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73篇 您的检索式:作者名="LI HongDa"
    题名 作者 年代 出处 被引量
1A low-complexity ECG processing algorithm based on the Haar wavelet transform for portable health-care devices显示文摘This paper presents a simple Electrocardiogram(ECG)processing algorithm for portable healthcare devices.This algorithm consists of the Haar wavelet transform(HWT),the modulus maxima pair detection(MMPD)and the peak position modification(PPM).To lessen the computational complexity,a novel no multiplier structure is introduced to implement HWT.In the MMPD,the HWT coefficient at scale 24is processed to find candidate peak positions of ECG.The PPM is designed to correct the time shift in digital process and accurately determine the location of peaks.Some new methods are proposed to improve anti-jamming performance in MMPD and PPM.Evaluated by the MIT-BIH arrhythmia database,the sensitivity(Se)of QRS detection is 99.53%and the positive prediction(Pr)of QRS detection is 99.70%.The QT database is chosen to fully validate this algorithm in complete delineation of ECG waveform.The meanμand standard deviationσbetween test results and annotations are calculated.Most ofσsatisfies the CSE limits which indicates that the results are stable and reliable.A detailed and rigorous computational complexity analysis is presented in this paper.The number of arithmetic operations in N input samples is chosen as the criterion of complexity.Without any multiplication operations,the number of addition operations is only about 16.33N.This algorithm achieves high detection accuracy and the lower computational complexity.LI Peng LIU Ming ZHANG Xu CHEN HongDa 2014Science China(Information Sciences)2014,57,12:13
2Offline two-dimensional liquid chromatography coupled with ion mobility-quadrupole time-of-flight mass spectrometry enabling fourdimensional separation and characterization of the multicomponents from white ginseng and red ginseng显示文摘Inherent complexity of plant metabolites necessitates the use of multi-dimensional information to accomplish comprehensive profiling and confirmative identification.A dimension-enhanced strategy,by offline two-dimensional liquid chromatography/ion mobility-quadrupole time-of-flight mass spectrometry(2 D-LC/IM-QTOF-MS)enabling four-dimensional separations(2 D-LC,IM,and MS),is proposed.In combination with in-house database-driven automated peak annotation,this strategy was utilized to characterize ginsenosides simultaneously from white ginseng(WG)and red ginseng(RG).An offline 2 DLC system configuring an Xbridge Amide column and an HSS T3 column showed orthogonality 0.76 in the resolution of ginsenosides.Ginsenoside analysis was performed by data-independent high-definition MSE(HDMSE)in the negative ESI mode on a Vion?IMS-QTOF hybrid high-resolution mass spectrometer,which could better resolve ginsenosides than MSEand directly give the CCS information.An in-house ginsenoside database recording 504 known ginsenosides and 58 reference compounds,was established to assist the identification of ginsenosides.Streamlined workflows,by applying UNIFI?to automatedly annotate the HDMSEdata,were proposed.We could separate and characterize 323 ginsenosides(including 286 from WG and 306 from RG),and 125 thereof may have not been isolated from the Panax genus.The established 2 D-LC/IM-QTOF-HDMSEapproach could also act as a magnifier to probe differentiated components between WG and RG.Compared with conventional approaches,this dimensionenhanced strategy could better resolve coeluting herbal components and more efficiently,more reliably identify the multicomponents,which,we believe,offers more possibilities for the systematic exposure and confirmative identification of plant metabolites.Tiantian Zuo Chunxia Zhang Weiwei Li Hongda Wang Ying Hu Wenzhi Yang Li Jia Xiaoyan Wang Xiumei Gao Dean Guo 2020Journal of Pharmaceutical Analysis2020,10,6:9
