|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome显示文摘Obstructive sleep apnea syndrome(OSAS)is a common breathing disorder in sleep in which the airways narrow or collapse during sleep,causing obstructive sleep apnea.The prevalence of OSAS continues to rise worldwide,particularly in middle-aged and elderly individuals.The mechanism of upper airway collapse is incompletely understood but is associated with several factors,including obesity,craniofacial changes,altered muscle function in the upper airway,pharyngeal neuropathy,and fluid shifts to the neck.The main characteristics of OSAS are recurrent pauses in respiration,which lead to intermittent hypoxia(IH)and hypercapnia,accompanied by blood oxygen desaturation and arousal during sleep,which sharply increases the risk of several diseases.This paper first briefly describes the epidemiology,incidence,and pathophysiological mechanisms of OSAS.Next,the alterations in relevant signaling pathways induced by IH are systematically reviewed and discussed.For example,IH can induce gut microbiota(GM)dysbiosis,impair the intestinal barrier,and alter intestinal metabolites.These mechanisms ultimately lead to secondary oxidative stress,systemic inflammation,and sympathetic activation.We then summarize the effects of IH on disease pathogenesis,including cardiocerebrovascular disorders,neurological disorders,metabolic diseases,cancer,reproductive disorders,and COVID-19.Finally,different therapeutic strategies for OSAS caused by different causes are proposed.Multidisciplinary approaches and shared decision-making are necessary for the successful treatment of OSAS in the future,but more randomized controlled trials are needed for further evaluation to define what treatments are best for specific OSAS patients. | Renjun Lv Xueying Liu Yue Zhang Na Dong Xiao Wang Yao He Hongmei Yue Qingqing Yin | 2023 | Signal Transduction and Targeted Therapy2023，8，6： | 8 |
| 2 | Strength and Stability Analysis of Deep Sea Drilling Risers显示文摘In order to analyze the influence of vortex-induced vibration on the strength and stability of marine drilling risers, a simplified analytical model was established and a method for calculating vortex-induced dynamic response was developed. A case study indicated that at primary resonance, first-order dynamic displacement response is greater than higher-order mode responses, but the influence of dynamic moment and shearing force of higher-order modes cannot be ignored. The natural frequency of risers decreased sharply with increasing length of the riser, but increased with increasing top tension. Various factors should be considered to avoid vortex-induced vibration in practical application, and the influence of vortex-induced vibration could be estimated by calculating the fatigue lifetime of riser. | Yang Jin Liu Caihong Liu Hanbin Xie Renjun Cao Shijing | 2007 | Petroleum Science2007，4，2： | 5 |
| 3 | Occurrence of human pathogenic bacteria carrying antibiotic resistance genes revealed by metagenomic approach: A case study from an aquatic environment显示文摘Antibiotic resistance genes(ARGs), human pathogenic bacteria(HPB), and HPB carrying ARGs are public issues that pose a high risk to aquatic environments and public health. Their diversity and abundance in water, intestine, and sediments of shrimp culture pond were investigated using metagenomic approach. A total of 19 classes of ARGs, 52 HPB species, and 7 species of HPB carrying ARGs were found. Additionally, 157, 104, and 86 subtypes of ARGs were detected in shrimp intestine, pond water, and sediment samples, respectively. In all the samples, multidrug resistance genes were the highest abundant class of ARGs. The dominant HPB was Enterococcus faecalis in shrimp intestine, Vibrio parahaemolyticus in sediments, and Mycobacterium yongonense in water, respectively. Moreover, E. faecalis(contig Intestine_364647)and Enterococcus faecium(contig Intestine_80272) carrying efr A, efr B and ANT(6)-Ia were found in shrimp intestine, Desulfosaricina cetonica(contig Sediment_825143) and Escherichia coli(contig Sediment_188430) carrying mex B and APH(3′)-IIa were found in sediments, and Laribacter hongkongensis(contig Water_478168 and Water_369477), Shigella sonnei(contig Water_880246),and Acinetobacter baumannii(contig Water_525520) carrying sul1, sul2, ere A, qac H, OXA-21, and mph D were found in pond water. Mobile genetic elements(MGEs) analysis indicated that horizontal gene transfer(HGT) of integrons, insertion sequences, and plasmids existed in shrimp intestine, sediment, and water samples, and the abundance of integrons was higher than that of other two MGEs. The results suggested that HPB carrying ARGs potentially existed in aquatic environments, and that these contributed to the environment and public health risk evaluation. | Renjun Zhou Shenzheng Zeng Dongwei Hou Jian Liu Shaoping Weng Jianguo He Zhijian Huang | 2019 | Journal of Environmental Sciences2019，31，6： | 5 |
