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| 1 | Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer显示文摘渗入肿瘤的 Tregs 的起源,肿瘤免疫力的抑制的批评调停人,是不清楚的。这里,,我们证明在人的乳癌的渗入肿瘤的天真的 CD4 + T 房间和 Tregs 有重叠 TCR 全部剧目几乎别与传播 Tregs 重叠,建议 intratumoral Tregs 主要在 situ 而非从招募的 Tregs 从天真的 T 房间发展。而且,许多天真的 CD4 + T 房间和 Tregs 密切被相关,两个显示的穷人为乳癌病人的预后。天真的 CD4 + T 房间与许多生产 CCL18 巨噬细胞成比例遵守肿瘤片。而且,采纳地转移的人的天真的 CD4 + T 房间以一种 CCL18 依赖的方式渗入人的乳癌 orthotopic 异种皮移植。在在人性化的鼠标的人的乳癌异种皮移植,由将 PITPNM3 的表达式击倒堵住天真的 CD4 + T 房间的招募进肿瘤, CCL18 受体,显著地减少 intratumoral Tregs 并且禁止肿瘤前进。这些调查结果建议那个乳房渗入肿瘤的 Tregs 从在 situ 区分进 Tregs 的传播天真的 CD4 + T 房间的趋化性产生。由防碍 CCL18 的 PITPNM3 识别禁止天真的 CD4 + T 房间招募进肿瘤可以是为 anticancer 免疫疗法的吸引人的策略。 | Shicheng Su Jianyou Liao Jiang Liu Di Huang Chonghua He Fei Chen LinBing Yang Wei Wu Jianing Chen Ling Lin Yunjie Zeng Nengtai Ouyang Xiuying Cui Herui Yao Fengxi Su Jian-dong Huang Judy Lieberman Qiang Liu Erwei Song | 2017 | Cell Research2017，27，4： | 19 |
| 2 | Antioxidant properties of several commercial mushrooms显示文摘 | Yang J H Linb H C Maub J L | 2002 | Food Chemistry2002，77，： | 1 |
| 3 | Antioxidant properties of several commercial mushrooms显示文摘 | Yang J H Linb H C Maub J L | 2002 | Food Chemistry2002，，77： | 1 |
| 4 | Thermal analysis of soybean oil based polyols 显示文摘 | LinB L Yang H Dai Q | 2009 | Journal of Thermal Analysis and Calorimetry2009，3，： | 1 |
| 5 | Thermal analysis of soybeanoil based polyols 显示文摘 | LINB L YANG H DAI Q | 2009 | Journal of Thermal Analysis and Calorimetry2009，3，： | 1 |
| 6 | A preliminary research on wireless cantilever beam vibration sensor in bridge health monitoring显示文摘根据特定的桥环境,最佳的设计由使用理论计算和模拟的结果的压电的伸臂横梁结构,由实验验证压电的伸臂横梁和数据的生产能力的自然频率,因此形成了压电的伸臂横梁的设计方法的一个完全的集合。就颤动的自然频率和横梁身体的紧张而言,设计压电的伸臂横梁结构的一种新类型。纸分析传感器数据获得和传播的原则,设计一个硬件集成系统包括变换模块,微控制器模块和无线传播模块,读的测试本地人和为联合的无线传播伸臂横梁和数据收集卡片组织的信号,收音机的试验性的确认压电的颤动伸臂颤动反应是未经触动的,横梁由颤动生产了信号,获得卡片变换并且无线播送最后,纸设计了颤动伸臂横梁的一种新无线传感器,对基于事情的因特网监视的小桥健康合适。 | Xinlong TONG Shanglin SONG Linbing WANG Hailu YANG | 2018 | Frontiers of Structural and Civil Engineering2018，12，2： | 1 |
| 7 | Correction To:Intranasal booster using an Omicron vaccine confers broad mucosal and systemic immunity against SARSCoV-2 variants显示文摘Correction to:Signal Transduction and Targeted Therapy http://gffzzd3cc09b8251d45dfsbfxpxncu6ppo6pnn.ffgz.tsg.suse.edu.cn/10.1038/s41392-023-01423-6,published online 17 April 2023 After online publication of the article^(1),the authors noticed two inadvertent mistakes occurred in References that needs to be corrected.The correct text is provided as follows. | Qian Wang Chenchen Yang Li Yin Jing Sun Wei Wang Hengchun Li Zhengyuan Zhang Si Chen Bo Liu Zijian Liu Linjing Shi Xiaolin Liu Suhua Guan Chunhua Wang Linbing Qu Ying Feng Xuefeng Niu Liqiang Feng Jincun Zhao Pingchao Li Ling Chen Nanshan Zhong | 2023 | Signal Transduction and Targeted Therapy2023，8，6： | 1 |
| 8 | Antioxidant properties of several commercial mushrooms显示文摘 | YANG J H LINB H C M aub J L | 2002 | Food Chemistry2002，77，： | 1 |
| 9 | Characteristics and opti- cal properties of iron ion-doped titanium oxide thin films prepared by a sol-gel spin coating 显示文摘 | Wanga Yl C Linb H J Yang T S | 2009 | J Alloys Compd2009，473，： | 1 |
| 10 | Structural optimization design of semi-rigid base asphalt pavement using modulus matching criterion and multi-indicator range analysis显示文摘Damage to semi-rigid base asphalt pavement is related to improper matching of the pavement structure moduli.This study mainly focused on the modulus matching of structural layers and the development of a pavement structure optimization method.First,the modulus loss of existing pavement structures was analysed,and a three-dimensional finite element model was established based on the existing pavement.Second,the influence of the modulus of each structural layer on the mechanical response indicators and fatigue life was analysed.Based on the results,a pavement structure design method using the smoothness of the stress-strain curve as the modulus matching criterion of the structural layers was proposed.And it was found that a strain convex point was present and that the stress mutation between the structural layers was significant when the modulus matching of the pavement structure was reasonable.Further,the evaluation indicators were divided into two groups,namely,mechanical indicators and fatigue life indicators.And it was proposed an optimized pavement