3A flexible capacitive tactile sensor array with micro structure for robotic application显示文摘A flexible capacitive tactile sensor array with micro needle structure is proposed in this paper for robotic application.Micro needle layer made of polydimethylsiloxane(PDMS)is sandwiched between the upper electrode layer made of PDMS and the bottom electrode layer fabricated on polyester(PET)film.The PDMS material renders the device adequate flexibility as it can be rolled into a cylinder.The single cell size in the fabricated 4×4 sensors array is 0.7×0.5 cm2and the initial capacitance of each cell is 0.86 p F.The fabricated cell shows a sensitivity of 3.26%/m N within the full scale range of 1 k Pa.The micro needle structure gives better repeatability and stability.The maximum error during each measurement is about 3.2%,while the minimum error is about 1.2%.HU XiaoHui ZHANG Xu LIU Ming CHEN YuanFang LI Peng PEI WeiHua ZHANG Chun CHEN HongDa 2014Science China(Information Sciences)2014,57,12:9
4Clinicopathological analysis of metaplastic meningioma: report of 15 cases in Huashan Hospital显示文摘Objective: Metaplastic meningioma is a rare subtype of benign meningiomas, classified as WHO grade I with well prognosis. Here we presented our experiences on 15 cases of metaplastic meningioma, to investigate the clinicopathological features, therapies and prognosis of these cases. Methods: 15 patients underwent surgical treatment for intracranial metaplastic meningioma between 2001 and 2010 at Neurosurgery Department of Huashan Hospital, Shanghai, China. The clinical data, radiological manifestation, treatment strategy, pathological findings and prognosis of all patients were analyzed retrospectively. Results: Among the 15 cases (10 males and 5 females), the age ranged from 22 to 74 years old (the mean age was 50.67-year old). The clinical manifestations include headache, dizziness, seizure attack, vision decrease, and weakness of bilateral lower limbs. All the patients received surgical treatment, combined with radiotherapy in some cases. In the follow-up period, recurrence occurred in 2 cases, of which 1 patient died of other system complications. Conclusions: Metaplastic meningiomas are characterized by focal or widespread mesenchymal differentiation with formation of bone, cartilage, fat, and xanthomatous tissue elements. Surgical removal is the optimal therapy, and the overall prognosis is well. But recurrence may occur in some cases, thus radiotherapy is necessary for such kind of patients.Hailiang Tang Huaping Sun Hong Chen Ye Gong Ying Mao Qing Xie Liqian Xie Mingzhe Zheng Daijun Wang Hongda Zhu Xiaoming Che Ping Zhong Kang Zheng Shiqi Li Weimin Bao Jianhong Zhu Xuanchun Wang Xiaoyuan Feng Xiancheng Chen Liangfu Zhou 2013Chinese Journal of Cancer Research2013,25,1:6
5Dry electrode for the measurement of biopotential signals显示文摘This paper introduces a kind of silicon-based dry electrode for measuring biological signals.It uses microneedle arrays to penetrate into the stratum corneum to reduce skin impedance.The dry electrode requires neither skin preparation nor the electrolytic gel,is easy to use and causes no skin allergy.Two different technologies are chosen to manufacture microneedle arrays of dry electrode.One is deep dry etching combined with isotropic wet etching.The other is mechanical dicing combined with chemical wet etching (including isotropic wet etching and anisotropic wet etching).Microneedle arrays are coated with metal and divided into 25 mm 2 as dry electrode patch.Impedance testing shows that the impedance value of dry electrode can be comparable with that of commercial electrode in the 20 Hz-10 kHz frequency range.The steady-state visual evoked potential recording and analysis prove that the dry electrode can be used to detect electroencephalography.WANG Yu PEI WeiHua GUO Kai GUI Qiang LI XiaoQian CHEN HongDa YANG JianHong 2011Science China(Information Sciences)2011,54,11:6
