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| 1 | SEUSS and PIF4 Coordinately Regulate Light and Temperature Signaling Pathways to Control Plant Growth显示文摘 | Junling Huai Xinyu Zhang dialong Li Tingting Ma Ping Zha Yanjun Jing Rongcheng Lin | 2018 | Molecular Plant2018，11，7： | 15 |
| 2 | The SWi2/SNF2 Chromatin-Remodeling ATPase BRAHMA Regulates Chlorophyll Biosynthesis in Arabidopsis显示文摘叶绿素生合成在植物为叶绿体开发和光合作用是批评的。尽管在叶绿素 biosynthetic 小径的反应大部分被知道了,很少对这条小径的规章的机制被知道。在这研究,我们发现象梵天(BRM ) 的 RNA 干扰转基因的幼苗一样的黑暗成年的猛烈、击倒的异种,它编码 SWI2/SNF2 改变染色质的 ATPase,有的更高的 greening 率,积累的更少 protochlorophyllide,和生产更少比 Arabidopsis,野类型的植物在轻暴露之上做了的反应的氧种类。NADPH:protochlorophyllide oxidoreductase A (PORA ) 的表示, PORB,和 PORC,在叶绿素生合成催化关键步,在 brm 异种被增加。我们发现那 BRM 身体上与 bHLH 抄写因素交往 PHYTOCHROME 因素 1 交往了(PIF1 ) 通过它的 N 终端领域。而且,我们证明 BRM 直接被招募到 PORC,然而并非 PORA 和 PORB 的 cis 规章的区域,至少,部分,以一种 PIF1 依赖的方式和 histone H3 离氨酸的水平,在 PORC loci 的 4 tri-methylation (H3K4me3 ) 在 brm 异种被增加。一起拿,我们的数据显示改变染色质的酶 BRM 通过与 PIF1 交往调制 PORC 表示,提供植物在转变期间由调整叶绿素生合成从的新奇规章的机制对自造营养物质的生长不是自养。 | Dong Zhang Yuhong Li Xinyu Zhang Ping Zha Rongcheng Lin | 2017 | Molecular Plant2017，10，1： | 10 |
| 3 | Large-scale real-world radio signal recognition with deep learning显示文摘In the past ten years, many high-quality datasets have been released to support the rapid development of deep learning in the fields of computer vision, voice, and natural language processing. Nowadays, deep learning has become a key research component of the Sixth-Generation wireless systems(6G) with numerous regulatory and defense applications. In order to facilitate the application of deep learning in radio signal recognition, in this work, a large-scale real-world radio signal dataset is created based on a special aeronautical monitoring system-Automatic Dependent Surveillance-Broadcast(ADS-B). This paper makes two main contributions. First, an automatic data collection and labeling system is designed to capture over-the-air ADS-B signals in the open and real-world scenario without human participation. Through data cleaning and sorting, a high-quality dataset of ADS-B signals is created for radio signal recognition. Second, we conduct an in-depth study on the performance of deep learning models using the new dataset, as well as comparison with a recognition benchmark using machine learning and deep learning methods.Finally, we conclude this paper with a discussion of open problems in this area. | Ya TU Yun LIN Haoran ZHA Ju ZHANG Yu WANG Guan GUI Shiwen MAO | 2022 | Chinese Journal of Aeronautics2022，35，9： | 9 |
| 4 | VX-765 reduces neuroinflammation after spinal cord injury in mice显示文摘Inflammation is a major cause of neuronal injury after spinal cord injury. We hypothesized that inhibiting caspase-1 activation may reduce neuroinflammation after spinal cord injury, thus producing a protective effect in the injured spinal cord. A mouse model of T9 contusive spinal cord injury was established using an Infinite Horizon Impactor, and VX-765, a selective inhibitor of caspase-1, was administered for 7 successive days after spinal cord injury. The results showed that:(1) VX-765 inhibited spinal cord injury-induced caspase-1 activation and interleukin-1β and interleukin-18 secretion.(2) After spinal cord injury, an increase in M1 cells mainly came from local microglia rather than infiltrating macrophages.(3) Pro-inflammatory Th1 Th17 cells were predominant in the Th subsets. VX-765 suppressed total macrophage infiltration, M1 macrophages/microglia, Th1 and Th1 Th17 subset differentiation, and cytotoxic T cells activation;increased M2 microglia;and promoted Th2 and Treg differentiation.