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| 1 | H7N9 virulent mutants detected in chickens in China pose an increased threat to humans显示文摘 | Jianzhong Shi Guohua Deng Huihui Kong Chunyang Gu Shujie Ma Xin Yin Xianying Zeng Pengfei Cui Yan Chen Huanliang Yang Xiaopeng Wan Xiurong Wang Liling Liu Pucheng Chen Yongping Jiang Jinxiong Liu Yuntao Guan Yasuo Suzuki Mei Li Zhiyuan Qu Lizheng Guan Jinkai Zang Wenli Gu Shuyu Han Yangming Song Yuzhen Hu Zeng Wang Linlin Gu Wenyu Yang Libin Liang Hongmei Bao Guobin Tian Yanbing Li Chuanling Qiao Li Jiang Chengjun Li Zhigao Bu Hualan Chen | 2017 | Cell Research2017，27，12： | 70 |
| 2 | A Novel Orthogonal LoRa Multiple Access Algorithm for Satellite Internet of Things显示文摘In recent years,LoRa has been extensively researched in the satellite Internet of Things(IoT).However,the multiple access technology of LoRa is still one of the bottlenecks of satellite IoT.To improve the multiple access performance of LoRa satellite IoT,based on the orthogonality of LoRa symbols in the fractional domain,this paper proposes a low complexity Orthogonal LoRa Multiple Access(OLMA)algorithm for multiple LoRa users occupying the same frequency bandwidth.The algorithm introduces the address code to divide the fractional bandwidth into multiple parts,and the OLMA users with different address codes occupy different parts to transmit the information code,thus avoiding mutual interference caused by collisions in the same frequency bandwidth.The multiple access capability of OLMA can be flexibly configured only by simply adjusting the length of the address code according to the actual application requirements of data transmission.Theoretical analysis and simulation results show that the OLMA algorithm can greatly improve the multiple access capability and the total transmission bit rate of LoRa IoT without changing the existing LoRa modulation parameters and process. | Chengwen Zhang Liankai Wang Libin Jiao Shipeng Wang Jun Shi Jia Yue | 2022 | China Communications2022，19，3： | 4 |
| 3 | A novel magnetic silica supported spinel ferrites NiFe2O4 catalyst for heterogeneous Fenton-like oxidation of rhodamine B显示文摘A series of spinel fe rrites magnetic nanopa rticles NiFe2 O4 we re synthesized as the heterogeneous Fentonlike catalyst by hydrothermal method and then NiFe2 O4@SiO2 catalysts were obtained by the modification of NiFe2 O4 via micro emulsion method.XRD,VSM,FTIR,SEM,TEM,BET and XPS were carried to analyze the difference between the above two catalysts.NiFe2 O4@SiO2 catalyst exhibited the higher catalytic activity than NiFe2 O4 for the degradation of Rhodamine B owe to the outer Si02 layers surface,the more important is both of them showed the better catalytic performance when at neutral pH environment. | Jifeng Qu Tinghua Che Libin Shi Qinghua Lu Suitao Qi | 2019 | Chinese Chemical Letters2019，30，6： | 3 |
| 4 | DC-CIK联合化疗治疗非小细胞肺癌的临床疗效评价(英文)显示文摘Objective: The aim of the study was to evaluate the safety and therapeutic effects of autologous dendritic cells co-cultured with cytokine-induced killer cells (DC-CIK) combined with chemotherapy in advanced non-small cell lung cancer (NSCLC) patients. Methods: Fifty patients with advanced NSCLC (stages III to IV), who had received therapies in our Center (Department of Biotherapy, Affiliated to Cancer Hospital of Shanxi Medical University, Taiyuan, China) from August 2008 to January 2010, were treated by DC-CIK + chemotherapy as the combined treatment group; fifty advanced NSCLC patients treated with chemotherapy at the same time served as controls. The immunologic function, short-term therapeutic effects, the 1-year survival rate, the life quality, the chemotherapy side effects were compared between the two groups, the safety and therapeutic effects of DC-CIK cells therapy were observed too. Results: There was no obvious change of subsets of T cells in peripheral blood before and after therapy in DC-CIK + chemotherapy group, and IFN-γ was improved after therapy in this group (P < 0.05); in chemotherapy alone group, the ratios of CD3+CD4+, CD3+CD8+, CD3-CD56+ cells and the secretion