| 4 | Metal-organic Chemical Vapor Deposition of GaSb/GaAs Quantum Dots: the Dependence of the Morphology on Growth Temperature and Vapour V/Ⅲ Ratio显示文摘 | YANG Haoyu LIU Renjun LU You WANG Liankai LI Tiantian LI Guoxing ZHANG Yuantao ZHANG Baolin | 2014 | Chemical Research in Chinese Universities2014，30，1： | 2 |
| 5 | Stability of the rarefaction wave for a two-fluid plasma model with diffusion显示文摘We study the large-time asymptotics of solutions toward the weak rarefaction wave of the quasineutral Euler system for a two-fluid plasma model in the presence of diffusions of velocity and temperature under small perturbations of initial data and also under an extra assumption θ_i,+/θ_e,+=θ_i,-/θ_e,-≥m_i/2m_e,namely, the ratio of the thermal speeds of ions and electrons at both far fields is not less than one half. Meanwhile,we obtain the global existence of solutions based on energy method. | DUAN RenJun LIU ShuangQian YIN HaiYan ZHU ChangJiang | 2016 | Science China Mathematics2016，59，1： | 2 |
| 6 | Peptide NGR Modified TiO_(2) Nanofiber Substrate for Circulating Tumor Cells Capture显示文摘The analysis of circulating tumor cells(CTCs)allows a noninvasive method of“real-time liquid biopsy”from the blood samples of cancer patients for the diagnosis of early-stage cancer,prognosis,and monitoring therapeutic response.In this study,we develop a simple,inexpensive,and reliable method that utilizes a small molecule peptide,the asparagine-glycine-arginine(NGR),as a capture probe for the selective enrichment and isolation of circulating tumor cells(CTCs).The multiscale TiO_(2) nanofibers are obtained by electrospinning and calcination.Bovine serum albumin(BSA)is decorated onto TiO_(2) nanofiber surfaces to inhibit non-target cell adhesion,while NGR peptides are conjugated onto the TiO_(2)-BSA surface through the glutaraldehyde(GA)to specifically capture the target cells.The TiO_(2)-BSA-NGR substrate exhibits a high capture sensitivity and efficiency from the mimical blood samples with PC-3 cancer cells as low as 10 cells/mL.The TiO_(2) nanofiber substrate can be a promising strategy for the capture and enumeration of CTCs in cancer progression monitoring. | Changchong Chen Zeen Wu Pi Ding Na Sun Hui Liu Yong Chen Zhili Wang Renjun Pei | 2020 | Advanced Fiber Materials2020，2，4： | 2 |
| 7 | Robust PID control design for permanent magnet synchronous motor a genetic approach显示文摘 | Jan Rongmaw Tseng Chungshi Liu Renjun | 2008 | Electric Power Systems Research2008，78，7： | 1 |
| 8 | Microbial community coexisting with harmful alga Karenia mikimotoi and microbial control of algal bloom in laboratory显示文摘Algicidal bacteria have been frequently isolated from algal blooming areas.However,knowledge regarding the microbial communities coexisting with microalgae and their potential application in preventing harmful algal blooms(HABs)is limited.In this study,we investigated the composition of the microbial community coexisting with harmful alga Karenia mikimotoi and its responses to algal control via nutrient stimulation or by adding algicidal strain in microcosms.The microorganisms inhabiting the K.mikimotoi culture consisted of 24 identifi ed phyla,including dominant Proteobacteria(relative abundance 76.24%±7.28%)and Bacteroidetes(22.67%±8.32%).Rhodobacteraceae,Phaeodactylibacter,and Maritimibacter predominated during the algal cultivation.Both the added nutrient and fermentation broth of algicidal strain Pseudoalteromonas QF1 caused a massive death of K.mikimotoi and substantial changes in the coexisting microbial community,in which Rhodobacteraceae and Phaeodactylibacter signifi cantly decreased,while Halomonas and Alteromonas increased.Core operational taxonomic units(OTUs)analysis indicated that 13 OTUs belonging to Rhodobacteraceae,Maritimibacter,Marivita,Nisaea,Phaeodactylibacter,Citreicella,Halomonas,Alteromonas,Marinobacter,Muricauda,and Pseudoalteromonas dominated the changes of the microbial communities observed in the K.mikimotoi culture with or without treatments.Collectively,this study indicated that microbial community inhabiting K.mikimotoi culture includes potential algicidal bacteria,and improves our knowledge about microbial community succession during biocontrol of K.mikimotoi via nutrient stimulation or by adding isolated algicidal strains. | Li SUN Peike GAO Yu LI Chao WANG Ning DING Junfeng CHEN Yuhao SONG Chunchen LIU Lun SONG Renjun WANG | 2022 | Journal of Oceanology and Limnology2022，40，3： | 1 |
