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| 1 | Terrestrial input and nutrient change reflected by sediment records of the Changjiang River Estuary in recent 80 years显示文摘A variety of environmental problems have been observed in the Changjiang River Estuary and adjacent coastal area, including eutrophication, harmful algal blooms(HABs), and hypoxia in recent decades. Application of sedimentary biogenic element indicators on the study of paleoenvironment can reconstruct environmental evolution history of waters. Two 210Pb-dated cores were collected from the Changjiang River Estuary(S3) and adjacent coastal area(Z13), and total organic carbon(TOC), total nitrogen(TN), biogenic silicon(BSi), total phosphorus(TP) and phosphorus(P) species were analyzed. Three stages of environmental changes are deduced by the nutrient sedimentary records. First, nutrient concentration increased rapidly since the 1950 s, which attributed to agriculture development and overused chemical fertilizers. Second, nutrient concentration kept high and primary production began to promote during the 1960 s to 1980 s, while diatom abundance and proportion began to decline since the 1970 s, accompanied by reduced 23 Si O- concentration and flux from the river. Third, due to several dams and bridges constructed, river runoff and coastal hydrodynamic conditions reduced to a certain extent since the 1990 s, which aggravated the unbalance in nutrient structure. Multi-nutrient proxies in sediment can reflect the natural environm-ental changes as well as influence of human activities. | LI Junlong ZHENG Binghui HU Xupeng WANG Yiming DING Ye LIU Fang | 2015 | Acta Oceanologica Sinica2015，34，2： | 4 |
| 2 | Cloning, expression and protective immunity evalua-tion of the full-length cDNA encoding succinate dehydrogenase iron-sulfur protein of Schistosoma japonicum显示文摘1071-bp fragment was obtained from the Schistosoma japonicum (Chinese strain) adult cDNA library after the 3′ and 5′ ends of the incomplete expression sequence tag (EST) of succinate dehydrogenase iron-sulfur protein of Schistosoma japonicum (SjSDISP) were amplified by the anchored PCR with 2 pairs of primers designed according to the EST of SjSDISP and the sequence of multiclone sites of the library vector. Sequence analysis indicated that the fragment was a full-length cDNA with a complete open reading frame (ORF), encoding 278 amino acid residues. The fragment was cloned into prokary- otic expression vector pQE30, and subsequently sequenced and expressed in Escherichia coli. SDS-PAGE and Western-blot analyses showed that the recombinant protein was about 32 kD and could be recognized by the polyclonal antisera from rabbits immunized with Schistosoma japonicum adult worm antigen. Compared with the FCA controls, mice vaccinated with rSjSDISP (test) or rSjGST (posi- tive control) all revealed high levels of specific antibody and significant reduction in worm burden, liver eggs per gram (LEPG), fecal eggs per gram (FEPG) and intrauterine eggs. These results suggest that SjSDISP may be a novel and partially protective vaccine candidate against schistosomiasis. In contrast to the worm burden reduction rate, the higher degree of egg reduction rate in the test group also sug- gested that SjSDISP vaccine may primarily play a role in anti-embryonation or anti-fecundity immunity. | YU JunLong, WANG ShiPing, LI WenKai, DAI Gan, XU ShaoRui, HE Zhuo, PENG XianChu, ZHOU SongHua & LIU XueQin Department of Parasitology, Xiangya School of Medicine, Central South University, Changsha 410078, China | 2007 | Science China(Life Sciences)2007，50，2： | 4 |
| 3 | Mission-oriented dynamic optimization model of carrying spares for warship redundant system显示文摘Redundancy is a common structure for warship system,and it is an effective way to improve the reliability of the system.In this paper, warship system is taken as the object of study,based on the system reliability equivalence principle, a spares demand rate calculation method for redundant system is proposed through structure transformation. According to the system analysis method, the general modeling data structure of spares support echelon and system indenture is established, and the mission success probability is taken as the optimization target to build the dynamic optimization model of carrying spares during the process of multi-phase. By introducing the Lagrange multiplier, the spares weight, volume and cost are transformed to the single target of the spares total scale, and the initial Lagrange factors and its dynamic adjustment policy is proposed. In a given example, the main influence factors of the carrying spares project are analyzed, and the study results are in accordance with the reality, which can provide a new approach to mission-oriented carrying spares optimization for the redundant system. | RUAN Minzhi LI Hua WANG Junlong | 2018 | Journal of Systems Engineering and Electronics2018，29，3： | 4 |
