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| 1 | Shunting branch of portal vein and stent position predict survival after transjugular intrahepatic portosystemic shunt显示文摘AIM:To evaluate the effect of the shunting branch of the portal vein(PV)(left or right)and the initial stent position(optimal or suboptimal)of a transjugular intrahepatic portosystemic shunt(TIPS).METHODS:We retrospectively reviewed 307 consecu5tive cirrhotic patients who underwent TIPS placement for variceal bleeding from March 2001 to July 2010 at our center.The left PV was used in 221 patients and the right PV in the remaining 86 patients.And,224 and83 patients have optimal stent position and sub-optimal stent positions,respectively.The patients were followed until October 2011 or their death.Hepatic encephalopathy,shunt dysfunction,and survival were evaluated as outcomes.The difference between the groups was compared by Kaplan-Meier analysis.A Cox regression model was employed to evaluate the predictors.RESULTS:Among the patients who underwent TIPS to the left PV,the risk of hepatic encephalopathy(P=0.002)and mortality were lower(P<0.001)compared to those to the right PV.Patients who underwent TIPS with optimal initial stent position had a higher primary patency(P<0.001)and better survival(P=0.006)than those with suboptimal initial stent position.The shunting branch of the portal vein and the initial stent position were independent predictors of hepatic encephalopathy and shunt dysfunction after TIPS,respectively.And,both were independent predictors of survival.CONCLUSION:TIPS placed to the left portal vein with optimal stent position may reduce the risk of hepatic encephalopathy and improve the primary patency rates,thereby prolonging survival. | Ming Bai Chuang-Ye He Xing-Shun Qi Zhan-Xin Yin Jian-Hong Wang Wen-Gang Guo Jing Niu Jie-Lai Xia Zhuo-Li Zhang Andrew C Larson Kai-Chun Wu Dai-Ming Fan Guo-Hong Han | 2014 | World Journal of Gastroenterology2014,20,3: | 26 |
| 2 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010,16,25: | 13 |
| 3 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014,5,2: | 5 |
| 4 | Pvu Ⅱ polymorphisms at the porcine estrogen receptor locus (ESR) 显示文摘 | Rothschild MF Larson RG Jacobson C | 1991 | Anita Genet1991,22,5: | 1 |
| 5 | Responding to emergencies:lessons learned and the need for analysis显示文摘 | Larson R C Metzger M D Cahn M F | 2006 | Interfaces2006,36,6: | 1 |
| 6 | The failure syndrome 显示文摘 | LARSON C M R C CLUTE | 1979 | American Journal of Small Business1979,4,2: | 1 |
| 7 | Testing the metals hypothesis in Spokane, Washington显示文摘 | CLAIBORN C S LARSON T SHEPPARD L | 2002 | Environ Health Perspect2002,110,4: | 1 |
| 8 | Nurse workingconditions,organizational climate,and intent to leave in ICUs : aninstrumental variable approach part I显示文摘 | Stone P Mooney-Kane C Larson E | 2007 | Health Serv Hes2007,42,3: | 1 |
| 9 | Copper isotope ratios in magmatic and hydrothermal ore-forming environments显示文摘 | Peter B Larson Kierran Maher Frank C Ramos Zhaoshan Chang Miguel Gaspar Lawrence D Meinert | 2003 | Chemical Geology2003,,3: | 1 |
| 10 | Minimally invasive plating of high-energy metaphyseal distal tibia fractuxe8显示文摘 | Collinge C Kuper M Larson K | 2007 | J Orthop Trauma2007,21,6: | 1 |
| 11 | Osteoporosis screening in postmenopausal women 50 to 64 years old: comparison of US Preventive Services Task Force strategy and two traditional strategies in the Women's Health Initiative 显示文摘 | Crandall C J Larson J Gourlay ML | 2014 | J Bone Miner Res2014,29,7: | 1 |
| 12 | Modeling infiltration during a steady rain显示文摘 | Mein R G Larson C L | 1973 | Water Resources Research1973,9,2: | 1 |
| 13 | Kinetics and heat transfer of CdZnTe Bridgman growth without wall contact 显示文摘 | ZHANG H LARSON JR D J WANG C L | 2003 | Journal of Crystal Growth2003,250,12: | 1 |
| 14 | Polycystin-1,STAT6,and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease显示文摘 | Low S H Vasanth S Larson C H | 2006 | Dev Cell2006,10,1: | 1 |
| 15 | Locating discretionary service facility(Ⅱ):minimizing inconvenience显示文摘 | Berman O Bertismas K Larson R C | 1995 | Operations Research1995,43,4: | 1 |
| 16 | Numerical model of longshore current for bar and trough beaches显示文摘 | LARSON M KRAUS N C | 1991 | Journal of Waterway Port Coastal and Ocean Engineering1991,117,4: | 1 |
| 17 | Bioavailability andefficacy of omeprazole given orally and by nasogastric tube显示文摘 | Larson C Cavuto NJ Flockhart DA | 1996 | Dig Dis Sci1996,41,3: | 1 |
| 18 | Aphroscopic management of femoroacetabular impinge- ment: early outcomes measures 显示文摘 | Larson C M Giveans M R | 2008 | Ar- throseopy2008,24,5: | 1 |
| 19 | A novel biomechanical model assessing continuous orthodontic archwire activation显示文摘 | Canales C Larson M Grauer D | 2013 | Am J Orthod Dentofacial Orthop2013,143,2: | 1 |
| 20 | Association of common variants in NPPA and NPPB with circulating natriuretic peptides and blood pressure显示文摘 | Newton-Cheh C Larson MG Vasan RS | 2009 | Nat Genet2009,41,3: | 1 |