| 9 | Analysis on the capture, behavior monitoring and death of the baiji ( Lipotes vexillifer) in the Shishou Semi-natural Reserve at Yangtze River China 显示文摘 | Liu Renjun Yang Jian Wang Ding Zhao Qingzhong Wei Zhuo Wang Xiaoqiang | 1997 | International Marine Biological Research lnstitute Report1997，8，： | 1 |
| 10 | Cement mortar with enhanced flexural strength and durability-related properties using in situ polymerized interpenetration network显示文摘ABSTRACT The low flexural strength and high brittleness of cementitious materials impair their service life in building structures.In this study,we developed a new polymer-modified mortar by in situ polymerization of acrylamide(AM)monomers during the cement setting,which enhanced the flexural and durable performances of mortars.The mechanical properties,micro-and-pore structures,hydrated products,interactions between cement hydrates and polyacrylamide(PAM),and durability-related properties of the mortars were investigated comprehensively.Mortars with 5%PAM exhibited the best performance in terms of flexural strength among all the mixtures.The mechanical strength of cement pastes modified by in situ polymerization of AM monomers was significantly superior to those modified by PAM.The chemical interactions between the polymer molecules and cement hydrates together with the formation of polymer films glued the cement hydrates and polymers and resulted in an interpenetrating network structure,which strengthened the flexural strength.Reductions in porosity and calcium hydroxide content and improvement in capillary water absorption were achieved with the addition of PAM.Finally,the chloride resistance was significantly enhanced with the incorporation of PAM. | Qing LIU Renjun LIU Qiao WANG Rui LIANG Zongjin LI Guoxing SUN | 2021 | Frontiers of Structural and Civil Engineering2021，15，1： | 1 |
| 11 | A NEW APPROACH OF AVAILABLE TRANSFER CAPABILITY INCORPORATING WIND GENERATION显示文摘 | Xiaojiao TONG Chunping LIU Xiao LUO Renjun ZHOU | 2010 | Journal of Systems Science & Complexity2010，23，5： | 1 |
| 12 | A Study of the Distribution and Variability of Cloud Water Using ISCCP, SSM/I Cloud Product, and Reanalysis Datasets显示文摘 | Heng Zhiwei Fu Yunfei Liu Guosheng Zhou Renjun Wang Yu Yuan Renmin Guo Jingchao Dong Xue | 2014 | Journal of Climate2014，，9： | 1 |
| 13 | The Vlasov-Poisson-Boltzmann System without Angular Cutoff显示文摘 | Renjun Duan Shuangqian Liu | 2013 | Communications in Mathematical Physics2013，，1： | 1 |
| 14 | 7-Ketocholesteryl-9-carboxynonanoate enhances ATP binding cassette transporter A1 expression mediated by PPARγ in THP-1 macrophages显示文摘 | Yan Chi Le Wang Yuanyuan Liu Yanhua Ma Renjun Wang Xiaofei Han Hui Qiao Jiabin Lin Eiji Matsuura Shuqian Liu Qingping Liu | 2014 | Atherosclerosis2014，，： | 1 |
| 15 | Analysis of the Lost Circulation Problem显示文摘The well-known“lost circulation”problem refers to the uncontrolled flow of whole mud into a formation.In order to address the problem related to the paucity of available data,in the present study,a model is introduced for the lost-circulation risk sample profile of a drilled well.The model is built taking into account effective data(the Block L).Then,using a three-dimensional geological modeling software,relying on the variation function and sequential Gaussian simulation method,a three-dimensional block lost-circulation risk model is introduced able to provide relevant information for regional analyses. | Xingquan Zhang Renjun Xie Kuan Liu Yating Li Yuqiang Xu | 2023 | Fluid Dynamics & Materials Processing2023，19，6： | 0 |
| 16 | Analysis of the Microstructure of a Failed Cement Sheath Subjected to Complex Temperature and Pressure Conditions显示文摘One of the main obstacles hindering the exploitation of high-temperature and high-pressure oil and gas is the sealing integrity of the cement sheath.Analyzing the microstructure of the cement sheath is therefore an important task.In this study,the microstructure of the cement sheath is determined using a CT scanner under different temperature and pressure conditions.The results suggest that the major cause of micro-cracks in the cement is the increase in the casing pressure.When the micro-cracks accumulate to a certain extent,the overall structure of the cement sheath is weakened,resulting in gas channeling,which poses a direct threat to the safe production of oil and gas.A change in the casing temperature has a limited effect on the microstructure of the cement sheath. | Zhiqiang Wu Yi Wu Renjun Xie Jin Yang Shujie Liu Qiao Deng | 2023 | Fluid Dynamics & Materials Processing2023，19，2： | 0 |
