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272篇 您的检索式:作者名="LONG Bo"
    题名 作者 年代 出处 被引量
1ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer显示文摘Shunrong Ji Yi Qin Si Shi Xiangyuan Liu Hongli HU Hu Zhou Jing Gao Bo Zhang Wenyan Xu Jiang Liu Dingkong Liang Liang Liu Chen Liu Jiang Long Haijun Zhou Paul J Chiao Jin Xu Quanxing Ni Daming Gao Xianjun Yu 2015Cell Research2015,25,5:19
2Reversing drug resistance of soft tumor-repopulating cells by tumor cell-derived chemotherapeutic microparticles显示文摘颠倒使人重新住入肿瘤的房间(TRC ) 的药抵抗或起源的发展中的新奇途径像房间的癌症房间是迫切临床的需要改进癌症病人的结果。这里,我们显示出用肿瘤颠倒 TRC 的药抵抗的一条创新途径包含反肿瘤药的导出房间的 microparticles (T-MPs ) 。由比区分的癌症房间更可变形的优点, TRC 优先地收起 T-MPs 在进入房间以后释放反肿瘤药,它接着导致 TRC 的死亡。内在的机制包括防碍药流出并且支持这些药的原子入口。我们的调查结果在用有希望的临床的应用程序颠倒 TRC 的药抵抗在 T-MPs 的举起和一条新奇途径的有效性表明肿瘤房间柔软的重要性。Jingwei Ma Yi Zhang Ke Tang Huafeng Zhang Xiaonan Yin Yong Li Pingwei Xu Yanling Sun Ruihua Ma Tiantian Ji Junwei Chen Shuang Zhang Tianzhen Zhang Shunqun Luo Yang Jin Xiuli Luo Chengyin Li Hongwei Gong Zhixiong Long Jinzhi Lu Zhuowei Hu Xuetao Cao Ning Wang Xiangliang Yang Bo Huang 2016Cell Research2016,26,6:17
3Radiofrequency ablation for hepatic hemangiomas: A consensus from a Chinese panel of experts显示文摘Recent studies have shown that radiofrequency(RF) ablation therapy is a safe, feasible, and effective procedure for hepatic hemangiomas, even huge hepatic hemangiomas. RF ablation has the following advantages in the treatment of hepatic hemangiomas: minimal invasiveness, definite efficacy, high safety, fast recovery, relatively simple operation, and wide applicability. It is necessary to formulate a widely accepted consensus among the experts in China who have extensive expertise and experience in the treatment of hepatic hemangiomas using RF ablation, which is important to standardize the application of RF ablation for the management of hepatic hemangiomas, regarding the selection of patients with suitable indications to receive RF ablation treatment, the technical details of the techniques, therapeutic effect evaluations, management of complications, etc. A final consensus by a Chinese panel of experts who have the expertise of using RF ablation to treat hepatic hemangiomas was reached by means of literature review, comprehensive discussion, and draft approval.Jun Gao Rui-Fang Fan Jia-Yin Yang Yan Cui Jian-Song Ji Kuan-Sheng Ma Xiao-Long Li Long Zhang Chong-Liang Xu Xin-Liang Kong Shan Ke Xue-Mei Ding Shao-Hong Wang Meng-Meng Yang Jin-Jin Song Bo Zhai Chun-Ming Nin Shi-Gang Guo Zong-Hai Xin Jun Lu Yong-Hong Dong Hua-Qiang Zhu Wen-Bing Sun 2017World Journal of Gastroenterology2017,23,39:15
4Experimental quantum secure direct communication with single photons显示文摘Quantum secure direct communication is an important mode of quantum communication in which secret messages are securely communicated directly over a quantum channel.Quantum secure direct communication is also a basic cryptographic primitive for constructing other quantum communication tasks,such as quantum authentication and quantum dialog.Here,we report the first experimental demonstration of quantum secure direct communication based on the DL04 protocol and equipped with single-photon frequency coding that explicitly demonstrated block transmission.In our experiment,we provided 16 different frequency channels,equivalent to a nibble of four-bit binary numbers for direct information transmission.The experiment firmly demonstrated the feasibility of quantum secure direct communication in the presence of noise and loss.Jian-Yong Hu Bo Yu Ming-Yong Jing Lian-Tuan Xiao Suo-Tang Jia Guo-Qing Qin Gui-Lu Long 2016Light(Science & Applications)2016,5,1:14
