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| 1 | Relative Contributions of Boundary-Layer Meteorological Factors to the Explosive Growth of PM2.5 during the Red-Alert Heavy Pollution Episodes in Beijing in December 2016显示文摘Based on observations of urban mass concentration of fine particulate matter smaller than 2.5 μm in diameter(PM_(2.5)), ground meteorological data, vertical measurements of winds, temperature, and relative humidity(RH), and ECMWF reanalysis data, the major changes in the vertical structures of meteorological factors in the boundary layer(BL) during the heavy aerosol pollution episodes(HPEs) that occurred in winter 2016 in the urban Beijing area were analyzed. The HPEs are divided into two stages: the transport of pollutants under prevailing southerly winds, known as the transport stage(TS), and the PM_(2.5) explosive growth and pollution accumulation period characterized by a temperature inversion with low winds and high RH in the lower BL, known as the cumulative stage(CS). During the TS, a surface high lies south of Beijing, and pollutants are transported northwards. During the CS, a stable BL forms and is characterized by weak winds, temperature inversion, and moisture accumulation. Stable atmospheric stratification featured with light/calm winds and accumulated moisture(RH > 80%) below 250 m at the beginning of the CS is closely associated with the inversion, which is strengthened by the considerable decrease in near-surface air temperature due to the interaction between aerosols and radiation after the aerosol pollution occurs. A significant increase in the PLAM(Parameter Linking Aerosol Pollution and Meteorological Elements) index is found, which is linearly related to PM mass change. During the first 10 h of the CS, the more stable BL contributes approximately 84% of the explosive growth of PM_(2.5) mass. Additional accumulated near-surface moisture caused by the ground temperature decrease, weak turbulent diffusion, low BL height, and inhibited vertical mixing of water vapor is conducive to the secondary aerosol formation through chemical reactions, including liquid phase and heterogeneous reactions, which further increases the PM_(2.5) concentration levels. The contribution of these reaction mechanisms to the explosive growth of PM_(2.5) mass during the early CS and subsequent pollution accumulation requires further investigation. | junting zhong xiaoye zhang yaqiang wang junying sun yangmei zhang jizhi wang kaiyan tan xiaojing shen haochi che lu zhang zhouxiang zhang xuefei qi huarong zhao sanxue ren yang li | 2017 | Journal of Meteorological Research2017，31，5： | 25 |
| 2 | Effect of Silicon on Growth, Physiology, and Cadmium Translocation of Tobacco (Nicotiana tabacum L.) in Cadmium-Contaminated Soil显示文摘Silicon(Si) offers beneficial effect on plants under cadmium(Cd) stress such as promoting plant growth and increasing resistance to heavy metal toxicity. In this study, a pot experiment was performed to study the role of Si in alleviating Cd toxicity in tobacco(Nicotiana tabacum L.) plants on a yellow soil taken from Guiyang, China. Nine treatments consisting of three concentrations of Cd(0, 1, and 5 mg kg^(-1)) together with three Si levels(0, 1, and 4 g kg^(-1)) were established. Plant growth parameters, Cd concentration,and the malondialdehyde(MDA), chlorophyll, and carotenoid contents were determined 100 d after transplanting of tobacco seedlings.Application of exogenous Si enhanced the growth of tobacco plants under Cd stress. When 5 mg kg^(-1) Cd was added, Si addition at 1 and 4 g kg^(-1) increased root, stem, and leaf biomass by 26.1%–43.3%, 33.7%–43.8%, and 50.8%–69.9%, respectively, compared to Si addition at 0 g kg^(-1). With Si application, the transfer factor of Cd in tobacco from root to shoot under both 1 and 5 mg kg^(-1) Cd treatments decreased by 21%. The MDA contents in the Si-treated tobacco plants declined by 