(4) VX-765 reduced the fibrotic area, promoted white matter myelination, alleviated motor neuron injury, and improved functional recovery. These findings suggest that VX-765 can reduce neuroinflammation and improve nerve function recovery after spinal cord injury by inhibiting caspase-1/interleukin-1β/interleukin-18. This may be a potential strategy for treating spinal cord injury. This study was approved by the Animal Care Ethics Committee of Bengbu Medical College(approval No. 2017-037) on February 23, 2017. | Jing Chen Yu-Qing Chen Yu-Jiao Shi Shu-Qin Ding Lin Shen Rui Wang Qi-Yi Wang Cheng Zha Hai Ding Jian-Guo Hu He-Zuo Lü | 2021 | Neural Regeneration Research2021，16，9： | 8 |
| 5 | Key determinants of misdiagnosis of tracheobronchial tuberculosis among senile patients in contemporary clinical practice:A retrospective analysis显示文摘BACKGROUND Tracheobronchial tuberculosis(TBTB)is a common subtype of pulmonary tuberculosis.Concomitant diseases often obscure the diagnosis of senile TBTB.AIM To characterize senile patients with TBTB and to identify the potential causes of misdiagnosis.METHODS One hundred twenty patients with senile TBTB who were admitted to the Anhui Chest hospital between May 2017 and May 2019 were retrospectively analyzed.Patients were classified as diagnosed group(n=58)and misdiagnosed group(n=62).Clinical manifestations,laboratory results,radiographic data,and endoscopic findings were compared between the two groups.RESULTS Patients in the misdiagnosed group were most commonly diagnosed as pulmonary tuberculosis(non-TBTB,29/62,46.8%),general pneumonia(9/62,14.5%),chronic obstructive pulmonary disease(8/62,12.9%),and tracheobronchial carcinoma(7/62,11.3%).The time elapsed between disease onset and confirmation of diagnosis was significantly longer in the misdiagnosed group[median(first quartile,third quartile):6.32(4.94,16.02)mo vs 3.73(2.37,8.52)mo].The misdiagnosed group had lower proportion of patients who underwent bronchoscopy[33.87%(21/62)vs 87.93%(51/58)],chest computed tomography(CT)scan[69.35%(43/62)vs 98.28%(57/58)],and those who showed CT signs of tuberculosis[27.91%(12/62)vs 50%(29/58)]as compared to that in the diagnosed group(P<0.05).There were no significant between-group differences with respect to age,gender,occupation,clinical manifestations,or prevalence of comorbid chronic diseases(P>0.05).CONCLUSION Insufficient or inaccurate radiographic or bronchoscopic assessment was the predominant cause of delayed diagnosis of TBTB.Increased implementation and better interpretation of CT scan and early implementation of bronchoscopy can help reduce misdiagnosis of senile TBTB. | Fei Tang Lian-Jun Lin Shu-Liang Guo Wei Ye Xian-Kui Zha Yu Cheng Ying-Feng Wu Yue-Ming Wang Xiao-Mei Lyu Xiao-Yun Fan Li-Ping Lyu | 2021 | World Journal of Clinical Cases2021，9，25： | 6 |
| 6 | A Model for Estimating Total Forest Coverage with Ground-Based Digital Photography显示文摘Vegetation fractional coverage (VFC) is one of the key indicators of vegetation distribution. In the work a measurement-based model was developed to derive total forest VFC (TG) as well as the VFC of trees (T) and shrub-grasses (G) separately in a subtropical forest area in Nanjing, China. Both upward and downward photographs were taken with a digital camera in 72 quadrats (10 m × 10 m each). Fifteen models were established and validated. Models jointly using both T and G performed better than those using the T and G separately. The best model, TG = T + G- 1.134 × T × G- 0.025 (R2 = 0.9115, P < 0.01, root mean squared error = 0.0789), is recommended for application. This model provides a good way to obtain total forest VFC values through taking tree and shrub-grass photos on ground below tree canopy rather than above tree canopy. | GU Zhu-Jun ZENG Zhi-Yuan SHI Xue-Zheng LI Lin D. C. WEINDORF ZHA Yong YU Dong-Sheng LIU YongoMei | 2010 | Pedosphere2010，20，3： | 5 |
