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| 1 | Global burden, distribution, and interventions for infectious diseases of poverty显示文摘Infectious diseases of poverty(IDoP)disproportionately affect the poorest population in the world and contribute to a cycle of poverty as a result of decreased productivity ensuing from long-term illness,disability,and social stigma.In 2010,the global deaths from HIV/AIDS have increased to 1.5 million and malaria mortality rose to 1.17 million.Mortality from neglected tropical diseases rose to 152,000,while tuberculosis killed 1.2 million people that same year.Substantial regional variations exist in the distribution of these diseases as they are primarily concentrated in rural areas of Sub-Saharan Africa,Asia,and Latin America,with geographic overlap and high levels of co-infection.Evidence-based interventions exist to prevent and control these diseases,however,the coverage still remains low with an emerging challenge of antimicrobial resistance.Therefore,community-based delivery platforms are increasingly being advocated to ensure sustainability and combat co-infections.Because of the high morbidity and mortality burden of these diseases,especially in resource-poor settings,it is imperative to conduct a systematic review to identify strategies to prevent and control these diseases.Therefore,we attempted to evaluate the effectiveness of one of these strategies,that is community-based delivery for the prevention and treatment of IDoP.In this paper,we describe the burden,epidemiology,and potential interventions for IDoP.In subsequent papers of this series,we describe the analytical framework and the methodology used to guide the systematic reviews,and report the findings and interpretations of our analyses of the impact of community-based strategies on individual IDoPs. | Zulfiqar A Bhutta Johannes Sommerfeld Zohra S Lassi Rehana A Salam Jai K Das | 2014 | Infectious Diseases of Poverty2014，3，1： | 21 |
| 2 | The conceptual framework and assessment methodology for the systematic reviews of community-based interventions for the prevention and control of infectious diseases of poverty显示文摘This paper describes the conceptual framework and the methodology used to guide the systematic reviews of community-based interventions(CBIs)for the prevention and control of infectious diseases of poverty(IDoP).We adapted the conceptual framework from the 3ie work on the‘Community-Based Intervention Packages for Preventing Maternal Morbidity and Mortality and Improving Neonatal Outcomes’to aid in the analyzing of the existing CBIs for IDoP.The conceptual framework revolves around objectives,inputs,processes,outputs,outcomes,and impacts showing the theoretical linkages between the delivery of the interventions targeting these diseases through various community delivery platforms and the consequent health impacts.We also describe the methodology undertaken to conduct the systematic reviews and the meta-analyses. | Zohra S Lassi Rehana A Salam Jai K Das Zulfiqar A Bhutta | 2014 | Infectious Diseases of Poverty2014，3，1： | 5 |
| 3 | Impact of community-based interventions for the prevention and control of malaria on intervention coverage and health outcomes for the prevention and control of malaria显示文摘In this paper,we aim to evaluate the effectiveness of community-based interventions(CBIs)for the prevention and management of malaria.We conducted a systematic review and identified 42 studies for inclusion.Twenty-five of the included studies evaluated the impact of the community-based distribution of insecticide-treated nets(ITNs),indoor residual spraying(IRS),or impregnated bed sheets;14 studies evaluated intermittent preventive therapy(IPT)delivered in community settings;two studies focused on community-based education for malaria prevention;and one study evaluated environmental management through drain cleaning.Our