSI) additive shows the best ability to enhance the electrochemical performance,endowing the Li||Li symmetric cell with a stable life(over800 h) at 0.5 mA cm^(-2) and the Li||LiNi_(0.6)Mn_(0.2)Co_(0.2)O_(2)(NMC622) full cell with a high capacity of 141.7 mAh g^(-1) after 200 cycles at 0.5 C. | Shihan Qi Jiandong Liu Jian He Huaping Wang Mingguang Wu Daxiong Wu Junda Huang Fang Li Xin Li Yurong Ren Jianmin Ma | 2021 | Journal of Energy Chemistry2021，30，12： | 2 |
| 16 | A systematic review of matrix metalloproteinase 9 as a biomarker of survival in patients with osteosarcoma显示文摘 | Hui Li Kun Zhang Li-hong Liu Yurong Ouyang Jie Bu Hong-bin Guo Tao Xiao | 2014 | Tumor Biology2014，，6： | 2 |
| 17 | A HIGH VELOCITY FEED UNIT DRIVEN BY LINEAR MOTOR显示文摘In order to realize high speed machining, the special requirements for feed transmission system of the CNC machine tool have to be satisfied. A high velocity feed unit driven by a induction linear motor is developed. The compositions of the high velocity CNC feed unit and main problems in the unit design are discussed. | Zhang Bolin Chen Yanji Li Zhiying Liu Yurong Luo Yong (Department of Mechanical and Electronical Engineering, Guangdong University of Technology) | 2000 | Chinese Journal of Mechanical Engineering2000，13，4： | 2 |
| 18 | A novel process for circle-like 3D mierostructures by two-step wet etching显示文摘 | Jiang Yurong Liu Guizhen Zhou Jian | 2009 | J Micromech Microeng2009，19，1： | 1 |
| 19 | H∞ filtering for uncertain stochastic time-delay systems with sector-bounded nonlinearities显示文摘 | WANG Zidong LIU Yurong LIU Xiaohui | | 0，，： | 1 |
| 20 | Stochastic stability of uncertain Hopfield neural networks with discrete and distributed delays显示文摘 | Zidong Wang Yurong Liu Karl Fraser Xiaohui Liu | 2006 | Physics Letters A2006，354，： | 1 |
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