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| 1 | Management of rectal varices in portal hypertension显示文摘Rectal varices are portosystemic collaterals that form as a complication of portal hypertension, their prevalence has been reported as high as 94% in patients withextrahepatic portal vein obstruction. The diagnosis is typically based on lower endoscopy(colonoscopy or sigmoidoscopy). However, endoscopic ultrasonography has been shown to be superior to endoscopy in diagnosing rectal varices. Color Doppler ultrasonography is a better method because it allows the calculation of the velocity of blood flow in the varices and can be used to predict the bleeding risk in the varices. Although rare, bleeding from rectal varices can be life threatening. The management of patients with rectal variceal bleeding is not well established. It is important to ensure hemodynamic stability with blood transfusion and to correct any coagulopathy prior to treating the bleeding varices. Endoscopic injection sclerotherapy has been reported to be more effective in the management of active bleeding from rectal varices with less rebleeding rate as compared to endoscopic band ligation. Transjugular intrahepatic portsystemic shunt alone or in combination with embolization is another method used successfully in control of bleeding. Balloon-occluded retrograde transvenous obliteration is an emerging procedure for management of gastric varices that has also been successfully used to treat bleeding rectal varices. Surgical procedures including suture ligation and porto-caval shunts are considered when other methods have failed. | Kawtar Al Khalloufi Adeyinka O Laiyemo | 2015 | World Journal of Hepatology2015,7,30: | 3 |
| 2 | Obesity, weight change, and risk of adenoma recurrence: a prospective trial显示文摘 | A. Laiyemo C. Doubeni D. Badurdeen G. Murphy P. Marcus R. Schoen E. Lanza D. Smoot A. Cross | 2012 | Endoscopy2012,,09: | 2 |
| 3 | Ongoing colorectal cancer risk despite surveillance colonoscopy: the Polyp Prevention Trial Continued Follow-up Study显示文摘 | Keith Leung Paul Pinsky Adeyinka O. Laiyemo Elaine Lanza Arthur Schatzkin Robert E. Schoen | 2010 | Gastrointestinal Endoscopy2010,,1: | 2 |
| 4 | Colorectal cancer disparities: Issues, controversies and solutions显示文摘Colorectal cancer(CRC)is the second leading cause of cancer related deaths in the United States.There are significant differences in CRC incidence and mortality by race with the highest burden occurring among blacks.The underlying factors contributing to CRC disparities are multiple and complex.Studies have suggested that a higher prevalence of putative risk factors for CRC,limited access to healthcare services,lower utilization of healthcare resources and increased biological susceptibilities contribute to this disparity by race.This article reviews the factors associated with the disproportionally higher burden of CRC among blacks;addresses the controversies regarding the age to begin CRC screening and the screening modality to use for blacks;and proffers solutions to eliminate CRC disparity by race. | Venkata S Tammana Adeyinka O Laiyemo | 2014 | World Journal of Gastroenterology2014,20,4: | 2 |
| 5 | Atrophic gastritis and the risk of incident colorectal cancer显示文摘 | Adeyinka O. Laiyemo Farin Kamangar Pamela M. Marcus Philip R. Taylor Jarmo Virtamo Demetrius Albanes Rachael Z. Stolzenberg-Solomon | 2009 | Cancer Causes & Control2009,,1: | 1 |
| 6 | Non-steroidal anti-in- flammatory drugs and colorectal cnaeer risk in a large,prospective cohort显示文摘 | Ruder EH Laiyemo AO Graubard BI | 2011 | Am J GastroenteroI2011,106,7: | 1 |
| 7 | Non-steroidal anti-inflammatory drugs and colorectal cancer risk in a large ,prospective cohort 显示文摘 | Ruder EH Laiyemo AO Graubard BI | 2011 | Am J Gastroenterol2011,106,7: | 1 |
| 8 | Obesity,weight change,and risk of adenoma recurrence:a prospective trial显示文摘 | Laiyemo AO Doubeni C Badurdeen DS | 2012 | Endoscopy2012,44,9: | 1 |
| 9 | Contribution of behavioral risk factors and obesity to socioeconomic differences in colorectal cancer incidence显示文摘 | Doubeni CA Major JM Laiyemo AO | 2012 | J Natl Cancer Inst2012,104,: | 1 |
| 10 | The risk of colonic adenomas and colonic cancer in obesi-ty 显示文摘 | Laiyemo AO | 2014 | Best Pract Res Clin Gastroenterol2014,28,4: | 1 |
