|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A chromosome-scale genome assembly of Isatis indigotica,an important medicinal plant used in traditional Chinese medicine显示文摘Isatis indigotica(2n=14)is an important medicinal plant in China.Its dried leaves and roots(called Isatidis Folium and Isatidis Radix,respectively)are broadly used in traditional Chinese medicine for curing diseases caused by bacteria and viruses such as influenza and viral pneumonia.Various classes of compounds isolated from this species have been identified as effective ingredients.Previous studies based on transcriptomes revealed only a few candidate genes for the biosynthesis of these active compounds in this medicinal plant.Here,we report a high-quality chromosome-scale genome assembly of I.indigotica with a total size of 293.88 Mb and scaffold N50=36.16 Mb using single-molecule real-time long reads and high-throughput chromosome conformation capture techniques.We annotated 30,323 highconfidence protein-coding genes.Based on homolog searching and functional annotations,we identified many candidate genes involved in the biosynthesis of main active components such as indoles,terpenoids,and phenylpropanoids.In addition,we found that some key enzyme-coding gene families related to the biosynthesis of these components were expanded due to tandem duplications,which likely drove the production of these major active compounds and explained why I.indigotica has excellent antibacterial and antiviral activities.Our results highlighted the importance of genome sequencing in identifying candidate genes for metabolite synthesis in medicinal plants. | Minghui Kang Haolin Wu Qiao Yang Li Huang Quanjun Hu Tao Ma Zaiyun Li Jianquan Liu | 2020 | Horticulture Research2020，7，1： | 9 |
| 2 | Re-Os Dating of Molybdenite from the Yaogangxian Tungsten Deposit,South China,and Its Geological Significance显示文摘Yaogangxian 钨存款位于 Nanling polymetallic metallogenic 省的中央部分。orebodies 作为静脉发生。黑钨矿和辉钼矿是主导的矿石矿物质。二件样品为标明日期预定矿化作用以便阐明的辉钼矿 Re-Os 被选择。从石英黑钨矿静脉的辉钼矿的 Re-Os datings 并且在 153 散猠' ?獡愠 ' 詳?湡 ? 湩敶獲? 楬扭 ? 景愠瑮捩楬敮 ? 愠摮映牯敭 ? 慭獳癩? 湡 ? 敶湩漠敲 ? 的花岗石收益年龄传播了?档愠 ? 桴 ? 楊湡慹潧 ? 湡 ? 敄杮楪獡慨 ? 祴数搠灥獯瑩? | WANG Yonglei PEI Rongfu LI Jinwen QU Wenjun LI Li WANG Haolin DU Andao | 2008 | Acta Geologica Sinica(English Edition)2008，82，4： | 8 |
| 3 | Analysis of users’ electricity consumption behavior based on ensemble clustering显示文摘Due to the increase in the number of smart meter devices,a power grid generates a large amount of data.Analyzing the data can help in understanding the users’electricity consumption behavior and demands;thus,enabling better service to be provided to them.Performing power load profile clustering is the basis for mining the users’electricity consumption behavior.By examining the complexity,randomness,and uncertainty of the users’electricity consumption behavior,this paper proposes an ensemble clustering method to analyze this behavior.First,principle component analysis(PCA)is used to reduce the dimensions of the data.Subsequently,the single clustering method is used,and the majority is selected for integrated clustering.As a result,the users’electricity consumption behavior is classified into different modes,and their characteristics are analyzed in detail.This paper examines the electricity power data of 19 real users in China for simulation purposes.This manuscript provides a thorough analysis along with suggestions for the users’weekly electricity consumption behavior.The results verify the effectiveness of the proposed method. | Qi Zhao Haolin Li Xinying Wang Tianjiao Pu Jiye Wang | 2019 | Global Energy Interconnection2019，2，6： | 7 |
| 4 | An efficient bifunctional electrocatalyst derived from layer-by-layer self-assembly of a three-dimensional porous Co-N-C@graphene显示文摘Three-dimensional (3D) porous carbon-based materials with tunable composition and microstructure are of great interest for the development of oxygen involved electrocatalytic reactions. Here, we report the synthesis of 3D porous carbon-based electrocatalyst by self-assembling Co-metal organic frameworks (MOF) building blocks on graphene via a layer-by-layer technique. Precise control of the structure and morphology is achieved by varying the MOF layer to tune the electrocatalytic properties. The as-produced electrocatalyst exhibits an excellent catalytic activity for the oxygen reduction reaction in 0.1molL^-1 KOH, showing a high onset potential of 0.963V vs. reversible hydrogen electrode (RHE) and a low tafel slope of 54mVdec^-1, compared to Pt/C (0.934V and 52mVdec^-1, respectively). Additionally, it shows a slightly lower potential vs. RHE (1.72V) than RuO2 (1.75V) at 10mAcm^-2 in an alkaline electrolyte. A rechargeable Zn-air battery based on the as-produced 3D porous catalyst demonstrates a high peak power density of 119mWcm^-2 at a cell voltage of 0.578V while retaining an excellent stability over 250 charge-discharge cycles. | Shichang Cai Rui Wang William M. Yourey Junsheng Li Haining Zhang Haolin Tang | 2019 | Science Bulletin2019，64，14： | 6 |