| 7 | Effect of glycine addition on the in-vitro corrosion behavior of AZ31 magnesium alloy in Hank’s solution显示文摘This study reports on the effect of the addition of Glycine to Hank’s solution on the in-vitro corrosion behavior of AZ31 magnesium(Mg)alloy at 37℃and a pH of 7.4 studied by using potentiodynamic polarization(PDP),hydrogen collecting techniques and electrochemical impedance spectroscopy(EIS)in combination with surface characterization techniques such as optical microscopy(OM),scanning electron microscopy(SEM),energy dispersive spectroscopy(EDS),X-ray diffraction(XRD)and X-ray photoelectron spectroscopy analysis(XPS).The results reveal that adsorption of glycine initially subdues the dissolution of AZ31 Mg alloy while in long run it enhances the dissolution of the alloy due to the commencement of the chelation effect of glycine with Ca^(2+) released from hydroxyapatite.The chelation of glycine with Ca^(2+) induces the formation of cracks in the surface film which further promotes the dissolution of AZ31 Mg alloy thereby forming a porous corrosion products layer on the surface of the alloy.As a result,both the continuous dissolution of AZ31 magnesium alloy and the hydrogen evolution rate(HER)are enhanced with increasing the immersion time in Hank’s solution. | Durga Bhakta Pokharel Liping Wu Junhua Dong Amar Prasad Yadav Dhruba Babu Subedi Madhusudan Dhakal Lin Zha Xin Mu Aniefiok Joseph Umoh Wei Ke | 2021 | Journal of Materials Science & Technology2021，，22： | 4 |
| 8 | Efficient CO_2 capture on low-cost silica gel modified by polyethyleneimine显示文摘In this work,a series of polyethyleneimine(PEI) functionalized commercial silica gel were prepared by wet impregnation method and used as CO 2 sorbent.The as-prepared sorbents were characterized by N 2 adsorption,FT-IR and SEM techniques.CO 2 capture was tested in a fixed bed reactor using a simulated flue gas containing 15.1% CO 2 in a temperature range of 25-100 C.The effects of sorption temperature and amine content on CO 2 uptake of the adsorbents were investigated.The silica gel with a 30 wt% PEI loading manifested the largest CO 2 uptake of 93.4 mg CO 2 /g adsorbent(equal to 311.3 mg CO 2 /g PEI) among the tested sorbents under the conditions of 15.1%(v/v) CO 2 in N 2 at 75 C and atmospheric pressure.Moreover,it was rather low-cost.In addition,the PEI-impregnated silica gel exhibited stable adsorption-desorption behavior during 5 consecutive test cycles.These results suggest that the PEI-impregnated silica gel is a promising and cost-effective sorbent for CO 2 capture from flue gas and other stationary sources with low CO 2 concentration. | Ke Wang Hongyan Shang Lin Li Xinlong Yan Zifeng Yan Chenguang Liu Qingfang Zha | 2012 | Journal of Natural Gas Chemistry2012，21，3： | 4 |
| 9 | Nested-PCR assay for detection of Schistosoma japonicum infection in domestic animals显示文摘Background:Schistosomiasis japonica is a common zoonosis.Domestic animals are the primary source of infection and play an important role in disease transmission.The prevalence and infectivity of this disease in domestic animals in China have significantly decreased and,for this reason,diagnostics with a higher sensitivity have become increasingly necessary.It was reported that polymerase chain reaction(PCR)-based methods could be used to detect schistosome infection in humans and animals and presented a high sensitivity and specificity.The present study aimed to develop a PCR-based method for detection of Schistosoma japonicum infection in domestic animals.Methods:A specific nested-PCR assay was developed to detect S.japonicum infection in domestic animals via amplification