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| 1 | Field investigation on severely damaged aseismic buildings in 2014 Ludian earthquake显示文摘The 2014 magnitude 6.5 Ludian earthquake caused a death toll of 617, many landslides and tens of thousands of collapsed buildings. A field investigation to evaluate the damage to buildings was carried out immediately after the occurrence of the earthquake. Severely damaged aseismic buildings, which were basically observed in the downtown of Longtoushan Town, were carefully examined one by one with the aim to improve design codes. This paper summarizes the damage observed to the investigated aseismic buildings in both the structural and local levels. A common failure mode was observed that most of the aseismic buildings, such as RC frame structures and confined masonry structures, were similarly destroyed by severe damage or complete collapse of the first story. The related strong ground motion, which was recorded at the nearby station, had a short duration of less than 20 s but a very large PGA up to 1.0 g. The RC frames based on the new design codes still failed to achieve the design target for 'strong column, weak beam'. Typical local failure details, which were related to the interaction between RC columns and infill walls and between constructional columns and masonry walls, are summarized with preliminary analyses. | Lin Xuchuan Zhang Haoyu Chen Hongfu Chen Hao Lin Junqi | 2015 | Earthquake Engineering and Engineering Vibration2015，14，1： | 12 |
| 2 | Expert consensus on dental caries management显示文摘Dental Caries is a kind of chronic oral disease that greatly threaten human being’s health.Though dentists and researchers struggled for decades to combat this oral disease,the incidence and prevalence of dental caries remain quite high.Therefore,improving the disease management is a key issue for the whole population and life cycle management of dental caries.So clinical difficulty assessment system of caries prevention and management is established based on dental caries diagnosis and classification.Dentists should perform oral examination and establish dental records at each visit.When treatment plan is made on the base of caries risk assessment and carious lesion activity,we need to work out patient-centered and personalized treatment planning to regain oral microecological balance,to control caries progression and to restore the structure and function of the carious teeth.And the follow-up visits are made based on personalized caries management.This expert consensus mainly discusses caries risk assessment,caries treatment difficulty assessment and dental caries treatment plan,which are the most important parts of caries management in the whole life cycle. | Lei Cheng Lu Zhang Lin Yue Junqi Ling Mingwen Fan Deqin Yang Zhengwei Huang Yumei Niu Jianguo Liu Jin Zhao Yanhong Li Bin Guo Zhi Chen Xuedong Zhou | 2022 | International Journal of Oral Science2022，14，2： | 8 |
| 3 | Expert consensus on regenerative endodontic procedures显示文摘Regenerative endodontic procedures(REPs)is a biologic-based treatment modality for immature permanent teeth diagnosed with pulp necrosis.The ultimate objective of REPs is to regenerate the pulp-dentin complex,extend the tooth longevity and restore the normal function.Scientific evidence has demonstrated the efficacy of REPs in promotion of root development through case reports,case series,cohort studies,and randomized controlled studies.However,variations in clinical protocols for REPs exist due to the empirical nature of the original protocols and rapid advancements in the research field of regenerative endodontics.The heterogeneity in protocols may cause confusion among dental practitioners,thus guidelines and considerations of REPs should be explicated.This expert consensus mainly discusses the biological foundation,the available clinical protocols and current status of REPs in treating immature teeth with pulp necrosis,as well as the main complications of this treatment,aiming at refining the clinical management of REPs in accordance with the progress of basic researches and clinical studies,suggesting REPs may become a more consistently evidence-based option in dental treatment. | Xi Wei Maobin Yang Lin Yue Dingming Huang Xuedong Zhou Xiaoyan Wang Qi Zhang Lihong Qiu Zhengwei Huang Hanguo Wang Liuyan Meng Hong Li Wenxia Chen Xiaoying Zou Junqi Ling | 2022 | International Journal of Oral Science2022，14，4： | 5 |