| 5 | MicroRNA-132 in the Adult Dentate Gyrus is Involved in Opioid Addiction Via Modifying the Differentiation of Neural Stem Cells显示文摘MicroRNA-132(miR-132), a small RNA that regulates gene expression, is known to promote neurogenesis in the embryonic nervous system and adult brain.Although exposure to psychoactive substances can increase miR-132 expression in cultured neural stem cells(NSCs)and the adult brain of rodents, little is known about its role in opioid addiction. So, we set out to determine the effect of miR-132 on differentiation of the NSCs and whether this effect is involved in opioid addiction using the rat morphine self-administration(MSA) model. We found that miR-132 overexpression enhanced the differentiation of NSCs in vivo and in vitro. Similarly, speci?c overexpression of miR-132 in NSCs of the adult hippocampal dentate gyrus(DG) during the acquisition stage of MSA potentiated morphine-seeking behavior. These ?ndings indicate that miR-132 is involved in opioid addiction,probably by promoting the differentiation of NSCs in the adult DG. | Meng Jia Xuewei Wang Haolin Zhang Can Ye Hui Ma Mingda Yang Yijing Li Cailian Cui | 2019 | Neuroscience Bulletin2019，35，3： | 6 |
| 6 | Geology, Geochemistry, and Geochronology of the Fenghuangshan Skarn-type Copper Deposit in the Tongling Ore Cluster, Anhui Province, East China显示文摘The Fenghuangshan skarn-type Cu deposit, Tongling Ore Cluster, Anhui Province, is an important component in the Middle-Lower Yangtze River ore-forming belt. To better understand magmatism and its relationship to mineralization, we investigated geochemical features, ore-forming fluids, and geochronology of the Xinwuli intrusion and the related Fenghuangshan Cu deposit. Lithogeochemical characteristics show that the Xinwuli quartz monzodiorite is formed by mixing magma derived from upper mantle alkaline basalt that has been contaminated by crust materials. C, H and O isotopes indicate that ore-forming fluids mainly come from the magma, with minor amounts of meteoric fluids involved at the late stage. S and Pb isotopic components indicate that ore-forming materials are derived from the mantle. Molybdenite Re-Os isotopic dating yields Re-Os model ages ranging from 139.1±2.4 Ma to 142.0±2.2 Ma, with an isochronal age of 141.1±1.4 Ma, which is consistent with sensitive, high-resolution ion microprobe (SHRIMP) zircon U-Pb ages of quartz monzodiorite and granodiorite in the mining area. Dating analysis yields ages from 136.0±2.0 Ma to 143.0±2.4 Ma for the quartz monzodiorite (a weighted average of 139.4±1.2 Ma) and ages from 136.7±2.0 Ma to 145.3±2.4 Ma for granodiorite (a weighted average of 141.0±1.1 Ma). | QU Hongying PEI Rongfu FEI Hongcai LI Jinwen WANG Yonglei WANG Haolin YAO Lei | 2012 | Acta Geologica Sinica(English Edition)2012，86，3： | 3 |
| 7 | Adsorptive Behavior of Methyl Blue on Graphene Aerogel:A Mechanism Study显示文摘Graphene aerogel was synthesized and used for the removal of methyl blue from aqueous solutions.The effect of solution pH,temperature and adsorption time on the adsorption performance of the graphene aerogel was studied systematically.In addition,investigations were also performed to determine the nature of adsorption.The experimental results show that graphene aerogel is a highly efficient adsorbent for the treatment of methyl blue in aqueous solutions.In addition,the adsorption of methyl blue proceeds through a single layer physical adsorption on the graphene aerogel.The findings herein are useful for the future development of adsorbent for in water. | 宋旭艳 HE Yunlu PAN Xi WEI Min LI Ran ZHOU Xiaoyu 郑莹 李俊升 TANG Haolin | 2021 | Journal of Wuhan University of Technology(Materials Science)2021，36，2： | 2 |
