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1Myeloid-specific targeting of Notch ameliorates murine renal fibrosis via reduced infiltration and activation of bone marrowderived macrophage显示文摘Macrophages play critical roles in renal fibrosis.However,macrophages exhibit ontogenic and functional heterogeneities,and which population of macrophages contributes to renal fibrosis and the underlying mechanisms remain unclear.In this study,we genetically targeted Notch signaling by disrupting the transcription factor recombination signal binding protein-JK(RBP-J),to reveal its role in regulation of macrophages during the unilateral ureteral obstruction(UUO)-induced murine renal fibrosis.Myeloid-specific disruption of RBP-J attenuated renal fibrosis with reduced extracellular matrix deposition and myofibroblast activation,as well as attenuated epithelial-mesenchymal transition,likely owing to the reduced expression of TGF-β.Mean while,RBP-J deletion significantly hampered macrophage infiltration and activation in fibrotic kidney,although their proliferation appeared unaltered.By using macrophage clearance experiment,we found that kidney resident macrophages made negligible contribution,but bone marrow(BM)-derived macrophages played a major role in renal fibrogenesis.Further mechanistic analyses showed that Notch blockade reduced monocyte emigration from BM by down-regulating CCR2 expression.Finally,we found that myeloid-specific Notch activation aggravated renal fibrosis,which was mediated by CCR2^+macrophages infiltration.In summary,our data have unveiled that myeloid-specific targeting of Notch could ameliorate renal fibrosis by regulating BM-derived macrophages recruitment and activation,providing a novel strategy for intervention of this disease.Yali Jiang Yuanyuan Wang Pengfei Ma Dongjie An Junlong Zhao Shiqian Liang Yuchen Ye Yingying Lu Peng Zhang Xiaowei Liu Hua Han Hongyan Qin 2019Protein & Cell2019,10,3:10
2The Late Pleistocene activity of the eastern part of east Kunlun fault zone and its tectonic significance显示文摘The nearly EW-trending East Kunlun fault zone is the north boundary of the Bayan Har block.The activity characteristics and the position of the eastern end of its eastward extension are of great significance to probing into the dynamic mechanism of formation of the east edge of the Tibetan Plateau,and also lay the foundation for seismic risk assessment of the fault zone.The following results are obtained by analysis based on satellite image interpretation of landforms,surface rupture survey,terrace scarp deformation survey,and terrace dating data on the eastern part of the East Kunlun fault zone:(1)the Luocha segment is a Holocene active fault,where a reverse L-shape paleoearthquake surface rupture zone of about 50 km long is located;(2)the Luocha segment is characterized by left-lateral slip movement under the compression-shear condition since the later period of the Late Pleistocene,with a rate of 7.68–9.37 mm/a and a vertical slip rate of 0.7–0.9 mm/a,which are basically in accord with the activity rate of segments on its west side.The results indicate that it is a part of eastward extension of the East Kunlun fault zone;(3)the high-speed linear horizontal slip of the nearly EW-trending East Kunlun fault zone is blocked by the South China block at east,and transforms into the vertical movement of the nearly SN-NNE trending Minjiang fault zone and the Longmenshan fault zone,and the uplift of Longmenshan and Minjiang.The area where transform of the two tectonic systems occurred confines the position of the east end;(4)Luocha segment and Maqu segment constitute the'Maqu seismic gap',so,seismic risk at Maqu segment is higher than that at Luocha segment,which should attract more attention.ZHANG JunLong REN JinWei CHEN ChangYun FU JunDong YANG PanXin XIONG RenWei HU ChaoZhong 2014Science China Earth Sciences2014,57,3:8