| 4 | Acupuncture/electroacupuncture enhances antidepressant effect of Seroxat:the Symptom Checklist-90 scores显示文摘One hundred and five patients with primary unipolar depression were randomly divided into three groups: drug group(Seroxat administration), acupuncture group(Seroxat plus acupuncture), and electroacupuncture group(Seroxat plus acupuncture plus electroacupuncture). Patients' symptoms were evaluated using a psychometric questionnaire, the Symptom Checklist-90, before intervention and after 2, 4, 6 and 10 weeks of treatment. The individual factor scores and the total score from the Symptom Checklist-90 reduced in all three groups as treatment progressed. In the acupuncture and electroacupuncture groups, the total score and the factor scores for obsessive-compulsive symptoms, depression, and anxiety were significantly lower than those in the drug group. There was no significant difference in the factor scores or total scores between the acupuncture and electroacupuncture groups. Some factor scores in the electroacupuncture group, such as somatization, depression, hostility, and phobic anxiety, were increased at 10 weeks compared with the respective score immediately after the course of electroacupuncture at 6 weeks. Our findings indicate that administration of Seroxat alone or in combination with acupuncture/electroacupuncture can produce a significant effect in patients with primary unipolar depression. Furthermore, acupuncture/electroacupuncture has a rapid onset of therapeutic effect and produces a noticeable improvement in obsessive-compulsive, depressive and anxiety symptoms. | Junqi Chen Weirong Lin Shengxu Wang Chongqi Wang Ganlong Li Shanshan Qu Yong Huang Zhangjin Zhang Wei Xiao | 2014 | Neural Regeneration Research2014，9，2： | 4 |
| 5 | Improvement in quality of life in depressed patients following verum acupuncture or electroacupuncture plus paroxetine:A randomized controlled study of 157 cases显示文摘Depressed patients with scores of 17 or more on the 17 items of the Hamilton Depression Rating Scale were treated with the antidepressant drug paroxetine. They also underwent verum acupuncture or electroacupuncture at Baihui (GV20) and Yintang (GV29). The World Health Organization Quality of Life Scale Brief Version showed a significant increase in the total scores of patients who underwent verum acupuncture and electroacupuncture for 6 weeks compared with those who were given paroxetine only; significantly increased physical domain and social relationship scores in verum acupuncture patients compared with paroxetine only; and significantly elevated psychological domain scores with electroacupuncture compared with paroxetine only. These results indicate that both verum acupuncture and electroacupuncture can improve quality of life in depressed patients undergoing paroxetine treatment. | Shenghui Ma Shanshan Qu Yong Huang Junqi Chen Renyong Lin Chongqi Wang Ganlong Li Canghuan Zhao Shenchang Guo Zhangjin Zhang | 2012 | Neural Regeneration Research2012，7，27： | 3 |
| 6 | 96-Week Treatment of Tenofovir Amibufenamide and Tenofovir Disoproxil Fumarate in Chronic Hepatitis B Patients显示文摘Background and Aims:Tenofovir amibufenamide(TMF)is a novel phosphoramidated prodrug of tenofovir with nonin-ferior efficacy and better bone and renal safety to tenofovir disoproxil fumarate(TDF)in 48 weeks of treatment.Here,we update 96-week comparison results.Methods:Patients with chronic hepatitis B were assigned(2:1)to receive either 25 mg TMF or 300 mg TDF with matching placebo for 96 weeks.The virological suppression was defined as HBV DNA levels<20 IU/mL at week 96.Safety was evaluated thoroughly with focusing on bone,renal,and metabolic pa-rameters.Results:Virological suppression rates at week 96 were similar between TMF and TDF group in both HBeAg-positive and HBeAg-negative populations.Noninferior efficacy was maintained in the pooled population,while it was first achieved in patients with HBV DNA≥7 or 8 log10 IU/mL at baseline.Non-indexed estimated glomerular filtration rate for renal safety assessment was adopted,while a smaller decline of which was seen in the TMF group than in the TDF group(p=0.01).For bone mineral density,patients receiv-ing TMF displayed significantly lower reduction levels in the densities of spine,hip,and femur neck at week 96 than those receiving TDF.In addition,the lipid parameters were stable after week 48 in all groups while weight change still showed the opposite trend.Conclusions:TMF maintained similar efficacy at week 96 compared with TDF with continued superior bone and renal safety profiles(NCT03903796). | Zhihong Liu Qinglong Jin Yuexin Zhang Guozhong Gong Guicheng Wu Lvfeng Yao Xiaofeng Wen Zhiliang Gao Yan Huang Daokun Yang Enqiang Chen Qing Mao Shide Lin Jia Shang Huanyu Gong Lihua Zhong Huafa Yin Fengmei Wang Peng Hu Qiong Wu Chao Pan Wen Jia Chuan Li Chang’an Sun Junqi Niu Jinlin Hou TMF Study Group | 2023 | Journal of Clinical and Translational Hepatology2023，11，3： | 3 |