| 4 | Parametric modeling of hypersonic ballistic data based on time varying auto-regressive model显示文摘For describing target motion in hypersonic vehicle defense,a parametric analyzing and modeling method on ballistic data is proposed based on time varying auto-regressive method.Ballistic data are regarded as non-stationary random signal,where the hidden internal law is studied.Firstly,ballistic data are decomposed into smooth linear trend signal and non-stationary periodic skip signal with ensemble empirical mode decomposition method to avoid mutual interference between different modal data.Secondly,the linear trend signal and the periodic skip signal are modeled separately.The linear trend signal is approximated by power function regressive estimator and the periodic skip signal is modeled based on time varying auto-regressive method.In order to determine optimal model orders,a novel method is presented based on information theoretic criteria and the criteria of minimizing the mean absolute error.Finally,the consistency test is conducted by investigating the time-frequency spectrum characteristics and statistical properties of outputs of the parametric model established above and dynamics model under the same initial condition.Simulation results demonstrate that the parametric model established by the proposed method shares a high consistency with the original dynamics model. | HU YuDong LI JunLong ZHANG Zhao JING WuXing GAO ChangSheng | 2020 | Science China(Technological Sciences)2020，63，8： | 3 |
| 5 | Tenofovir vs.entecavir on recurrence of hepatitis B virus-related hepatocellular carcinoma beyond Milan criteria after hepatectomy显示文摘Background:Hepatectomy for hepatocellular carcinoma(HCC)beyond the Milan criteria is shown to be beneficial.However,a high rate of post-operative HCC recurrence hinders the long-term survival of the patients.This study aimed to investigate and compare the impacts of tenofovir(TDF)and entecavir(ETV)on the recurrence of hepatitis B viral(HBV)-related HCC beyond the Milan criteria.Methods:Data pertaining to 1532 patients who underwent hepatectomy and received antiviral therapy between January 2014 and January 2019 were collected from five centers.Recurrence-free survival(RFS)analysis was performed using the Kaplan-Meier method.Cox proportional hazards regression analysis was performed to determine prognostic factors for HCC recurrence.Results:The analysis incorporates 595 HBV-related HCC patients.The overall 5-year RFS was 21.3%.Among them,533 and 62 patients received ETV and TDF treatment,respectively.The 1-,3-,and 5-year RFS rates were 46.3%,27.4%,and 19.6%,respectively,in the ETV group compared with 65.1%,41.8%,and 37.2%,respectively,in the TDF group(P<0.001).Multivariate analysis showed that TDF treatment(hazard ratio[HR]:0.604,P=0.005),cirrhosis(HR:1.557,P=0.004),tumor size(HR:1.037,P=0.008),microvascular invasion(MVI)(HR:1.403,P=0.002),portal vein tumor thrombus(PVTT)(HR:1.358,P=0.012),capsular invasion(HR:1.228,P=0.040),and creatinine levels(CREA)(HR:0.993,P=0.031)were statistically significant prognostic factors associated with RFS.Conclusions:Patients with HCC beyond the Milan criteria exhibited a high rate of HCC recurrence after hepatectomy.Compared to the ETV therapy,TDF administration significantly lowered the risk of HCC recurrence. | Junyi Shen Weili Qi Junlong Dai Shusheng Leng Kangyi Jiang Yu Zhang Shun Ran Chuan Li Tianfu Wen | 2022 | Chinese Medical Journal2022，，3： | 3 |
| 6 | Induced regulatory T cells suppress Tel cells through TGF-β signaling to ameliorate STZ-induced type 1 diabetes mellitus显示文摘Type 1 diabetes mellitus(T1D)is a chronic autoimmune condition in which the immune system destroys insulin-producing pancreatic β cells.In addition to well-established pathogenic effector T cells,regulatory T cells(Tregs)have also been shown to be defective in T1D.Thus,an increasing number of therapeutic approaches are being developed to target Tregs.However,the role and mechanisms of TGF-β-induced Tregs(iTregs)in T1D remain poorly understood.Here,using a streptozotocin(STZ)-induced preclinical T1D mouse model,we found that iTregs could ameliorate the development of T1D and preserve β cell function.The preventive effect was associated with the inhibition of type 1 cytotoxic T(Tel)cell function and rebalancing the Treg/Tc1 cell ratio in recipients.Furthermore,we showed that the underlying mechanisms were due to the TGF-β-mediated combinatorial actions of mTOR and TCF1.In addition to the preventive role,the therapeutic effects of iTregs on the established STZ-T1D and nonobese diabetic(NOD)mouse models were tested,which revealed improved β cell function.Our findings therefore provide key new insights into the basic mechanisms involved in the therapeutic role of iTregs in T1D. | Li Zhou Xuemin He Peihong Cai Ting Li Rongdong Peng Junlong Dang Yue Li Haicheng Li Feng Huang Guojun Shi Chichu Xie Yan Lu Yanming Chen | 2021 | Cellular & Molecular Immunology2021，18，3： | 3 |