of a 231-bp DNA fragment of retrotransposon SjR2.The developed assay was first used in sera and dry blood filter paper(DBFP)from goats and buffaloes at different time points of infection.Then,78 DBFPs from 39 artificially-infected bovines at 14 and 28 days post-infection and 42 DBFPs from schistosome-negative bovines from the city of Huangshan in the Anhui province were used to evaluate the diagnostic validity.Furthermore,this assay was used to detect S.japonicum infection in domestic animals in Dongzhi and Wangjiang counties.Results:The expected PCR product was detected in eggs and adult worms of S.japonicum and blood samples from S.japonicum-infected goats and water buffaloes,but not from Fasciola and Haemonchus contortus worms.The nested-PCR assay could detect the target S.japonicum DNA in DBFPs from goats and buffaloes after day 3 post-infection.The sensitivity in buffaloes at 14 and 28 days post-infection was 92.30%(36/39)and 100%(39/39),respectively.The specificity was 97.60%(41/42).The positivity rates in Dongzhi and Wangjiang counties were 6.00%and 8.00%in bovines and 22.00%and 16.67%in goats,respectively.The positivity rates in goats in both counties were higher than those in bovines with a significant difference in Dongzhi County but not in Wangjiang County(P<0.05 and P=0.23,respectively).Conclusions:Our results suggest that the developed nested-PCR assay may be used for the diagnosis of S.japonicum infection in domestic animals,and the control of S.japonicum infection in goats should be paid more attention. | Xin Zhang Chuan-Chuan He Jin-Ming Liu Hao Li Ke Lu Zhi-Qiang Fu Chuan-Gang Zhu Yi-Ping Liu Lai-Bao Tong De-bao Zhou Li Zha Yang Hong Ya-Mei Jin Jiao-Jiao Lin | 2017 | Infectious Diseases of Poverty2017，6，1： | 4 |
| 10 | The Evening Complex and the Chromatin-Remodeling Factor PICKLE Coordinately Control Seed Dormancy by Directly Repressing DOG1 in Arabidopsis显示文摘Primary seed dormancy is acquired during seed development and maturation,which is important for plant fitness and survival.DELAY OF GERMINATION1(DOG1)plays a critical role in inducing seed dormancy.DOG1 expression increases rapidly during seed development,but the precise mechanism underlying this process remains elusive.In this study,we showed that mutants with a loss or reduced function of the chromatin-remodeling factor PICKLE(PKL)exhibit increased seed dormancy.PKL associates with DOG1 chromatin and inhibits its transcription.We found that PKL physically interacts with LUX ARRHYTHMO(LUX),a member of the evening complex(EC)of the circadian clock.Furthermore,LUX directly binds to a specific coding sequence of DOG1,and DOG1 acts genetically downstream of PKL and LUX.Mutations in either LUX or EARLY FLOWERING3(ELF3)encoding another member of the EC led to increased DOG1 expression and enhanced seed dormancy.Surprisingly,these phenotypes were abolished when the parent plants were grown under continuous light.In addition,we observed that loss of function of either PKL or LUX decreased H3K27me3 levels at the DOG1 locus.Taken together,our study reveals a regulatory mechanism in which EC proteins coordinate with PKL to transmit circadian signals for directly regulating DOG1 expression and seed dormancy during seed development. | Ping Zha Shuangrong Liu Yang Li Tingting Ma Liwen Yang Yanjun Jing Rongcheng Lin | 2020 | Plant Communications2020，1，2： | 3 |