3Xuefuzhuyu injection induces neuronal differentiation of rat bone morrow mesenchymal stem cells显示文摘The primary effective components of Xuefuzhuyu,including Rhizoma Chqanxiong,Radix Salviae Miltiorrhiae,and Radix Angelicae Sinensis,have been shown to induce the differentiation of bone marrow mesenchymal stem cells(BMMSCs) into neuronal-like cells.However,there is little available evidence on the effects of the Chinese herbal compound Xuefuzhuyu on BMMSC differentiation.The present study investigated the effects of Xuefuzhuyu on differentiation of rat BMMSCs into neuronal-like cells,and evaluated the optimal concentration for inducing differentiation.Inverted microscopy was used to observe BMMSCs induced by Xuefuzhuyu;immunocytochemistry revealed expression of the neuronal marker neuron-specific enolase surface antigen in the majority of BMMSCs following treatment with Xuefuzhuyu at concentrations of 1,3,5,and 10 g/L.A concentration of 3 g/L resulted in highest neuron-specific enolase expression.These results suggest that BMMSCs can be induced to differentiate into neuronal-like cells with Xuefuzhuyu,and 3 g/L is the optimal inductive concentration for effective differentiation.Yin, Yanqing Chen, Bing Ke, Junlong Mo, Wei Zou, Xinhui Liang, Yuansheng 2011Neural Regeneration Research2011,6,3:6
4The radioactive abnormality characteristics of typical regions in Ordos Basin and its geological implications显示文摘There are many results of single mineral enrichment characteristic, such as oil, gas, coal and uranium, but little is known about the synergistic research of these important minerals and the study of uranium enrichment features in the deep basin. So, the study on the paragenesis regularity and coexisting relation of many minerals in the basin will promote the integrated forecast and cooperative exploitation of the basin. Based on the plentiful logging data and geological data, this paper studies the distributing feature of higher Gamma abnormality. The analysis on 33 core samples' test results indicates that the increasing of Gamma abnormality is due to the increasing of the uranium element, and the enrichment of uranium is a result of the activation and conglomeration of uranium. On the basis of the recognization of radioactive abnormality and the study about the reality of oil,gas,coal or uranium coexisting in a basin and its mechanism, the paper shows that there is a certain mutual promotion in oil, gas, coal and uranium in the basin, which provides an important theory basis for cooperative exploitation of energy resources.TAN ChengQian LIU ChiYang ZHAO JunLong ZHANG RongRong 2007Science China Earth Sciences2007,50,z2:6
5食管扩张——一种胃食管反流触发机制显示文摘目的 :明确食管扩张时下食管括约肌发生松弛状态下胃食管反流的发生率。方法 :12例健康志愿者在餐前和餐后同时检测食管压力和 pH ,食管扩张是通过快速和缓慢的气体注射诱发。 结果 :引起完全的下食管扩约肌松弛的气体阈值量平均为 (11 0± 1 0 )ml。只有极少的松弛伴有继发蠕动。快速注气下食管括约肌的松弛时间为(13.0± 1.5 )s;慢速注射时食管括约肌的松弛时间是 (16 0± 2 0 )s。由快速阈值量气体注射引起LES松弛并伴有胃食管反流率 ,在餐后为 (2 2± 6 ) % ;缓慢注射时为 (2 3± 10 ) %。对于快速食管扩张 ,单独的下食管括约肌松弛伴随反流的百分比显著高于伴有继发蠕动的下食管括约肌松弛时出现的胃食管反流情况。结论 :(1)胃食管反流可以发生在由食管扩张引起的下食管括约肌松弛期内 ;(2 )食管扩张可以引起不伴随继发蠕动的单纯下食管括约肌松弛 ;(3)单纯下食管括约肌松弛时的胃食管反流发生率显著高于伴有继发蠕动的情况。谢鹏雁 Eytan Bardan Junlong Ren Walter J Hogan Reza Shaker 2000北京医科大学学报2000,32,2:5
6Vaccination against Schistosoma japonicum Infection by DNA Vaccine Encoding Sj22.7 Antigen显示文摘在鼠标的效果, recombinant 原生质标志 pcDNA3-Sj22.7 与调停 liposome 的方法习惯于 transfectHeLa 房间, Sj22.7 mRNA 和蛋白质的表达式用反向的抄写聚合酶链反应,钠 dodecylsulfate-polyacrylamide 凝胶电泳和蛋白质印迹被检验。然后, pcDNA3-Sj22.7 的能力在鼠标的种痘以后根据蠕虫减小率和鸡蛋减小率被分析免于 Schistosomajaponicum 挑战感染。特定的 IgG 抗体和 T 淋巴细胞增长反应的浆液层次也是坚定的。在挑战感染以后,驾驶 Sj22.7 的干扰素(IFN )-gamma andinterleukin (IL )-4 也被确定。结果证明 pcDNA3-Sj22.7 能表示 Sj22.7 mRNAand 在 vitro.Immunization 的蛋白质导致了29.70%的蠕虫减小率;鸡蛋减小率of47.25%(肝)并且51.73%(肠),并且25.90%的鸡蛋减小率(鸡蛋每女性),在 连接group.Enzyme 的免疫吸着剂试金和蛋白质印迹分析显示了的 pcDNA3-Sj22.7 建议重要反肥沃的正式就职那使对从与 pcDNA3-Sj22.7 使免疫的鼠标的 Sj22.7.Tlymphocytes 的产生特定的 IgG 显示出的鼠标免疫怒气房间的一种重要增长反应 torSj22.7.The 文化证明 IFN-gamma 的那分泌物增加了但是 IL-4decreased.The 结果显示由 pcDNA3-Sj22.7 的 DNA 种痘对足够对 S.japonicum 感染得到保护的免疫的重要层次。DNA 疫苗能导致重要细胞、体液的有免疫力的反应,并且显示占优势的 T 助手房间类型 1 类型免疫者回答,它在鼠标对挑战感染贡献保护的免疫。Gan DAI Shiping WANG Junlong YU Shaorui XU Xianchu PENG Zhuo HE Xueqin LIU Songhua ZHOU and Fen LIU Institute of Schistosomiasis Research.Xiangya School of Medicine,Central South University,Changsha 410078 China 2007Acta Biochimica et Biophysica Sinica2007,39,1:5