of IL-2, TNF-α decreased significantly after therapy (P < 0.05); the ratios of CD3+CD8+, CD3+CD56+ were improved after cell culture (P < 0.05). The disease control rate (DCR) of DC-CIK + chemotherapy group was higher than that in the chemotherapy alone group (78.0% vs 56.0%, P < 0.05); the 1-year survival rates of DC-CIK + chemotherapy group and chemotherapy alone group were 50% and 44% respectively, had no significant difference. Compared with chemotherapy alone group, the occurrence of chemotherapy side effects (including bone marrow suppression, nausea and vomiting, peripheral nerve toxicity) was less in the DC-CIK + chemotherapy group (P < 0.05). The physical and appetite were better in DC-CIK + chemotherapy group after therapy. Conclusion: To compare with simple chemotherapy, DC-CIK + chemotherapy for advanced NSCLC is safe and effective, and it can improve patients' life quality and remission rate, and prolong their survival time. | Junping Zhang Guanghua Mao Yaping Han Xiaoling Yang Huijing Feng Linzi Jia Ting Zhi Yan Xiao Libin Zhang Jiangtao Wang Tianliang Shi | 2012 | The Chinese-German Journal of Clinical Oncology2012，11，2： | 3 |
| 5 | H7N9 Influenza Viruses Are Transmissible in Ferrets by Respiratory Droplet显示文摘 | Qianyi Zhang Jianzhong Shi Guohua Deng Jing Guo Xianying Zeng Xijun He Huihui Kong Chunyang Gu Xuyong Li Jinxiong Liu Guojun Wang Yan Chen Liling Liu Libin Liang Yuanyuan Li Jun Fan Jinliang Wang Wenhui Li Lizheng Guan Qimeng Li Huanliang Yang Pucheng Che | 2013 | Science2013，，6144： | 1 |
| 6 | Bearing Failure Optimization of Composite Double-Lap Bolted Joints Based on a Three-Step Strategy Marked By Feasible Region Reduction and Model Decoupling显示文摘To minimize the mass and increase the bearing failure load of composite double-lap bolted joints,a three-step optimization strategy including feasible region reduction,optimization model decoupling and optimization was presented.In feasible region reduction,the dimensions of the feasible design region were reduced by selecting dominant design variables from numerous multilevel parameters by sensitivity analyses,and the feasible regions of variables were reduced by influence mechanism analyses.In model decoupling,the optimization model with a large number of variables was divided into various sub-models with fewer variables by variance analysis.In the third step,the optimization sub-models were solved one by one using a genetic algorithm,and the modified characteristic curve method was adopted as the failure prediction method.Based on the proposed optimization method,optimization of a double-lap single-bolt joint was performed using the ANSYS®code.The results show that the bearing failure load increased by 13.5%and that the mass decreased by 8.7%compared with those of the initial design of the joint,which validated the effectiveness of the three-step optimization strategy. | Fengrui Liu Wanting Yao Xinhong Shi Libin Zhao Jianyu Zhang | 2020 | Computers, Materials & Continua2020，，2： | 1 |
| 7 | Identification of Global DNA Methylation Signatures in Glioblastoma-Derived Cancer Stem Cells显示文摘Glioblastoma(GBM)is the most common and most aggressive primary brain tumor in adults.The existence of a small population of stem-like tumor cells that efficiently propagate tumors and resist cytotoxic therapy is one proposed mechanism leading to the resilient behavior of tumor cells and poor prognosis.In this study,we performed an in-depth analysis of the DNA methylation landscape in GBMderived cancer stem cells(GSCs).Parallel comparisons of primary tumors and GSC lines derived from these tumors with normal controls(a neural stem cell(NSC)line and normal brain tissue)identified groups of hyper- and hypomethylated genes that display a trend of either increasing or decreasing methylation levels in the order of controls,primary GBMs,and their counterpart GSC lines,respectively.Interestingly,concurrent promoter hypermethylation and gene body hypomethylation were observed in a subset of genes including MGMT,AJAP1 and PTPRN2.These unique DNA methylation signatures were also found in primary