structure design method based on modulus matching and multi-indicator range analysis.Finally,the optimal modulus combination of pavement structure was determined by this method.The research systematically studied the influence of the modulus of each structural layer on the mechanical response and fatigue life of the pavement,and proposed the concept and specific executive criteria of modulus matching for the first time.Meanwhile,it also provided an effective optimization method for pavement structure design. | Zhihao Yang Linbing Wang Dongwei Cao Yinghao Miao Hailu Yang | 2024 | Journal of Traffic and Transportation Engineering(English Edition)2024，11，1： | 0 |
| 11 | Intranasal booster using an Omicron vaccine confers broad mucosal and systemic immunity against SARS-CoV-2 variants显示文摘The highly contagious SARS-CoV-2 Omicron subvariants severely attenuated the effectiveness of currently licensed SARS-CoV-2 vaccines based on ancestral strains administered via intramuscular injection.In this study,we generated a recombinant,replication-incompetent human adenovirus type 5,Ad5-S-Omicron,that expresses Omicron BA.1 spike.Intranasal,but not intramuscular vaccination,elicited spike-specific respiratory mucosal IgA and residential T cell immune responses,in addition to systemic neutralizing antibodies and T cell immune responses against most Omicron subvariants.We tested intranasal Ad5-S-Omicron as a heterologous booster in mice that previously received intramuscular injection of inactivated ancestral vaccine.In addition to inducing serum broadly neutralizing antibodies,there was a significant induction of respiratory mucosal IgA and neutralizing activities against Omicron subvariants BA.1,BA.2,BA.5,BA.2.75,BF.7 as well as pre-Omicron strains Wildtype,Beta,and Delta.Serum and mucosal neutralizing activities against recently emerged XBB,BQ.1,and BQ.1.1 could also be detected but were much lower.Nasal lavage fluids from intranasal vaccination contained multimeric IgA that can bind to at least 10 spike proteins,including Omicron subvariants and pre-Omicron strains,and possessed broadly neutralizing activities.Intranasal vaccination using Ad5-S-Omicron or instillation of intranasal vaccinee’s nasal lavage fluids in mouse nostrils protected mice against Omicron challenge.Taken together,intranasal Ad5-S-Omicron booster on the basis of ancestral vaccines can establish effective mucosal and systemic immunity against Omicron subvariants and multiple SARS-CoV-2 variants.This candidate vaccine warrants further development as a safe,effective,and user-friendly infection and transmission-blocking vaccine. | Qian Wang Chenchen Yang Li Yin Jing Sun Wei Wang Hengchun Li Zhengyuan Zhang Si Chen Bo Liu Zijian Liu Linjing Shi Xiaolin Liu Suhua Guan Chunhua Wang Linbing Qu Ying Feng Xuefeng Niu Liqiang Feng Jincun Zhao Pingchao Li Ling Chen Nanshan Zhong | 2023 | Signal Transduction and Targeted Therapy2023，8，5： | 0 |
| 12 | Anion-cation dual doping: An effective electronic modulation strategy of Ni2P for high-performance oxygen evolution显示文摘Developing of high-performance and low-cost electrocatalysts is of great significance to reduce the overpotential and accelerated the reaction rate of oxygen evolution in water splitting and related energy conversion applications.Herein,Fe,O-dual doped Ni2P(Fe,O-Ni2P)nanoarray is successfully synthesized on carbon cloth demonstrating enhanced electrocatalytic activity and stability for oxygen evolution reaction(OER)under alkaline media.The as-synthesized Fe,O-Ni2P nanoarray exhibits obviously improved OER performance with a low overpotential of 210 mV at 10 mA cm^-2 current density and a Tafel slope of48 mV dec^-1,as well as long-term durability.The strong coupling interaction induced changes in electronic structure lead to relatively higher oxidation state and stronger oxidation ability of the Fe,O-Ni2P nanoarray,together with the high electrochemical surface area and good conductivity contribute to the superior OER performance.This work highlights the anion-cation dual doping strategy may be an effective method for fabrication of catalysts relating to energy conversion applications. | Bo Xu Xiaodong Yang Qiang Fang Linbing Du Yan Fu Yiqiang Sun Qisheng Liu Qingquan Lin Cuncheng Li | 2020 | Journal of Energy Chemistry2020，29，9： | 0 |
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