| 7 | Problems of durability and reinforcement measures for underground structures in China显示文摘In this paper,the bolt-and cable-supported structures mainly refer to anchored cables,anchored bolts,soil nails and other commonly used reinforcing and supporting structures in geotechnical engineering,as well as reinforced soil structures in permanent works.They are often used in combination,or formed into composite bolt-and cable-supported structures,with other traditional construction methods and relevant measures.Distinct characteristics of such structures are that they are most often invisible,exposed to more severe underground corrosive environments and with strict durability requirements.A number of serious durability problems of underground structures are discussed and major achievements and advances in China and abroad in terms of durability and reinforcement measures for underground structures are reviewed,followed by comprehensive analyses.Some suggestions for those problems are put forward. | Xianming Zeng Zhenyu Wang Junqi Fan Lin Zhao Dalu Lin Jian Zhao | 2011 | Journal of Rock Mechanics and Geotechnical Engineering2011，3，3： | 1 |
| 8 | Histological observation on unique phenotypes of malformation induced in Xenopus tropicalis larvae by tributyltin显示文摘Tributyltin(TBT),a biocide used in antifouling paints,has shown strong teratogenic effects on Xenopus tropicalis embryos at environmentally relevant concentrations.X.tropicalis embryos were exposed to 50,100 and 200 ng/L tributyltin chloride for 72 hr.The histological changes were further observed on abnormal eyes,enlarged trunks,enlarged proctodaeums and absence of fins induced by TBT.The lens and the retinal layers of abnormal eyes were slightly or barely differentiated,and that the pigment epithelium was neither continuous nor smooth.The abdomens were full of undifferentiated gut tissue with yolk-rich inclusions in the tadpoles with enlarged trunks.The proctodaeums formed a bump-like or columnar structure.The mass of yolk-rich cells occupied the lumen,blocked the opening and even turned inside out of the proctodaeum.Both the ventral and dorsal fins in trunks and tails became narrow or even disappeared totally.Our results suggest that great changes of histology took place corresponding to the unique phenotypes.The gut tissue was poorly differentiated,which led to the failed elongation of the guts and subsequently the enlarged trunks.The enlarged proctodaeums were due to the undifferentiation of inner layer,the expansion of outer epidermal part and the absence of fins around them.In brief,the histological observations provided insights into the reason of the unique external malformations in some degree. | Junqi Liu Qinzhen Cao Jing Yuan Xiaoli Zhang Lin Yu Huahong Shi | 2012 | Journal of Environmental Sciences2012，24，2： | 1 |
| 9 | Expert consensus on digital guided therapy for endodontic diseases显示文摘Digital guided therapy(DGT)has been advocated as a contemporary computer-aided technique for treating endodontic diseases in recent decades.The concept of DGT for endodontic diseases is categorized into static guided endodontics(SGE),necessitating a meticulously designed template,and dynamic guided endodontics(DGE),which utilizes an optical triangulation tracking system.Based on cone-beam computed tomography(CBCT)images superimposed with or without oral scan(OS)data,a virtual template is crafted through software and subsequently translated into a 3-dimensional(3D)printing for SGE,while the system guides the drilling path with a real-time navigation in DGE.DGT was reported to resolve a series of challenging endodontic cases,including teeth with pulp obliteration,teeth with anatomical abnormalities,teeth requiring retreatment,posterior teeth needing endodontic microsurgery,and tooth autotransplantation.Case reports and basic researches all demonstrate that DGT stand as a precise,time-saving,and minimally invasive approach in contrast to conventional freehand method.This expert consensus mainly introduces the case selection,general workflow,evaluation,and impact factor of DGT,which could provide an alternative working strategy in endodontic treatment. | Xi Wei Yu Du Xuedong Zhou Lin Yue Qing Yu Benxiang Hou Zhi Chen Jingping Liang Wenxia Chen Lihong Qiu Xiangya Huang Liuyan Meng Dingming Huang Xiaoyan Wang Yu Tian Zisheng Tang Qi Zhang Leiying Miao Jin Zhao Deqin Yang Jian Yang Junqi Ling | 2023 | International Journal of Oral Science2023，15，4： | 0 |