GBM-derived xenograft tumors indicating that they are not tissue culture-related epigenetic changes.Integration of GSC-specific epigenetic signatures with gene expression analysis further identified candidate tumor suppressor genes that are frequently down-regulated in GBMs such as SPINT2,NEFM and PENK.Forced re-expression of SPINT2 reduced glioma cell proliferative capacity,anchorage independent growth,cell motility,and tumor sphere formation in vitro.The results from this study demonstrate that GSCs possess unique epigenetic signatures that may play important roles in the pathogenesis of GBM. | Eun-Joon Lee Prakash Rath Jimei Liu Dungsung Ryu Lirong Pei Satish K.Noonepalle Austin Y.Shull Qi Feng N.Scott Litofsky Douglas C.Miller Douglas C.Anthony Mark D.Kirk John Laterra Libin Deng Hong-Bo Xin Xinguo Wang Jeong-Hyeon Choi Huidong Shi | 2015 | Journal of Genetics and Genomics2015，42，7： | 1 |
| 8 | H7N9 Influenza Viruses Are Transmissible in Ferrets by Respiratory Droplet显示文摘 | Qianyi Zhang Jianzhong Shi Guohua Deng Jing Guo Xianying Zeng Xijun He Huihui Kong Chunyang Gu Xuyong Li Jinxiong Liu Guojun Wang Yan Chen Liling Liu Libin Liang Yuanyuan Li Jun Fan Jinliang Wang Wenhui Li Lizheng Guan Qimeng Li Huanliang Yang Pucheng Che | 2013 | Science2013，，6144： | 1 |
| 9 | Catalytic purification of acrylonitrile-containing exhaust gases from petrochemical industry by metal-doped mesoporous zeolites显示文摘 | Runduo Zhang Dongjun Shi Ning Liu Biaohua Chen Lianghua Wu Libin Wu Weimin Yang | 2015 | Catalysis Today2015，，： | 1 |
| 10 | 2017年中国出现的H7N9高致病性病毒的快速进化显示文摘文章简介为了防控H7N9病毒,中国2017年9月开始对鸡进行了H5/H7二价禽流感灭活疫苗。为了解H7N9病毒在中国家禽中的分布情况,研究团队进行了系统的禽流感病毒监测。2017年2月至2017年5月之间在379个活禽市场和665个家禽养殖场共采集30201份样品(其中活禽市场采集12504份. | Jianzhong Shi Guohua Deng Shujie Ma Xianying Zeng Xin Yin Mei Li Bo Zhang Pengfei Cui Yan Chen Huanliang Yang Xiaopeng Wan Liling Liu Pucheng Chen Yongping Jiang Yuntao Guan Jinxiong Liu Wenli Gu Shuyu Han Yangming Song Libin Liang Zhiyuan Qu Yujie Hou Xiurong Wang Hongmei Bao Guobin Tian Yanbing Li Li Jiang Chengjun Li 陈化兰 | 2019 | 科学新闻2019，0，2： | 1 |
| 11 | Development of Fe-Mn-Si-Cr-Ni shape memory alloy with ultrahigh mechanical properties and large recovery strain by laser powder bed fusion显示文摘This work systematically studied the effect of volumetric energy density E on the densification,mi-crostructures,tensile mechanical properties,and shape memory performance of a Fe-Mn-Si-Cr-Ni shape memory alloy(SMA)fabricated by laser powder bed fusion(L-PBF).An E of 90-265 J/mm3 is suggested to fabricate the Fe-Mn-Si-Cr-Ni SMA with minor metallurgical defects and a high relative density of above 99%.The increase in E can promote the formation of the primaryγaustenite and the solid phase trans-formation from the primaryδferrite to theγaustenite,which helps to achieve a nearly complete y austenitic microstructure.The increase in E also contributes to fabricating the Fe-Mn-Si-Cr-Ni SMA with superior comprehensive mechanical properties and shape memory performance by L-PBF.The Fe-Mn-Si-Cr-Ni SMA with a combination of good ductility of around 30%,high yield strength of above 480 MPa,an ultrahigh ultimate tensile strength of above 1 GPa,and large recovery strain of about 6%was manu-factured by L-PBF under a high E of 222-250 J/mm^(3).The good shape memory effect,excellent compre-hensive mechanical properties,and low cost of Fe-Mn-Si-Cr-Ni SMAs,as well as the outstanding ability to fabricate complex structures of L-PBF technology,provide a solid foundation for the design and fabri-cation of novel intelligent structures. | Xiao Yang Lijin Cheng Huabei Peng Bingnan Qian Lei Yang Yunsong Shi Annan Chen Zhengyan Zhang Libin Zhao Ning Hu Chunze Yan Yusheng Shi | 2023 | Journal of Materials Science & Technology2023，，19： | 0 |