5New mechanistic pathways for CO oxidation catalyzed by single-atom catalysts: Supported and doped Au1/ThO2显示文摘单个原子的催化剂为设计新高效的便宜催化剂兴趣大。我们调查了在 thoria 上支持的单个金原子催化的公司氧化(用密度的 Au/ThO 2) 和做的 ThO 2 有 Hubbard 类型所在地的库仑相互作用(DFT + U ) 的功能的理论。计算结果证明做 Au 的 ThO 2(111) 催化剂在三步经由 Eley-Rideal 机制为公司氧化展出显著催化活动,在决定率的步是 OCOO 的分解的地方 * 与 0.58 eV 的一个精力障碍中间。而且,我们的结果也在 O 2在表面,和煤气阶段的公司上仅仅在 Th 地点被吸附的 ThO 2(111),支持的金 adatom 上揭示公司氧化的新机制然后与激活的 O 2*直接反应形成是限制率的步的公司2,,与 0.46 eV 的一个障碍。没有公司和 O 2 coadsorption,公司氧化能发生在 Au 上,这被发现,它以前被认为关键中介。因此,这些结果在 5f 元素混合物 ThO 2(111) 支持的孤立的金原子上提供新卓见进公司氧化。这机制能帮助澄清公司氧化的催化周期,支持高效的便宜催化剂的设计,并且阐明 actinide 氧化物的氧化还原作用性质。Bo Long Yan Tang Jun Li 2016Nano Research2016,9,12:12
6The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment.ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart 2019Science China(Physics,Mechanics & Astronomy)2019,62,2:11
7Biodiversity-based development and evolution:the emerging research systems in model and non-model organisms显示文摘Evolutionary developmental biology,or Evo-Devo for short,has become an established field that,broadly speaking,seeks to understand how changes in development drive major transitions and innovation in organismal evolution.It does so via integrating the principles and methods of many subdisciplines of biology.Although we have gained unprecedented knowledge from the studies on model organisms in the past decades,many fundamental and crucially essential processes remain a mystery.Considering the tremendous biodiversity of our planet,the current model organisms seem insufficient for us to understand the evolutionary and physiological processes of life and its adaptation to exterior environments.The currently increasing genomic data and the recently available gene-editing tools make it possible to extend our studies to non-model organisms.In this review,we review the recent work on the regulatory signaling of developmental and regeneration processes,environmental adaptation,and evolutionary mechanisms using both the existing model animals such as zebrafish and Drosophila,and the emerging nonstandard model organisms including amphioxus,ascidian,ciliates,single-celled phytoplankton,and marine nematode.In addition,the challenging questions and new directions in these systems are outlined as well.Long Zhao Feng Gao Shan Gao Yujun Liang Hongan Long Zhiyi Lv Ying Su Naihao Ye Liusuo Zhang Chengtian Zhao Xiaoyu Wang Weibo Song Shicui Zhang Bo Dong 2021Science China(Life Sciences)2021,64,8:9
8Effect of cooling rate on microstructure,microsegregation and mechanical properties of cast Ni-based superalloy K417G显示文摘The effects of different solidification rates after pouring on the microstructures,microsegregation and mechanical properties of cast superalloy K417 G were investigated.Scheil-model was applied to calculate the temperature range of solidification.The casting mould with different casting runners was designed to obtain three different cooling rates.The microstructures were observed and the microsegregation was investigated.Also,high temperature tensile test was performed at 900?C and stress rupture test was performed at 950?C with the stress of 235 MPa.The results showed that the secondary dendrite arm spacing,microsegregation,the size and volume fraction of γ'phase and the size of γ/γ'eutectic increased with decreasing cooling rate,but the volume fraction of γ/γ' eutectic decreased.In the cooling rate range of 1.42?C s^(-1)–0.84?C s^(-1),the cast micro-porosities and carbides varied little,while the volume fraction and size of phase and γ/γ' eutectic played a decisive role on mechanical properties.The specimen with the slowest cooling rate of 0.84?C s^(-1) showed the best comprehensive mechanical properties.Li Gong Bo Chen Long Zhang Yingche Ma Kui Liu 2018Journal of Materials Science & Technology2018,34,5:9