6Experimental Study on Interaction Between Degrees of Freedom in a Wave Buoy显示文摘Increasing degrees of freedom(DOFs)is a useful way to raise the power capture efficiency of oscillating wave energy converters.Thus,this study proposes a buoy with three DOFs,which are surge,heave,and pitch.The hydrodynamic performance and power capture efficiency of the buoy is physically modeled.Amplitudes of unidirectional and coupled motions are compared to analyze the interaction effect between freedoms under conditions with and without power take-off damping.The capture width ratio and corresponding growth rates are also calculated.Results show that the buoy makes a periodic sinusoidal(or approximate)movement in every DOF.Coupling effect can cause an increase in the amplitude in one DOF and a decrease in the amplitudes of the others.This phenomenon shows that the kinematic energy of the buoy redistributes to all DOFs compared with the unidirectional conditions.Adding DOFs can improve the power absorption of the buoy in most cases,but the number of DOFs is not the more the better.HUANG Shuting SHI Hongda CAO Feifei TAN Junzhe CHENG Haixun LI Demin LIU Shangze GONG Haoxiang TAO Ji 2019Journal of Ocean University of China2019,18,6:5
7Lipid-dependent conformational dynamics underlie the functional versatility of T-cell receptor显示文摘T 房间 receptor-CD3 建筑群(TCR ) 是能基于 CD3 细胞质的领域的各种各样的生物化学的变化开始抗原特定的有免疫力的回答的一台万用的发信号机器,但是内在的结构的基础留下逃犯。这里,我们开发了生物物理的途径学习 CD3 细胞质的领域的 conformational 动力学(CD3 CD ) 。在单个分子的水平,我们发现那 CD3 CD 能与三个功能的主题的不同坦诚有多重 conformational 状态,即, ITAM, BRS 和 PRS。因为,这些符合构造被产生 CD3 CD 有异构的类脂化合物绑定性质因此有异构的动力学。实时房间的成像实验证明不同抗原刺激能稳定 CD3 在不同符合构造的 CD 。类脂化合物依赖者 conformational 动力学因此为 TCR 的万用的发信号性质提供结构的基础。Xingdong Guo Chengsong Yan Hua Li Wenmao Huan Xiaoshan Shi Min Huang Yingfang Wang Weiling Pan Mingjun Cai Lunyi Li Wei Wu Yibing Bai Chi Zhang Zhijun Liu Xinyan Wang Xiaohui F Zhang Chun Tang Hongda Wang Wanli Liu Bo Ouyang Catherine C Wong Yi Cao Chenqi Xu 2017Cell Research2017,27,4:5
8Global and regional trends in incidence and mortality of female breast cancer and associated factors at national level in 2000 to 2019显示文摘Background: Female breast cancer (FBC) has become the most prevalent malignancy worldwide. We aimed to evaluate the global and regional burden in epidemiological trends and factors associated with the incidence and mortality of FBC.Methods: FBC incidence and mortality in 60 selected countries by cancer registry data integrity in 2020 were estimated from the GLOBOCAN database, and their association with the human development index (HDI) was further evaluated. Trends of age-standardized rates of incidence and mortality in 60 countries from 2000 through 2019 were evaluated by joinpoint regression analysis using data of Global Burden of Disease 2019. The association between potential behavioral, metabolic, and socioeconomic risk factor exposure at the nation level retrieved from the World Bank and Global Health Observatory and the incidence and mortality of FBC were evaluated by multivariate linear regression.Results: FBC incidence and mortality varied greatly in the 60 included countries. Higher incidence and mortality rates were typically observed in countries with higher HDIs and vice versa. During 2000 to 2019, significantly increasing trends in incidence and mortality were observed in 26 (average annual percent changes [AAPCs], 0.35-2.96) and nine countries (AAPC, 0.30-1.65), respectively, while significantly decreasing trends in both incidence and mortality were observed in 22 countries, most of which were high-HDI countries. Among the population aged ≥40 years, there were 26 and 11 countries showing significantly increased trends in incidence and mortality, respectively. Ecological analysis showed that countries with higher prevalence rates of high cholesterol and higher health expenditures were more likely to have higher FBC incidence, and countries with higher rates of obesity and poorer universal health coverage were more likely to have higher FBC mortality.Conclusions: Despite decreased or stabilized FBC incidence and mortality rates were observed in some countries with high HDI over the past decades, disease burden became even severer in developing countries, especially for the population aged ≥40 years. Effective targeted preventive programs are strongly encouraged to reduce the FBC disease burden worldwide.Chenyu Luo Na Li Bin Lu Jie Cai Ming Lu Yuhan Zhang Hongda Chen Min Dai 2022Chinese Medical Journal2022,,1:5
9The Remote Sensing of Sargassum on Daya BayLi Tiefang (Center for Remote Sensing, Zhongshan University) Liu Huai, Fang Hongda (South China Sea Marine Environmental Monitoring Center, SOA) Dong Yuguo (Guangzhou Institute of New Techniques in Geology, Academic Sinica) 1990遥感信息1990,12,A02:5