7Terrestrial input and nutrient change reflected by sediment records of the Changjiang River Estuary in recent 80 years显示文摘A variety of environmental problems have been observed in the Changjiang River Estuary and adjacent coastal area, including eutrophication, harmful algal blooms(HABs), and hypoxia in recent decades. Application of sedimentary biogenic element indicators on the study of paleoenvironment can reconstruct environmental evolution history of waters. Two 210Pb-dated cores were collected from the Changjiang River Estuary(S3) and adjacent coastal area(Z13), and total organic carbon(TOC), total nitrogen(TN), biogenic silicon(BSi), total phosphorus(TP) and phosphorus(P) species were analyzed. Three stages of environmental changes are deduced by the nutrient sedimentary records. First, nutrient concentration increased rapidly since the 1950 s, which attributed to agriculture development and overused chemical fertilizers. Second, nutrient concentration kept high and primary production began to promote during the 1960 s to 1980 s, while diatom abundance and proportion began to decline since the 1970 s, accompanied by reduced 23 Si O- concentration and flux from the river. Third, due to several dams and bridges constructed, river runoff and coastal hydrodynamic conditions reduced to a certain extent since the 1990 s, which aggravated the unbalance in nutrient structure. Multi-nutrient proxies in sediment can reflect the natural environm-ental changes as well as influence of human activities.LI Junlong ZHENG Binghui HU Xupeng WANG Yiming DING Ye LIU Fang 2015Acta Oceanologica Sinica2015,34,2:4
8A New Method of Thermal Protection by Opposing Jet for a Hypersonic Aeroheating Strut显示文摘This paper presents the numerical investigation of thermal protection of scramjet strut by opposing jet in supersonic stream of Mach number 6 with a hydrogen fueled scramjet strut model using CFD software. Simulation results indicate that when a small amount of fuel is injected from the nose of the strut, the bow shock is pushed away from the strut, and the heat flux is reduced in the strut, especially at the leading edge. Opposing jet forms a recirculation region near the nozzle so that the strut is covered with low temperature fuel and separated from free stream. An appropriate total pressure ratio can be used to reduce not only aerodynamic heating but also the drag of strut. It is therefore concluded that thermal protection of scramjet strut by opposing jet is one of the promising ways to protect scramjet strut in high enthalpy stream.QIN Jiang NING Dongpo FENG Yu ZHANG Junlong FENG Shuo BAO Wen 2017Journal of Thermal Science2017,26,3:4
9Cloning, expression and protective immunity evalua-tion of the full-length cDNA encoding succinate dehydrogenase iron-sulfur protein of Schistosoma japonicum显示文摘1071-bp fragment was obtained from the Schistosoma japonicum (Chinese strain) adult cDNA library after the 3′ and 5′ ends of the incomplete expression sequence tag (EST) of succinate dehydrogenase iron-sulfur protein of Schistosoma japonicum (SjSDISP) were amplified by the anchored PCR with 2 pairs of primers designed according to the EST of SjSDISP and the sequence of multiclone sites of the library vector. Sequence analysis indicated that the fragment was a full-length cDNA with a complete open reading frame (ORF), encoding 278 amino acid residues. The fragment was cloned into prokary- otic expression vector pQE30, and subsequently sequenced and expressed in Escherichia coli. SDS-PAGE and Western-blot analyses showed that the recombinant protein was about 32 kD and could be recognized by the polyclonal antisera from rabbits immunized with Schistosoma japonicum adult worm antigen. Compared with the FCA controls, mice vaccinated with rSjSDISP (test) or rSjGST (posi- tive control) all revealed high levels of specific antibody and significant reduction in worm burden, liver eggs per gram (LEPG), fecal eggs per gram (FEPG) and intrauterine eggs. These results suggest that SjSDISP may be a novel and partially protective vaccine candidate against schistosomiasis. In contrast to the worm burden reduction rate, the higher degree of egg reduction rate in the test group also sug- gested that SjSDISP vaccine may primarily play a role in anti-embryonation or anti-fecundity immunity.YU JunLong, WANG ShiPing, LI WenKai, DAI Gan, XU ShaoRui, HE Zhuo, PENG XianChu, ZHOU SongHua & LIU XueQin Department of Parasitology, Xiangya School of Medicine, Central South University, Changsha 410078, China 2007Science China(Life Sciences)2007,50,2:4
