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| 1 | The Sunway TaihuLight supercomputer: system and applications显示文摘The Sunway Taihu Light supercomputer is the world's first system with a peak performance greater than 100 PFlops. In this paper, we provide a detailed introduction to the Taihu Light system. In contrast with other existing heterogeneous supercomputers, which include both CPU processors and PCIe-connected many-core accelerators(NVIDIA GPU or Intel Xeon Phi), the computing power of Taihu Light is provided by a homegrown many-core SW26010 CPU that includes both the management processing elements(MPEs)and computing processing elements(CPEs) in one chip. With 260 processing elements in one CPU, a single SW26010 provides a peak performance of over three TFlops. To alleviate the memory bandwidth bottleneck in most applications, each CPE comes with a scratch pad memory, which serves as a user-controlled cache. To support the parallelization of programs on the new many-core architecture, in addition to the basic C/C++and Fortran compilers, the system provides a customized Sunway Open ACC tool that supports the Open ACC2.0 syntax. This paper also reports our preliminary efforts on developing and optimizing applications on the Taihu Light system, focusing on key application domains, such as earth system modeling, ocean surface wave modeling, atomistic simulation, and phase-field simulation. | Haohuan FU Junfeng LIAO Jinzhe YANG Lanning WANG Zhenya SONG Xiaomeng HUANG Chao YANG Wei XUE Fangfang LIU Fangli QIAO Wei ZHAO Xunqiang YIN Chaofeng HOU Chenglong ZHANG Wei GE Jian ZHANG Yangang WANG Chunbo ZHOU Guangwen YANG | 2016 | Science China(Information Sciences)2016，59，7： | 45 |
| 2 | Genome-Wide Association Studies of Image Traits Reveal Genetic Architecture of Drought Resistance in Rice显示文摘理解植物怎么对干旱作出回应能有益于繁殖的干旱抵抗(医生) 。用一台非破坏性的 phenotyping 设备,为 507 米饭就职的 51 个基于图象的特点(i 特点) 被提取。这些 i 特点能被用来监视干旱回答 ? 并且高评估医生可遗传性和这些特点的大变化在自然人口在干旱应力下面被观察。染色体宽的协会研究(GWAS )?i 特点和传统的医生特点识别了 470 协会 loci,某包含知道医生相关的基因。这 470 loci, 443 loci (94%) 用 i 特点被识别, 437 loci (93%) 与以前报导的医生相关的量的特点 loci,和 313 loci (66.6%)co 局部性被 GWAS reproducibly 在不同的年里识别。协会网络,基于 GWAS 建立了结果,揭示中心 i 特点和中心 loci。这表明把的可行性和必要性复杂医生特点进可继承、简单的 i 特点。作为原则的证明,我们说明了这条综合途径的力量以前识别 unreported 医生相关的基因。OsPP15 与中心 i 特点被联系,并且它在医生的角色被基因转变实验证实。而且, i 特点能被用于医生连接分析,并且 69 个 i 特点地点协会被 recombinant 的 GWAS 和连接分析识别生来的线人口。最后,我们证实了 i 特点的关联在这个领域里搀。我们的学习为医生为原因的基因的基因解剖和发现提供一条有希望的新奇途径。 | Zilong Guo Wanneng Yang Yu Chang Xiaosong Ma Haifu Tu Fang Xiong Ni Jiang Hui Feng Chenglong Huang Peng Yang Hu Zhao Guoxing Chen Hongyan Liu Lijun Luo Honghong Hu Qian Liu Lizhong Xiong | 2018 | Molecular Plant2018，11，6： | 21 |
| 3 | Determination of rice panicle numbers during heading by multi-angle imaging显示文摘Plant phenomics has the potential to accelerate progress in understanding gene functions and environmental responses. Progress has been made in automating high-throughput plant phenotyping. However, few studies have investigated automated rice panicle counting. This paper describes a novel method for automatically and nonintrusively determining rice panicle numbers during the full heading stage by analyzing color images of rice plants taken from multiple angles. Pot-grown rice plants were transferred via an industrial conveyer to an imaging chamber. Color images from different angles were automatically acquired as a turntable rotated the plant. The images were then analyzed and the panicle number of each plant was determined. The image analysis pipeline consisted of extracting the i2 plane from the original color image, segmenting the image, discriminating the panicles from the rest of the plant using an artificial neural network, and calculating the panicle number in the current image. The panicle number of the plant was taken as the maximum of the panicle numbers extracted from all 12 multi-angle images. A total of 105 rice plants during the full heading stage were examined to test the performance of the method. The mean absolute error of the manual and automatic count was 0.5, with 95.3% of the plants yielding absolute errors within ± 1. The method will be useful for evaluating rice panicles and will serve as an important supplementary method for high-throughput rice phenotyping. | Lingfeng Duan Chenglong Huang Guoxing Chen Lizhong Xiong Qian Liu Wanneng Yang | 2015 | The Crop Journal2015，3，3： | 18 |