10Novel wavelet neural network algorithm for continuous and noninvasive dynamic estimation of blood pressure from photoplethysmography显示文摘This paper proposes a novel wavelet neural network algorithm for the continuous and noninvasive dynamic estimation of blood pressure(BP). Unlike prior algorithms, the proposed algorithm capitalizes on the correlation between photoplethysmography(PPG) and BP. Complete BP waveforms are reconstructed based on PPG signals to extract systolic blood pressure(SBP) and diastolic blood pressure(DBP). To improve the robustness, Daubechies wavelet is implemented as the hidden layer node function for the neural network. An optimized neural network structure is proposed to reduce the computational complexity. Further, this paper investigates an inhomogeneous resilient backpropagation(IRBP) algorithm to calculate the weight of hidden layer nodes. The IRBP improves the convergence speed and reconstruction accuracy. Multiparameter intelligent monitoring in Intensive Care(MIMIC) databases, which contain a variety of physiological parameters captured from patient monitors, are used to validate this algorithm. The standard deviation σ between reconstructed and actual BP signals is 4.4797 mm Hg, which satisfies the American National Standards of the Association for the Advancement of Medical Instrumentation. The reconstructed BP waveform can be used to extract the SBP and DBP, whose standard deviations σ are 2.91 mm Hg and 2.41 mm Hg respectively.Peng LI Ming LIU Xu ZHANG Xiaohui HU Bo PANG Zhaolin YAO Hongda NHEN 2016Science China(Information Sciences)2016,59,4:5
11Group VB transition metal dichalcogenides for oxygen reduction reaction and strain-enhanced activity governed by p-orbital electrons of chalcogen显示文摘Developi ng alter native oxyge n reducti on reactio n (ORR) catalysts to replace precious Pt-based metals with abundant materials is the key challe nge of commercial application of fuel cells. Owing to their various compositi ons and tun able electronic properties, transition metal dichalcogenides (TMDs) have the great potential to realize high-efficiency catalysts for ORR. Here, various 3R-phase dichalcogenides of group VB and VIB transition metals (MX2, M = Nb, Ta, Mo, W;X = S, Se, Te) are investigated for ORR catalysts by using density functional theory calculations. The computed over-potentials of group VB TMDs are much less than those of group VIB TMDs. For group VB TMDs, a volcano-type plot of ORR catalytic activity is established on the adsorption energies of *OH, and NbS2 and TaTe2 exhibit best ORR activity with an oveepotential of 0.54 V. To achieve even better activity, strain engineering is performed to tune ORR catalytic activity, and the minimum over-potential of 0.43 V can be realized. We further dem on strate that the shift of p orbital center of surface chalcoge n elements under strain is responsible for tuning the catalytic activity of TMDs.Shuyang Zhao Ke Wang Xiaolong Zou Lin Gan Hongda Du Chengjun Xu Feiyu Kang Wenhui Duan Jia Li 2019Nano Research2019,12,4:4
12Characteristics of Breccias and C-O-Sr-S Isotope Geochemistry of the Duocaima Pb-Zn Deposit in Tuotuohe, Qinghai Province: Implications for the Ore-forming Process显示文摘The Duocaima carbonate-hosted Pb-Zn deposit is a newly found large deposit in the southern area of Qinghai Province.In this paper, the characteristics, genesis, significance to Pb-Zn mineralization of the widely developed breccias, and the ore-forming process have been carefully studied based on geological documentation of drilling holes, microscopic observations of petrography and microstructure and some stable isotope measurements.Based on the compositions of the clast and matrix, the breccias can be classified into three types: limestone clasts cemented by marl; limestone clasts with fine-grained calcareous materials; and limestone clasts cemented by hydrothermal calcite.The mineralization in the first type of breccia is weak, whereas it is strong in the latter two types of breccias.According to the locations of occurrence and structural characteristics of the breccias along with the relationship between the breccias and mineralization, part of the limestone clasts that are cemented by marl and outcrop in the contact zone between