analysis suggests that,overall,the community-based delivery of interventions to prevent and control malaria resulted in a significant increase in ITNs ownership(RR:2.16,95%CI:1.86,2.52)and usage(RR:1.77,95%CI:1.48,2.11).However,usage of ITNs was limited to two-thirds of the population who owned them.Community-based strategies also led to a significant decrease in parasitemia(RR:0.56,95%CI:0.42,0.74),malaria prevalence(RR:0.46,95%CI:0.29,0.73),malaria incidence(RR:0.70,95%CI:0.54,0.90),and anemia prevalence(RR:0.79,95%CI:0.64,0.97).We found a non-significant impact on splenomegaly,birth outcomes(low birth weight,prematurity,stillbirth/miscarriage),anthropometric measures(stunting,wasting,and underweight),and mortality(all-cause and malaria-specific).The subgroup analysis suggested that community-based distribution of ITNs,impregnated bed sheets and IRS,and IPT are effective strategies.Qualitative synthesis suggests that high coverage could be achieved at a lower cost with the integration of CBIs with existing antenatal care and immunization campaigns.Community-based delivery of interventions to prevent and control malaria are effective strategies to improve coverage and access and reduce malaria burden,however,efforts should also be concerted to prevent over diagnosis and drug resistance. | Rehana A Salam Jai K Das Zohra S Lassi Zulfiqar A Bhutta | 2014 | Infectious Diseases of Poverty2014，3，1： | 2 |
| 4 | Drug development for meta-static castration-resistant prostate cancer: current sta-tus and future perspectives显示文摘 | Lassi K Dawson N A | 2011 | Future Oncol2011，7，4： | 1 |
| 5 | Methodology development for laboratory-scale exhaust gas catalyst studies on phosphoruspoisoning显示文摘 | Kroger V Lassi U Kynkaanniemi K | 2006 | Chemical Engineering Journal2006，120，12： | 1 |
| 6 | Update on castrate-resistant prostate cancer: 2010 显示文摘 | LASSI K DAWSON N A | 2010 | Curr Opin Oncol2010，22，3： | 1 |
| 7 | Drug development for metastatic castration-resistant prostate cancer: current status and future perspectives显示文摘 | Lassi K Dawson NA | 2011 | Future Oncol2011，7，4： | 1 |
| 8 | Emerging therapies in castrateresistant prostate cancer显示文摘 | Lassi K Dawson N A | 2009 | Curr Opin Oncol2009，21，3： | 1 |
| 9 | Framework for Sustainable Food Packaging Design显示文摘 | Kaisa Gr?nman Risto Soukka Terhen J?rvi‐K??ri?inen Juha‐Matti Katajajuuri Mika Kuisma Heta‐Kaisa Koivupuro Margareetta Ollila Marja Pitk?nen Olli Miettinen Frans Silvenius Rabbe Thun Helena Wessman Lassi Linnanen | 2013 | Packag Technol Sci2013，，4： | 1 |
| 10 | Community-based interventions for the prevention and control of helmintic neglected tropical diseases显示文摘In this paper,we aim to systematically analyze the effectiveness of community-based interventions(CBIs)for the prevention and control of helminthiasis including soil-transmitted helminthiasis(STH)(ascariasis,hookworms,and trichuriasis),lymphatic filariasis,onchocerciasis,dracunculiasis,and schistosomiasis.We systematically reviewed literature published before May 2013 and included 32 studies in this review.Findings from the meta-analysis suggest that CBIs are effective in reducing the prevalence of STH(RR:0.45,95%CI:0.38,0.54),schistosomiasis(RR:0.40,95%CI:0.33,0.50),and STH intensity(SMD:−3.16,95 CI:−4.28,−2.04).They are also effective in improving mean hemoglobin(SMD:0.34,95%CI:0.20,0.47)and reducing anemia prevalence(RR:0.90,95%CI:0.85,0.96).However,it did not have any impact on ferritin,height,weight,low birth weight(LBW),or stillbirths.School-based delivery significantly reduced STH(RR:0.49,95%CI:0.39,0.63)and schistosomiasis prevalence(RR:0.50,95%CI:0.33,0.75),STH intensity(SMD:−0.22,95%CI:−0.26,−0.17),and anemia prevalence(RR:0.87,95%CI:0.81,0.94).It also improved mean hemoglobin(SMD:0.24,95%CI:0.16,0.32).We did not find any conclusive evidence from the quantitative synthesis on the relative effectiveness of integrated and