| 4 | A newly discovered Gigantopithecus fauna from Sanhe Cave, Chongzuo, Guangxi, South China显示文摘Among the most important faunas in the Late Cenozoic, the Gigantopithecus faunas have received a good deal of attention. The Gigantopithecus fauna recently discovered in Sanhe Cave consists of more than 80 mammal species, including cf. Hominidae, Pongo sp., Hylobates sp., Sinomastodon yangzien-sis, Stegodon preorientalis, Cervavitus fenqii, Dicoryphochoerus ultimus and Sus xiaozhu. It is the southernmost Gigantopithecus fauna found so far in China. Its geological age is estimated to be Early Pleistocene based on the fauna and stratigraphic correlation. The significant increase in the estimated body sizes of Ailuropoda, Gigantopithecus and Tapirus shows that the Sanhe fauna is middle Early Pleistocene, later than those from Wushan and Liucheng (early Early Pleistocene). Paleomagnetic dating of the fossil-bearing strata in Sanhe Cave gives an age of approximately 1.2 Ma. The fauna is characterized by tropical-subtropical forest types, including Pongo sp., Tupaia sp., Ia sp., Typhlomys intermedius, etc., and it lacks Palaearctic types. It is a typical tropical forest fauna, suggesting an en-vironment with a lush forest and a warm and humid climate. The discovery of the Sanhe Gigantopith-ecus fauna is significant for establishing the chronological stages of the Gigantopithecus faunas in China, and for discussing their origin, evolution and dynamics. | JIN ChangZhu QIN DaGong PAN WenShi TANG ZhiLu LIU JinYi WANG Yuan DENG ChengLong ZHANG YingQi DONG Wei TONG HaoWen | 2009 | Chinese Science Bulletin2009，54，5： | 14 |
| 5 | Astronomical tuning and magnetostratigraphy of Neogene biogenic reefs in Xisha Islands, South China Sea显示文摘Biogenic reefs are one of two major depositional types in the South China Sea, and are constructed by coral, algae and bryozoa. The West Pacific is a major area of biogenic reef development and plays a critical role in the global carbon cycle. However, the lack of geochronological studies in previous works inhibits our understanding of their contributions. Herein, we conduct a cyclostratigraphic and magnetostratigraphic study on Neogene biogenic reefs using the XK–1 core that was drilled at the Shidao Island,Xisha(Paracel) Islands. The main findings of this study are:(1) the establishment of reliable magentostratigraphy for Ledong, Huangliu, Meishan and Sanya Formations;(2) the magnetic susceptibility variation can be inferred as growth index and tuned to the 405–ka long eccentricity cycle;(3) the astronomical geochronology suggests that the bottom ages for Ledong, Yinggehai, Huangliu, Meishan,and Sanya Formations are 2.2 Ma, 5.7 Ma, 10.4 Ma, 16.6 Ma, and 24.3 Ma, respectively; and (4) Earth's eccentricity and obliquity played predominant roles in biogenic reef establishment on orbital to tectonic timescales. Thus, the reported geochronology offers an opportunity to test the contributions of various factors and hypothesize their roles in the global carbon cycle in future. | Liang Yi Zhimin Jian Xinyu Liu Youhua Zhu Daojun Zhang Zhenfeng Wang Chenglong Deng | 2018 | Science Bulletin2018，63，9： | 12 |
| 6 | The levels, sources and reactivity of volatile organic compounds in a typical urban area of Northeast China显示文摘Air concentrations of volatile organic compounds(VOCs) were continually measured at a monitoring site in Shenyang from 20 August to 16 September 2017. The average concentrations of alkanes, alkenes, aromatics and carbonyls were 28.54, 6.30, 5.59 and9.78 ppbv, respectively. Seven sources were identified by the Positive Matrix Factorization model based on the measurement data of VOCs and CO. Vehicle exhaust contributed the most(36.15%) to the total propene-equivalent concentration of the measured VOCs,followed by combustion emission(16.92%), vegetation emission and secondary formation(14.33%), solvent usage(10.59%), petrochemical industry emission(9.89%), petrol evaporation(6.28%), and liquefied petroleum gas(LPG) usage(5.84%). Vehicle exhaust, solvent usage and combustion emission were found to be the top three VOC sources for O_3 formation potential, accounting for 34.52%, 16.55% and 11.94%, respectively. The diurnal variation of the total VOCs from each source could be well explained by their emission characteristics,e.g., the two peaks of VOC concentrations from LPG usage were in line with the cooking times for breakfast and lunch. Wind rose plots of the VOCs from each source could reveal the possible distribution of the sources around the monitoring site. The O_3 pollution episodes during the measurement period were found to be coincident with the elevation of VOCs, which was mainly due to the air parcel from the southeast direction where petrochemical industry emission was found to be dominant, suggesting that the petrochemical industry emission from the southeast was probably a significant cause of O_3 pollution in Shenyang. | Zhuobiao Ma Chengtang Liu Chenglong Zhang Pengfei Liu Can Ye Chaoyang Xue Di Zhao Jichen Sun Yiming Du Fahe Chai Yujing Mu | 2019 | Journal of Environmental Sciences2019，31，5： | 12 |