the Wudaoliang Formation(Nw) and the underlying Jiushidaoban Formation(Pj) are attributed to synsedimentary fault-genetic breccia, whereas the last of the limestone clasts that are cemented by marl and developed in the Jiushidaoban Formation(Pj) are attributed to the breccia generated by karst cave collapse; the limestone clasts with fine-grained calcareous materials and the limestone clasts cemented by hydrothermal calcite are attributed to breccia formed by hydrothermal dissolution.The breccia formed by karst collapse had consistently evolved for a long period of time, while the breccias with other origins were formed around the period of mineralization(i.e., about or slightly later than 20–16 Ma).The breccia generated by karst cave collapse and hydrothermal dissolution are somewhat related; the formation of the breccia from karst cave collapse provided open space for the later mineralization and reaction between hydrothermal fluids and host rocks, and the subsequent strong dissolution by hydrothermal fluids transformed some of the breccia formed earlier by karst cave collapse.Meanwhile, carbonate host rocks with breccias and brecciaed mineralization can be a potential sign of Mississippi Valley Type(MVT) deposits and important indicators for regional mineral exploration.The δ13CV-PDB, δ18OVSMOW, and 87Sr/86 Sr values of hydrothermal calcite in the Duocaima deposit range from 4.3‰ to 7.1‰, 14.9‰ to 20.1‰, and 0.707494 to 0.708185, respectively; the δ13CV-PDB, δ18OV-SMOW, and 87Sr/86 Sr values of the host limestones of the Jiushidaoban Formation range from 3.6‰ to 5.3‰, 18.0‰ to 20.5‰, and 0.707372 to 0.707945, respectively.The δ13CV-PDB and 87Sr/86 Sr values of hydrothermal calcite and limestone are similar, indicating single sources of C and Sr in this deposit, with the likely source being the limestone of the Jiushidaoban Formation.The minor scattering of the δ18OV-SMOW values suggests that different O isotope fluids underwent the isotope exchange reaction.The C-O-Sr isotope characteristics indicate that the host limestones experienced a dissolution and precipitation process during mineralization, which is beneficial to improving the porosity of host rocks and promoting the precipitation of metal sulfides.The δ34SV-CDT value of the breccia-type mineralization sulfides ranges from-30.4‰ to-0.3‰; that is, the δ34SV-CDT value is negative with considerable variation, illustrating that during the breccia-type mineralization process, the bacteriogenic reduction of sulfates provided the vast majority of sulfur, whereas the thermochemical reduction of sulfates was relatively unimportant.The brecciation that occurred as a result of karst cave collapse was mainly generated by the dissolution of groundwater; however, the brecciation related to hydrothermal dissolution and mineralization processes were caused by mixing of different fluids.HAO Hongda SONG Yucai LI Liansong JIA Zongyong WANG Yuankui LIU Qun 2015Acta Geologica Sinica(English Edition)2015,89,5:4
13Superior anti-corrosion and self-healing bi-functional polymer composite coatings with polydopamine modified mesoporous silica/graphene oxide显示文摘In this article,graphene oxide(GO)and benzotriazole-loaded mesoporous silica nanoparticles(BTA/MSNs)are combined on micro scale through the in situ polymerization of polydopamine(PDA),preparing a selfhealing bi-functional GO(fGO)used as nano-fillers for anti-corrosion enhancement of waterborne epoxy(WEP)coatings.Scanning electronic microscopy(SEM)images show that the BTA/MSNs are uniformly distributed on the surface of high aspect ratio GO nanosheets to endow GO nanocontainer characteristics.UV-vis profiles demonstrate that fGO has p H-controlled release function.Modulus at lowest frequency is generally used for comparing the corrosion resistance of organic coatings.Modulus at lowest frequency(1.42×10^(5)Ωcm^(2))after 30 days immersion in 3.5 wt.%Na Cl solution revealed 2 orders of magnitude higher that of blank WEP(1.17×10^(7)Ωcm^(2)).With artificial cracks on its coatings,fGO/WEP had no obvious rust compared with blank WEP after 240 h of immersion.We anticipate that self-healing and physical barrier bi-functional nanocontainers improve the traditional anticorrosion coating efficiency with better,longer-lasting performance for shipping,oil drilling or bridge maintenance.Yanqi Ma Haowei Huang Hongda Zhou Michael Graham James Smith Xinxin Sheng Ying Chen Li Zhang Xinya Zhang Elena Shchukina Dmitry Shchukin 2021Journal of Materials Science & Technology2021,,36:4