9Controlling upconversion through interfacial energy transfer(IET):Fundamentals and applications显示文摘Photon upconversion has received substantial attention owing to its great promise in broad applications from bioimaging to other frontier fields like display,upconversion laser,information security and anticounterfeiting.A smart control and manipulation of the upconversion luminescence has always been a key topic,however,to date the most efficient mechanism for upconversion nanoparticles remains the energy transfer upconversion and recently reported energy migration mediated upconversion.Recently,we found that the interfacial energy transfer(IET)is also an efficient approach for enabling and tuning photon upconversion of lanthanide ions.Moreover,it can be used for the mechanistic understanding of the interionic interactions such as energy transfer and energy migration on the nanoscale.In this review,the recent advances of the research on the IET are summarized,the principles for designing IET process and typical examples are discussed together with its applications in both mechanistic research and frontier information security.The challenges and perspectives for future research are also commented.Bo Zhou Qiqing Li Long Yan Qinynuan Zhang 2020Journal of Rare Earths2020,38,5:8
10Generation of ready to use (RTU) products over China based on Landsat series data显示文摘Earth observation community has entered into the era of big data.Family of Landsat sensors have collected massive medium resolution satellite images,which are valuable for long-term land surface monitoring.In order to significantly reduce the magnitude of data processing for remote sensing data users,Landsat-based Ready to Use(RTU)products have been produced.Main RTU products,including orthorectified products,land surface reflectance,land surface temperature,large-area mosaic image,and standard image map products,are described.The resulting Landsat RTU products are hosted on the RSGS earth observation data sharing web site for free download(http://gffzz959b1a8e74bf485dhbuuqwubkcwu06nfn.ffgz.tsg.suse.edu.cn/rtu/).These new products will provide consistent,standardized,multi-decadal image data for robust land cover change detection and monitoring across the Earth sciences.In the coming years,CASEarth DataBank system will be constructed,which is an intelligent data service platform for providing not only the RTU products from multi-source satellite data,but also big earth data analysis methods.Guojin He Zhaoming Zhang Weili Jiao Tengfei Long Yan Peng Guizhou Wang Ranyu Yin Wei Wang Xiaomei Zhang Huichan Liu Bo Cheng Bo Xiang 2018Big Earth Data2018,2,1:8
11Test for the effects of three surfactants on the penetration ability of the calcium chloride and water glass Solutions in dust显示文摘1IntroductionCalciumchlorideisoftenusedinthefieldofsoilstabilizationandraisingdustcontrolbecauseitcanreactwithwaterglas(Wu,19...Wu Chao, Chen Jun liang, Zhou Bo, Wang Ping long Department of Resources Exploitation Engineering, Central South University of Technology, Changsha 410083, China 1998Journal of Environmental Sciences1998,10,4:8
12Heritable/conditional genome editing in C. elegans using a CRISPR-Cas9 feeding system显示文摘Pengpeng Liu Lijiang Long Kai Xiong Bo Yu Nannan Chang Jing-Wei Xiong Zuoyan Zhu Dong Liu 2014Cell Research2014,24,7:8
13Two New Steroidal Glycosides from Liriope muscari显示文摘Two new steroidal glycosides named Lm-4 (1) and Lm-5 (2) were isolated from the tubers of Liriope muscari. Their structures were elucidated by 1D and 2D NMR, ESI/MALDI- MS techniques, and chemical methods.Zhi Hong CHENG Tao WU Yin Long GUO Bo Yang YU Luo Shan XU 2006Chinese Chemical Letters2006,17,1:8
14Prospective randomized comparison of transumbilical two-port laparoscopic and conventional laparoscopic varicocele ligation显示文摘我们证实了一个新奇方法为精索静脉曲张把 transumbilical 称为二港口的 laparoscopic 精索静脉曲张结扎(TTLVL ) ,它仍然被需要评估。在这研究,有等级 II-III 的左自发的征兆的精索静脉曲张的 90 个病人随机根据分级系统的 Dubin 被分到 TTLVL (n = 45 ) 并且常规 laparoscopic 精索静脉曲张结扎(CLVL )(n = 45 ) 。人口统计, intraoperative,手术后,并且后续数据在二个组之间被记录并且比较。在二个组的所有过程没有 intraoperative 复杂并发症和没有变换成功地被完成打开外科。没有重要差别在起作用的时间被发现,恢复在二个组之间的阴囊的疼痛的移动,肠恢复,手术后的医院停留,和手术后的分辨率(P >0.05 ) 。然而,为 TTLVL 组的手术后的吝啬的视觉模拟疼痛规模分数都与 CLVL 相比手术后地是在 24 h, 48 h, 72 h,和 7 天的更少(P = 0.001, 0.010, 0.006,和 0.027,分别地) 。在手术后的月内的吝啬的耐心的疤评价问询表分数 3 为 CLVL 组与 32.1 相比为 TTLVL 组是 29.7 (P <0.001 ) 。没有阴囊的萎缩,在后续时期期间在两个组观察。学习证明 TTLVL 是为精索静脉曲张的治疗的 CLVL 的一种安全、可行、有效的最低限度地侵略的外科的选择。与 CLVL 相比, TTLVL 可以减少手术后伤害并且改善化妆结果。Guo-Xi Zhang Jan Yang Da-Zhi Long Min Liu Xiao-Feng Zou Yuan-Hu Yuan Ri-Hai Xiao Yi-Jun Xue Xin Zhong Quan-Liang Liu Fo-Lin Liu Bo Jiang Rui-Quan Xu Kun-Lin Xie 2017Asian Journal of Andrology2017,19,1:8