| 7 | Seasonal and diurnal variations of atmospheric peroxyacetyl nitrate, peroxypropionyl nitrate, and carbon tetrachloride in Beijing显示文摘Atmospheric peroxyacetyl nitrate(PAN), peroxypropionyl nitrate(PPN), and carbon tetrachloride(CCl4) were measured from September 2010 to August 2011 in Beijing. PAN exhibited low values from mid-autumn to early spring(October to March) with monthly average concentrations ranging from 0.28 to 0.73 ppbV, and increased from early spring to summer(March to August), ranging from 1.37–3.79 ppbV. The monthly variation of PPN was similar to PAN, with low values(below detection limit to 0.18 ppbV) from mid-autumn to early spring, and a monthly maximum in September(1.14 ppbV). The monthly variation of CCl4was tightly related to the variation of temperature, exhibiting a minimum in winter(69.3 pptV) and a maximum of 180.6 pptV in summer. Due to weak solar intensity and short duration, PAN and O3showed no distinct diurnal patterns from morning to night during winter, whereas for other seasons, they both exhibited maximal values in the late afternoon(ca. 15:00 to 16:00 local time) and minimal values during early morning and midnight. Good linear correlations between PAN and PPN were found in autumn(R = 0.91), spring(R = 0.94), and summer(R = 0.81), with slopes of 0.130, 0.222, and 0.133, respectively, suggesting that anthropogenic hydrocarbons dominated the photochemical formation of PANs in Beijing. Positive correlation between PAN and O3 in summer with the low slopes( O3 / PAN) ranging from 9.92 to 18.0 indicated serious air pollution in Beijing, and strong negative correlation in winter reflected strong O3consumption by NO titration and less thermal decompositin of PAN. | Gen Zhang Yujing Mu Junfeng Liu Chenglong Zhang Yuanyuan Zhang Yujie Zhang Hongxing Zhang | 2014 | Journal of Environmental Sciences2014，26，1： | 11 |
| 8 | Terahertz metasurface zone plates with arbitrary polarizations to a fixed polarization conversion显示文摘Metasurfaces that can realize the polarization manipulation of electromagnetic waves on the sub-wavelength scale have become an emerging research field.Here,a novel strategy of combining the metasurface and Fresnel zone plate to form a metasurface zone plate is proposed to realize the conversion from nearly arbitrary polarizations to a fixed polarization.Specifically,when one polarized wave is incident on adjacent ring zones constructed by different types of meta-atoms,the transmitted waves generated by odd-numbered and even-numbered ring zones converge at the same focus and superimpose to generate a fixed polarized wave.As function demonstrations,we have designed two types of metasurface zone plates:one is a focused linear polarizer,and the other can convert nearly arbitrary polarized waves into focused circularly polarized waves.The simulated and measured results are consistent with theoretical expectations,suggesting that the proposed concept is flexible and feasible.Our work provides an alternative platform for polarization manipulation and may vigorously promote the development of polarization photonic devices. | Zhen Yue Jitao Li Jie Li Chenglong Zheng Jingyu Liu Guocui Wang Hang Xu Mingyang Chen Yating Zhang Yan Zhang Jianquan Yao | 2022 | Opto-Electronic Science2022，1，3： | 9 |
| 9 | Dynamic phase assembled terahertz metalens for reversible conversion between linear polarization and arbitrary circular polarization显示文摘If a metalens integrates the circular polarization(CP)conversion function,the focusing lens together with circular-polariz-ing lens(CPL)in traditional cameras may be replaced by a metalens.However,in terahertz(THz)band,the reported metalenses still do not obtain the perfect and strict single-handed CP,because they were constructed via Pancharatnam-Berry phase so that CP conversion contained both left-handed CP(LCP)and right-handed CP(RCP)components.In this paper,a silicon based THz metalens is constructed using dynamic phase to obtain single-handed CP conversion.Also,we can rotate the