5.5%–17.1% compared to those in the non-Si-treated plants, indicating a higher Cd tolerance. Silicon application also increased the chlorophyll and carotenoid contents by 33.9%–41% and 25.8%–47.3% compared to the Cd only treatments. Therefore, it could be concluded that Si application can alleviate Cd toxicity to tobacco by decreasing Cd partitioning in the shoots and MDA levels and by increasing chlorophyll and carotenoid contents, thereby contributing to lowering the potential health risks of Cd contamination. | LU Yingang MA Jun TENG Ying HE Juny Peter CHRISTIE ZHU Lingjia REN Wenjie ZHANG Manyun Shiping DENG | 2018 | Pedosphere2018，28，4： | 7 |
| 3 | Aerosol Hygroscopicity during the Haze Red-Alert Period in December 2016 at a Rural Site of the North China Plain显示文摘A humidification system was deployed to measure aerosol hygroscopicity at a rural site of the North China Plain during the haze red-alert period 17–22 December 2016. The aerosol scattering coefficients under dry [relative humidity(RH) < 30%] and wet(RH in the range of 40%–85%) conditions were simultaneously measured at wavelengths of450, 550, and 700 nm. It is found that the aerosol scattering coefficient and backscattering coefficient increased by only 29% and 10%, respectively when RH went up from 40% to 80%, while the hemispheric backscatter fraction went down by 14%, implying that the aerosol hygroscopicity represented by the aerosol scattering enhancement factor f(RH) is relatively low and RH exerted little effects on the aerosol light scattering in this case. The scattering enhancement factors do not show significant differences at the three wavelengths, only with an approximate 2% variation, suggesting that the aerosol hygroscopicity is independent of the wavelength. Aerosol hygroscopicity is highly dependent on the aerosol chemical composition. When there is a large mass fraction of inorganics and a small mass fraction of organic matter, f(RH) reaches a high value. The fraction of NO_3^- was strongly correlated with the aerosol scattering coefficient at RH = 80%, which suggests that NO_3^- played an important role in aerosol hygroscopic growth during the heavy pollution period. | Xuefei QI Junying SUN Lu ZHANG Xiaojing SHEN Xiaoye ZHANG Yangmei ZHANG Yaqiang WANG Haochi CHE Zhouxiang ZHANG Junting ZHONG Kaiyan TAN Huarong ZHAO Sanxue REN | 2018 | Journal of Meteorological Research2018，32，1： | 7 |
| 4 | Key features of new particle formation events at background sites in China and their influence on cloud condensation nuclei显示文摘 | Xiaojing SHEN Junying SUN Xiaoye ZHANG Yangmei ZHANG Lu ZHANG Ruxia FAN | 2016 | Frontiers of Environmental Science & Engineering2016，10，5： | 5 |
| 5 | HLS bunch current measurement system显示文摘Bunch current is an important parameter for studying the injection fill-pattern in the storage ring and the instability threshold of the bunch, and the bunch current monitor also is an indispensable tool for the top-up injection. A bunch current measurement (BCM) system has been developed to meet the needs of the upgrade project of Hefei Light Source (HLS). This paper presents the layout of the BCM system. The system based on a high-speed digital oscilloscope can be used to measure the bunch current and synchronous phase shift. To obtain the absolute value of bunch-by-bunch current, the calibration coefficient is measured and analyzed. Error analysis shows that the RMS of bunch current is less than 0.01 mA when bunch current is about 5 mA, which can meet project requirement. | YANG YongLiang MA TianJi SUN BaoGen LU Ping WANG JiGang ZOU JunYing TANG LeiLei | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，S2： | 3 |