| 7 | Report of epibenthic macrofauna found from Haima cold seeps and adjacent deep-sea habitats,South China Sea显示文摘This work reports on a preliminary taxonomic study of epibenthic macroinvertebrates collected or observed by underwater video at the Haima cold seeps and in adjacent deep-sea habitats,including a mud volcano feld and Ganquan Plateau,during an expedition in the South China Sea by the Chinese-manned submersible Shenhai Yongshi in May 2018.A total of 41 species belonging to 6 phyla were identifed,among which 34 species were collected from the Haima cold seeps.Mollusks and crustaceans that are specialized in reducing habitats were predominant in biotopes of the Haima cold seeps,whereas sponges and cold-water corals and their commensals were prominent in communities of the mud volcano feld and the slopes of Ganquan Plateau.The distribution and faunal composition of each taxonomic group are discussed. | Dong Dong Xinzheng Li Mei Yang Lin Gong Yang Li Jixing Sui Zhibin Gan Qi Kou Ning Xiao Junlong Zhang | 2021 | Marine Life Science & Technology2021，3，1： | 3 |
| 8 | A novel adaptive lateral reentry guidance algorithm with complex distributed no-fly zones constraints显示文摘Aimed at complex distributed no-fly zones avoidance problems,a novel adaptive lateral reentry guidance algorithm is proposed.Firstly,by introducing the improved attractive and repulsive potential fields,an improved artificial potential field method is developed.Combined with the proposed judgment criterion for whether a no-fly zone has been avoided,the proposed improved artificial potential field method effectively solves the reference heading angle determination problem under the constraints of complex distributed no-fly zones.Then,based on the proposed no-fly zone’s threat quantitative evaluation method and the reference heading angle determined by the proposed improved artificial potential field method,the heading corridor is improved to increase its sensitivity to the threat changes of the no-fly zones.Finally,for satisfying the requirements of complex distributed no-fly zones avoidance,a novel guidance logic via improved heading corridor is proposed to update the reference heading corridor adaptively in real time according to the threat and constraint changes of the no-fly zones,and the bank reversal logic is employed to control the lateral motion.The simulation results for nominal and dispersed cases indicate that the proposed guidance algorithm has high robustness,stability,and applicability,and is feasible and effective to deal with the complex distributed no-fly zones avoidance problems. | Yudong HU Changsheng GAO Junlong LI Wuxing JING Wenxue CHEN | 2022 | Chinese Journal of Aeronautics2022，35，7： | 2 |
| 9 | Edge-cloud Computing Systems for Smart Grid: State-of-the-art, Architecture, and Applications显示文摘The quantity and heterogeneity of intelligent energy generation and consumption terminals in the smart grid are increasing drastically over the years.These edge devices have created significant pressures on cloud computing(CC)system and centralised control for data storage and processing in realtime operation and control.The integration of edge computing(EC)can effectively alleviate the pressure and conduct real-time processing while ensuring data security.This paper conducts an extensive review of the EC-CC computing system and its application to the smart grid,which will integrate a vast number of dispersed devices.It first comprehensively describes the relationship among CC,fog computing(FC),and EC to provide a theoretical basis for the differentiation.It then introduces the architecture of the EC-CC computing system in the smart grid,where the architecture consists of both hardware structure and software platforms,and key technologies are introduced to support functionalities.Thereafter,the application to the smart grid is discussed across the whole supply chain,including energy generation,transportation(transmission and distribution networks),and consumption.Finally,future research opportunities and challenges of EC-CC while being applied to the smart grid are outlined.This paper can inform future research and industrial exploitations of these new technologies to enable a highly efficient smart grid under decarbonisation,digitalisation,and decentralisation transitions. | Junlong Li Chenghong Gu Yue Xiang Furong Li | 2022 | Journal of Modern Power Systems and Clean Energy2022，10，4： | 2 |