| 8 | Application of fast factorized back-projection algorithm for high-resolution highly squinted airborne SAR imaging显示文摘In squinted synthetic aperture radar(SAR) imaging, the range-azimuth coupling requires precise range cell migration correction(RCMC). Moreover, for high-resolution airborne SAR, motion compensation(MOCO) becomes complicated as the squint angle increases, thereby degrading the performance of Dopplerdomain imaging algorithms. On the other hand, time-domain back-projection(BP) SAR imaging approaches are considered as optimal solutions to performing precise image focusing and MOCO. Among current BP algorithms,the fast factorized back-projection(FFBP) algorithm is one of the most essential representatives that achieve high-resolution images in an efficient manner. In this paper, the principle and applications of the FFBP algorithm are investigated through the derivation of the azimuth impulse response function(AIRF) of the resulting image.The phenomenon of spectrum displacement induced by motion errors in the BP image is presented and analyzed.Based on rigorous mathematical derivations, a modified FFBP algorithm is proposed to facilitate a seamless integration with motion compensation and accurate imagery of high-resolution highly squinted airborne SAR.Real data results confirm the effectiveness of the proposed approaches. | Lei ZHANG Haolin LI Zhiwei XU Hongxian WANG | 2017 | Science China(Information Sciences)2017，60，6： | 2 |
| 9 | Lamellar hafnium ditelluride as an ultrasensitive surface-enhanced Raman scattering platform for label-free detection of uric acid显示文摘The development of two-dimensional(2D)transition metal dichalcogenides has been in a rapid growth phase for the utilization in surface-enhanced Raman scattering(SERS)analysis.Here,we report a promising 2D transition metal tellurides(TMTs)material,hafnium ditelluride(HfTe2),as an ultrasensitive platform for Raman identification of trace molecules,which demonstrates extraordinary SERS activity in sensitivity,uniformity,and reproducibility.The highest Raman enhancement factor of 2.32×10^(6)is attained for a rhodamine 6G molecule through the highly efficient charge transfer process at the interface between the HfTe2 layered structure and the adsorbed molecules.At the same time,we provide an effective route for large-scale preparation of SERS substrates in practical applications via a facile stripping strategy.Further application of the nanosheets for reliable,rapid,and label-free SERS fingerprint analysis of uric acid molecules,one of the biomarkers associated with gout disease,is performed,which indicates arresting SERS signals with the limits of detection as low as 0.1 mmol/L.The study based on this type of 2D SERS substrate not only reveals the feasibility of applying TMTs to SERS analysis,but also paves the way for nanodiagnostics,especially early marker detection. | YANG LI HAOLIN CHEN YANXIAN GUO KANGKANG WANG YUE ZHANG PEILIN LAN JINHAO GUO WEN ZHANG HUIQING ZHONG ZHOUYI GUO ZHENGFEI ZHUANG ZHIMING LIU | 2021 | Photonics Research2021，9，6： | 2 |
| 10 | Effect of surgical factors on the augmentation of cementinjectable cannulated pedicle screw fixation by a novel calcium phosphate-based nanocomposite显示文摘Bone cement-augmented pedicle screw system demonstrates great efficacy in spinal disease treatments. However, the intrinsic drawbacks associated with clinically used polymethylmethacrylate (PMMA) cement demands for new bone cement formulations. On the basis of our previous studies, a novel injectable and biodegradable calcium phosphate-based nanocomposite (CPN) for the augmentation of pedicle screw fixation was systematically evaluated for its surgical feasibility and biomechanical performance by simulated and animal osteoporotic bone models, and the results were compared with those of clinical PMMA cement. ASTM-standard solid foam and open-cell foam models and decalcified sheep vertebra models were employed to evaluate the augmentation effects of CPN on bone tissue and on the cement-injected cannulated pedicle screws (CICPs) placed in osteoporotic bone. Surgical factors in CICPs application, such as injection force, tapping technique, screw diameter, and pedicle screw loosening scenarios, were studied in comparison with those in PMMA. When directly injected to the solid foam model, CPN revealed an identical augmentation effect to that of PMMA, as shown by the similar compressive strengths (0.73 ± 0.04 MPa for CPN group vs. 0.79 ± 0.02 MPa for PMMA group). The average injection force of CPN at approximately 40-50 N was higher than that of PMMA at approximately 20 N. Although both values are acceptable to surgeons, CPN revealed a more consistent injection force pattern than did PMMA. The dispersing and anti-pullout ability of CPN were not affected by the surgical factors of tapping technique and screw diameter. The axial pullout strength of CPN evaluated by the decalcified sheep vertebra model revealed a similar augmentation level as that of PMMA (1351.6 ± 324.2 N for CPN vs. 1459.7 ± 304.4 N for PMMA). The promising results of CPN clearly suggest its potential for replacing PMMA in CICPs augmentation application and the benefits of further study and development for clinical uses. | Haolin Sun Chun Liu Shunlun Chen Yanjie Bai Huilin Yang Chunde Li Lei Yang | 2019 | Frontiers of Medicine2019，13，5： | 2 |