10Mission-oriented dynamic optimization model of carrying spares for warship redundant system显示文摘Redundancy is a common structure for warship system,and it is an effective way to improve the reliability of the system.In this paper, warship system is taken as the object of study,based on the system reliability equivalence principle, a spares demand rate calculation method for redundant system is proposed through structure transformation. According to the system analysis method, the general modeling data structure of spares support echelon and system indenture is established, and the mission success probability is taken as the optimization target to build the dynamic optimization model of carrying spares during the process of multi-phase. By introducing the Lagrange multiplier, the spares weight, volume and cost are transformed to the single target of the spares total scale, and the initial Lagrange factors and its dynamic adjustment policy is proposed. In a given example, the main influence factors of the carrying spares project are analyzed, and the study results are in accordance with the reality, which can provide a new approach to mission-oriented carrying spares optimization for the redundant system.RUAN Minzhi LI Hua WANG Junlong 2018Journal of Systems Engineering and Electronics2018,29,3:4
11Parametric modeling of hypersonic ballistic data based on time varying auto-regressive model显示文摘For describing target motion in hypersonic vehicle defense,a parametric analyzing and modeling method on ballistic data is proposed based on time varying auto-regressive method.Ballistic data are regarded as non-stationary random signal,where the hidden internal law is studied.Firstly,ballistic data are decomposed into smooth linear trend signal and non-stationary periodic skip signal with ensemble empirical mode decomposition method to avoid mutual interference between different modal data.Secondly,the linear trend signal and the periodic skip signal are modeled separately.The linear trend signal is approximated by power function regressive estimator and the periodic skip signal is modeled based on time varying auto-regressive method.In order to determine optimal model orders,a novel method is presented based on information theoretic criteria and the criteria of minimizing the mean absolute error.Finally,the consistency test is conducted by investigating the time-frequency spectrum characteristics and statistical properties of outputs of the parametric model established above and dynamics model under the same initial condition.Simulation results demonstrate that the parametric model established by the proposed method shares a high consistency with the original dynamics model.HU YuDong LI JunLong ZHANG Zhao JING WuXing GAO ChangSheng 2020Science China(Technological Sciences)2020,63,8:3
12Tenofovir vs.entecavir on recurrence of hepatitis B virus-related hepatocellular carcinoma beyond Milan criteria after hepatectomy显示文摘Background:Hepatectomy for hepatocellular carcinoma(HCC)beyond the Milan criteria is shown to be beneficial.However,a high rate of post-operative HCC recurrence hinders the long-term survival of the patients.This study aimed to investigate and compare the impacts of tenofovir(TDF)and entecavir(ETV)on the recurrence of hepatitis B viral(HBV)-related HCC beyond the Milan criteria.Methods:Data pertaining to 1532 patients who underwent hepatectomy and received antiviral therapy between January 2014 and January 2019 were collected from five centers.Recurrence-free survival(RFS)analysis was performed using the Kaplan-Meier method.Cox proportional hazards regression analysis was performed to determine prognostic factors for HCC recurrence.Results:The analysis incorporates 595 HBV-related HCC patients.The overall 5-year RFS was 21.3%.Among them,533 and 62 patients received ETV and TDF treatment,respectively.The 1-,3-,and 5-year RFS rates were 46.3%,27.4%,and 