| 6 | Neuroprotective effects of Ginkgo biloba dropping pills in Parkinson's disease显示文摘Parkinson's disease(PD) is the second most common neurodegenerative disease in the world;however,it lacks effective and safe treatments. Ginkgo biloba dropping pill(GBDP), a unique Chinese G. biloba leaf extract preparation, exhibits antioxidant and neuroprotective effects and has a potential as an alternative therapy for PD. Thus, the aims of this study were to evaluate the effects of GBDP in in vitro and in vivo PD models and to compare the chemical constituents and pharmacological activities of GBDP and the G. biloba extract EGb 761. Using liquid chromatography tandem-mass spectrometry, 46 GBDP constituents were identified. Principal component analysis identified differences in the chemical profiles of GBDP and EGb 761. A quantitative analysis of 12 constituents showed that GBDP had higher levels of several flavonoids and terpene trilactones than EGb 761, whereas EGb 761 had higher levels of organic acids.Moreover, we found that GBDP prevented 6-hydroxydopamine-induced dopaminergic neuron loss in zebrafish and improved cognitive impairment and neuronal damage in methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced PD mice. Although similar effects were observed after EGb 761 treatment,the neuroprotective effects were greater after GBDP treatment on several endpoints. In addition, in vitro results suggested that the Akt/GSK3β pathway may be involved in the neuroprotective effects of GBDP.These findings demonstrated that GBDP have potential neuroprotective effects in the treatment of PD. | Dingyi Yu Pengli Zhang Junying Li Ting Liu Yaodan Zhang Qingqing Wang Jianbing Zhang Xiaoyan Lu Xiaohui Fan | 2021 | Journal of Pharmaceutical Analysis2021，11，2： | 3 |
| 7 | Development and application of the new BPM system data processing program at Hefei light source显示文摘A data processing program has been applied for the new beam position monitor (BPM) system of the storage ring at Hefei Light Source (HLS). The new BPM system in the upgrade project will be equipped with Libera Brilliance BPM processors to replace the old Bergoz MX-BPM processors. The embedded Linux system on Libera has completed some important work, including instrument status check,data acquisition, position calculation, EPICS IOC data release,and so on. A new EPICS record type has been developed to recalculate the beam position with log-ratio method. The property of the new position data was analyzed in the time and frequency domain. The results show that the rms value of beam position measurement resolution can be up to submicron. Preliminary studies have been carried out on the measurement of the tune and the beam lifetime with this new BPM system. | MA Tianji YANG Yongliang SUN Baogen ZOU Junying LU Ping ZHOU Zeran XU Hongliang | 2012 | Nuclear Science and Techniques2012，23，5： | 2 |
| 8 | Case study of small scale polytropic index in the central plasma sheet显示文摘This paper studies the effective polytropic index in the central plasma sheet(CPS) by using the method of Kartalev et al.(2006), which adopts the denoising technique of Haar wavelet to identify the homogeneous MHD Bernoulli integral(MBI) and has been frequently used to study the polytropic relation in the solar wind. We chose the quiet CPS crossing by Cluster C1 during the interval 08:51:00–09:19:00 UT on 03 August 2001. In the central plasma sheet, thermal pressure energy per unit mass is the most important part in MBI, and kinetic energy of fluid motion and electromagnetic energy per unit mass are less important. In the MBI, there are many peaks, which correspond to isothermal or near isothermal processes. The interval lengths of homogenous MBI regions are generally less than 1 min. The polytropic indexes are calculated by linearly fitting the data of lnp and lnn within a 16 s window, which is shifted forward by 8 s step length. Those polytropic indexes with |R|≥0.8(R is the correlation coefficient between lnp and lnn) and p-value≤0.1 in the homogeneous regions are almost all in the range of [0, 1]. The mean and median effective polytropic indexes with high R and low p-value in homogeneous regions are 0.34 and 0.32 respectively, which