14Investigation of flexible electrodes modified by TiN,Pt black and IrO_x显示文摘TiN,platinum (Pt) black and iridium oxide are introduced to the stimulating sites to improve the performance of the flexible electrode.Low temperature process is used to fabricate the modifying films.TiN is coated on the gold sites by magnetron sputtering while platinum black and iridium oxide are coated by electroplating and electrodeposition,respectively.The im-pedance of the electrode decreases dramatically after modification.The combined analysis of surface morphology and cyclic voltammograms (CV) in phosphate buffer saline (PBS) solution indicates that the modified electrode sites have larger elec-trode-electrolyte capacitance and smaller faradic resistance than unmodified sites,thus they have smaller electrochemical im-pedances.LI XiaoQian PEI WeiHua TANG RongYu GUI Qiang GUO Kai WANG Yu CHEN HongDa 2011Science China(Technological Sciences)2011,54,9:4
15A novel approach framework based on statistics for reconstruction and heartrate estimation from PPG with heavy motion artifacts显示文摘One of the most important applications of photoplethysmography(PPG) signal is heartrate(HR)estimation. For its applications in wearable devices, motion artifact(MA) may be the most serious challenge for randomness both in format and temporal distribution. This paper proposes an advanced time-frequency analysis framework based on empirical mode decomposition(EMD) to select specific time slices for signal reconstruction. This framework operates with a type of pre-processing called variance characterization series(VCS), EMD, singular value decomposition(SVD), and a precise and adaptive 2-D filtration reported first.This filtration is based on Harr wavelet transform(HWT) and 3 rd order cumulant analysis, to make it have resolution in both the time domain and different components. The simulation results show that the proposed method gains 1.07 in absolute average error(AAE) and 1.87 in standard deviation(SD); AAEs' 1 st and 3 rd quartiles are 0.12 and 1.41, respectively. This framework is tested by the Physio Bank MIMIC II waveform database.Bo PANG Ming LIU Xu ZHANG Peng LI Hongda CHEN 2018Science China(Information Sciences)2018,61,2:4
16Infrared transition properties of vanadium dioxide thin films across semiconductor-metal transition显示文摘Vanadium dioxide thin films were fabricated through annealing vanadium oxide thin films deposited by dual ion beam sputtering. X-ray diffraction (XRD), atom force microscopy (AFM), and Fourier transform infrared spectrum (FTIR) were employed to measure the crystalline structure, surface morphology, and infrared optical transmittance. The phase transition properties were characterized by transmittance. The results show that the annealed vanadium oxide thin film is composed of monoclinic VO2, with preferred orientation of (011). The maximum of transmittance change is beyond 65% as the temperature increases from 20 to 80 C. The reversible changes in optical transmittance against temperature were observed. The change rate of transmittance at short wavelength is higher than that at long wavelength at the same temperature across semiconductor-metal phase transition. This phenomenon was discussed using diffraction effect.LIANG Jiran HU Ming KAN Qiang LIANG Xiuqin WANG Xiaodong LI Guike CHEN Hongda 2011Rare Metals2011,30,3:4