| 11 | An Evolutionary Economic Geography Perspective on Types of Operation Development in West Lake, China显示文摘The types of operation play a key role in facilitating tourism consumption and economic development in a tourism destination. By adopting evolutionary economic geography theory, the paper analyzes the types of operation in West Lake Scenic Area from 1978 to 2013. First, an evolution process consisting of four stages is underpinned, and they are: the new establishment stage, the preliminary development stage, the speedup development stage, and the stabilized maturity stage. Specifically, the distinct characteristics associated with operation types are compared and evaluated at different stages throughout the process. The evolution trees are introduced to scrutinize types of operation development. The results of evolution trees demonstrate the substantial increase in both numbers and types. Second, by applying GIS spatial analysis, the paper also analyzes the spatial evolution characteristics on the types of operation, and the results unveil the co-existence of centripetal and centrifugal forces: the processes of spatial agglomeration and spatial dispersion. More specifically, we recognize the spatial process includes the emergence of node and concentration(1978–1995), the sparse distribution and intensity reduction(1996–2002), the patchy distribution and spatial agglomeration intensification(2003–2008), the dispersed distribution and core area agglomeration(2009–2013). Lastly, path dependence on resource endowment, government and market innovation, knowledge learning and spillover can reasonably explain the types of operation evolution. In conclusion, the evolutionary economic geography theories provide new theoretical and empirical perspectives for tourism policy analysis. At the same time, our comprehensive evidences impart more comprehensive insights and offer useful managerial and policy implications. | YANG Xingzhu ZHA Yanyan LU Lin YANG Yang | 2017 | Chinese Geographical Science2017，27，3： | 3 |
| 12 | Two-dimensional multimetallic sulfide nanosheets with multi-active sites to enhance polysulfide redox reactions in liquid Li2S6-based lithium-polysulfide batteries显示文摘The lithium-sulfur battery has attracted enormous attention as being one of the most significant energy storage technologies due to its high energy density and cost-effectiveness.However,the 'shuttle effect' of polysulfide intermediates represents a formidable challenge towards its wide applications.Herein,we have designed and synthesized two-dimensional Cu,Zn and Sn-based multimetallic sulfide nanosheets to construct multi-active sites for the immobilization and entrapment of polysulfides with offering better performance in liquid Li2S6-based lithium-polysulfide batteries.Both experimental measurements and theoretical computations demonstrate that the interfacial multi-active sites of multimetallic sulfides not only accelerate the multi-chained redox reactions of highly diffusible polysulfides,but also strengthen affinities toward polysulfides.By adopting multimetallic sulfide nanosheets as the sulfur host,the liquid Li2 S6-based cell exhibits an impressive rate capability with 1200 mAh/g and retains 580 mAh/g at 0.5 mA/cm^(2) after 1000 cycles.With high sulfur mass loading conditions,the cell with 2.0 mg/cm^(2) sulfur loading delivers a cell capacity of 1068 mAh/g and maintains 480 mAh/g with 0.8 mA/cm^(2) and 500 cycles.This study provides new insights into the multifunctional material design with multi-active sites for elevated lithium-polysulfide batteries. | Chenyang Zha Donghai Wu Yuwei Zhao Jun Deng Jinghua Wu Rong Wu Meng Yang Lin Wang Houyang Chen | 2021 | Journal of Energy Chemistry2021，30，1： | 3 |
| 13 | Consolidated cluster systems for data centers in the cloud age: a survey and analysis显示文摘 | Jian LIN Li ZHA Zhiwei XU | 2013 | Frontiers of Computer Science2013，7，1： | 2 |