19.6%,respectively,in the ETV group compared with 65.1%,41.8%,and 37.2%,respectively,in the TDF group(P<0.001).Multivariate analysis showed that TDF treatment(hazard ratio[HR]:0.604,P=0.005),cirrhosis(HR:1.557,P=0.004),tumor size(HR:1.037,P=0.008),microvascular invasion(MVI)(HR:1.403,P=0.002),portal vein tumor thrombus(PVTT)(HR:1.358,P=0.012),capsular invasion(HR:1.228,P=0.040),and creatinine levels(CREA)(HR:0.993,P=0.031)were statistically significant prognostic factors associated with RFS.Conclusions:Patients with HCC beyond the Milan criteria exhibited a high rate of HCC recurrence after hepatectomy.Compared to the ETV therapy,TDF administration significantly lowered the risk of HCC recurrence.Junyi Shen Weili Qi Junlong Dai Shusheng Leng Kangyi Jiang Yu Zhang Shun Ran Chuan Li Tianfu Wen 2022Chinese Medical Journal2022,,3:3
13Performance of overlapped shield tunneling through an integrated physical model tests,numerical simulations and real-time field monitoring显示文摘In this work,deformations and internal forces of an existing tunnel subjected to a closely overlapped shield tunneling are monitored and analyzed using a series of physical model experiments and numerical simulations.Effects of different excavation sequences and speeds are explicitly considered in the analysis.The results of the physical model experiments show that the bottom-up tunneling procedure is better than the top-down tunneling procedure.The incurred deformations and internal forces of the existing tunnel increase with the excavation speed and the range of influence areas also increase accordingly.For construction process control,real-time monitoring of the power tunnel is used.The monitoring processes feature full automation,adjustable frequency,real-time monitor and dynamic feedback,which are used to guide the construction to achieve micro-disturbance control.In accordance with the situation of crossing construction,a numerical study on the performance of power tunnel is carried out.Construction control measures are given for the undercrossing construction,which helps to accomplish the desired result and meet protection requirements of the existing tunnel structure.Finally,monitoring data and numerical results are compared,and the displacement and joint fracture change models in the power tunnel subject to the overlapped shield tunnel construction are analyzed.Junlong Yang Chen Liu Qiushi Chen Xiongyao Xie 2017Underground Space2017,2,1:3
14Structural variation during dog domestication: insights from gray wolf and dhole genomes显示文摘Several processes like phenotypic evolution, disease susceptibility and environmental adaptations, which fashion the domestication of animals, are largely attributable to structural variations(SVs) in the genome.Here, we present high-quality draft genomes of the gray wolf(Canis lupus) and dhole(Cuon alpinus) with scaffold N50 of 6.04 Mb and 3.96 Mb, respectively. Sequence alignment comprising genomes of three canid species reveals SVs specific to the dog, particularly 16 315 insertions, 2565 deletions, 443 repeats, 16 inversions and 15 translocations. Functional annotation of the dog SVs associated with genes indicates their enrichments in energy metabolisms, neurological processes and immune systems. Interestingly, we identify and verify at population level an insertion fully covering a copy of the AKR1 B1(Aldo-Keto Reductase Family 1 Member B) transcript. Transcriptome analysis reveals a high level of expression of the new AKR1 B1 copy in the small intestine and liver, implying an increase in de novo fatty acid synthesis and antioxidant ability in dog compared to gray wolf, likely in response to dietary shifts during the agricultural revolution. For the first time, we report a comprehensive analysis of the evolutionary dynamics of SVs during the domestication step of dogs. Our findings demonstrate that retroposition can birth new genes to facilitate domestication, and affirm the importance of large-scale genomic variants in domestication studies.Guo-Dong Wang Xiu-Juan Shao Bing Bai Junlong Wang Xiaobo Wang Xue Cao Yan-Hu Liu Xuan Wang Ting-Ting Yin Shao-Jie Zhang Yan Lu Zechong Wang Lu Wang Wenming Zhao Bing Zhang Jue Ruan Ya-Ping Zhang 2019National Science Review2019,6,1:3