| 10 | Classification of estuaries in China based on eutrophication susceptibility to nutrient load显示文摘Recently, environmental pressures along coasts have increased substantially. Classification of estuaries according to their susceptibility to eutrophication nutrient load is a useful method to determine priority management objects and to enforce control measures. Using historical monitoring data from 2007 to 2012, from 65 estuaries, including 101 estuarine monitoring sections and 260 coastal monitoring stations, a nutrient-driven phytoplankton dynamic model was developed based on the relationship among phytoplankton biomass, Total Nitrogen(TN) load and physical features of estuaries. The ecological filter effect of estuaries was quantified by introducing conversion efficiency parameter values into the model. Markov Chain Monte Carlo algorithm of Bayesian inference was then employed to estimate parameters in the model. The developed model fitted well to the observed chlorophyll, primary production, grazing, and sinking rates. The analysis suggests that an estuary with Q/V(the ratio of river flow to estuarine volume) greater than 2.0 per year and ε(conversion efficiency ratio) less than 1.0 g C/g N can be classified as less susceptible to TN load, Q/V between 0.7 to 2.0 per year and ε between 1.0 to 3.0 g C/g N as moderately susceptible, and ε greater than 3.0 g C/g N as very susceptible. The estuaries with Q/V less than 0.7 per year vary greatly in their susceptibility. The estuaries with high and moderate susceptibility accounted for 67% of all the analyzed estuaries. They have relatively high eutrophication risks and should be the focus of environmental supervision and pollution prevention. | LI JunLong ZHENG BingHui LIU Yong WU Zhen LIU Fang SHAO JunBo HU XuPeng | 2015 | Science China Earth Sciences2015，58，6： | 2 |
| 11 | Small-molecule fluorescent probes for the detection of carbon dioxide显示文摘During the last few years, the preparation of novel fluorescent probes for the detection of carbon dioxide has attracted considerable attention since carbon dioxide plays extremely important roles in widespread fields including chemical, environmental, clinical analysis, and agri-food industry. This review focuses on the recent advances in the design principles, recognition mechanisms, and preparation of small-molecule fluorescent probes for the selective detection and monitoring of CO_2. Moreover, their properties and functions will be discussed detailedly as well. | Junlong Zhu Peipei Jia Nuo Li Shaoying Tan Junhai Huang Lin Xu | 2018 | Chinese Chemical Letters2018，29，10： | 2 |
| 12 | Surface Rupture and Coseismic Displacement of the M_S7.1 Yushu Earthquake显示文摘On April 14,2010,a devastating earthquake measured 7.1 on the Richter scale struck Yushu county,Qinghai Province,China.Field geological investigation and remote sensing interpretation show that this earthquake generated an inverse 'L-shaped' surface rupture zone,approximately 50km long.The surface rupture zone can be divided into three segments.Between the northern and middle segments of the surface rupture,there is a 16km-long segment,where no rupture was observed.The middle and the southern segments are arranged in a left-step manner,and there are right-step en echelon ruptures developed in the stepovers.The seismogenic structure is the Yushu fault,which is dominated by strike-slip with a small amount of thrust component.The earthquake results from the differential movements between the southern Qiangtang Block and northern Bayan Har Block.The earthquake recurrence interval is 185a^108a.Along an approximately 20km-long part of the Garzê-Yushu fault,between the southern surface rupture of Yushu MS7.1 earthquake and the 1896 earthquake,there is no surface rupture,its seismic risk needs further research. | Zhang Junlong Chen Changyun Hu Chaozhong Yang Panxin Xiong Renwei Li Zhimin Ren Jinwei | 2011 | Earthquake Research in China2011，25，2： | 2 |