| 10 | LNCGM1082-mediated NLRC4 activation drives resistance to bacterial infection显示文摘The activation of NLRC4 is a major host response against intracellular bacteria infection.However,NLRC4 activation after a host senses diverse stimuli is difficult to understand.Here,we found that the IncRNA LNCGM1082 plays a critical role in the activation of NLRC4.LNCGM1082 in macrophages affects the maturation of interleukin(IL)-1βand pyroptotic cell death only after exposure to an NLRC4 ligand.Similar to NLRC4-/-mice,LNCGM1082-/-mice were highly sensitive to Salmonella Typhimurium(S.T)infection.LNCGM1082 deficiency in mouse or human macrophages inhibited IL-1βmaturation and pyroptosis.Mechanistically,LNCGM1082 induced the binding of PKCS with NLRC4 in both mice and humans.In contrast,NLRC4 did not bind PKCo in LNCGM1082-/-macrophages.The activity of the IncRNA LNCGM1082 induced by S.T may be mediated through TLR5 in the macrophages of both mice and humans.In summary,our data indicate that TLR5-mediated LNCGM1082 activity can promote the binding of PKC with NLRC4 to activate NLRC4 and induce resistance to bacterial infection. | Yunhuan Gao Yazheng Yang Jianmei Wei Jianmei Yue Ya Wang Qianjing Zhang Mengli Jin Rong Wang Xiaorong Yang Junqi Zhang Xinqi Liu Lin Liu Yuan Zhang Rongcun Yang | 2023 | Cellular & Molecular Immunology2023，20，5： | 0 |
| 11 | Expert consensus on difficulty assessment of endodontic therapy显示文摘Endodontic diseases are a kind of chronic infectious oral disease. Common endodontic treatment concepts are based on the removal of inflamed or necrotic pulp tissue and the replacement by gutta-percha. However, it is very essential for endodontic treatment to debride the root canal system and prevent the root canal system from bacterial reinfection after root canal therapy(RCT). Recent research, encompassing bacterial etiology and advanced imaging techniques, contributes to our understanding of the root canal system’s anatomy intricacies and the technique sensitivity of RCT. Success in RCT hinges on factors like patients, infection severity, root canal anatomy, and treatment techniques. Therefore, improving disease management is a key issue to combat endodontic diseases and cure periapical lesions. The clinical difficulty assessment system of RCT is established based on patient conditions, tooth conditions, root canal configuration, and root canal needing retreatment, and emphasizes pre-treatment risk assessment for optimal outcomes. The findings suggest that the presence of risk factors may correlate with the challenge of achieving the high standard required for RCT. These insights contribute not only to improve education but also aid practitioners in treatment planning and referral decision-making within the field of endodontics. | Dingming Huang Xiaoyan Wang Jingping Liang Junqi Ling Zhuan Bian Qing Yu Benxiang Hou Xinmei Chen Jiyao Li Ling Ye Lei Cheng Xin Xu Tao Hu Hongkun Wu Bin Guo Qin Su Zhi Chen Lihong Qiu Wenxia Chen Xi Wei Zhengwei Huang Jinhua Yu Zhengmei Lin Qi Zhang Deqin Yang Jin Zhao Shuang Pan Jian Yang Jiayuan Wu Yihuai Pan Xiaoli Xie Shuli Deng Xiaojing Huang Lan Zhang Lin Yue Xuedong Zhou | 2024 | International Journal of Oral Science2024，16，1： | 0 |
| 12 | Expert consensus on irrigation and intracanal medication in root canal therapy显示文摘Chemical cleaning and disinfection are crucial steps for eliminating infection in root canal treatment. However, irrigant selection or irrigation procedures are far from clear. The vapor lock effect in the apical region has yet to be solved, impeding irrigation efficacy and resulting in residual infections and compromised treatment outcomes. | Xiaoying Zou Xin Zheng Yuhong Liang Chengfei Zhang Bing Fan Jingping Liang Junqi Ling Zhuan Bian Qing Yu Benxiang Hou Zhi Chen Xi Wei Lihong Qiu Wenxia Chen Wenxi He Xin Xu Liuyan Meng Chen Zhang Liming Chen Shuli Deng Yayan Lei Xiaoli Xie Xiaoyan Wang Jinhua Yu Jin Zhao Song Shen Xuedong Zhou Lin Yue | 2024 | International Journal of Oral Science2024，16，1： | 0 |
