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| 1 | Stage and size using magnetic resonance imaging and endosonography in neoadjuvantly-treated rectal cancer显示文摘AIM: To assess the stage and size of rectal tumours using 1.5 Tesla (1.5T) magnetic resonance imaging (MRI) and three-dimensional (3D) endosonography (ERUS). METHODS: In this study, patients were recruited in a phaseⅠ/Ⅱ trial of neoadjuvant chemotherapy for biopsy-proven rectal cancer planned for surgical resection with or without preoperative radiotherapy. The feasibility and accuracy of 1.5T MRI and 3D ERUS were compared with the histopathology of the fixed surgical specimen (pathology) to determine the stage and size of the rectal cancer before and after neoadjuvant chemotherapy. A Philips Intera 1.5T with a cardiac 5-channel synergy surface coil was used for the MRI, and a B-K Medical Falcon 2101 EXL 3D-Probe was used at 13 MHz for the ERUS. Our hypothesis was that the staging accuracy would be the same when using MRI, ERUS and a combination of MRI and ERUS. For the combination, MRI was chosen for the assessment of the lymph nodes, and ERUS was chosen for the assessment of perirectal tissue penetration. The stage was dichotomised into stageⅠ and stage Ⅱ or greater. The size was measured as the supero-inferior length and the maximal transaxial area of the tumour. RESULTS: The staging feasibility was 37 of 37 for the MRI and 29 of 36 for the ERUS, with stenosis as a limiting factor. Complete sets of investigations were available in 18 patients for size and 23 patients for stage. The stage accuracy by MRI, ERUS and the combination of MRI and ERUS was 0.65, 0.70 and 0.74, respectively, before chemotherapy and 0.65, 0.78 and 0.83, respectively, after chemotherapy. The improvement of the post-chemotherapy staging using the combination of MRI and ERUS compared with the staging using MRI alone was significant (P = 0.046). The post-chemotherapy understaging frequency by MRI, ERUS and the combination of MRI and ERUS was 0.18, 0.14 and 0.045, respectively, and these differences were non-significant. The measurements of the supero-inferior length by ERUS compared with MRI were within 1.96 standard deviations of the difference between the methods (18 mm) for tumours smaller than 50 mm. The agreement with pathology was within 1.96 standard deviations of the difference between imaging and pathology for all tumours with MRI (15 mm) and for tumours that did not exceed 50 mm with ERUS (22 mm). Tumours exceeding 50 mm in length could not be reliably measured by ERUS due to the limit in the length of each recording. CONCLUSION: MRI is preferable to use when assessing the size of large or stenotic rectal tumours. However, staging accuracy is improved by combining MRI with ERUS. | Torbjrn Swartling Peter Klebo Kristoffer Derwinger Bengt Gustavsson Gran Kurlberg | 2013 | World Journal of Gastroenterology2013，19，21： | 9 |
| 2 | Use of the semipermeable membrane device as an in situ sampler of waterborne bioavailable PCDD and PCDF residues at sub-parts-per-quadrillion concentrations显示文摘 | Lebo J A Gale R W Petty J D | 1995 | Environ Sci Teehnol1995，29，11： | 1 |
| 3 | Metamemory judgments and thebenefits of repeated study : Improving recall predictionsthrough the activation of appropriate knowledge 显示文摘 | Tiede H L Leboe J P | 2009 | Jour-nal of Experimental Psychology : Learning Memory andCognition2009，35，3： | 1 |