| 13 | A Preliminary Study on a Seismotectonic Model for the Active Faults in the Xining Urban Area显示文摘On the basis of the Xining active urban fault survey,we studied the relationship between the active urban fault and fold deformation.The result of this research shows that the Huangshuihe fault and the NW-striking fault on the northern bank of the Huangshuihe River are tensional faults on top of an anticline,the Nanchuanhe fault is a transverse tear fault resulting from differential folding on two sides of the fault,the east bank of the Beichuanhe River fault is a compressional fault developed on the core or climb of a syncline.By balance profile analysis of fold deformation and inversion of gravity anomaly data,we obtained the depth of the detachment plane and established the seismotectonic model of the Xining urban area.Based on the seismotectonic model,we analyzed the earthquake potential of the active urban fault. | Tian Qinjian Li Zhimin Zhang Junlong Ren Zhikun | 2008 | Earthquake Research in China2008，22，1： | 2 |
| 14 | Survey and analysis of energy consumption in office buildings in Tianjin显示文摘 | Junlong LI Huan ZHANG Shijun YOU Zhenhui XIE | 2013 | Frontiers in Energy2013，7，1： | 2 |
| 15 | Fabrication of paper-based devices for in vitro tissue modeling显示文摘Paper devices have recently attracted considerable attention as a class of cost-effective cell culture substrates for various biomedical applications.The paper biomaterial can be used to partially mimic the in vivo cell microenvironments mainly due to its natural three-dimensional characteristic.The paper-based devices provide precise control over their structures as well as cell distributions,allowing recapitulation of certain interactions between the cells and the extracellular matrix.These features have shown great potential for the development of normal and diseased human tissue models.In this review,we discuss the fabrication of paper-based devices for in vitro tissue modeling,as well as the applications of these devices toward drug screening and personalized medicine.It is believed that paper as a biomaterial will play an essential role in the field of tissue model engineering due to its unique performances,such as good biocompatibility,eco-friendliness,cost-effectiveness,and amenability to various biodesign and manufacturing needs. | Hongbin Li Feng Cheng Juan A.Robledo-Lara Junlong Liao Zixuan Wang Yu Shrike Zhang | 2020 | Bio-Design and Manufacturing2020，3，3： | 1 |
| 16 | Output formation tracking for networked systems with limited energy and aperiodic silence显示文摘For leader-following networked systems with the topology switching and the aperiodic silence,limited-energy output formation tracking problems are investigated.Firstly,a new output formation tracking control protocol is proposed,which contains two components associated with the communication interactions between the leader and tracking intelligent agents and the communication interactions among tracking intelligent agents,respectively,and the aperiodic silence,the topology switching and the energy constraint index is introduced properly.Then,a two-step transformation method is presented to separate the whole dynamics of a networked system into the relative dynamics between the leader and tracking intelligent agents and the dynamics of the leader,and sufficient conditions for limited-energy output formation tracking for networked systems with limited energy and aperiodic silence are presented,which are extended into networked systems without the aperiodic silence.Especially,a partition checking algorithm is presented to check limitedenergy output formation tracking design criteria.Finally,a numerical example is illustrated to demonstrate the validness of theoretical results. | Jin JIN Junlong LI Donghao QIN Ning CAI | 2022 | Chinese Journal of Aeronautics2022，35，7： | 1 |
| 17 | Loop-mediated isothermal amplification (LAMP) method based on two species-specific primer sets for the rapid identification of Chinese Babesia bovis and B. bigemina显示文摘 | Aihong Liu Guiquan Guan Pengfei Du Huitian Gou Zhijie Liu Junlong Liu Milin Ma Jifei Yang Youquan Li Qinli Niu Qiaoyun Ren Qi Bai Hong Yin Jianxun Luo | 2012 | Parasitology International2012，，4： | 1 |
| 18 | The cooperative relation between non‐hydraulic root signals and osmotic adjustment under water stress improves grain formation for spring wheat varieties显示文摘 | Xian‐WeiFan Feng‐MinLi You‐CaiXiong Li‐ZheAn Rui‐JunLong | 2007 | Physiologia Plantarum2007，，3： | 1 |
| 19 | A VO x /meso-TiO 2 catalyst for methanol oxidation to dimethoxymethane显示文摘 | Ensheng Zhan Yong Li Junlong Liu Xiumin Huang Wenjie Shen | 2009 | Catalysis Communications2009，，15： | 1 |
| 20 | Detecting and differentiating Theileria sergenti and Theileria sinensis in cattle and yaks by PCR based on major piroplasm surface protein (MPSP)显示文摘 | Aihong Liu Guiquan Guan Zhijie Liu Junlong Liu Neil Leblanc Youquan Li Jinliang Gao Milin Ma Qinli Niu Qiaoyun Ren Qi Bai Hong Yin Jianxun Luo | 2010 | Experimental Parasitology2010，，4： | 1 |
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