whole metalens at a certain angle to control the conversion of multi-polarization states,which can simply manipulate the focusing for incident linear polarization(LP)THz wave in three polarization conversion states,in-cluding LP without conversion,LCP and RCP.Moreover,the polarization conversion behavior is reversible,that is,the THz metalens can convert not only the LP into arbitrary single-handed CP,but also the LCP and RCP into two perpen-dicular LP,respectively.The metalens is expected to be used in advanced THz camera,as a great candidate for tradi-tional CPL and focusing lens group,and also shows potential application in polarization imaging with discriminating LCP and RCP. | Jitao Li Guocui Wang Zhen Yue Jingyu Liu Jie Li Chenglong Zheng Yating Zhang Yan Zhang Jianquan Yao | 2022 | Opto-Electronic Advances2022，5，1： | 9 |
| 10 | Evidence of fire use of late Pleistocene humans from the Huanglong Cave, Hubei Province, China显示文摘Since 2004, three excavations have been carried out at a late Pleistocene human fossil site of Huanglong Cave in Yunxi County, Hubei Province of China, which unearthed seven human teeth, dozens of stone tools, mammal fossils and other evidence indicating human activities. During the third excavation in 2006, in the same layer as the human teeth, we found some patches of black materials embed- ded in the deposit. We doubted that this black deposit layer is the remains of burning or even human use of fire at the cave. To further explore the possibility of human fire use at the Huanglong Cave, we examined samples directly taken from the black deposit layer and compared them with samples taken from several places in the cave using three methods: micromorphology, element content determination and deposit temperature analysis. Our results indicate that the contents of carbon element in the black deposit reach 64.59%―73.29%. In contrast, contents of carbon element of the comparative samples from other parts in the cave are only 5.82%―9.49%. The micromorphology analysis of the black deposit samples reveals a plant structure like axial parenchyma, fibrocyte, uniseriate ray and vessel. High-temperature magnetic susceptibility measurements suggest that the stratum possibly underwent a high temperature in the nature. Based on these lab analyses, we are sure that the black layer in the Huanglong Cave is the remains of fire and combustion did occur in the cave 100000 years ago. Taking other evidence of human activities found in the Huanglong Cave into consideration, we believe that the evidence of fire from the Huanglong Cave was caused by the human activities of controlled use of fire. | LIU Wu WU XianZhu LI YiYin DENG ChengLong WU XiuJie PEI ShuWen | 2009 | Chinese Science Bulletin2009，54，2： | 8 |
| 11 | In-situ cosmogenic ^(36)Cl denudation rates of carbonates in Guizhou karst area显示文摘This study quantifies surface denudation of carbonate rocks by the first application of in-situ cosmogenic36Cl in China. Concentrations of natural Cl and in-situ cosmogenic36Cl in bare carbonates from Guizhou karst areas were measured with isotope dilution by accelerator mass spectrometer. The Cl concentration varied from 16 to 206 ppm. The 36Cl concentrations were in range of (0.8-2.4)106 atom g-1 , resulting in total denudation rates of 20-50 mm ka-1 that averaged over a 104-105 a timescale. The 36Cl-denudation rates showed roughly a negative correlation with the local mean temperature. This preliminary observation may suggest the variations of proportions of chemical weathering and physical erosion in denudation process, depending upon local climatic conditions. | XU Sheng LIU CongQiang FREEMAN Stewart LANG YunChao SCHNABEL Christoph TU ChengLong WILCKEN Klaus ZHAO ZhiQi | 2013 | Chinese Science Bulletin2013，58，20： | 7 |
| 12 | Nondestructive 3D Image Analysis Pipeline to Extract Rice Grain Traits Using X-Ray Computed Tomography显示文摘The traits of rice panicles play important roles in yield assessment,variety classification,rice breeding,and cultivation management.Most traditional grain phenotyping methods require threshing and thus are time-consuming and labor-intensive;moreover,these methods cannot obtain 3D grain traits.In this work,based on X-ray computed tomography,we proposed an image analysis method to extract twenty-two 3D grain traits.After 104 samples were tested,the R^(2) values between the extracted and manual measurements of the grain number and grain length were 0.980 and 0.960,respectively.We also found a high correlation between the total grain volume and weight.In addition,the extracted 3D grain traits were used to classify the rice varieties,and the support vector machine classifier had a higher recognition accuracy than the stepwise discriminant analysis and random forest classifiers.In conclusion,we developed a 3D image analysis pipeline to extract rice grain traits using X-ray computed tomography that can provide more 3D grain information and could benefit future research on rice functional genomics and rice breeding. | Weijuan Hu Can Zhang Yuqiang Jiang Chenglong Huang Qian Liu Lizhong Xiong Wanneng Yang Fan Chen | 2020 | Plant Phenomics2020，2，1： | 6 |