| 11 | Postpolypecto- my colonoscopy surveillance guidelines:predictive accuracy for ad- vanced adenoma at 4 years 显示文摘 | LAIYEMO AO MURPHY G ALBERT PS | 2005 | Ann Intern Med2005,145,6: | 1 |
| 12 | Obesity, weight change, and risk of adenoma recurrence : a prospective trial显示文摘 | Laiyemo AO Doubeni C Badurdeen DS | 2012 | En- doscopy2012,44,9: | 1 |
| 13 | Non-steroidal anti inflame matory drugs and colorectal cancer risk in a large,prospective cohort显示文摘 | Ruder Ell Laiyemo AO Graubard B1 | 2011 | Am J Gastroenterol2011,106,7: | 1 |
| 14 | Can optical diagnosis of small colon polyps be accurate? Comparing standard scope without narrow banding to high definition scope with narrow banding显示文摘AIM: To study the accuracy of using high definition(HD) scope with narrow band imaging(NBI) vs standard white light colonoscope without NBI(ST), to predict the histology of the colon polyps, particularly those < 1 cm.METHODS: A total of 147 African Americans patients who were referred to Howard University Hospital for screening or, diagnostic or follow up colonoscopy, during a 12-mo period in 2012 were prospectively recruited. Some patients had multiple polyps and total number of polyps was 179. Their colonoscopies were performed by 3 experienced endoscopists who determined the size and stated whether the polyps being removed were hyperplastic or adenomatous polyps using standard colonoscopes or high definition colonoscopes with NBI. The histopathologic diagnosis was reported by pathologists as part of routine care. RESULTS: Of participants in the study, 55(37%) were male and median(interquartile range) of age was 56(19-80). Demographic, clinical characteristics, past medical history of patients, and the data obtained by two instruments were not significantly different and two methods detected similar number of polyps. In ST scope 89% of polyps were < 1 cm vs 87% in HD scope(P = 0.7). The ST scope had a positive predictive value(PPV) and positive likelihood ratio(PLR) of 86% and 4.0 for adenoma compared to 74% and 2.6 for HD scope. There was a trend of higher sensitivity for HD scope(68%) compare to ST scope(53%) with almost the same specificity. The ST scope had a PPV and PLR of 38% and 1.8 for hyperplastic polyp(HPP) compared to 42% and 2.2 for HD scope. The sensitivity and specificity of two instruments for HPP diagnosis were similar.CONCLUSION: Our results indicated that HD scope was more sensitive in diagnosis of adenoma than ST scope. Clinical diagnosis of HPP with either scope is less accurate compared to adenoma. Colonoscopy diagnosis is not yet fully matched with pathologic diagnosis of colon polyp. However with the advancement of both imaging and training, it may be possible to increase the sensitivity and specificity of the scopes and hence save money for eliminating time and the cost of Immunohistochemistry/pathology. | Hassan Ashktorab Firoozeh Etaati Farahnaz Rezaeean Mehdi Nouraie Mansour Paydar Hassan Hassanzadeh Namin Andrew Sanderson Rehana Begum Kawtar Alkhalloufi Hassan Brim Adeyinka O Laiyemo | 2016 | World Journal of Gastroenterology2016,22,28: | 1 |
| 15 | BMI and the risk of colorectal adenoma in African‐Americans显示文摘 | Hassan Ashktorab Mansour Paydar Shahla Yazdi Hassan Hassanzadeh Namin Andrew Sanderson Rehana Begum Mohammad Semati Firoozeh Etaati Edward Lee Hassan Brim Anteneh Zenebe Gail Nunlee‐Bland Adeyinka O. Laiyemo Mehdi Nouraie | 2014 | Obesity2014,,5: | 1 |
| 16 | Post-menopausal vaginal angio-myofibroblastoma:a case report显示文摘 | Laiyemo R Disu S Vijaya G | 2005 | Arch Gynecol Obster2005,273,2: | 1 |
| 17 | Post- polypectomy colonoscopy surveillance guidelines: predic- tive accuracy for advanced adenomas at 4 years 显示文摘 | Laiyemo A O Murphy G Albert P S | 2008 | Ann Intern Med2008,148,6: | 1 |
| 18 | Post-menopausal vaginal angiomyofibroblastoma: a case report显示文摘 | Laiyemo R Disu S Vijaya G | 2005 | Arch Gynecol Obster2005,273,2: | 1 |
| 19 | Hyper- plastic polyps and the risk of adenoma recurrence in the polyp prevention trial 显示文摘 | Laiyemo A O Murphy G Sansbury L B | 2009 | Clin Gastroenterol Hepatol2009,7,2: | 1 |
| 20 | In Search of a Perfect Solution to Ensure that “No Colon Is Left Behind”显示文摘 | Adeyinka O. Laiyemo | 2012 | Digestive Diseases and Sciences2012,,2: | 1 |