are much different from the polytropic index obtained by traditional method(?trad=?0.15). This result indicates that the CPS is not uniform even during quiet time and the blanket applications of polytropic law to plasma sheet may return misleading value of polytropic index. The polytropic indexes in homogeneous regions with a high correlation coefficient basically have good regression significance and are thus credible. These results are very important to understand the energy transport in magnetotail in the MHD frame. | PANG XueXia CAO JinBin LIU WenLong MA YuDuan LU HaoYu YANG JunYing LI LiuYuan LIU Xu WANG Jing WANG TieYan YU Jiang | 2015 | Science China Earth Sciences2015，58，11： | 2 |
| 9 | Comparison of Submicron Particles at a Rural and an Urban Site in the North China Plain during the December 2016 Heavy Pollution Episodes显示文摘An extensive field experiment for measurement of physical and chemical properties of aerosols was conducted at an urban site in the Chinese Academy of Meteorological Sciences(CAMS) in Beijing and at a rural site in Gucheng(GC), Hebei Province in December 2016. This paper compares the number size distribution of submicron particle matter(PM1, diameter < 1 μm) between the two sites. The results show that the mean PM1 number concentration at GC was twice that at CAMS, and the mass concentration was three times the amount at CAMS. It is found that the accumulation mode(100–850 nm) particles constituted the largest fraction of PM1 at GC, which was significantly correlated with the local coal combustion, as confirmed by a significant relationship between the accumulation mode and the absorption coefficient of soot particles. The high PM1 concentration at GC prevented the occurrence of new particle formation(NPF) events, while eight such events were observed at CAMS. During the NPF events, the mass fraction of sulfate increased significantly, indicating that sulfate played an important role in NPF. The contribution of regional transport to PM1 mass concentration was approximately 50% at both sites, same as that of the local emission. However, during the red-alert period when emission control took place, the contribution of regional transport was notably higher. | Xiaojing SHEN Junying SUN Xiaoye ZHANG Yangmei ZHANG Yaqiang WANG Kaiyan TAN Peng WANG Lu ZHANG Xuefei QI Haochi CHE Zhouxiang ZHANG Junting ZHONG Huarong ZHAO Sanxue REN | 2018 | Journal of Meteorological Research2018，32，1： | 2 |
| 10 | Tailoring the microstructure,mechanical and tribocorrosion performance of (CrNbTiAlV)N_(x) high-entropy nitride films by controlling nitrogen flow显示文摘The(CrNbTiAlV)N_(x)high-entropy nitride films were fabricated by adjusting nitrogen flow via magnetron sputtering.The microstructure,mechanical,electrochemical and tribocorrosion performances of the films were studied.The results show that the films transform from amorphous to nanocrystalline structure as nitrogen flow increased.The nanocrystalline films show super hardness(>40 GPa)and adhesion strength(>50 N).The amorphous film has a pretty anti-corrosion in static corrosion,while not in tribocorrosion condition.The film deposited at nitrogen flow of 38 sccm exhibits the optimal tribocorrosion performance in artificial seawater,with the highest open circuit potential(∼−0.1 V vs.Ag/AgCl),the lowest friction coefficient(∼0.162)and wear rate(∼7.48×10^(−7)mm^(3)N^(−1)m^(−1)). | Cunxiu Zhang Xiaolong Lu Cong Wang Xudong Sui Yanfang Wang Haibin Zhou Junying Hao | 2022 | Journal of Materials Science & Technology2022，，12： | 2 |
| 11 | Double-lipase Catalyzed Synthesis of Kojic Dipalmitate in Organic Solvents显示文摘 | WANG Zhiyuan LUO Wen FU Junying LI Zhibing WANG Zhongming LU Pengmei | 2017 | Chemical Research in Chinese Universities2017，33，6： | 2 |
| 12 | Filtering images contaminated with Pep and salt type noise with pulse-coupled neural networks显示文摘 | Zhang Junying Lu Zhijun Shi Lin Dong Jiyang Shi Mei-hong | 2004 | Science in China Ser F Information Sciences2004，47，3： | 1 |