| 13 | Expressions of apoptosis-related proteins in rats with focal cerebral ischemia after Angong Niuhuang sticker point application显示文摘In this study, we extracted and purified components in the Angong Niuhuang pill. Then we applied transdermal enhancers to Angong Niuhuang stickers by modern technology. The Angong Niuhuang sticker includes extracts from curcuma, berberine hydrochloride, baicalin, geniposide, borneol, and musk. Angong Niuhuang stickers at different point application doses (1.35, 2.7, and 5.4 g/kg) were administered to Dazhui (DU14), Qihai (RN6) and Mingmen (DU4). Rats in the different dose point application and acupuncture groups were continuously administered for 7 days. Then a middle cerebral artery occlusion model was prepared for simulating human cerebral ischemia. Twelve hours later, expressions of Bcl-2, Bax and p53 protein in hippocampal CA1 were detected with immunohistochemistry. The expression level of Bcl-2, an anti-apoptotic protein, significantly increased in the high-, medium- and low-dose point application groups and the acupuncture group, while the expression of the pro-apoptotic proteins, Bax and p53, significantly decreased compared with the middle cerebral artery occlusion rats; and the Bcl-2/Bax ratio was significantly increased. The difference was noticeable for the high-dose point application group, which showed statistical difference compared with the low-dose point application group and the acupuncture group. Our experimental findings indicate that point application with Angong Niuhuang stickers promotes the expression of Bcl-2, and inhibits the expressions of Bax and p53 in the hippocampal CA1 area of rats after focal cerebral ischemia. Thus, point application of Angong Niuhang stickers protects brain tissues from cerebral ischemia. | Dongshu Zhang Maodong Fu Chenglong Song Caiyun Wang Xiaochun Lin Yuanliang Liu | 2012 | Neural Regeneration Research2012，7，30： | 6 |
| 14 | Coseismic response of groundwater level in the Three Gorges well network and its relationship to aquifer parameters显示文摘The 12 May 2008 Ms 8.0 Wenchuan earthquake caused notable changes in the water levels of wells in the Three Gorges area. This work examines the relationship between these coseismic changes in water level and the changes in aquifer parameters. Three wells in the area with good responses to earth tide were chosen for analysis. Water-level data from February to June 2008 were used to calculate the aquifer transmissivity, permeability and specific storage of the rocks, and analyze the relationship between the coseismic responses of the wells and their aquifer parameters. The results show that the Wenchuan earthquake changed these parameters considerably, thereby controlling co- and postseismic variations of water level. The values of these parameters prior to the earthquake are linearly related with the amplitudes of coseismic variations in water level. The larger the aquifer transmissivity, the more remarkable the coseismic change in water level. During the earthquake, changes in aquifer parameters were found to be associated with coseismic variations in water level, with the larger changes occurring when the coseismic variation in water level was larger. The tectonic setting has a certain degree of influence on the co- and postseismic changes in water level. The permeability structures of the fault zone appear to determine the manner of coseismic variation in water level. Moreover, it seems that the water level in wells where groundwater converges more easily can recover faster following an earthquake. Insight from this study helps to improve understanding of the characteristics of water-level changes caused by earthquakes. | SHI ZheMing WANG GuangCai LIU ChengLong MEI JianChang WANG JinWei FANG HuiNa | 2013 | Chinese Science Bulletin2013，58，25： | 6 |