| 13 | Phase Relationship in the Al-rich(Al+0.15at %V)-Mg-Zn System显示文摘Isothermal sections at room temperature and 450℃ for Al-rich(Al+0.15at%V)-Mg-Zn system have been determined bymeans of X-ray diffraction,microscopic observation and DTA methods.Comparing with Al-Mg-Zn system the α-phase regionof in isothermal sections room at temperature and 450℃ for the system with 0.15at%V is slightly narrowed and expandedrespectively.The solubilitiy limits of Zn and Mg in α-Al have been found to be 3.3at%(7.6wt%)and 5.5at%(5.0wt%)respectively at room temperature,and to be 6.0at%(13.4wt%)and 11.0at%(10.0wt%)at 450℃.The τ phase in this system is aternary intermetallic compound,which undergoes an allotropic transformation at about 427℃. | Tang, Junqi Li, Dexuan Lin, Weibo Zhuang, Yinghong | 1989 | Rare Metals1989，9，3： | 0 |
| 14 | 诱导多能性干细胞过程中染色质可及性动态变化规律显示文摘文章简介关于体细胞重编程中染色质结构重排的机制一直没有被清晰地研究过。本研究通过采用可在全基因组范围内研究开放染色质的ATAC(Assay for Transposase-Accessible Chromatin)技术。 | 李东伟 刘晶 杨雪洁 Chunhua Zhou Jing Guo Chuman Wu Yue Qin Lin Guo Jiangping He Shenyong Yu He Liu Xiaoshan Wang Fang Wu Junqi Kuang Andrew P.Hutchins 陈捷凯 裴端卿 | 2018 | 科学新闻2018，0，4： | 0 |
| 15 | Adaptive fault-tolerant control of high-speed maglev train suspension system with partial actuator failure: design and experiments显示文摘High-speed maglev trains will play an important role in the high-speed transportation system in the near future.However,under the conditions of strong magnetic fields and continuous operation,the actuators of the high-speed maglev train suspension system are prone to lose partial effectiveness,which makes the suspension control problem challenging.In addition,most existing fault-tolerant control(FTC)methods for suspension systems require linearization around the equilibrium points during the controller design or stability analysis.Therefore,from a practical perspective,this study presents a novel nonlinear FTC strategy with adaptive compensation for high-speed maglev train suspension systems.First,a nonlinear dynamic model of the suspension system based on join-structure is established and the actuator failures are described.Then,a nonlinear fault-tolerant suspension control law with an adaptive update law is designed to achieve stable suspension against partial actuator failure.The Lyapunov theory and extended Barbalat lemma are utilized to rigorously prove the closed-loop asymptotic stability even if there is partial actuator failure,without any approximation to the original nonlinear dynamics.Finally,hardware experimental results are included to demonstrate the effectiveness of the proposed approach. | Yougang SUN Fengxing LI Guobin LIN Junqi XU Zhenyu HE | 2023 | Journal of Zhejiang University-Science A(Applied Physics & Engineering)2023，24，3： | 0 |
| 16 | 30 Years of Climate Change before and after the Impoundment of the Three Gorges Reservoir显示文摘The Three Gorges Project, also known as the Yangtze River Three Gorges Water Control Project, is located in Yichang, Hubei Province, China. The dam is one of the largest hydropower stations in the world, with an elevation of 185 meters and a water storage elevation of 175 meters. | Junqi Liu Chen Lin Shan Dong Ruixue Feng Aijun Su Jinghui Cui Shupeng Yu | 2023 | Journal of Earth Science2023，34，4： | 0 |
| 17 | Stock Price Forecasting: An Echo State Network Approach显示文摘Forecasting stock prices using deep learning models suffers from pro-blems such as low accuracy,slow convergence,and complex network structures.This study developed an echo state network(ESN)model to mitigate such pro-blems.We compared our ESN with a long short-term memory(LSTM)network by forecasting the stock data of Kweichow Moutai,a leading enterprise in China’s liquor industry.By analyzing data for 120,240,and 300 days,we generated fore-cast data for the next 40,80,and 100 days,respectively,using both ESN and LSTM.In terms of accuracy,ESN had the unique advantage of capturing non-linear data.Mean absolute error(MAE)was used to present the accuracy results.The MAEs of the data forecast by ESN were 0.024,0.024,and 0.025,which were,respectively,0.065,0.007,and 0.009 less than those of LSTM.In terms of con-vergence,ESN has a reservoir state-space structure,which makes it perform faster than other models.Root-mean-square error(RMSE)was used to present the con-vergence time.In our experiment,the RMSEs of ESN were 0.22,0.27,and 0.26,which were,respectively,0.08,0.01,and 0.12 less than those of LSTM.In terms of network structure,ESN consists only of input,reservoir,and output spaces,making it a much simpler model than the others.The proposed ESN was found to be an effective model that,compared to others,converges faster,forecasts more accurately,and builds time-series analyses more easily. | Guang Sun Jingjing Lin Chen Yang Xiangyang Yin Ziyu Li Peng Guo Junqi Sun Xiaoping Fan Bin Pan | 2021 | Computer Systems Science & Engineering2021，36，3： | 0 |
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