| 13 | Programmed albumin nanoparticles regulate immunosuppressive pivot to potentiate checkpoint blockade cancer immunotherapy显示文摘The therapeutic efficacy of programmed cell death protein 1/programmed cell death-ligand 1(PD-1/PD-L1)blockade immunotherapy is extremely dampened by complex immunosuppressive mechanisms including regulatory T cells(Treg),M2 macrophages(M2),and prostaglandin E2(PGE2).The pivotal roles of PGE2 have been recognized by directly inactivating CD8+T cells and indirectly inducing Treg and M2.Therefore,PGE2 abolishment through inactivating cyclooxygenase-2(COX-2)could be robust to sensitize tumour toward anti-PD-1/PD-L1 immunotherapy,which has gone into clinical trials.However,exploring this promising strategy in nanomedicine to enhance immunotherapy remains unrevealed.The key challenge to synergistically combine COX-2 inhibition and anti-PD-1/PD-L1 lies in the different pharmacokinetic profiles and the spatial obstacles since PD-1/PD-L1 interaction occurs extracellularly and COX-2 locates intracellularly.Thus,the programmed release nanoparticles(termed as Cele-BMS-NPs)are rationally designed,which are composed of pH-sensitive human serum albumin derivative,BMS-202 compound as PD-1/PD-L1 inhibitor,glutathione(GSH)-activatable prodrug of celecoxib(COX-2 inhibitor).The in vitro experiments demonstrate that this smart Cele-BMS-NPs could extracellularly release BMS-202 under the acidic tumour microenvironment,and the intracellularly release of celecoxib in response to the elevated GSH concentration inside tumour cells.After systemic administration,the intratumoral infiltration of CD8+T cells is significantly enhanced and meanwhile immunosuppressive M2,Treg,and PGE2 are reduced,thereby eliciting the anti-tumour immune responses toward low immunogenic tumours and postsurgical tumour recurrences. | Liandong Feng Li Yang Longjie Li Junying Xiao Nana Bie Chao Xu Jun Zhou Hongmei Liu Lu Gan Yuzhou Wu | 2022 | Nano Research2022，15，1： | 1 |
| 14 | Targeting Phosphatidylcholine-Specific Phospholipase C for Atherogenesis Therapy显示文摘 | HaiYing Li Lu Zhang DeLing Yin Yun Zhang JunYing Miao | 2010 | Trends in Cardiovascular Medicine2010，，5： | 1 |
| 15 | D609 Inhibits Progression of Preexisting Atheroma and Promotes Lesion Stability in Apolipoprotein E?/? Mice: A Role of Phosphatidylcholine-Specific Phospholipase in Atherosclerosis显示文摘 | Lu Zhang Jing Zhao Le Su Bin Huang Li Wang Hua Su Yun Zhang ShangLi Zhang JunYing Miao | 2010 | Arteriosclerosis Thrombosis and Vascular Biology2010，，3： | 1 |
| 16 | Interlayer ligand engineering of β-Ni(OH)2 for oxygen evolution reaction显示文摘Oxygen evolution reaction(OER)is a bottleneck process for many electrochemical devices due to the sluggish kinetics,for which advanced electrocatalysts should be carefully designed.Nickle-based materials have been extensively studied to catalyze OER.However,their performances are still below the expectation and the active sites are often controversial.Herein,we have successfully modulated the electronic and surface properties of layeredβ-Ni(OH)2 by the interlayer ligand engineering,aiming to design novel efficient electrocatalysts and unveil the catalysis mechanism.By one-step solvothermal reaction,alkoxyl substitutedβ-Ni(OH)2 with variable interlayer distances is obtained,and the ethoxyl substituted one(NiEt)shows great potential for efficient OER.With the assistance of powder X-ray diffraction and crystalline structure computational simulation,the formula of alkoxyl substitutedβ-Ni(OH)2 are determined.Operando X-ray absorption spectroscopy studies combined with ex-situ analyses revealed that the critical active species of NiEt is formed via hydroxylation and subsequent de-protonation,with high valent Niδ+(3<δ≤3.66).The corresponding catalytic reaction pathway and mechanism are proposed. | Junying He Yuqin Zou Yucheng Huang Chenhui Li Yanbo Liu Ling Zhou Chung-Li Dong Xia Lu Shuangyin Wang | 2020 | Science China Chemistry2020，63，11： | 1 |