| 15 | Abnormal interruption of water flow from an artesian well prior to 2008 Wenchuan earthquake显示文摘Water flow from an artesian well stopped on December 17,2007 but recovered when the Wenchuan Ms 8.0 earthquake occurred on May 12,2008.This well is located 90 km south of the epicenter in an extensional tectonic setting,where similar changes of water level and resistivity were observed at two other nearby sites.Our investigation suggests that this phenomenon was not caused by environmental disturbances,such as drought or borehole-drilling activity,but might be a precursor to the earthquake. | Liu Chenglong Che Yongtai Xu Yinju Shi Zheming Yang Xianhe | 2011 | Geodesy and Geodynamics2011，2，2： | 5 |
| 16 | Intelligent metasurface imager and recognizer显示文摘There is an increasing need to remotely monitor people in daily life using radio-frequency probe signals.However,conventional systems can hardly be deployed in real-world settings since they typically require objects to either deliberately cooperate or carry a wireless active device or identification tag.To accomplish complicated successive tasks using a single device in real time,we propose the simultaneous use of a smart metasurface imager and recognizer,empowered by a network of artificial neural networks(ANNs)for adaptively controlling data flow.Here,three ANNs are employed in an integrated hierarchy,transforming measured microwave data into images of the whole human body,classifying specifically designated spots(hand and chest)within the whole image,and recognizing human hand signs instantly at a Wi-Fi frequency of 2.4 GHz.Instantaneous in situ full-scene imaging and adaptive recognition of hand signs and vital signs of multiple non-cooperative people were experimentally demonstrated.We also show that the proposed intelligent metasurface system works well even when it is passively excited by stray Wi-Fi signals that ubiquitously exist in our daily lives.The reported strategy could open up a new avenue for future smart cities,smart homes,human-device interaction interfaces,health monitoring,and safety screening free of visual privacy issues. | Lianlin Li Ya Shuang Qian Ma Haoyang Li Hanting Zhao Menglin Wei Che Liu Chenglong Hao Cheng-Wei Qiu Tie Jun Cui | 2019 | Light(Science & Applications)2019，8，1： | 5 |
| 17 | Terahertz wavefront shaping with multi-channel polarization conversion based on all-dielectric metasurface显示文摘Polarization manipulation of electromagnetic wave or polarization multiplexed beam shaping based on metasurfaces has been reported in various frequency bands.However,it is difficult to shape the beam with multi-channel polarization conversion in a single metasurface.Here,we propose a new method for terahertz wavefront shaping with multi-channel polarization conversion via all-silicon metasurface,which is based on the linear shape birefringence effect in spatially interleaved anisotropic meta-atoms.By superimposing the eigen-and non-eigen-polarization responses of the two kinds of meta-atoms,we demonstrate the possibility for high-efficiency evolution of several typical polarization states with two independent channels for linearly polarized waves.The measured polarization conversion efficiency is higher than 70%in the range of 0.9–1.3 THz,with a peak value of 89.2%at 1.1 THz.In addition,when more other polarization states are incident,combined with the integration of sub-arrays,we can get more channels for both polarization conversion and beam shaping.Simulated and experimental results verify the feasibility of this method.The proposed method provides a new idea for the design of terahertz multi-functional metadevices. | JIE LI CHENGLONG ZHENG JITAO LI GUOCUI WANG JINGYU LIU ZHEN YUE XUANRUO HAO YUE YANG FUYU LI TINGTING TANG YATING ZHANG YAN ZHANG JIANQUAN YAO | 2021 | Photonics Research2021，9，10： | 5 |
| 18 | Challenges and strategies for in situ endothelialization and long-term lumen patency of vascular grafts显示文摘Vascular diseases are the most prevalent cause of ischemic necrosis of tissue and organ,which even result in dysfunction and death.Vascular regeneration or artificial vascular graft,as the conventional treatment modality,has received keen attentions.However,small-diameter(diameter<4 mm)vascular grafts have a high risk of thrombosis and intimal hyperplasia(IH),which makes long-term lumen patency challengeable.Endothelial cells(ECs)form the inner endothelium layer,and are crucial for anti-coagulation and thrombogenesis.Thus,promoting in situ endothelialization