| 14 | Nonlinear Dimensionality Reduction by Local Orthogonality Preserving Alignment显示文摘我们在场一个新歧管的学习算法叫了保存排列(LOPA ) 的本地 Orthogonality。我们的算法被试图用仿射的转变排列多重本地邻居进一个全球坐标系统的本地正切空间排列(LTSA ) 方法启发。然而, LTSA 经常没能保存象距离和角度那样的原来的几何数量。尽管为保存 orthogonality 的一个反复的排列过程被 LTSA 的作者建议,既不相应初始化也不实验被给。普罗克拉斯提斯 Subspaces 排列(PSA ) 实现由与退火模仿独立估计每旋转转变保存想法的 orthogonality。然而,在 PSA 的优化是复杂、多重的分开的本地旋转可以生产全球性倾向於矛盾的结果。探讨这些困难,我们首先使用 LTSA 的伪逆诡计与统一全球坐标代表每本地直角的转变。第二, orthogonality 限制被放松是半明确的编程(SDP ) 的一个例子。最后一个二拍子的圆舞反复的过程被采用进一步在直角的限制减少错误。广泛的实验证明 LOPA 能忠实地保存原来的数据集的距离,角度,内部产品,和邻居。在比较,当 LOPA 的运行时刻比 PSA, MVU 和 MVE 的显著地快时, LOPA 的嵌入的表演比 PSA 的好、比得上象 MVU 和 MVE 一样的最先进的算法的。 | Tong Lin Yao Liu Bo Wang Li-Wei Wang Hong-Bin Zha | 2016 | Journal of Computer Science & Technology2016，31，3： | 2 |
| 15 | Estimation of the age of human semen stains by attenuated total reflection Fourier transform infrared spectroscopy:a preliminary study显示文摘Semen stain is one of the most important biological evidence at sexual crime scenes.Age estimation of human semen stains plays an important role in forensic work,and it is rarely studied due to lack of well-established methods.In this study,the technique called attenuated total reflection Fourier transform infrared spectroscopy(ATR-FTIR)coupled with advanced chemometric methods was employed to determine the age of semen stains on three different substrates:glass slides,tissues and fabric made of regenerated cellulose fibres up to 6 d.Partial least squares regression(PLSR)was used in conjunction with spectral analysis for age estimation,and the results generated high R2 values(cross-validation:0.81,external validation:0.74)but a narrow margin of error for root mean square error(RMSE)(RMSE of cross-validation:0.77 d,RMSE of prediction:1.02 d).Additionally,our results indicated the robustness of PLSR model was not weaken by the influence of different substrates in this study.Our results indicate that ATR-FTIR,combined with chemometric methods,shows great potential as a convenient and efficient tool for age estimation of semen stains.Moreover,the method could be applied to routine forensic investigations in the future. | Shuai Zha Xin Wei Ruoxi Fang Qi Wang Hancheng Lin Kai Zhang Haohui Zhang Ruina Liu Zhouru Li Ping Huang Zhenyuan Wang | 2020 | Forensic Sciences Research2020，5，2： | 2 |
| 16 | Recent Advances in Two-Dimensional Magnets:Physics and Devices towards Spintronic Applications显示文摘The emergence of low-dimensional nanomaterials has brought revolutionized development of magnetism,as the size effect can significantly influence the spin arrangement.Since the first demonstration of truly two-dimensional magnetic materials(2DMMs)in 2017,a wide variety of magnetic phases and associated properties have been exhibited in these 2DMMs,which offer a new opportunity to manipulate the spin-based devices efficiently in the future.Herein,we focus on the recent progress of 2DMMs and heterostructures in the aspects of their structural characteristics,physical properties,and spintronic applications.Firstly,the microscopy characterization of the spatial arrangement of spins in 2D lattices is reviewed.Afterwards,the optical probes in the light-matter-spin interactions at the 2D scale are discussed.Then,particularly,we systematically summarize the recent work on the electronic and spintronic devices of 2DMMs.In the section of electronic properties,we raise several exciting phenomena in 2DMMs,i.e.,long-distance magnon transport,field-effect transistors,varying magnetoresistance behavior,and(quantum)anomalous Hall effect.In the section of spintronic applications,we highlight spintronic devices based on 2DMMs,e.g.,spin valves,spin-orbit torque,spin field-effect transistors,spin tunneling field-effect transistors,and spin-filter magnetic tunnel junctions.At last,we also provide our perspectives on the current challenges and future expectations in this field,which may be a helpful guide for theorists and experimentalists who are exploring the optical,electronic,and spintronic properties of 2DMMs. | Vertikasari PNingrum Bowen Liu Wei Wang Yao Yin Yi Cao Chenyang Zha Hongguang Xie Xiaohong Jiang Yan Sun Sichen Qin Xiaolong Chen Tianshi Qin Chao Zhu Lin Wang Wei Huang | 2020 | Research2020，，1： | 2 |