15Expression of MMP-2 and MMP-9 in retinoblastoma and their significance显示文摘AIM:To investigate the expression of matrix metallopr-oteinase-2(MMP-2) and matrix metalloproteinase-9(MMP-9) in retinoblastoma(Rb),and their relationships with tumor development stage.METHODS:Immunohistochemical technique was used to detect the expression of MMP-2 and MMP-9 in 41 cases of paraffin embedded Rb samples.Quantitative analysis of the expression of MMP-2 and MMP-9 was assessed by HMIAS-2000 Color Pathologic Analysis System.The differences of the expression of MMP-2 and MMP-9 in each clinical and pathological stage were analyzed statistically.RESULTS:In all the 41 Rb specimens,MMP-2 and MMP-9 expression was found in tumor cells.The expression of MMP-2 and MMP-9 was significantly higher in tumors with optic nerve invasion than in tumors without optic nerve invasion(P <0.05);the expression of MMP-2 and MMP-9 was significantly higher in tumors of extra-ocular stage than in tumors of glaucomatous stage or intra-ocular stage(P < 0.05).CONCLUSION:MMP-2 and MMP-9 exist in retinoblastoma cells.The level of MMP-2 and MMP-9 is related to optic nerve invasion and clinical stage of Rb,which suggests the expression of MMP-2 and MMP-9 could be connected to the invasion and development of tumor cells.Further research is needed for deeper understanding of the biological behavior and better evaluation of the prognosis of Rb.Hua Long, Fa-Gang Jiang 2011International Journal of Ophthalmology(English edition)2011,4,5:8
16Detection of serum IgM and IgG for COVID-19 diagnosis显示文摘Dear Editor,Infection with the novel coronavirus(SARS-CoV-2,which is the virus responsible for the coronavirus disease 2019(COVID-19))was first reported in Wuhan,China on December 31,2019.The outbreak of COVID-19 remains ongoing and was linked to more than 80,000 infected patients and more than 3,000 deaths in China as of March 7,2020(Holshue et al.,2020).Ling Zhong Junlan Chuan Bo Gong Ping Shuai Yu Zhou Yi Zhang Zhilin Jiang Dingding Zhang Xiaoqi Liu Shi Ma Yi Huang He Lin Qingwei Wang Lulin Huang Dan Jiang Fang Hao Juan Tang Chunqi Zheng Hua Yu Zhibin Wang Qi Jiang Tao Zeng Mei Luo Fanwei Zeng Fanxin Zeng Jianghai Liu Junxi Tian Yu Xu Tengxiang Long Kaiju Xu Xingxiang Yang Yuping Liu Yi Shi Li Jiang Zhenglin Yang 2020Science China(Life Sciences)2020,63,5:8
17Effect of tin addition on corrosion behavior of a low-alloy steel in simulated costal-industrial atmosphere显示文摘The effect of tin addition on the atmospheric corrosion behavior of a low-alloy steel in sim ulated coastalindustrial atm osphere has been investigated by indoor wet/dry cyclic corrosion test (CCT). The results indicate that tin addition can obviously make the steel substrate more resistant to atmospheric corrosion by suppressing the cathodic H^+ reduction reaction, and but tin addition is not of obvious beneficial effect when the steel is covered with a thicker rust layer during long-term corrosion process. The reason lies in the fact that the presence of un-reduced H^+ can lower the electrolyte pH value and lead to a loose and porous rust layer on tin-containing steel sample than that on tin-free steel sample. In addition, the 120 CCT cycles corrosion process of the two steels can be divided into three stages. Both the tin-free and tin-containing steels show an increasing corrosion rate during the initial corrosion stage and then exhibit a decreasing corrosion rate during the second and third corrosion stages. Moreover, tin addition makes the tin-containing steel rust layer have a higher amount of α-FeOOH and lower am ount of γ-FeOOH and Fe3O4 than the tin-free steel rust layer.Bo Liu Xin Mu Ying Yang Long Hao Xueyong Ding Junhua Dong Zhe Zhang Huaxing Hou Wei Ke 2019Journal of Materials Science & Technology2019,35,7:6