non-integrated delivery strategies due to the limited data available for each subgroup.However,the qualitative synthesis from the included studies supports community-based delivery strategies and suggests that integrated prevention and control measures are more effective in achieving greater coverage compared to the routine vertical delivery,albeit it requires an existing strong healthcare infrastructure.Current evidence suggests that effective community-based strategies exist and deliver a range of preventive,promotive,and therapeutic interventions to combat helminthic neglected tropical diseases(NTDs).However,there is a need to implement and evaluate efficient integrated programs with the existing disease control programs on a larger scale throughout resource-limited regions especially to reach the unreachable. | Rehana A Salam Hasina Maredia Jai K Das Zohra S Lassi Zulfiqar A Bhutta | 2014 | Infectious Diseases of Poverty2014，3，1： | 1 |
| 11 | Emerging therapies in castrate-re- sistant prostate cancer显示文摘 | LASSI K DAWSON NA | 2009 | Curr Opin Oncol2009，21，： | 1 |
| 12 | Update on castrate-resistant prostate cancer:2010显示文摘 | Lassi K Dawson NA | | 0，，3： | 1 |
| 13 | Update on castrate-resistant prostate cancer:2010显示文摘 | Lassi K Dawson NA | 2010 | Curr Opin Oncol2010，22，3： | 1 |
| 14 | Emerging therapies in castrate-resistant prostate cancer显示文摘 | Lassi K Dawson NA | 2009 | Curr Opin Oncol2009，21，3： | 1 |
| 15 | The effect of barium on the catalytic behaviour of fresh and aged Pd-Ba-OSC/Al2O3 catalysts 显示文摘 | KOLLI T LASSI U RAHKAMAA TOLONEN K | 2006 | Applied Catalysis A: Gener- al2006，29，12： | 1 |
| 16 | Thermodynamic equilibrium calculations of sulfur poisoning in Ce-O-S and La-O-S systems显示文摘 | KARLJALAINEN H LASSI U RAHKAMAA-TOLONEN K KROGER V KEISKI R L | 2005 | Catal Today2005，100，34： | 1 |
| 17 | Livestock methane emission: from the individual graz- ing animal through national inventoriers to the global methane cy- cle显示文摘 | Lassy K R | 2007 | Agric for Meteorol2007，142，： | 1 |
| 18 | Smoking cessation is associated with an increase in exhaled nitric oxide 显示文摘 | Robbins RA Millatmal T Lassi K | 1997 | Chest1997，112，： | 1 |
| 19 | Update on castrate-resistant prostate cancer: 2010显示文摘 | Lassi K Dawson NA | 2010 | Curr Opin Oncol2010，22，： | 1 |
| 20 | Community based interventions for the prevention and control of tuberculosis显示文摘In 2012,an estimated 8.6 million people developed tuberculosis(TB)and 1.3 million died from the disease.With its recent resurgence with the human immunodeficiency virus(HIV);TB prevention and management has become further challenging.We systematically evaluated the effectiveness of community based interventions(CBI)for the prevention and treatment of TB and a total of 41 studies were identified for inclusion.Findings suggest that CBI for TB prevention and case detection showed significant increase in TB detection rates(RR:3.1,95%CI:2.92,3.28)with non-significant impact on TB incidence.CBI for treating patients with active TB showed an overall improvement in treatment success rates(RR:1.09,95%CI:1.07,1.11)and evidence from a single study suggests significant reduction in relapse rate(RR:0.26,95%CI:0.18,0.39).The results were consistent for various study design and delivery mechanism.Qualitative synthesis suggests that community based TB treatment delivery through community health workers(CHW)not only improved access and service utilization but also contributed to capacity building and improving the routine TB recording and reporting systems.CBI coupled with the DOTS strategy seem to be an effective approach,however there is a need to evaluate various community-based integrated delivery models for relative effectiveness. | Ahmed Arshad Rehana A Salam Zohra S Lassi Jai K Das Imama Naqvi Zulfiqar A Bhutta | 2014 | Infectious Diseases of Poverty2014，3，1： | 0 |
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