| 17 | Development and high-gradient test of a two-half accelerator structure显示文摘This paper reports on the design,fabrication,RF measurement,and high-power test of a prototype accelerator—such as 11.424 GHz with 12 cells—and a traveling wave of two halves.It was found that the unloaded gradient reached 103 MV/m during the high-power test and the measured breakdown rate,after 3.17×10^(7) pulses,was 1.62×10^(-4)/pulse/m at 94 MV/m and a 90 ns pulse length.We thus concluded that the high-gradient two-half linear accelerator is cost-effective,especially in high-frequency RF linear acceleration.Finally,we suggest that silverbased alloy brazing can further reduce costs. | Mao-Mao Peng Jia-Ru Shi Hao Zha Xian-Cai Lin Ze-Ning Liu Yu-Liang Jiang Jian Gao Liu-Yuan Zhou Fo-Cheng Liu Xiang-Cong Meng Huai-Bi Chen | 2021 | Nuclear Science and Techniques2021，32，6： | 1 |
| 18 | Collagen1α1 promoter drives the expression of Cre recombinase in osteoblasts of transgenic mice显示文摘Osteoblasts participate in bone formation, bone mineralization, osteoclast differentiation and many pathological processes. To study the function of genes in osteoblasts using Cre-LoxP system, we generated a mouse line expressing the Cre recombinase under the control of the rat Collagen1α1 (Col1α1) promoter (Col1α1-Cre). Two founders were identified by genomic PCR from 16 offsprings, and the integration efficiency is 12.5%. In order to determine the tissue distribution and the activity of Cre recombinase in the transgenic mice, the Col1α1-Cre transgenic mice were bred with the ROSA26 reporter strain and a mouse strain that carries Smad4 conditional alleles (Smad4Co/Co). Multiple tissue PCR of Col1α1-Cre;Smad4Co/+ mice revealed the restricted Cre activity in bone tissues containing osteoblasts and tendon. LacZ staining in the Col1α1-Cre;ROSA26 double transgenic mice revealed that the Cre recombinase began to express in the osteoblasts of calvaria at E14.5. Cre activity was observed in the osteoblasts and osteocytes of P10 double transgenic mice. All these data indicated that the Col1α1-Cre transgenic mice could serve as a valuable tool for osteoblast lineage analysis and conditional gene knockout in osteoblasts. | Lagabaiyila Zha Ning Hou Jian Wang Guan Yang Yuanrong Gao Lin Chen Xiao Yang | 2008 | Journal of Genetics and Genomics2008，35，9： | 1 |
| 19 | Riemannian manifold learning显示文摘 | LIN Tong ZHA Hongbin | 2008 | IEEE Transactions on Pattern Analysis and Machine Intelligence2008，30，5： | 1 |
| 20 | Development of a seven-cell S-band standing-wave RF-deflecting cavity for Tsinghua Thomson scattering X-ray source显示文摘A 2856-MHz,π-mode,seven-cell standingwave deflecting cavity was designed and fabricated for bunch length measurement in Tsinghua Thomson scattering X-ray source(TTX)facility.This cavity was installed in the TTX and provided a deflecting voltage of 4.2 MV with an input power of 2.5 MW.Bunch length diagnoses of electron beams with energies up to 39 MeV have been performed.In this article,the RF design of the cavity using HFSS,fabrication,and RF test processes are reviewed.High-power operation with accelerated beams and calibration of the deflecting voltage are also presented. | Xian-Cai Lin Hao Zha Jia-Ru Shi Liu-Yuan Zhou Shuang Liu Jian Gao Huai-Bi Chen | 2021 | Nuclear Science and Techniques2021，32，4： | 1 |
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