| 11 | Polycyclic aromatic hydrocarbons (PAHs) in soils and vegetation near an e-waste recycling site in South China: Concentration, distribution, source, and risk assessment显示文摘 | Yan Wang Zhongjing Tian Haolin Zhu Zhineng Cheng Meiling Kang Chunling Luo Jun Li Gan Zhang | 2012 | Science of the Total Environment2012，，： | 1 |
| 12 | Pervasive hybridization during evolutionary radiation of Rhododendron subgenus Hymenanthes in mountains of southwest China显示文摘Radiations are especially important for generating species biodiversity in mountainous ecosystems.The contribution of hybridization to such radiations has rarely been examined.Here,we use extensive genomic data to test whether hybridization was involved in evolutionary radiation within Rhododendron subgenus Hymenanthes,whose members show strong geographic isolation in the mountains of southwest China.We sequenced genomes for 143 species of this subgenus and 93 species of four other subgenera,and found that Hymenanthes was monophyletic and radiated during the late Oligocene to middle Miocene.Widespread hybridization events were inferred within and between the identified clades and subclades.This suggests that hybridization occurred both early and late during diversification of subgenus Hymenan thes,although the extent to which hybridization,speciation through mixing-isolation-mixing or hybrid speciation,accelerated the diversification needs further exploration.Cycles of isolation and contact in such and other montane ecosystems may have together promoted species radiation through hybridization between diverging populations and species.Similar radiation processes may apply to other montane floras in this region and elsewhere. | Yazhen Ma Xingxing Mao Ji Wang Lei Zhang Yuanzhong Jiang Yuying Geng Tao Ma Liming Cai Shuangquan Huang Pete Hollingsworth Kangshan Mao Minghui Kang Yiling Li Wenlu Yang Haolin Wu Yang Chen Charles C.Davis Nawal Shrestha Richard H.Ree Zhenxiang Xi Quanjun Hu Richard I.Milne Jianquan Liu | 2022 | National Science Review2022，9，12： | 1 |
| 13 | Two-Dimensional Tidal Current and Sediment Mathematical Model for Oujiang Estuary and Wenzhou Bay显示文摘 | Lu Yongjun Li Haolin Dong Zhuang | 2002 | China Ocean Engineering2002，16，1： | 1 |
| 14 | Early experience of performing a modified Kugel hernia repair with local anesthesia显示文摘 | Li Junsheng Zhang Yanan Hu Haolin | 2008 | Surg Today2008，38，7： | 1 |
| 15 | A literature review of smart warehouse operations management显示文摘E-commerce,new retail,and other changes have highlighted the requirement of high efficiency and accuracy in the logistics service.As an important section in logistics and supply chain management,warehouses need to respond positively to the increasing requirement.The“smart warehouse”system,which is equipped with emerging warehousing technologies,is increasingly attracting the attention of industry and technology giants as an efficient solution for the future of warehouse development.This study provides a holistic view of operations management problems within the context of smart warehouses.We provide a framework to review smart warehouse operations management based on the characteristics of smart warehouses,including the perspectives of information interconnection,equipment automation,process integration,and environmental sustainability.A comprehensive review of relevant literature is then carried out based on the framework with four perspectives.This study could provide future research directions on smart warehouses for academia and industry practitioners. | Lu ZHEN Haolin LI | 2022 | Frontiers of Engineering Management2022，9，1： | 1 |
| 16 | Two-Dimensional Tidal Current and Sediment Mathematical Model for Oujiang Estuary and Wenzhou Bay显示文摘 | Lu Yongjun Li Haolin Dong Zhuang | 2002 | China Ocean Engineering2002，16，1： | 1 |
| 17 | Parallel grinding error for a noncoaxial nonaxisymmetric aspheric lens using a fixture with adjustable gradient显示文摘 | Jiang Chen Guo Yinbiao Li Haolin | 2013 | International Journal of Advanced manufacturing Technology2013，66，14： | 1 |
| 18 | Two-dimensional tidal current and sediment mathematical model for Oujiang estuary and Wenzhou bay显示文摘 | Lu Yongjun Li Haolin Dong Zhuang | 2002 | China Ocean Engineering2002，16，1： | 1 |
| 19 | Two-Dimensional tidal current and sediment mathematical model for oujiang estuary and wenzhou bay显示文摘 | Lu Yongjun Li Haolin Dong Zhuang | 2002 | China Ocean Engineering2002，16，1： | 1 |
| 20 | Two - Dimensional Tidal Current and Sediment Mathematical for Oujiang Estuary and Wenzhou Bay显示文摘 | Lu Yongjun Li Haolin Dong Zhuang 2002 | 2002 | China Ocean Engineering2002，16，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员