| 12 | Highly efficient H-bonding charge-transfer complex for microsupercapacitors under extreme conditions of low temperatures显示文摘Owing to sluggish ionic mobility at low temperatures, supercapacitors, as well as other energy-storage devices, always suffer from severe capacity decay and even failure under extreme low-temperature circumstances. Solar-thermal-enabled self-heating promises an attractive approach to overcome this issue.Here, we report a unique H-bonding charge-transfer complex with a high photothermal conversion efficiency of 79.5% at 405 nm based on chloranilic acid and albendazole. Integrated with a microsupercapacitor, the chloranilic acid-albendazole complex(CAC) film prompts an apparent temperature increase of 22.7 °C under 1 sun illumination at-32.6 °C, effectively elevating the working temperature of devices.As a result, the rate capability of the microsupercapacitor has been significantly improved with a 17-fold increase in capacitance at a current density of 60 μA cm^(-2), leading to outstanding low-temperature performances. Importantly, the integrated device is capable of working at a low temperature of-30 °C in the open air, which demonstrates the potential of CAC in practical applications for low-temperature ultracapacitive energy-storage devices. | Libin Wang Ting Shu Songtao Guo Shi Chen Yingjun Jiang Xianluo Hu | 2020 | Journal of Energy Chemistry2020，29，12： | 0 |
| 13 | Analysis of amino acid enantiomers in ambient aerosols:Effects and removal of coexistent aerosol matrix显示文摘Amino acids(AAs)including D-and L-enantiomers are a group of organic nitrogen species in ambient aerosol.Due to the low abundances of AAs(level of ng/m^(3))and the matrix effects by coexistent components,it is challenging to quantify AA enantiomers in ambient aerosols especially under pollution conditions.In this study,we present an optimized method for analyzing AA enantiomers in atmospheric aerosol samples including a pretreatment process and the detection by high performance liquid chromatography coupled to a fuorescence detector(HPLC-FLD).Matrix effects caused by coexistent chemicals on AA enantiomers analysis in ambient aerosol samples were investigated especially for those collected in pollution episodes.The results revealed that the determination of AA enantiomers is significantly affected by the coexistent organic carbon(as a proxy of organic matter)and water-soluble ion of NH_(4)^(+).To remove the matrix effects,we applied a pretreatment using the solid phase extraction column coupled with alkaline adjustment to sample extract.After pretreatment,18 AAs including 6 pairs of D-and L-enantiomers(i.e.,leucine,isoleucine,valine,alanine,serine,and aspartic acid)can be successfully separated and quantified in aerosol samples by HPLC-FLD.The recoveries are in the range of 67%-106%.This method was successfully applied to the urban aerosol samples from pollution and non-pollution periods for AA enantiomers determination.We suggest that the concentrations of D-AAs and the ratio of D-AA/L-AA are indicative of the contribution of bacterial sources and the infuence of biomass burning. | Ying Li Xiaoying Li Libin Wu Luhan Shi ShanWang Pingqing Fu Yingyi Zhang Senchao Lai | 2024 | Journal of Environmental Sciences2024，，3： | 0 |
| 14 | Consensus on diagnostic criteria for Yin deficiency syndrome in hypertension:a modified Delphi study显示文摘OBJECTIVE:To reach consensus on the diagnostic criteria for Yin deficiency syndrome in hypertension(YDSH)patients by a modified Delphi method.METHODS:Our study was consistent with T/CACM 1032-2017.The methodology of RAND/UCLA appropriateness was used to develop consensus guidance statements.A nationwide panel of experienced clinical experts from 19 provinces was constructed.These experts were all prominent in Traditional Chinese Medicine(TCM)of cardiovascular diseases.This consensus process consisted of two rounds of questionnaires and a final round of consultation to analyze the weight score of each item.Moreover,the data extraction process is carried out independently by third-party researchers(LIANG Junya,SUN Yang,and DU Xiaona).When there is disagreement in all three rounds,the expert panel group(odd number)are invited to vote,and the one with more votes wins.In the questionnaires,participants were asked to rate the appropriateness of each syndrome item using a nine-point Likert scale.The consensus was defined as a panel median rating 1-3 or 7-9 without