in vascular graft remodeling takes top priority,which requires recruitment of endothelia progenitor cells(EPCs),migration,adhesion,proliferation and activation of EPCs and ECs.Chemotaxis aimed at ligands on EPC surface can be utilized for EPC homing,while nanofibrous structure,biocompatible surface and cell-capturing molecules on graft surface can be applied for cell adhesion.Moreover,cell orientation can be regulated by topography of scaffold,and cell bioactivity can be modulated by growth factors and therapeutic genes.Additionally,surface modification can also reduce thrombogenesis,and some drug release can inhibit IH.Considering the influence of macrophages on ECs and smooth muscle cells(SMCs),scaffolds loaded with drugs that can promote M2 polarization are alternative strategies.In conclusion,the advanced strategies for enhanced long-term lumen patency of vascular grafts are summarized in this review.Strategies for recruitment of EPCs,adhesion,proliferation and activation of EPCs and ECs,anti-thrombogenesis,anti-IH,and immunomodulation are discussed.Ideal vascular grafts with appropriate surface modification,loading and fabrication strategies are required in further studies. | Yu Zhuang Chenglong Zhang Mengjia Cheng Jinyang Huang Qingcheng Liu Guangyin Yuan Kaili Lin Hongbo Yu | 2021 | Bioactive Materials2021，6，6： | 5 |
| 19 | Concept of the solar ring mission:An overview显示文摘The concept of the Solar Ring mission was gradually formed from L5/L4 mission concept, and the proposal of its pre-phase study was funded by the National Natural Science Foundation of China in November 2018 and then by the Strategic Priority Program of Chinese Academy of Sciences in space sciences in May 2019. Solar Ring mission will be the first attempt to routinely monitor and study the Sun and inner heliosphere from a full 360-degree perspective in the ecliptic plane. The current preliminary design of the Solar Ring mission is to deploy six spacecraft, grouped in three pairs, on a sub-AU orbit around the Sun. The two spacecraft in each group are separated by about 30?and every two groups by about 120?. This configuration with necessary science payloads will allow us to establish three unprecedented capabilities:(1) determine the photospheric vector magnetic field with unambiguity,(2) provide 360-degree maps of the Sun and the inner heliosphere routinely, and(3) resolve the solar wind structures at multiple scales and multiple longitudes. With these capabilities, the Solar Ring mission aims to address the origin of solar cycle, the origin of solar eruptions, the origin of solar wind structures and the origin of severe space weather events. The successful accomplishment of the mission will advance our understanding of the star and the space environment that hold our life and enhance our capability of expanding the next new territory of human. | WANG YuMing JI HaiSheng WANG YaMin XIA LiDong SHEN ChengLong GUO JingNan ZHANG QuanHao HUANG ZhengHua LIU Kai LI XiaoLei LIU Rui WANG JingXiu WANG Shui | 2020 | Science China(Technological Sciences)2020，63，9： | 4 |
| 20 | Laser pattern-induced unidirectional lubricant flow for lubrication track replenishment显示文摘Effective oil replenishment to the lubrication track of a running bearing is crucial to its sustainable operation.Reliable practical solutions are rare despite numerous theoretical studies were conducted in the last few decades.This paper proposes the use of surface effect,wettability gradient,to achieve the goal.This method is simple and can be nicely implemented using femtosecond laser ablation.A periodic comb-tooth-shaped pattern with anisotropic wetting capability is devised and its effect on the anisotropic spreading behaviour of an oil droplet is studied.Results show that the comb-tooth-shaped pattern enables the rearrangement of oil distribution,thereby escalating oil replenishment to the lubrication track.The effect is due to the unbalanced interfacial force created by the surface pattern.The influence of the shape and the pitch of teeth,which are the two governing factors,on oil transport is also reported.The effects of the newly devised surface pattern on lubrication are experimentally evaluated under the conditions of limited lubricant supply.These results are promising,demonstrating the reduction in bearing friction and the increase in lubricating film thickness. | Chenglong LIU Feng GUO Patrick WONG Xinming LI | 2022 | Friction2022，10，8： | 4 |
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