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597篇 您的检索式:作者名="Lander E"
    题名 作者 年代 出处 被引量
1Ploidy regulation of gene expression显示文摘Galitski T Saldanha A J Styles C A Lander E S Fink G R 1999Science1999,285,:2
2胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
3Mapmaker:an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations显示文摘Lander E S P Green Abraham 1987Genomics1987,,1:1
4MAPMAKER:An interactive computer package for constructing primary genetic linkage maps of experimental and natural populations显示文摘LANDER E S GREEN P ABRAHAMSON J 1987Genomics1987,1,:1
5Toward more accu rate quartz cement models: The importance of euhedral ver sus noneuhedral growth rates显示文摘Lander R H Larese R E Bonnell L M 2008AAPG Bulletin2008,92,:1
6The optics of vitreous surgery显示文摘Landers MB 3rd Stefánsson E Wolbarsht ML 0,,05:1
7Initial Sequencing and Analysis of the Human Genome 显示文摘Lander E S Linton L M Birren B 2001Nature2001,409,:1
8Genetic dissection of complex traits : guide- lines for interpreting and reporting linkage results 显示文摘Lander E Kruglyak L 1995Nat Genet1995,11,:1
9Construction of muhilocus genetic maps in human s显示文摘Lander E S Green P 1987Proc Nat Acad Sci USA1987,84,:1
10Reactive oxygen species have a causal role in muhiple forms of insulin resistance 显示文摘Houstis N Rosen E D Lander E S 2006Nature2006,440,7086:1
11Resolution of quantitative traits into Mendelian factors by using a comp lete linkagemap of restriction fragment length polymorphisms 显示文摘Paterson A H Lander E S Hewitt J D 1988Nature1988,335,:1
12Issues in multi-Agent design systems显示文摘LANDER S E 1997Expert Intelligent System & Their Applications1997,12,2:1
13Mapmaker: An interactive computer package for constructing primary ge- netic linkage maps of experimental and natural popula- tions 显示文摘Lander E S Green P Abrahamson J 1987Genomics1987,1,:1
14Trust-building mechanisms utilized in outsourced IS development project:A case study 显示文摘Lander M C Purvis R L McCray G E 2004Information and Management2004,41,4:1
15MAPMAKER: an interactive computer package for constructing primary genetic maps of experimental and natural populations显示文摘Lander E S Green P Abrahamson J Barlow A Day M J Lincoln S E Newbury L 1987Genetics1987,1,:1
16Initial sequencing and analysis of the human genome显示文摘 Linton L M Birren B 2001Nature2001,409,6822:1
17MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations显示文摘Lander E S Green P Abrahamson J 1987Genomies1987,1,:1
18The genetic dissection of complex traits 显示文摘Lander E S Schork N J 1994Science1994,265,:1
19Resolution of quanti- tative traits into Mendelian factors by using a complete linkage map of restriction fragment length poiyrnorphisms 显示文摘Paterson A H Lander E S Hewitt J D 1988Nature1988,335,:1
20Issues in muhiagent design systems 显示文摘Lander S E 1997IEEE Expert1997,12,2:1
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