15Certificateless Public Verification for Data Storage and Sharing in the Cloud显示文摘By advances in cloud computing,users are allowed to remotely store their data in the cloud,manage the stored data without limitation of time and place,and give rights to visitors that want to access to their data.As may no longer possess data physically,the data owner has to ensure the integrity of the data with the public key given by Public key infrastructure(PKI).However,there are many security risks of the traditional PKI and the certificate management is complex.We utilize elliptic curve group to propose a certificateless signature to solve the above problem.To check the integrity of files stored in the cloud,we design a certificateless public verification mechanism based on the signature and further extend it to support batch auditing tasks.Meanwhile,an efficient key updating method is proposed to provide visitors a friendly data success environment.The security analysis proves that the proposed scheme is secure under the discrete logarithm assumption.Extensive theoretical analyses and experimental results show the effectiveness of the proposed scheme.HUANG Longxia ZHOU Junlong ZHANG Gongxuan ZHANG Mingyue 2020Chinese Journal of Electronics2020,29,4:3
16Induced regulatory T cells suppress Tel cells through TGF-β signaling to ameliorate STZ-induced type 1 diabetes mellitus显示文摘Type 1 diabetes mellitus(T1D)is a chronic autoimmune condition in which the immune system destroys insulin-producing pancreatic β cells.In addition to well-established pathogenic effector T cells,regulatory T cells(Tregs)have also been shown to be defective in T1D.Thus,an increasing number of therapeutic approaches are being developed to target Tregs.However,the role and mechanisms of TGF-β-induced Tregs(iTregs)in T1D remain poorly understood.Here,using a streptozotocin(STZ)-induced preclinical T1D mouse model,we found that iTregs could ameliorate the development of T1D and preserve β cell function.The preventive effect was associated with the inhibition of type 1 cytotoxic T(Tel)cell function and rebalancing the Treg/Tc1 cell ratio in recipients.Furthermore,we showed that the underlying mechanisms were due to the TGF-β-mediated combinatorial actions of mTOR and TCF1.In addition to the preventive role,the therapeutic effects of iTregs on the established STZ-T1D and nonobese diabetic(NOD)mouse models were tested,which revealed improved β cell function.Our findings therefore provide key new insights into the basic mechanisms involved in the therapeutic role of iTregs in T1D.Li Zhou Xuemin He Peihong Cai Ting Li Rongdong Peng Junlong Dang Yue Li Haicheng Li Feng Huang Guojun Shi Chichu Xie Yan Lu Yanming Chen 2021Cellular & Molecular Immunology2021,18,3:3
17Report of epibenthic macrofauna found from Haima cold seeps and adjacent deep-sea habitats,South China Sea显示文摘This work reports on a preliminary taxonomic study of epibenthic macroinvertebrates collected or observed by underwater video at the Haima cold seeps and in adjacent deep-sea habitats,including a mud volcano feld and Ganquan Plateau,during an expedition in the South China Sea by the Chinese-manned submersible Shenhai Yongshi in May 2018.A total of 41 species belonging to 6 phyla were identifed,among which 34 species were collected from the Haima cold seeps.Mollusks and crustaceans that are specialized in reducing habitats were predominant in biotopes of the Haima cold seeps,whereas sponges and cold-water corals and their commensals were prominent in communities of the mud volcano feld and the slopes of Ganquan Plateau.The distribution and faunal composition of each taxonomic group are discussed.Dong Dong Xinzheng Li Mei Yang Lin Gong Yang Li Jixing Sui Zhibin Gan Qi Kou Ning Xiao Junlong Zhang 2021Marine Life Science & Technology2021,3,1:3