| 17 | Auricular vagus nerve acupressure for patients with emotional distress under the COVID-19 pandemic:A smartphone-based,randomized controlled trial显示文摘Objective: To confirm whether self-administered AVNA treatment is effective in improving emotional distressunder the COVID-19 pandemic.Methods: A smartphone-based online, randomized, controlled trial was designed from 26 February 2020 to 28April 2020 in four study sites, including Wuhan, Beijing, Shenyang, and Guangzhou of China. Local residentswho had considerable emotional distress with a score of the Hospital Anxiety and Depression Scale (HADS) ≥9 were recruited. Participants were randomly assigned to three times of AVNA (n = 191) per day, in morning,around noon, and in evening or usual care (UC, n = 215) once daily for 14 days. The primary outcome was theresponse rate, which was the proportion of participants whose Hospital Anxiety and Depression Scale (HADS)score reduced from baseline by ≥ 50%. The assessment was conducted at baseline, 3 days, and 14 days.Results: The AVNA group had a markedly higher response rate than the UC group at 3 days (35.6% vs. 24.9%,P = 0.02) and at 14 days (70.7% vs. 60.6%, P = 0.02). The AVNA group showed significantly greater reductionin scores of HADS at the two measurement points and BAI at 3 days (P ≤ 0.03), with average respective effectsize of 0.217 and 0.195. Participants with AVNA spent less time falling asleep and rated their sleep qualitybeing remarkably higher than those with UC at endpoint.Conclusion: During COVID-19 pandemic period, treatment with self-administrated AVNA was more effectivethan UC in reducing emotional distress of isolated populations. These findings support self-administered AVNAas a treatment option for patients with emotional distress under the COVID-19 pandemic or other emergentevents. | Peijing Rong Lei Wang Lingling Yu Junying Wang Yan Ma Liting Wang Suxia Li Chunzhi Tang Liming Lu Liang Li Jiazi Dong Jiliang Fang Liwei Hou Zongshi Qin Xiaolan Su Zhangjin Zhang | 2021 | TMR Modern Herbal Medicine2021，4，2： | 1 |
| 18 | Negative Regulation of Vps34 by Cdk Mediated Phosphorylation显示文摘 | Tsuyoshi Furuya Minsu Kim Marta Lipinski Juying Li Dohoon Kim Tao Lu Yong Shen Lucia Rameh Bruce Yankner Li-Huei Tsai Junying Yuan | 2010 | Molecular Cell2010，，4： | 1 |
| 19 | Development of an integrating sphere calibration method for Cimel sunphotometers in China aerosol remote sensing network显示文摘Based on the integrating sphere traced from the National Institute of Standards and Technology(NIST,USA), a sphere calibration method and protocol for the China aerosol remote sensing network(CARSNET)Cimel sun photometer was established. Four CE318 sun photometers were verified using the proposed calibration method and operational protocol. The calibration results showed that the instrument coefficients differed by less than 3% for visible(~5% for infrared) wavelengths from the original ones stated by Cimel Electronique. In situ validation experiment data showed that radiances at ±6° measured by sun collimator(aureole) were consistent with those measured by sky collimator(sky), under both almucantar(ALMUC)^nd principal plane(PPLAN) scenarios. Differences at all wavelengths were less than 1%, indicating that the method and protocol are suitable for CARSNET field sun photometer calibration, and would benefit improvement of data quality and accuracy of network observations. | Ran Tao Huizheng Che Quanliang Chen Yaqiang Wang Junying Sun Xiaochun Zhang Sai Lu Jianping Guo Hong Wang Xiaoye Zhang | 2014 | Particuology2014，12，2： | 1 |
| 20 | The toughing action of comprehensive transformation on mixed mode Ⅱ-Ⅲ ceramics显示文摘 | Xinhua Ni Xiequan Liu Junying Wang Xiaobo Lu | 2005 | Key Engineering Materials2005，，280283： | 1 |
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