| 17 | SINO-JAPANESE JOINT RESEARCH ON THE CONSERVATION OF BAIJI DOLPHINS显示文摘Since 1988, the Japan Enoshima Aquarium (JEA) and the Institute of Hydrobiology of Chinese Academy of Sciences(IHCAS) have carried out long-term joint research on the conservation of Baiji dolphins (Lipotes vexillifer). According to the research, the population of Baiji dolphins has been decreasing rapidly from 300 in 1986 to less than 100 at present due to environmental deterioration of the Yangtze River. Since it is impossible to conserve the species in the river, as many as possible of the dolphins should be collected and transferred | Liu Renjun(Institute of Hydrobiology, the CAS, Wuchan)Yukiko Hori(Enoshima Aquarium, Japan) | 1997 | Bulletin of the Chinese Academy of Sciences1997，11，2： | 0 |
| 18 | Feasibility Analysis and Policy Recommendations for Production of Hybrid Rice Seed in Foreign Countries显示文摘In the economic new normal,production of hybrid rice seed in foreign countries is the necessity for reducing farmland area occupied by seed production,for ensuring national grain security,realizing cost reducing and quality improving of hybrid rice seed,strengthening competitive power at international market,guiding seed industry of China to go out,building transnational seed groups with core competitive power,establishing close relationship with developing countries,promoting the construction of One Belt One Road strategy,serving overall situation of diplomacy,and setting up excellent international image. It is feasible to produce hybrid seed in foreign countries considering( i) high overall national strength of China,( ii) rapid and healthy growth of China's seed industry and increasingly mature hybrid rice seed production technologies,( iii) excellent climatic conditions of foreign host countries of seed production,and( iv) low land and labor price of foreign host countries of seed production. However,there are social and policy risks,technology and trade barrier risks,market,production,and other risks for production of hybrid rice seed in foreign countries. In view of these,it came up with recommendations,including allowing delivering parent seeds of hybrid rice to foreign countries,allowing delivering hybrid rice seed to China,solving the problem of ' opening in protection,and protection in opening',and formulating a package of support policies. | Hongbo DUAN Qianyu YANG Xiangping LIU Zhixin LI Renjun WANG | 2016 | Asian Agricultural Research2016，8，10： | 0 |
| 19 | Heat Transfer Problem for the Boltzmann Equation in a Channel with Diffusive Boundary Condition显示文摘In this paper,the authors study the 1 D steady Boltzmann flow in a channel.The walls of the channel are assumed to have vanishing velocity and given temperaturesθ0andθ1.This problem was studied by Esposito-Lebowitz-Marra(1994,1995)where they showed that the solution tends to a local Maxwellian with parameters satisfying the compressible Navier-Stokes equation with no-slip boundary condition.However,a lot of numerical experiments reveal that the fluid layer does not entirely stick to the boundary.In the regime where the Knudsen number is reasonably small,the slip phenomenon is significant near the boundary.Thus,they revisit this problem by taking into account the slip boundary conditions.Following the lines of[Coron,F.,Derivation of slip boundary conditions for the Navier-Stokes system from the Boltzmann equation,J.Stat.Phys.,54(3-4),1989,829-857],the authors will first give a formal asymptotic analysis to see that the flow governed by the Boltzmann equation is accurately approximated by a superposition of a steady CNS equation with a temperature jump condition and two Knudsen layers located at end points.Then they will establish a uniform L∞estimate on the remainder and derive the slip boundary condition for compressible Navier-Stokes equations rigorously. | Renjun DUAN Shuangqian LIU Tong YANG Zhu ZHANG | 2022 | Chinese Annals of Mathematics,Series B2022，43，6： | 0 |
| 20 | Artificially Rearing the Baiji, Lipotes Vexillifer, for Twenty-one Years显示文摘The history of artificially rearing cetacean specieshas been over a hundred in the world. Rearing cetaceanspecies in captivity can supply not only a kind of interesting entertainment, but also good conditions for intensively researching, breeding and conserving | Liu Renjun Zhang Xianfeng(Institute of Hydrobiology, Chinese Academy of Sciences , Wuhan430072) | 2002 | Science Foundation in China2002，10，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员