18Preseismic deformation associated with the 2014 Ms7.3 Yutian earthquake derived from GPS data显示文摘Based on analysis of the GPS data during 1999-2007,2009-2011,and 2011-2013 mainly from the Crustal Motion Observation Network of China,we obtained the GPS horizontal velocity field,the GPS strain rate field,and the profiles across the southwestern segment of the Altyn Tagh Fault zone and its adjacent regions and identified the different characteristics of horizontal crustal deformation fields and profiles during different periods. The results show that,before the February 12,2014,Ms7. 3 Yutian earthquake,the laevorotation deformation along the southwestern segment of the Altyn Tagh Fault zone increased about 3. 3 mm /a during 2011-2013,relative to that in 2009-2011,and the GPS strain rate field distributed in the southeastern segment of the Altyn Tagh Fault during 2011-2013 increased obviously. These abnormal changes may be regarded as precursors to the Ms7. 3 Yutian earthquake.Chen Changyun Chen Fuchao Zheng Zhijiang Zhu Shuang Zhang Junlong Yang Panxin 2014Geodesy and Geodynamics2014,5,2:3
19A novel adaptive lateral reentry guidance algorithm with complex distributed no-fly zones constraints显示文摘Aimed at complex distributed no-fly zones avoidance problems,a novel adaptive lateral reentry guidance algorithm is proposed.Firstly,by introducing the improved attractive and repulsive potential fields,an improved artificial potential field method is developed.Combined with the proposed judgment criterion for whether a no-fly zone has been avoided,the proposed improved artificial potential field method effectively solves the reference heading angle determination problem under the constraints of complex distributed no-fly zones.Then,based on the proposed no-fly zone’s threat quantitative evaluation method and the reference heading angle determined by the proposed improved artificial potential field method,the heading corridor is improved to increase its sensitivity to the threat changes of the no-fly zones.Finally,for satisfying the requirements of complex distributed no-fly zones avoidance,a novel guidance logic via improved heading corridor is proposed to update the reference heading corridor adaptively in real time according to the threat and constraint changes of the no-fly zones,and the bank reversal logic is employed to control the lateral motion.The simulation results for nominal and dispersed cases indicate that the proposed guidance algorithm has high robustness,stability,and applicability,and is feasible and effective to deal with the complex distributed no-fly zones avoidance problems.Yudong HU Changsheng GAO Junlong LI Wuxing JING Wenxue CHEN 2022Chinese Journal of Aeronautics2022,35,7:2
20Edge-cloud Computing Systems for Smart Grid: State-of-the-art, Architecture, and Applications显示文摘The quantity and heterogeneity of intelligent energy generation and consumption terminals in the smart grid are increasing drastically over the years.These edge devices have created significant pressures on cloud computing(CC)system and centralised control for data storage and processing in realtime operation and control.The integration of edge computing(EC)can effectively alleviate the pressure and conduct real-time processing while ensuring data security.This paper conducts an extensive review of the EC-CC computing system and its application to the smart grid,which will integrate a vast number of dispersed devices.It first comprehensively describes the relationship among CC,fog computing(FC),and EC to provide a theoretical basis for the differentiation.It then introduces the architecture of the EC-CC computing system in the smart grid,where the architecture consists of both hardware structure and software platforms,and key technologies are introduced to support functionalities.Thereafter,the application to the smart grid is discussed across the whole supply chain,including energy generation,transportation(transmission and distribution networks),and consumption.Finally,future research opportunities and challenges of EC-CC while being applied to the smart grid are outlined.This paper can inform future research and industrial exploitations of these new technologies to enable a highly efficient smart grid under decarbonisation,digitalisation,and decentralisation transitions.Junlong Li Chenghong Gu Yue Xiang Furong Li 2022Journal of Modern Power Systems and Clean Energy2022,10,4:2
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