| 4 | A Practical Guide to Experience-Sampling Procedures显示文摘 | Tamlin Conner Christensen Lisa Feldman Barrett Eliza Bliss-Moreau Kirsten Lebo Cynthia Kaschub | 2003 | Journal of Happiness Studies2003，，1： | 1 |
| 5 | Development of the permeability/ performance reference compounds approach for in situ calibration of semipermeable membrane devices 显示文摘 | Huekins J N Petty J D Lebo J A | 2002 | Environ Sci & Technol2002，36，： | 1 |
| 6 | Dose-escalation study of rivaroxaban (BAY 59-7939) – an oral, direct Factor Xa inhibitor – for the prevention of venous thromboembolism in patients undergoing total hip replacement显示文摘 | Bengt I. Eriksson Lars C. Borris Ola E. Dahl Sylvia Haas Menno V. Huisman Ajay K. Kakkar Frank Misselwitz Eva Muehlhofer Peter K?lebo | 2007 | Thrombosis Research2007，，5： | 1 |
| 7 | Ecdysone receptor acts infruitless expressing neurons to mediate (Drosophila) courtship behaviors 显示文摘 | Dalton JE Lebo MS Sanders LE | 2009 | Current Biology2009，19，： | 1 |
| 8 | Commercial use of lignin-based materia-ls显示文摘 | GARGULAK J D LEBO S E | 2000 | Lignin:Historical Biological and Materials Perspectives2000，742，： | 1 |
| 9 | A novel lipopolysaccharide-induced transcription factor regulating tumor necrosis factor α gene expression: Molecular cloning, sequencing, characterization, and chromosomal assignment显示文摘 | MYOKAI F TAKASHIBA S LEBO R | 1999 | Proceedings of the National Academy of Sciences of the United States of America1999，96，8： | 1 |
| 10 | Laser and target experiments on KrF GARPUN laser installation at FIAN显示文摘 | Zvorykin V D Lebo I G | 1999 | Laserand Particle Beams1999，17，1： | 1 |
| 11 | Effective sampling system for polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in flue gas from municipal solid incinerators显示文摘 | LEBO J A GALE R W PETTY J D | 1995 | Environ Sci Technol1995，29，： | 1 |
| 12 | Duchenne/Becker muscular dystrophy carrier detection using quantitative PCR and fluorescence-based strategies显示文摘 | Robertson JM Lebo RV | 1993 | Am J Med Genet1993，48，： | 1 |
| 13 | Modeling phosphorus cycling in a well-mixed coastal-plain estuary显示文摘 | Lebo M E Sharp J H | 1992 | Est Coastal shelfSci1992，35，3： | 1 |
| 14 | TWC LOGD: A portal for linked open government data ecosystems显示文摘 | Li Ding Timothy Lebo John S. Erickson Dominic DiFranzo Gregory Todd Williams Xian Li James Michaelis Alvaro Graves Jin Guang Zheng Zhenning Shangguan Johanna Flores Deborah L. McGuinness James A. Hendler | 2011 | Web Semantics: Science Services and Agents on the World Wide Web2011，，3： | 1 |
| 15 | Acylphloroglucinol and xanthones from Hypericum ellipticum 显示文摘 | Kylie Manning Elyse Petrunak Michelle Lebo | 2011 | Phytochemistry2011，，： | 1 |
| 16 | On misattributing good remembering to a happy post: an investigation into the cognitive roots of nostalgia显示文摘 | Leboe j p Ansons T I | 2006 | Emotion2006，，12： | 1 |
| 17 | Gene encoding human growth hormone-releasing factor precursor: structure, sequence and chromosomal assignment显示文摘 | Mayo K E Cerelli G M Lebo R N | 1985 | Proc Natl Acad Sci USA1985，82，： | 1 |
| 18 | Harvest Impacts on Forest Outflow in Coastal North Carolina显示文摘 | Lebo M E Herrmann R B | 1998 | Journal of Environmental Quality1998，27，6： | 1 |
| 19 | Outbreak of Beri- beri among African Union Troops in Mogadishu, Somalia 显示文摘 | Watson J T E1 Bushra H Lebo E J | 2011 | PLoS One2011，6，28： | 1 |
| 20 | On Misattributing Good Remem Bering to a Happy Post:An Investigation into the Cognitive Roots of Nostalgia 显示文摘 | Leboe J P Ausous T L | 2006 | Emotion2006，4，11： | 1 |
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