17Advances in Understanding Materials for Rechargeable Lithium Batteries by Atomic Force Microscopy显示文摘The development of advanced lithium batteries represents a major technological challenge for the new century.Understanding the fundamental electrode degradation mechanisms is important for battery performance improvements.The complex electrochemical processes inside a working battery are being explored to a limited extent.Various advanced material characterization techniques have been used to monitor dynamic conditions for optimizing battery materials.State-of-the-art atomic force microscopy methods have been applied to energy storage systems,specifically lithium-ion batteries.Atomic force microscopy is an ideal tool to provide localized morphological,chemical,and physical information at nanoscale for the in-depth understanding of the electrochemical processes,reaction mechanisms,and degradation of battery materials.Here,we review recent progress in the development and application of atomic force microscopy for high-performance lithium-ion batteries.We discuss atomic force microscopy as an analytical tool to help researchers understand graphite,silicon,layered metal oxides,and other representative electrode materials.We summarize the importance of atomic force microscopy technique in studying the next-generation Li–S and Li–O 2 batteries.We also highlight some of the remaining challenges and possible solutions for future development.Shuwei Wang Qi Liu Chenglong Zhao Fengzheng Lv Xianying Qin Hongda Du Feiyu Kang Baohua Li 2018Energy & Environmental Materials2018,1,1:4
18KLF4 is a tumor suppressor in anaplastic meningioma stem-like cells and human rneningiomas显示文摘Hailiang Tang Hongda Zhu Xuanchun Wang Lingyang Hua Jingrun Li Qing Xie Xiancheng Chen Tao Zhang Ye Gong 2017Journal of Molecular Cell Biology2017,9,4:3
19Implantable CMOS neuro-stimulus chip for visual prosthesis显示文摘A prototype chip with 2×2 pixels for implanting in blind patients affected by outer retinal degeneration is presented in this paper.This visual prosthesis chip imitates the degenerated photoreceptor cells,senses the incident light and stimulates the remaining healthy layers of retina or optic nerve.Each pixel integrates photodiode and stimulus pulse generator,converting the illumination on the eyes into 3-bit resolution bi-phasic current pulses.On-chip charge cancellation modules are used to discharge each electrode site for tissue safety.The prototype chip is designed and fabricated in 0.18-μm N-well CMOS (complementary metal oxide semiconductor) 1P6M Mix-signal process,with a ±2.5 V dual voltage supply.The functionality of the fabricated chip is demonstrated on anesthetized rabbits.Neural responses in visual cortex are successfully evoked by the neuro-stimulus chip through an on-board trigger interface and flexible electrode.ZHANG Xu PEI WeiHua HUANG BeiJu WANG ShuJing GUAN Ning GUO Kai WANG Yu GUI Qiang CHEN Jin WANG Kai WU HuiJuan LI XiaoXin LI Kai CHEN HongDa 2011Science China(Information Sciences)2011,54,4:3
20Carbonaceous Nanofibers-titanium Dioxide Nanocomposites: Synthesis and Use as a Platform for Removal of Dye Pollutants显示文摘A mild chemistry route was developed to prepare carbonaceous nanofibers-titanium dioxide(CNF-TiO_2) nanocomposites for removal of dye pollutants. In the process of the template-directed hydrothermal carbonization(HTC), ultrathin Te nanowires were adopted as templates and glucose as the carbon source, and TiO_2 was decorated on CNF via the hydrolysis of tetrabutyltitanate in the presence of CNF in ethanol. The as-prepared materials were characterized by scanning electron microscopy(SEM), transmission electron microscopy(TEM), energy-dispersive X-ray(EDX) and X-ray diffraction(XRD). SEM and TEM observations displayed that TiO_2 nanoparticles were anchored on the CNF. EDX and XRD data confirmed that the assynthesized samples were CNF-TiO_2, and TiO_2 belonged to anatase titania. Taking advantage of combined benefits of carbonaceous nanofibers and titanium dioxide, these CNF-TiO_2 nanocomposites exhibited higher removal efficiency in a short time and showed good reusability. It was showed that over 97% of Rhodamine B could be removed in 15 min without generating the solid and liquid wastes. The removal efficiency of dyes was still over 80% after reuse in five cycles. All the results demonstrate that the as-prepared CNF-TiO_2 composites are effective materials for fast and effective removal of dye pollutants and thus can provide a new platform for dye decontamination.郭洪影 JIANG Shan WANG Chaoyuan LI Shenwan FENG Jianjian 孙红梅 ZHU Hongda GUO Huiling LIU Mingxing SUN Honghao 2019Journal of Wuhan University of Technology(Materials Science)2019,34,2:3
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