disagreement.And then the diagnostic criteria of YDSH were formed according to the weight score in the final round.RESULTS:Twenty-eight experts(84.8%)participated in the first round,and thirty-one(93.9%)finished the second round.After two rounds,the consensus of YDSH was reached on 11 items(25.6%),including symptoms,signs,and pulse condition.Twenty-one experts(63.6%)completed the final round in which they used a grading system for each item.Red tongue with scanty fur had the highest weighting(22.8%),followed by heat in the palms and soles(20.1%).CONCLUSIONS:The consensus-based diagnostic criteria for YDSH,formed by a modified Delphi method,can be widely incorporated in TCM.A further clinical study will be conducted to analyze the diagnosis value and cut-off score of our YDSH criteria. | HE Yun HE Jing XU Xiangru LI Haixiao SHI Rongwei LIANG Junya ZHOU Ying ZHU Yao CHEN Xiaohu TANG Shuhua XIAO Min ZHAN Libin PEI Yinghao JIANG Weimin | 2023 | Journal of Traditional Chinese Medicine2023，43，1： | 0 |
| 15 | LEAF项目建设状态报告显示文摘LEAF or the Low Energy heavy ion Accelerator Facility is a multidiscipline heavy ion research platform under construction at IMP.It is a 5 year National Major Instruments Research Program supported by National Science Foundation of China(NSFC)started in 2015.Oriented to the frontier research in Material Sciences,Astrophysics,Atomic Physics and Highly Charged Ion Physics,LEAF has been designed and constructed with the state of the art technologies for low energy heavy ion acceleration.This facility features a 45 GHz ECR ion source FECR,a heavy ion CW 4-vane radio frequency quadruple accelerator LRFQ,300 kV HV platform,LEBT,MEBT and several dedicated experimental terminals. | Sun Liangting Yang Yao Lu Liang Guo Yuhui Liu Xiaojun Jing Long Li Libin Sun Liepeng Gao Zheng Ma Hongyi Jin Xiaofeng Zhai Yuhan Xu Xianbo Shi Longbo Xing Chaochao Liu Yuting Zhu Tieming Hu Qiang Zhang Peng Zhang Xuezhen Fang Xing Jia Huan Zhang Bin Liu Chaodong Ma Yingming Zhao Bo Wu Beimin Zhu Li Li Jiaqing Lu Wang Guo Junwei Li Chenxing Wang Zhijun Dou Weiping Wu Junxia Zhang Zimin Yao Qinggao Wu Wei Zhou Zhongzu Zhang Junhui Ma Lizhen He Yuan Zhao Hongwei | 2018 | IMP & HIRFL Annual Report2018，，1： | 0 |
| 16 | Mediator complex components are frequent targets for genetic alterations in various types of human cancer显示文摘The Mediator co-activator complex is a highly conserved,multisubunit protein complex required for gene transcription by RNA polymerase Ⅱ(RNAPⅡ)in all eukaryotes(Allen and Taatjes,2015).This complex,which consists of at least 30 polypeptides,can be divided into four structurally distinct sub-modules including the head,middle,tail,and cyclin-dependent kinase 8(CDK8) | Libin Deng Cheng Zhang Duling Miao Xiaoli Tang Shiwen Luo Hong-Bo Xin Huidong Shi | 2017 | Journal of Genetics and Genomics2017，44，12： | 0 |
| 17 | LEAF项目建设状态报告显示文摘LEAF or the Low Energy heavy ion Accelerator Facility is a multidiscipline heavy ion research platform constructing at IMP.It is a 5-year National Major Instruments Research Program supported by National Science Foundation of China(NSFC)started in 2015.Oriented to the frontier research in material sciences,astrophysics,atomic physics and highly charged ion physics,LEAF has been designed and constructed with the state-of-the-art technologies for low energy heavy ion acceleration.This facility features a 45 GHz ECR ion source FECR,a heavy ion CW 4-vane radio frequency quadruple accelerator LRFQ,300 kV HV platform,LEBT,MEBT and several dedicated experimental terminals.The layout of LEAF is given in Fig.1. | Sun Liangting Lu Liang Jia Huan Yang Yao Zhang Bin Guo Yuhui Gao Zheng Ma Hongyi Jin Xiaofeng Zhu Tieming Hu Qiang Zhang Peng Zhang Xuezhen Fang Xing Jing Long Liu Chaodong Ma Yingming Zhao Bo Wu Beimin Liu Xiaojun Li Jiaqing Lu Wang Guo Junwei Yang Long Li Libin Sun Liepeng Shi Longbo Li Chenxing Ma Wei Wang Zhijun Dou Weiping Wu Junxia Zhang Zimin Yao Qinggao Wu Wei Zhou Zhongzu Zhang Junhui Ma Lizhen He Yuan Zhao Hongwei | 2017 | IMP & HIRFL Annual Report2017，，1： | 0 |
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