18Accurate mirror-based camera pose estimation with explicit geometric meanings显示文摘An accurate closed form solution is proposed to estimate camera pose by several mirrored reference object images acquired via a planar mirror under different unknown poses. Compared with state-of-the-art methods, our method is more accurate when there are more than three images and has explicit geometric meanings. This method also properly handles cases in which some of the mirror poses are parallel. The central idea is to minimize an error metric based on all reflections of rotation, which enables the camera rotation to be estimated directly by SVD of sum of mirrored camera rotations. After that, the camera translation is computed by solving a large system of linear equations to minimize object space collinearity error. Both synthesized data and real data experiments show the advantages of our approach.LI Xin LONG Gu Can GUO Peng Yu LIU Jin Bo ZHANG Xiao Hu YU Qi Feng 2014Science China(Technological Sciences)2014,57,12:6
19Optimization of cantilevered piezoelectric energy harvester with a fixed resonance frequency显示文摘Piezoelectric energy harvesting is widely used to scavenge vibration energy in the environment.For some vibration sources with fixed frequency,cantilevered harvester can generate the energy effectively,so the optimization theory for cantilevered harvester in such an application is needed.In this article,we present the theoretical and experimental studies of the cantilevered piezoelectric energy harvester with a fixed resonance frequency.An analytical model based on energy method is used to estimate the open-circuit voltage and generated energy.Considering that the harvester may be subjected to the static force or steady-state sinusoidal vibration excitation,static and dynamic analysis is performed for device structure to achieve efficient energy.In the analysis,the effects of geometrical dimension on the energy harvesting performance are discussed comprehensively.Eventually,a prototype is designed and fabricated using(1-x)Pb(Mg1/3Nb2/3)O3-xPbTiO3(PMN-PT)single crystal with ultrahigh piezoelectric properties and coupling factor.Performances of the cantilever with different clamped length are evaluated under sinusoidal vibration excitation,proving the good consistency between experimental results and theoretical prediction.The established analysis can provide useful guidelines for the structure design of cantilevered piezoelectric energy harvester with a fixed resonance frequency.LIANG Zhu XU ChunDong REN Bo DI WenNing LI Long LUO HaoSu CHEN Zhen SU Jun 2014Science China(Technological Sciences)2014,57,6:6
20Measurement-device-independent quantum secure direct communication显示文摘Quantum secure direct communication(QSDC)is a unique technique,which supports the secure transmission of confidential information directly through a quantum channel without the need for a secret key and for ciphertext.Hence this secure communication protocol fundamentally differs from its conventional counterparts.In this article,we report the first measurement-deviceindependent(MDI)QSDC protocol relying on sequences of entangled photon pairs and single photons.Explicitly,it eliminates the security loopholes associated with the measurement device.Additionally,this MDI technique is capable of doubling the communication distance of its conventional counterpart operating without using our MDI technique.We also conceive a protocol associated with linear optical Bell-basis measurements,where only two of the four Bell-basis states could be measured.When the number of qubits in a sequence reduces to 1,the MDI-QSDC protocol degenerates to a deterministic MDI quantum key distribution protocol.ZengRong Zhou Yu Bo Sheng PengHao Niu LiuGuo Yin GuiLu Long Lajos Hanzo 2020Science China(Physics,Mechanics & Astronomy)2020,63,3:6
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